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界面聚电解质纤维的生物分子在时间控释复合支架
Journal JoVE
Bio-ingénierie
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Journal JoVE Bio-ingénierie
Composite Scaffolds of Interfacial Polyelectrolyte Fibers for Temporally Controlled Release of Biomolecules
DOI:

11:13 min

August 19, 2015

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Chapitres

  • 00:05Titre
  • 02:03Drawing of Interfacial Polyelectrolyte Complexation (IPC) Fibers
  • 03:43Fabrication of Pullulan-Dextran and IPC Fiber Composite Hydrogel Scaffolds
  • 06:36Fabrication of a Micro-patterned Polycaprolactone and IPC Fiber Composite
  • 08:25Results: Composite IPC Fiber Scaffolds Sustainably Release Bioactive Growth Factors
  • 10:03Conclusion

Summary

Traduction automatique

Scaffolds for tissue engineering need to recapitulate the complex biochemical and biophysical microenvironment of the cellular niche. Here, we show the use of interfacial polyelectrolyte complexation fibers as a platform to create composite, multi-component polymeric scaffolds with sustained biochemical release.

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