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Immunology and Infection

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JoVE Journal Immunology and Infection
Observing Islet Function and Islet-Immune Cell Interactions in Live Pancreatic Tissue Slices
 

Observing Islet Function and Islet-Immune Cell Interactions in Live Pancreatic Tissue Slices

Article DOI: 10.3791/62207-v • 05:51 min • April 12th, 2021
April 12th, 2021 •
1, 2,3,4, 1, 1, 1, 1, 2,3,4, 1, 1, 5
1Department of Pathology, Immunology, and Laboratory Medicine, University of Florida, 2Paul Langerhans Institute Dresden (PLID) of the Helmholtz Zentrum München at the University Clinic Carl Gustav Carus of Technische Universität Dresden, 3Institute of Physiology, Faculty of Medicine, Technische Universität Dresden, 4German Center for Diabetes Research (DZD), 5J. Crayton Pruitt Family Department of Biomedical Engineering, University of Florida

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This study presents the application of live pancreatic tissue slices to the study of islet physiology and islet-immune cell interactions.

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Keywords: Islet Function Islet-immune Cell Interactions Live Pancreatic Tissue Slices Pancreatic Illnesses Pancreatitis Type I Diabetes Type II Diabetes Vibratome Extracellular Solution Krebs-Ringer Bicarbonate Buffer Trypsin Inhibitor Slice Culture Medium Microscope Brightfield Mode Islets
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