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PET and MRI Guided Irradiation of a Glioblastoma Rat Model Using a Micro-irradiator
Journal JoVE
Recherche en cancérologie
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Journal JoVE Recherche en cancérologie
PET and MRI Guided Irradiation of a Glioblastoma Rat Model Using a Micro-irradiator
DOI:

10:48 min

December 28, 2017

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Chapitres

  • 00:05Titre
  • 00:53F98 Glioblastoma (GB) Rat Cell Model
  • 02:12Tumor Growth Confirmation
  • 03:26Multimodality Imaging for Target Volume Selection
  • 05:18Radiation Therapy (RT) Treatment Planning
  • 09:07Results: Representative Selected MRI and PET-guided Isocenters for Irradiation
  • 10:11Conclusion

Summary

Traduction automatique

In the past, small animal irradiation was usually performed without the ability to target a well-delineated tumor volume. The goal was to mimic the treatment of human glioblastoma in rats. Using a small animal irradiation platform, we performed MRI-guided 3D conformal irradiation with PET-based sub-volume boosting in a preclinical setting.

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