Anne Osbourn John Innes Centre Biography Publications Institution JoVE Articles Anne Osbourn has not added a biography. If you are Anne Osbourn and would like to personalize this page please email our Author Liaison for assistance. Publications Sea Cucumber Genome Provides Insights into Saponin Biosynthesis and Aestivation Regulation Cell Discovery. 2018 | Pubmed ID: 29951224 Multigenome Analysis Implicates Miniature Inverted-repeat Transposable Elements (MITEs) in Metabolic Diversification in Eudicots Proceedings of the National Academy of Sciences of the United States of America. Jul, 2018 | Pubmed ID: 29941591 Engineering Terpenoid Production Through Transient Expression in Nicotiana Benthamiana Plant Cell Reports. May, 2018 | Pubmed ID: 29786761 Identification of Key Amino Acid Residues Determining Product Specificity of 2,3-oxidosqualene Cyclase in Oryza Species The New Phytologist. May, 2018 | Pubmed ID: 29528490 Triterpene Messages from the EU-FP7 Project TriForC Trends in Plant Science. Apr, 2018 | Pubmed ID: 29483042 Diverged Plant Terpene Synthases Reroute the Carbocation Cyclization Path Towards the Formation of Unprecedented 6/11/5 and 6/6/7/5 Sesterterpene Scaffolds Angewandte Chemie (International Ed. in English). Jan, 2018 | Pubmed ID: 29194888 Can Human Experts Predict Solubility Better Than Computers? Journal of Cheminformatics. Dec, 2017 | Pubmed ID: 29238891 Painting with Betalains Nature Plants. Nov, 2017 | Pubmed ID: 29116231 A Translational Synthetic Biology Platform for Rapid Access to Gram-scale Quantities of Novel Drug-like Molecules Metabolic Engineering. 07, 2017 | Pubmed ID: 28687337 Unearthing a Sesterterpene Biosynthetic Repertoire in the Brassicaceae Through Genome Mining Reveals Convergent Evolution Proceedings of the National Academy of Sciences of the United States of America. 07, 2017 | Pubmed ID: 28673978 Harnessing Plant Metabolic Diversity Current Opinion in Chemical Biology. Oct, 2017 | Pubmed ID: 28527344 PlantiSMASH: Automated Identification, Annotation and Expression Analysis of Plant Biosynthetic Gene Clusters Nucleic Acids Research. Jul, 2017 | Pubmed ID: 28453650 Convergence and Divergence of Bitterness Biosynthesis and Regulation in Cucurbitaceae Nature Plants. 11, 2016 | Pubmed ID: 27892922 A Conserved Amino Acid Residue Critical for Product and Substrate Specificity in Plant Triterpene Synthases Proceedings of the National Academy of Sciences of the United States of America. 07, 2016 | Pubmed ID: 27412861 Computational Genomic Identification and Functional Reconstitution of Plant Natural Product Biosynthetic Pathways Natural Product Reports. Aug, 2016 | Pubmed ID: 27321668 Plant Metabolic Clusters - from Genetics to Genomics The New Phytologist. 08, 2016 | Pubmed ID: 27112429 Delineation of Metabolic Gene Clusters in Plant Genomes by Chromatin Signatures Nucleic Acids Research. Mar, 2016 | Pubmed ID: 26895889 Editorial Overview: Plant Biotechnology Current Opinion in Biotechnology. Feb, 2016 | Pubmed ID: 26730719 Identification and Characterization of the Iridoid Synthase Involved in Oleuropein Biosynthesis in Olive (Olea Europaea) Fruits The Journal of Biological Chemistry. Mar, 2016 | Pubmed ID: 26709230 Minimum Information About a Biosynthetic Gene Cluster Nature Chemical Biology. Sep, 2015 | Pubmed ID: 26284661 Standards for Plant Synthetic Biology: a Common Syntax for Exchange of DNA Parts The New Phytologist. Oct, 2015 | Pubmed ID: 26171760 MYB Transcription Factors As Regulators of Phenylpropanoid Metabolism in Plants Molecular Plant. May, 2015 | Pubmed ID: 25840349 OSC2 and CYP716A14v2 