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Urinary Bladder Distention Evoked Visceromotor Responses as a Model for Bladder Pain in Mice
 

Urinary Bladder Distention Evoked Visceromotor Responses as a Model for Bladder Pain in Mice

Article DOI: 10.3791/51413-v • 11:46 min • April 27th, 2014
April 27th, 2014 •
1, 1, 1
1Department of Biological Sciences and Chronic Pain Research Consortium, Duquesne University

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Approximately 3-8 million people in the United States suffer from interstitial cystitis/bladder pain syndrome (IC/BPS), a debilitating condition characterized in part by pelvic pain. In order to study nervous system contributions to the condition, a physiological model of urinary bladder pain is used in mice and rats.

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Keywords: Urinary Bladder Distension Visceromotor Response Interstitial Cystitis Bladder Pain Syndrome Nociception Murine Model Primary Sensory Neurons Spinal Cord Afferents Central Nervous System
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