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Neuroscience

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Motor Nerve Transection and Time-lapse Imaging of Glial Cell Behaviors in Live Zebrafish
 

Motor Nerve Transection and Time-lapse Imaging of Glial Cell Behaviors in Live Zebrafish

Article DOI: 10.3791/50621-v 09:05 min June 20th, 2013
June 20th, 2013

Chapitres

résumé

Although the peripheral nervous system (PNS) is capable of significant repair after injury, little is known about the cellular and molecular mechanisms that govern this phenomenon. Using live, transgenic zebrafish and a reproducible nerve transection assay, we can study dynamic glial cell behaviors during nerve degeneration and regeneration.

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Keywords: Motor Nerve Transection Time-lapse Imaging Glial Cell Behaviors Zebrafish Peripheral Nervous System Regeneration Axon Schwann Cells Perineurium Axotomy In Vivo Imaging Genetic Manipulation
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