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Bioengineering

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JoVE Journal Bioengineering
Plasma Lithography Surface Patterning for Creation of Cell Networks
 
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Plasma Lithography Surface Patterning for Creation of Cell Networks

Article DOI: 10.3791/3115-v • 05:58 min • June 14th, 2011
June 14th, 2011 •
1, 1, 1, 1, 1, 1,2
1Aerospace and Mechanical Engineering, University of Arizona, 2Biomedical Engineering IDP and BIO5 Institute, University of Arizona

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A versatile plasma lithography technique has been developed to generate stable surface patterns for guiding cellular attachment. This technique can be applied to create cell networks including those that mimic natural tissues and has been used for studying several, distinct cell types.

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Plasma Lithography Surface Patterning Cell Networks Microenvironment Manipulation Feature Sizes Selective Modification Surface Chemistry Low-temperature Plasma Physical Mold Chemical Pattern Cell Attachment Cell Movement Surface Template Networks Of Cells Experimental Investigations Stable Surface Patterns Transparent Polymeric Substrates Biocompatible Manner Long-term Cellular Processes
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