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1Orthopaedic Hospital Research Center, Orthopaedic Hospital Department of Orthopaedic Surgery,David Geffen School of Medicine at University of California, Los Angeles (UCLA), 2PerkinElmer, 3Department of Dermatology,Johns Hopkins University School of Medicine, 4Department of Medicine, Division of Infectious Diseases, Department of Orthopaedic Surgery,Johns Hopkins University School of Medicine
Chapitres
- 00:05Titre
- 01:51Mouse Surgical Procedure
- 03:562D Optical Imaging (In vivo Bioluminescent and Fluorescent Imaging)
- 06:35µCT Image Acquisition
- 08:113D Optical Image Acquisition, Formation and µCT Co-registration
- 12:18µCT Image Analysis
- 16:09Results: Representative Bioluminescent and µCT Images
- 17:49Conclusion
Combinado imagiologia óptica e μCT num modelo de rato com infecção de implante ortopédico, utilizando uma estirpe bioluminescente engenharia de Staphylococcus aureus, desde a capacidade de forma não invasiva e longitudinalmente controlar a dinâmica da infecção bacteriana, assim como a resposta inflamatória correspondente e alterações anatómicas na osso.
