Andres J. P. Klein-Szanto Histopathology Facility Fox Chase Cancer Center Biography Publications Institution JoVE Articles Andres J. P. Klein-Szanto has not added a biography. If you are Andres J. P. Klein-Szanto and would like to personalize this page please email our Author Liaison for assistance. Publications Correction To: Overexpression of the HMGA2 Gene in Transgenic Mice Leads to the Onset of Pituitary Adenomas Oncogene. Dec, 2022 | Pubmed ID: 36544045 Paired Basic Amino Acid-cleaving Enzyme 4 (PCSK6): An Emerging New Target Molecule in Human Melanoma Acta Dermato-venereologica. May, 2020 | Pubmed ID: 32449780 Keep Recycling Going: New Approaches to Reduce LDL-C Biochemical Pharmacology. Jun, 2019 | Pubmed ID: 30953636 The Homeoprotein Dlx5 Drives Murine T-cell Lymphomagenesis by Directly Transactivating Notch and Upregulating Akt Signaling Oncotarget. Feb, 2017 | Pubmed ID: 28122332 Biofilm-associated Bacterial Amyloids Dampen Inflammation in the Gut: Oral Treatment with Curli Fibres Reduces the Severity of Hapten-induced Colitis in Mice NPJ Biofilms and Microbiomes. 2015 | Pubmed ID: 26855788 Involvement of MBD4 Inactivation in Mismatch Repair-deficient Tumorigenesis Oncotarget. Dec, 2015 | Pubmed ID: 26503472 PRMT5 is Required for Lymphomagenesis Triggered by Multiple Oncogenic Drivers Cancer Discovery. Mar, 2015 | Pubmed ID: 25582697 Psychosocial Functioning and Vascular Endothelial Growth Factor in Patients with Head and Neck Cancer Head & Neck. Aug, 2014 | Pubmed ID: 23804308 P21-Activated Kinase 1 is Required for Efficient Tumor Formation and Progression in a Ras-mediated Skin Cancer Model Cancer Research. Nov, 2012 | Pubmed ID: 22983922 Transgenic Overexpression of the Proprotein Convertase Furin Enhances Skin Tumor Growth Neoplasia (New York, N.Y.). Apr, 2012 | Pubmed ID: 22577343 The Fbx4 Tumor Suppressor Regulates Cyclin D1 Accumulation and Prevents Neoplastic Transformation Molecular and Cellular Biology. Nov, 2011 | Pubmed ID: 21911473 Biomechanical Remodeling of the Microenvironment by Stromal Caveolin-1 Favors Tumor Invasion and Metastasis Cell. Jul, 2011 | Pubmed ID: 21729786 Influence of Affinity and Antigen Internalization on the Uptake and Penetration of Anti-HER2 Antibodies in Solid Tumors Cancer Research. Mar, 2011 | Pubmed ID: 21406401 Estrogen and Cytochrome P450 1B1 Contribute to Both Early- and Late-stage Head and Neck Carcinogenesis Cancer Prevention Research (Philadelphia, Pa.). Jan, 2011 | Pubmed ID: 21205741 Proprotein Convertase Inhibition Results in Decreased Skin Cell Proliferation, Tumorigenesis, and Metastasis Neoplasia (New York, N.Y.). Jul, 2010 | Pubmed ID: 20651981 VILIP-1 Expression in Vivo Results in Decreased Mouse Skin Keratinocyte Proliferation and Tumor Development PloS One. Apr, 2010 | Pubmed ID: 20419170 Hypoxia Activates the Cyclooxygenase-2-prostaglandin E Synthase Axis Carcinogenesis. Mar, 2010 | Pubmed ID: 20042640 TRAIL-R Deficiency in Mice Promotes Susceptibility to Chronic Inflammation and Tumorigenesis The Journal of Clinical Investigation. Jan, 2008 | Pubmed ID: 18079962 Nuclear Accumulation of Cyclin D1 During S Phase Inhibits Cul4-dependent Cdt1 Proteolysis and Triggers P53-dependent DNA Rereplication Genes & Development. Nov, 2007 | Pubmed ID: 18006686 Increased Expression of the Pro-protein Convertase Furin Predicts Decreased Survival in Ovarian Cancer Cellular Oncology : the Official Journal of the International Society for Cellular Oncology. 2007 | Pubmed ID: 17641413 IGFBP-3 Regulates Esophageal Tumor Growth Through IGF-dependent and Independent Mechanisms Cancer Biology & Therapy. Apr, 2007 | Pubmed ID: 17457048 Inhibition of Proprotein Convertases: Approaches to Block Squamous Carcinoma Development and Progression Molecular Carcinogenesis. Aug, 2007 | Pubmed ID: 17440928 Phosphorylation-dependent Ubiquitination of Cyclin D1 by the SCF(FBX4-alphaB Crystallin) Complex Molecular Cell. Nov, 2006 | Pubmed ID: 17081987 Proprotein Convertases: "master Switches" in the Regulation of Tumor Growth and Progression Molecular Carcinogenesis. Nov, 2005 | Pubmed ID: 16167351 PACE4 Expression in Mouse Basal Keratinocytes Results in Basement Membrane Disruption and Acceleration of Tumor Progression Cancer Research. Aug, 2005 | Pubmed ID: 16103082 Stroma-derived Three-dimensional Matrices Are Necessary and Sufficient to Promote Desmoplastic Differentiation of Normal Fibroblasts The American Journal of Pathology. Aug, 2005 | Pubmed ID: 16049333 Human Carcinoma Cell Growth and Invasiveness