Alonso Heredia Institute of Human Virology, School of Medicine University of Maryland Biography Publications Institution JoVE Articles Alonso Heredia has not added a biography. If you are Alonso Heredia and would like to personalize this page please email our Author Liaison for assistance. Publications Glycan-dependent HIV-specific Neutralizing Antibodies Bind to Cells of Uninfected Individuals The Journal of Clinical Investigation. Nov, 2019 | Pubmed ID: 31589168 CCR5 Inhibitors and HIV-1 Infection Journal of AIDS and HIV Treatment. 2019 | Pubmed ID: 31414081 Suppression of Active HIV-1 Infection in CD34 Hematopoietic Humanized NSG Mice by a Combination of Combined Antiretroviral Therapy and CCR5 Targeting Drugs AIDS Research and Human Retroviruses. Aug, 2019 | Pubmed ID: 31099257 Role of the Inflammasomes in HIV-associated Neuroinflammation and Neurocognitive Disorders Experimental and Molecular Pathology. Jun, 2019 | Pubmed ID: 30922769 Disparate Effects of Cytotoxic Chemotherapy on the Antiviral Activity of Antiretroviral Therapy: Implications for Treatments of HIV-infected Cancer Patients Antiviral Therapy. 2019 | Pubmed ID: 30574873 Targeting of CDK9 with Indirubin 3'-monoxime Safely and Durably Reduces HIV Viremia in Chronically Infected Humanized Mice PloS One. 2017 | Pubmed ID: 28817720 Monotherapy with Either Dolutegravir or Raltegravir Fails to Durably Suppress HIV Viraemia in Humanized Mice The Journal of Antimicrobial Chemotherapy. 09, 2017 | Pubmed ID: 28637235 Synergistic Inhibition of R5 HIV-1 by the Fusion Protein (FLSC) IgG1 Fc and Maraviroc in Primary Cells: Implications for Prevention and Treatment Current HIV Research. 2016 | Pubmed ID: 26354735 A Novel Small-molecule Inhibitor of HIV-1 Entry Drug Design, Development and Therapy. 2015 | Pubmed ID: 26491257 Targeting of MTOR Catalytic Site Inhibits Multiple Steps of the HIV-1 Lifecycle and Suppresses HIV-1 Viremia in Humanized Mice Proceedings of the National Academy of Sciences of the United States of America. Jul, 2015 | Pubmed ID: 26170311 Impact of HIV on Lung Tumorigenesis in an Animal Model AIDS (London, England). Mar, 2015 | Pubmed ID: 25611150 Binding of Fusion Protein FLSC IgG1 to CCR5 is Enhanced by CCR5 Antagonist Maraviroc Antiviral Research. Dec, 2014 | Pubmed ID: 25453341 Indirubin 3'-monoxime, from a Chinese Traditional Herbal Formula, Suppresses Viremia in Humanized Mice Infected with Multidrug-resistant HIV AIDS Research and Human Retroviruses. May, 2014 | Pubmed ID: 24401082 Targeting Host Nucleotide Biosynthesis with Resveratrol Inhibits Emtricitabine-resistant HIV-1 AIDS (London, England). Jan, 2014 | Pubmed ID: 24326355 Targeting of the Purine Biosynthesis Host Cell Pathway Enhances the Activity of Tenofovir Against Sensitive and Drug-resistant HIV-1 The Journal of Infectious Diseases. Dec, 2013 | Pubmed ID: 23922365 Synergistic Inhibition of R5 HIV-1 by Maraviroc and CCR5 Antibody HGS004 in Primary Cells: Implications for Treatment and Prevention AIDS (London, England). Jun, 2011 | Pubmed ID: 21505306 CCR5 Antibodies HGS004 and HGS101 Preferentially Inhibit Drug-bound CCR5 Infection and Restore Drug Sensitivity of Maraviroc-resistant HIV-1 in Primary Cells Virology. Mar, 2011 | Pubmed ID: 21232779 Pharmacotherapy of HIV-1 Infection: Focus on CCR5 Antagonist Maraviroc Clinical Medicine. Therapeutics. 