Seroclinix Corporation 1 article published in JoVE Chemistry High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry Meera Shanmuganathan1, Sabrina Macklai1, Clara Barrenas Cárdenas1, Zachary Kroezen1, Marcus Kim2, William Zizek3, Howard Lee3, Philip Britz-McKibbin1 1Department of Chemistry and Chemical Biology, McMaster University, 2Agilent Technologies Inc., 3Seroclinix Corporation Here we describe a high-throughput method for comprehensive drug surveillance that allows for the improved resolution and detection of large panels of drugs of abuse and their metabolites, with quality control based on multisegment injection-capillary electrophoresis-mass spectrometry.