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- 00:00Introduction to Caenorhabditis elegans
- 00:41Classification, Habitat, and Lifespan
- 01:57C. elegans: A Model System for Research
- 04:20Key Discoveries from C. elegans Research
- 06:49Applications
- 08:34Summary
An Introduction to Caenorhabditis elegans
English
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Vue d'ensemble
Caenorhabditis elegans is a microscopic, soil-dwelling roundworm that has been powerfully used as a model organism since the early 1970’s. It was initially proposed as a model for developmental biology because of its invariant body plan, ease of genetic manipulation and low cost of maintenance. Since then C. elegans has rapidly grown in popularity and is now utilized in numerous research endeavors, from studying the forces at work during locomotion to studies of neural circuitry.
This video provides an overview of basic C. elegans biology, a timeline of the many milestones in its short but storied history, and finally a few exciting applications using C. elegans as a model organism.
Procédure
Caenorhabditis elegans, or "worms" to the scientists who study them, have revolutionized the way we approach genetic studies to understand how genes regulate cellular activities. The worm’s simple genetics, transparent body, and ease of cultivation makes them an ideal system for studying embryonic development, neuronal functions, lifespan and aging, and molecular basis of some human diseases. First, lets get to know C. elegans as a model organism. Caeno…
Divulgations
No conflicts of interest declared.
Transcription
Tags
Caenorhabditis ElegansGenetic StudiesGenesCellular ActivitiesEmbryonic DevelopmentNeuronal FunctionsLifespanAgingHuman DiseasesModel OrganismNematodaMulticellular OrganismsTransparent BodyHermaphroditesMatingSoil HabitatAgarose-containing Petri DishesE. Coli BacteriaLife SpanLarval StagesTemperaturePowerful Model Organism
Cite This
JoVE Science Education Database. JoVE Science Education. An Introduction to Caenorhabditis elegans. JoVE, Cambridge, MA, (2023).
