Arthur Riggs Diabetes and Metabolism Research Institute 1 article published in JoVE Biology Generating Human Pancreatic Tissue Slices to Study Endocrine and Exocrine Pancreas Physiology Julia K. Panzer1, Pablo A. Garcia1, Alberto Pugliese1 1Department of Diabetes Immunology, Arthur Riggs Diabetes and Metabolism Research Institute This protocol describes how to generate human pancreas slices from deceased organ donors to study cell function under near-physiological conditions. This innovative approach enables the investigation of normal and structurally damaged islets and the intricate interplay between endocrine and exocrine compartments.
