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A Murine Model of a Burn Wound Reconstructed with an Allogeneic Skin Graft
 

A Murine Model of a Burn Wound Reconstructed with an Allogeneic Skin Graft

Article DOI: 10.3791/61339-v • 12:18 min • August 8th, 2020
August 8th, 2020 •
*1,2, *1,2, 2, 1, 1,2
1Laboratoire de Physique des Plasmas, École Polytechnique, Sorbonne Université, CNRS, 2Institut de Recherche Biomédicale des Armées, Clamart, INSERM UMRS-MD
* These authors contributed equally

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The aim of this study was to develop a murine model of burn wound healing. A thermal burn was induced on the dorsal skin of mice using a preheated brass template. Burned tissue was debrided and overlaid with a skin graft harvested from the tail of a genetically similar donor mouse.

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Murine Model Burn Wound Allogeneic Skin Graft Reproducible Epidermis Dermis Subcutaneous Fat Thickness Classification Superficial Burn Superficial Partial Thickness Burn Deep Dermal Partial Thickness Burn Full Thickness Burn Contraction Skin Grafting Circular Brass Block Necrotic Tissue Excised Burn Wounds Donor Mouse Tail Grafts Surgical Adhesive
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