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Electrocardiogram Recordings in Anesthetized Mice using Lead II
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Journal JoVE Médecine
Electrocardiogram Recordings in Anesthetized Mice using Lead II

Electrocardiogram Recordings in Anesthetized Mice using Lead II

DOI:
10.3791/61583-v

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04:16 min

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June 20, 2020

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, ,
1Department of Biochemistry and Molecular Biology, School of Medicine,Kyung Hee University

Chapitres

  • 00:00Introduction
  • 00:56ECG Measurement
  • 02:38Results: ECG Measurements in Mice Treated with Agonists and Antagonists of the Autonomic Nervous System
  • 03:25Conclusion

Summary

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Traduction automatique

We present an ECG protocol that is technically easy, inexpensive, fast, and affordable in small mice, and can be performed with enhanced sensitivity. We suggest this method as a screening approach for studying pharmacological agents, genetic modifications, and disease models in mice.

Tags

ElectrocardiogramECGAnesthetized MiceLead IICardiac ConductionArrhythmiaAutonomic Nervous SystemHeart RateQTc IntervalAtropineIsoprenalineCarbacholBALB/c MiceBio AmplifierData AcquisitionAnalysis Software

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