Anthony J. Hickey Technology Advancement and Commercialization RTI International Biography Publications Institution JoVE Articles Anthony J. Hickey has not added a biography. If you are Anthony J. Hickey and would like to personalize this page please email our Author Liaison for assistance. Publications Pharmacokinetic Considerations for Optimizing Inhaled Spray-Dried Pyrazinoic Acid Formulations Molecular Pharmaceutics. Aug, 2023 | Pubmed ID: 37590399 Development of a Minimalistic Physiologically Based Pharmacokinetic (mPBPK) Model for the Preclinical Development of Spectinamide Antibiotics Pharmaceutics. Jun, 2023 | Pubmed ID: 37376207 Preparation Strategies of the Anti-Mycobacterial Drug Bedaquiline for Intrapulmonary Routes of Administration Pharmaceuticals (Basel, Switzerland). May, 2023 | Pubmed ID: 37242512 Characterization of Spectinamide 1599 Efficacy Against Different Mycobacterial Phenotypes Tuberculosis (Edinburgh, Scotland). May, 2023 | Pubmed ID: 37120915 Spray Dried Tigecycline Dry Powder Aerosols for the Treatment of Nontuberculous Mycobacterial Pulmonary Infections Tuberculosis (Edinburgh, Scotland). Mar, 2023 | Pubmed ID: 36716525 Stable Nebulization and Muco-trapping Properties of Regdanvimab/IN-006 Support Its Development As a Potent, Dose-saving Inhaled Therapy for COVID-19 Bioengineering & Translational Medicine. Aug, 2022 | Pubmed ID: 36248234 Multiple Approaches to Repurposing Drugs for Neuroblastoma Bioorganic & Medicinal Chemistry. Nov, 2022 | Pubmed ID: 36208544 Optimization and Scale Up of Spray Dried CPZEN-45 Aerosol Powders for Inhaled Tuberculosis Treatment Pharmaceutical Research. Dec, 2022 | Pubmed ID: 36114362 Efficacy of Inhaled CPZEN-45 in Treating Tuberculosis in the Guinea Pig Tuberculosis (Edinburgh, Scotland). Jul, 2022 | Pubmed ID: 35588549 Nanoformulated Remdesivir with Extremely Low Content of Poly(2-oxazoline)-Based Stabilizer for Aerosol Treatment of COVID-19 Macromolecular Bioscience. Aug, 2022 | Pubmed ID: 35526106 COVID-19 Symptoms Are Reduced by Targeted Hydration of the Nose, Larynx and Trachea Scientific Reports. Mar, 2022 | Pubmed ID: 35351914 Inhaled Antibodies: Quality and Performance Considerations Human Vaccines & Immunotherapeutics. Apr, 2022 | Pubmed ID: 34191682 In Vitro-in Vivo Correlation of Pharmaceutical Aerosols Advanced Drug Delivery Reviews. Dec, 2021 | Pubmed ID: 34710531 Preclinical Evaluation of Inhalational Spectinamide-1599 Therapy Against Tuberculosis ACS Infectious Diseases. Oct, 2021 | Pubmed ID: 34546724 A Technology Evaluation of CVT-301 (Inbrija): an Inhalable Therapy for Treatment of Parkinson's Disease Expert Opinion on Drug Delivery. Nov, 2021 | Pubmed ID: 34311641 Microfluidic and Organ-on-a-Chip Approaches to Investigate Cellular and Microenvironmental Contributions to Cardiovascular Function and Pathology Frontiers in Bioengineering and Biotechnology. 2021 | Pubmed ID: 33614613 User-life of ICS/LABA Inhaler Devices Should Be Considered when Prescribed As Relievers The European Respiratory Journal. Jan, 2021 | Pubmed ID: 33446577 A Mechanism-based Pharmacokinetic Model of Remdesivir Leveraging Interspecies Scaling to Simulate COVID-19 Treatment in Humans CPT: Pharmacometrics & Systems Pharmacology. 02, 2021 | Pubmed ID: 33296558 Designing Inhalable Metal Organic Frameworks for Pulmonary Tuberculosis Treatment and Theragnostics Via Spray Drying Chemical Communications (Cambridge, England). Nov, 2020 | Pubmed ID: 33025961 Synergistic Drug Combinations and Machine Learning for Drug Repurposing in Chordoma Scientific Reports. Jul, 2020 | Pubmed ID: 32737414 Emerging Trends in Inhaled Drug Delivery Advanced Drug Delivery Reviews. 