is Impaired by the Propeptide of the Ubiquitous Proprotein Convertase Furin Cancer Research. May, 2005 | Pubmed ID: 15899807 Linking Transcriptional Elongation and Messenger RNA Export to Metastatic Breast Cancers Cancer Research. Apr, 2005 | Pubmed ID: 15833825 Visinin-like Protein-1 is a Potent Inhibitor of Cell Adhesion and Migration in Squamous Carcinoma Cells Oncogene. Mar, 2005 | Pubmed ID: 15735716 Frequent Loss of WWOX Expression in Breast Cancer: Correlation with Estrogen Receptor Status Breast Cancer Research and Treatment. Jan, 2005 | Pubmed ID: 15692750 A Single Treatment of Yttrium-90-labeled CHX-A"-C6.5 Diabody Inhibits the Growth of Established Human Tumor Xenografts in Immunodeficient Mice Cancer Research. Sep, 2004 | Pubmed ID: 15342405 Overexpression of the Calcium Sensor Visinin-like Protein-1 Leads to a CAMP-mediated Decrease of in Vivo and in Vitro Growth and Invasiveness of Squamous Cell Carcinoma Cells Cancer Research. Aug, 2003 | Pubmed ID: 12941826 Stromelysin-1/matrix Metalloproteinase-3 (MMP-3) Expression Accounts for Invasive Properties of Human Astrocytoma Cell Lines International Journal of Cancer. Sep, 2003 | Pubmed ID: 12866026 Overexpression of Cyclin D2 is Associated with Increased in Vivo Invasiveness of Human Squamous Carcinoma Cells Molecular Carcinogenesis. Jul, 2002 | Pubmed ID: 12112307 Malignant Conversion of Non-tumorigenic Murine Skin Keratinocytes Overexpressing PACE4 Carcinogenesis. Apr, 2002 | Pubmed ID: 11960907 Furin Inhibition Results in Absent or Decreased Invasiveness and Tumorigenicity of Human Cancer Cells Proceedings of the National Academy of Sciences of the United States of America. Aug, 2001 | Pubmed ID: 11517338 Onset of Natural Killer Cell Lymphomas in Transgenic Mice Carrying a Truncated HMGI-C Gene by the Chronic Stimulation of the IL-2 and IL-15 Pathway Proceedings of the National Academy of Sciences of the United States of America. Jul, 2001 | Pubmed ID: 11427729 Cell Cycle-regulated Processing of HEF1 to Multiple Protein Forms Differentially Targeted to Multiple Subcellular Compartments Molecular and Cellular Biology. Jun, 1998 | Pubmed ID: 9584194 Invasive and Metastatic Potential of a V-Ha-ras-transformed Human Bronchial Epithelial Cell Line Journal of the National Cancer Institute. Apr, 1989 | Pubmed ID: 2539488 Resistance to Serum-induced Terminal Differentiation in Normal Human Tracheobronchial Epithelial Cells After in Vivo Exposure to 7,12-dimethylbenz[a]anthracene Japanese Journal of Cancer Research : Gann. Jun, 1988 | Pubmed ID: 3137200 Modellering van oraal-oesofageaal plaveiselcelcarcinoom in 3D-organoïden Samuel Flashner*1, Cecilia Martin*1,2, Norihiro Matsuura1, Masataka Shimonosono1, Yasuto Tomita1, Masaki Morimoto1, Ogoegbunam Okolo1, Victoria X. Yu1,3, Anuraag S. Parikh1,3, Andres J. P. Klein-Szanto4, Kelley Yan1,2, Joel T. Gabre1,5, Chao Lu1,6, Fatemeh Momen-Heravi1,7, Anil K. Rustgi1,5, Hiroshi Nakagawa1,2,5 1Herbert Irving Comprehensive Cancer Center, Columbia University, 2Organoid and Cell Culture Core, Columbia University Digestive and Liver Diseases Research Center, Columbia University, 3Department of Otolaryngology, Head and Neck Surgery, Columbia University, 4Histopathology Facility, Fox Chase Cancer Center, 5Division of Digestive and Liver Diseases, Department of Medicine, Columbia University, 6Department of Genetics and Development, Columbia University, 7Section of Oral, Diagnostic and Rehabilitation Sciences, College of Dental Medicine, Columbia University JoVE 64676 Ricerca sul cancro
Modellering van oraal-oesofageaal plaveiselcelcarcinoom in 3D-organoïden Samuel Flashner*1, Cecilia Martin*1,2, Norihiro Matsuura1, Masataka Shimonosono1, Yasuto Tomita1, Masaki Morimoto1, Ogoegbunam Okolo1, Victoria X. Yu1,3, Anuraag S. Parikh1,3, Andres J. P. Klein-Szanto4, Kelley Yan1,2, Joel T. Gabre1,5, Chao Lu1,6, Fatemeh Momen-Heravi1,7, Anil K. Rustgi1,5, Hiroshi Nakagawa1,2,5 1Herbert Irving Comprehensive Cancer Center, Columbia University, 2Organoid and Cell Culture Core, Columbia University Digestive and Liver Diseases Research Center, Columbia University, 3Department of Otolaryngology, Head and Neck Surgery, Columbia University, 4Histopathology Facility, Fox Chase Cancer Center, 5Division of Digestive and Liver Diseases, Department of Medicine, Columbia University, 6Department of Genetics and Development, Columbia University, 7Section of Oral, Diagnostic and Rehabilitation Sciences, College of Dental Medicine, Columbia University JoVE 64676 Ricerca sul cancro