Catalyze the Biosynthesis of Triterpenoids for the Cuticle of Aerial Organs of Artemisia Annua The Plant Cell. Jan, 2015 | Pubmed ID: 25576188 Temporal Transcriptome Changes Induced by Methyl Jasmonate in Salvia Sclarea Gene. Mar, 2015 | Pubmed ID: 25536164 Investigation of Terpene Diversification Across Multiple Sequenced Plant Genomes Proceedings of the National Academy of Sciences of the United States of America. Jan, 2015 | Pubmed ID: 25502595 Regulation of Metabolic Gene Clusters in Arabidopsis Thaliana The New Phytologist. Jan, 2015 | Pubmed ID: 25417931 Metabolic and Functional Diversity of Saponins, Biosynthetic Intermediates and Semi-synthetic Derivatives Critical Reviews in Biochemistry and Molecular Biology. Nov-Dec, 2014 | Pubmed ID: 25286183 Key Applications of Plant Metabolic Engineering PLoS Biology. Jun, 2014 | Pubmed ID: 24915445 Investigation of Triterpene Synthesis and Regulation in Oats Reveals a Role for β-amyrin in Determining Root Epidermal Cell Patterning Proceedings of the National Academy of Sciences of the United States of America. Jun, 2014 | Pubmed ID: 24912185 Gene Clustering in Plant Specialized Metabolism Current Opinion in Biotechnology. Apr, 2014 | Pubmed ID: 24679264 Triterpene Biosynthesis in Plants Annual Review of Plant Biology. 2014 | Pubmed ID: 24498976 Rapid Metabolic Pathway Assembly and Modification Using Serine Integrase Site-specific Recombination Nucleic Acids Research. Feb, 2014 | Pubmed ID: 24225316 Biochemical Analysis of a Multifunctional Cytochrome P450 (CYP51) Enzyme Required for Synthesis of Antimicrobial Triterpenes in Plants Proceedings of the National Academy of Sciences of the United States of America. Aug, 2013 | Pubmed ID: 23940321 Comparative Metatranscriptomics Reveals Kingdom Level Changes in the Rhizosphere Microbiome of Plants The ISME Journal. Dec, 2013 | Pubmed ID: 23864127 A One-pot Enzymatic Approach to the O-fluoroglucoside of N-methylanthranilate Bioorganic & Medicinal Chemistry. Aug, 2013 | Pubmed ID: 23806835 Modularity of Plant Metabolic Gene Clusters: a Trio of Linked Genes That Are Collectively Required for Acylation of Triterpenes in Oat The Plant Cell. Mar, 2013 | Pubmed ID: 23532069 Glycosyltransferases from Oat (Avena) Implicated in the Acylation of Avenacins The Journal of Biological Chemistry. Feb, 2013 | Pubmed ID: 23258535 Finding and Analyzing Plant Metabolic Gene Clusters Methods in Enzymology. 2012 | Pubmed ID: 23084936 Synthetic Biology. 4th New Phytologist Workshop, Bristol, UK, June 2012 The New Phytologist. Nov, 2012 | Pubmed ID: 23043589 Order in the Playground: Formation of Plant Gene Clusters in Dynamic Chromosomal Regions Mobile Genetic Elements. Jan, 2012 | Pubmed ID: 22754752 Formation of Plant Metabolic Gene Clusters Within Dynamic Chromosomal Regions Proceedings of the National Academy of Sciences of the United States of America. Sep, 2011 | Pubmed ID: 21876149 The Saponins: Polar Isoprenoids with Important and Diverse Biological Activities Natural Product Reports. Jul, 2011 | Pubmed ID: 21584304 Investigation of the Potential for Triterpene Synthesis in Rice Through Genome Mining and Metabolic Engineering The New Phytologist. Jul, 2011 | Pubmed ID: 21501172 From Hormones to Secondary Metabolism: the Emergence of Metabolic Gene Clusters in Plants The Plant Journal : for Cell and Molecular Biology. Apr, 2011 | Pubmed ID: 21443624 Gene Clusters for Secondary Metabolic Pathways: an Emerging Theme in Plant Biology Plant Physiology. Oct, 2010 | Pubmed ID: 20921179 Secondary Metabolic Gene Clusters: Evolutionary Toolkits for Chemical Innovation Trends in