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Um Modelo de microfluidos de biomimetically respiração pulmonar acinares Airways
Journal JoVE
Bio-ingénierie
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Journal JoVE Bio-ingénierie
A Microfluidic Model of Biomimetically Breathing Pulmonary Acinar Airways
DOI:

09:39 min

May 09, 2016

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Chapitres

  • 00:05Titre
  • 00:54Preparation of the Microfluidic Device
  • 04:30Device Filling and Actuation
  • 06:21Micro-particle Image Velocimetry
  • 07:45Results: Imaging of Physiologically Realistic Flow Profiles
  • 09:02Conclusion

Summary

Traduction automatique

Soft-lithography was utilized to produce a representative true-scale model of pulmonary alveolated airways that expand and contract periodically, mimicking physiological breathing motion. This platform recreates respiratory acinar flows on a chip, and is anticipated to facilitate experimental investigation of inhaled aerosol dynamics and deposition in the pulmonary acinus.

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