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1Department of Chemical and Biological Engineering,Illinois Institute of Technology, 2Department of Biomedical Engineering,Illinois Institute of Technology, 3Department of Biomedical Engineering,University of California at Irvine, 4Wake Forest Institute for Regenerative Medicine and Department of Biomedical Engineering,Wake Forest University Health Sciences, 5Research Service,Hines Veterans Administration Hospital
Chapitres
- 00:05Titre
- 01:37Alginate Microbead Preparation
- 04:46Coating the Microbeads with Poly-L-ornithine
- 07:59Creating the Outer Alginate Layer
- 09:22Representative Results
Nas seções seguintes, que definirá procedimentos para a preparação de microesferas de alginato para uso em aplicações biomédicas. Nós especificamente ilustram uma técnica para a criação de várias camadas de alginato microesferas para a dupla finalidade de célula e de encapsulamento proteína como um tratamento potencial para a diabetes tipo 1.
Tags
Alginate MicrospheresBiomedical ApplicationsHydrophilic NatureBiocompatibilityPhysical ArchitectureCell EncapsulationDrug DeliveryStem Cell CultureIslets EncapsulationType I Diabetes TreatmentMicrovascular Network FormationOxygen TransportGlucose TransportVital Nutrients TransportFibroblast Growth Factor-1 (FGF-1)Sustained ReleaseGrowth Factor DeliveryBlood Vessel FormationFunctional Graft Outcomes
