This content is Free Access.
1Department of Neurobiology, F. M. Kirby Neurobiology Center,Boston Children’s Hospital, Harvard Medical School, 2Proteomic Mass Spectrometry,Wellcome Trust Sanger Institute, Wellcome Genome Campus, 3Centre for Molecular Informatics, Department of Chemistry,University of Cambridge, 4Functional Proteomics Group, Chester Beatty Laboratories,Institute of Cancer Research
Chapitres
- 00:05Titre
- 00:51Mapping of Peptides using PoGoGUI
- 02:36Visualizing in the Integrative Genomics Viewer
- 03:57Mapping Peptides Identified Through a Custom Variant Database to a Reference Genome
- 04:44Mapping Peptides from Multiple Files Using PoGoGUI
- 05:48Generating a Track Hub from Mapped Peptides and Visualizing a Track Hub in the UCSC Genome Browser
- 06:50Results: Post-translational Modification and Varient Enabled Mapping of Peptides to Genomes
- 08:21Conclusion
Qui vi presentiamo lo strumento proteogenomic PoGo e protocolli per la modifica veloce, quantitativa e post-traduzionale e variante attivato mapping dei peptidi identificati mediante spettrometria di massa sul genoma di riferimento. Questo strumento è utile per integrare e visualizzare proteogenomic e studi di proteomica personali interfacciamento con dati di genomica ortogonale.
