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Immunologie et infection

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单方支气管内酸灌输自我限制急性肺损伤模型

Journal JoVE
Immunologie et infection

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Journal JoVE Immunologie et infection

A Model of Self-limited Acute Lung Injury by Unilateral Intra-bronchial Acid Instillation

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单方支气管内酸灌输自我限制急性肺损伤模型

DOI:

10.3791/60024-v

•

00:07 min

•

August 30, 2019

•

Alexander H. Tavares, Jennifer K. Colby, Bruce D. Levy, Raja-Elie Edward Abdulnour

¹Pulmonary and Critical Care Medicine, Department of Internal Medicine,Brigham and Women’s Hospital, Harvard Medical School

Chapitres

00:04Titre
00:53Hydrochloric Acid (HCL) Preparation
01:39Surgical Preparation
03:46Selective Intra-Bronchial HCL Instillation
05:11Résultats
06:38Conclusion

Summary

Traduction automatique

选择性支气管内酸在小鼠左肺中灌输会导致单侧和自我有限的急性肺损伤，从而模拟胃酸吸入引起的人类急性呼吸窘迫综合征（ARDS）。

Tags

Acute Lung Injury Intra-bronchial Instillation Nonlethal Model Inflammatory Response Hydrochloric Acid Anesthetized Mouse Trachea Surgical Procedure

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