2009 | Pubmed ID: 19920876 Rapamycin Enhances Aplaviroc Anti-HIV Activity: Implications for the Clinical Development of Novel CCR5 Antagonists Antiviral Research. Jul, 2009 | Pubmed ID: 19501260 Enzymatic Glycosylation of Triazole-linked GlcNAc/Glc-peptides: Synthesis, Stability and Anti-HIV Activity of Triazole-linked HIV-1 Gp41 Glycopeptide C34 Analogues Chembiochem : a European Journal of Chemical Biology. May, 2009 | Pubmed ID: 19353609 Reduction of CCR5 with Low-dose Rapamycin Enhances the Antiviral Activity of Vicriviroc Against Both Sensitive and Drug-resistant HIV-1 Proceedings of the National Academy of Sciences of the United States of America. Dec, 2008 | Pubmed ID: 19075241 An Alteration of Human Immunodeficiency Virus Gp41 Leads to Reduced CCR5 Dependence and CD4 Independence Journal of Virology. Jun, 2008 | Pubmed ID: 18353949 Rapamycin Reduces CCR5 MRNA Levels in Macaques: Potential Applications in HIV-1 Prevention and Treatment AIDS (London, England). Oct, 2007 | Pubmed ID: 17885304 CCR5 Density Levels on Primary CD4 T Cells Impact the Replication and Enfuvirtide Susceptibility of R5 HIV-1 AIDS (London, England). Jun, 2007 | Pubmed ID: 17545708 Rapamycin Reduces CCR5 Density Levels on CD4 T Cells, and This Effect Results in Potentiation of Enfuvirtide (T-20) Against R5 Strains of Human Immunodeficiency Virus Type 1 in Vitro Antimicrobial Agents and Chemotherapy. Jul, 2007 | Pubmed ID: 17485501 HIV-1 Natural Viral Suppressors: Control of Viral Replication in the Absence of Therapy AIDS (London, England). Feb, 2007 | Pubmed ID: 17301571 Indirubin-3'-monoxime, a Derivative of a Chinese Antileukemia Medicine, Inhibits P-TEFb Function and HIV-1 Replication AIDS (London, England). Dec, 2005 | Pubmed ID: 16284457 In Vitro Suppression of Latent HIV-1 Activation by Vitamin E: Potential Clinical Implications AIDS (London, England). May, 2005 | Pubmed ID: 15867501 Modification and Structure-activity Relationship of a Small Molecule HIV-1 Inhibitor Targeting the Viral Envelope Glycoprotein Gp120 Organic & Biomolecular Chemistry. May, 2005 | Pubmed ID: 15858664 Resveratrol Glucuronides As the Metabolites of Resveratrol in Humans: Characterization, Synthesis, and Anti-HIV Activity Journal of Pharmaceutical Sciences. Oct, 2004 | Pubmed ID: 15349955 Synthetic Bivalent CD4-mimetic Miniproteins Show Enhanced Anti-HIV Activity over the Monovalent Miniprotein Bioconjugate Chemistry. Jul-Aug, 2004 | Pubmed ID: 15264865 Design and Synthesis of Alpha Gal-conjugated Peptide T20 As Novel Antiviral Agent for HIV-immunotargeting Organic & Biomolecular Chemistry. Mar, 2004 | Pubmed ID: 14985805 Induction of G1 Cycle Arrest in T Lymphocytes Results in Increased Extracellular Levels of Beta-chemokines: a Strategy to Inhibit R5 HIV-1 Proceedings of the National Academy of Sciences of the United States of America. Apr, 2003 | Pubmed ID: 12644703 Chronic, Acute, and Reactivated HIV Infection in Humanized Immunodeficient Mouse Models Federico Perdomo-Celis1,2, Sandra Medina-Moreno1, Alonso Heredia1, Harry Davis1, Joseph Bryant1, Juan Carlos Zapata1 1Institute of Human Virology, School of Medicine, University of Maryland, 2Grupo Inmunovirología, Facultad de Medicina, Universidad de Antioquia JoVE 60315 Immunologia e infezioni
Chronic, Acute, and Reactivated HIV Infection in Humanized Immunodeficient Mouse Models Federico Perdomo-Celis1,2, Sandra Medina-Moreno1, Alonso Heredia1, Harry Davis1, Joseph Bryant1, Juan Carlos Zapata1 1Institute of Human Virology, School of Medicine, University of Maryland, 2Grupo Inmunovirología, Facultad de Medicina, Universidad de Antioquia JoVE 60315 Immunologia e infezioni