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A Neonatal Mouse Spinal Cord Compression Injury Model
 

A Neonatal Mouse Spinal Cord Compression Injury Model

Article DOI: 10.3791/53498-v • 13:32 min • March 27th, 2016
March 27th, 2016 •
1,2, 2,3, 2,3
1Department of Neurosurgery, Oslo University Hospital, 2Norwegian Center for Stem Cell Research, Oslo University Hospital, 3Laboratory of Neural Development and Optical Recording (NDEVOR), Department of Physiology, Institute of Basic Medical Sciences, University of Oslo

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This article describes a method for generating a reproducible spinal cord compression injury (SCI) in the neonatal mouse. The model provides an advantageous platform for studying mechanisms of adaptive plasticity that underlie spontaneous functional recovery.

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Neonatal Mouse Spinal Cord Compression Injury Reproducible Procedure Dorsal Laminectomy Compression Injury Adaptive Plasticity Mechanism Of Recovery Treatment Of Spinal Cord Injury Surgical Procedure Anesthesia Laminectomy Clip Driven Epidural Compressions Presurgical Analgesia Local Anesthetic Marcaine Sterile PBS Micro Knife Fine Forceps Fine Iridectomy Scissors
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