Genetics : TIG. Oct, 2010 | Pubmed ID: 20739089 Common Genetic Pathways Regulate Organ-specific Infection-related Development in the Rice Blast Fungus The Plant Cell. Mar, 2010 | Pubmed ID: 20348434 Evolution of Serine Carboxypeptidase-like Acyltransferases in the Monocots Plant Signaling & Behavior. Feb, 2010 | Pubmed ID: 20173416 Cell Type-specific Chromatin Decondensation of a Metabolic Gene Cluster in Oats The Plant Cell. Dec, 2009 | Pubmed ID: 20040536 A Serine Carboxypeptidase-like Acyltransferase is Required for Synthesis of Antimicrobial Compounds and Disease Resistance in Oats The Plant Cell. Aug, 2009 | Pubmed ID: 19684243 Operons Cellular and Molecular Life Sciences : CMLS. Dec, 2009 | Pubmed ID: 19662496 SAW: Breaking Down Barriers Between Art and Science PLoS Biology. Aug, 2008 | Pubmed ID: 18752351 Metabolic Diversification--independent Assembly of Operon-like Gene Clusters in Different Plants Science (New York, N.Y.). Apr, 2008 | Pubmed ID: 18356490 Sad3 and Sad4 Are Required for Saponin Biosynthesis and Root Development in Oat The Plant Cell. Jan, 2008 | Pubmed ID: 18203919 A Different Function for a Member of an Ancient and Highly Conserved Cytochrome P450 Family: from Essential Sterols to Plant Defense Proceedings of the National Academy of Sciences of the United States of America. Dec, 2006 | Pubmed ID: 17124172 First Encounters--deployment of Defence-related Natural Products by Plants The New Phytologist. 2006 | Pubmed ID: 16995908 Dual Effects of Plant Steroidal Alkaloids on Saccharomyces Cerevisiae Antimicrobial Agents and Chemotherapy. Aug, 2006 | Pubmed ID: 16870766 The Poetry of Science Nature Reviews. Microbiology. 01, 2006 | Pubmed ID: 16357863 Comparative Transcriptomics of Rice Reveals an Ancient Pattern of Response to Microbial Colonization Proceedings of the National Academy of Sciences of the United States of America. May, 2005 | Pubmed ID: 15905328 Unravelling Triterpene Glycoside Synthesis in Plants: Phytochemistry and Functional Genomics Join Forces Planta. Feb, 2005 | Pubmed ID: 15703926 2003 Asilomar Meeting Report Fungal Genetics and Biology : FG & B. Feb, 2004 | Pubmed ID: 14732257 Molecular Cloning and Characterization of Triterpene Synthases from Medicago Truncatula and Lotus Japonicus Plant Molecular Biology. Mar, 2003 | Pubmed ID: 12683345 Saponins in Cereals Phytochemistry. Jan, 2003 | Pubmed ID: 12475612 Biosynthesis of Triterpenoid Saponins in Plants Advances in Biochemical Engineering/biotechnology. 2002 | Pubmed ID: 11783842 Tox-boxes, Fungal Secondary Metabolites, and Plant Disease Proceedings of the National Academy of Sciences of the United States of America. Dec, 2001 | Pubmed ID: 11734635 L-RCA (ligation-rolling Circle Amplification): a General Method for Genotyping of Single Nucleotide Polymorphisms (SNPs) Nucleic Acids Research. Nov, 2001 | Pubmed ID: 11713336 Fungal Resistance to Plant Antibiotics As a Mechanism of Pathogenesis Microbiology and Molecular Biology Reviews : MMBR. Sep, 1999 | Pubmed ID: 10477313 Isolation, Characterization, and Avenacin Sensitivity of a Diverse Collection of Cereal-root-colonizing Fungi Applied and Environmental Microbiology. Aug, 1999 | Pubmed ID: 10427021 Forbigående uttrykk i Nicotiana Benthamiana forlater Triterpene produksjon i skytevåpen skala Michael J. Stephenson1, James Reed1, Bastiaan Brouwer1, Anne Osbourn1 1John Innes Centre JoVE 58169 Biochimica
Forbigående uttrykk i Nicotiana Benthamiana forlater Triterpene produksjon i skytevåpen skala Michael J. Stephenson1, James Reed1, Bastiaan Brouwer1, Anne Osbourn1 1John Innes Centre JoVE 58169 Biochimica