2020 | Pubmed ID: 32663488 Why Wait? The Case for Treating Tuberculosis with Inhaled Drugs Pharmaceutical Research. Oct, 2019 | Pubmed ID: 31650321 Sterilization of Mycobacterium Tuberculosis Infected Samples Using Methanol Preserves Anti-tuberculosis Drugs for Subsequent Pharmacological Testing Studies Tuberculosis (Edinburgh, Scotland). Jul, 2019 | Pubmed ID: 31378268 Development and Characterization of a Dry Powder Formulation for Anti-Tuberculosis Drug Spectinamide 1599 Pharmaceutical Research. Jul, 2019 | Pubmed ID: 31321552 A Spray-Dried Combination of Capreomycin and CPZEN-45 for Inhaled Tuberculosis Therapy Journal of Pharmaceutical Sciences. Oct, 2019 | Pubmed ID: 31152746 Exploiting Machine Learning for End-to-end Drug Discovery and Development Nature Materials. May, 2019 | Pubmed ID: 31000803 Efficacy of Pyrazinoic Acid Dry Powder Aerosols in Resolving Necrotic and Non-necrotic Granulomas in a Guinea Pig Model of Tuberculosis PloS One. 2018 | Pubmed ID: 30261007 Pharmacokinetics and Pharmacodynamics of High Doses of Inhaled Dry Powder Drugs International Journal of Pharmaceutics. Oct, 2018 | Pubmed ID: 30077761 Effects of Formulation Variables on Lung Dosimetry of Albuterol Sulfate Suspension and Beclomethasone Dipropionate Solution Metered Dose Inhalers AAPS PharmSciTech. Jul, 2018 | Pubmed ID: 29858973 Co-suspension Delivery Technology in Pressurized Metered-dose Inhalers for Multi-drug Dosing in the Treatment of Respiratory Diseases Respiratory Medicine. Jan, 2018 | Pubmed ID: 29413503 Density and Shape Factor Terms in Stokes' Equation for Aerodynamic Behavior of Aerosols Journal of Pharmaceutical Sciences. Mar, 2018 | Pubmed ID: 29154770 Reproducibility, Sharing and Progress in Nanomaterial Databases Nature Nanotechnology. Dec, 2017 | Pubmed ID: 29209007 Influence of Formulation Factors on the Aerosol Performance of Suspension and Solution Metered Dose Inhalers: A Systematic Approach The AAPS Journal. Sep, 2017 | Pubmed ID: 28593514 Nanomaterial Drug Products: Manufacturing and Analytical Perspectives The AAPS Journal. Jan, 2017 | Pubmed ID: 27822601 Systems Biology for Organotypic Cell Cultures ALTEX. Nov, 2016 | Pubmed ID: 27846345 Inhaled Pyrazinoic Acid Esters for the Treatment of Tuberculosis Pharmaceutical Research. Oct, 2016 | Pubmed ID: 27351427 A Dry Powder Combination of Pyrazinoic Acid and Its N-propyl Ester for Aerosol Administration to Animals International Journal of Pharmaceutics. Dec, 2016 | Pubmed ID: 27130363 Real-Time Investigation of Tuberculosis Transmission: Developing the Respiratory Aerosol Sampling Chamber (RASC) PloS One. 2016 | Pubmed ID: 26807816 Inhaled Drug Treatment for Tuberculosis: Past Progress and Future Prospects Journal of Controlled Release : Official Journal of the Controlled Release Society. Oct, 2016 | Pubmed ID: 26596254 In Vitro Dry Powder Inhaler Formulation Performance Considerations Journal of Controlled Release : Official Journal of the Controlled Release Society. Feb, 2015 | Pubmed ID: 25497311 Targeting Inhaled Therapy Beyond the Lungs Respiration; International Review of Thoracic Diseases. 2014 | Pubmed ID: 25277464 The Role of Particle Physico-chemical Properties in Pulmonary Drug Delivery for Tuberculosis Therapy Journal of Microencapsulation. 2014 | Pubmed ID: 25090595 Scale of Health: Indices of Safety and Efficacy in the Evolving Environment of Large Biological Datasets Pharmaceutical Research. Sep, 2014 | Pubmed ID: 24919930 Controlled Delivery of Inhaled Therapeutic Agents Journal of Controlled Release : Official Journal of the Controlled Release Society. Sep, 2014 | Pubmed ID: 24907604 Lipid-based Carriers for Pulmonary Products: Preclinical Development and Case Studies in Humans Advanced Drug Delivery Reviews. Aug, 2014 | Pubmed ID: 24819218 New Mechanisms to Explain the Effects of Added Lactose Fines on the Dispersion Performance of Adhesive Mixtures for Inhalation PloS One. 2014 | Pubmed ID: 24489969 Back to the Future: Inhaled Drug Products Journal of Pharmaceutical Sciences. Apr, 2013 | Pubmed ID: 23381932 Developing a Disposable Dosator for Preclinical Testing of Dry Powder Inhalers in Small Animal Models (Video) | JoVE Sara E. Maloney1, Ian E. Stewart1, Jeffrey B. Mecham1, Mercedes Gonzalez-Juarrero2, Bernd Meibohm3, Anthony J. Hickey1 1Technology Advancement and Commercialization, RTI International, 2Mycobacteria Research Laboratories, Department of Microbiology, Immunology, and Pathology, Colorado State University, 3Department of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee Health Science Center JoVE 65756 Medicina Disposable Dosators for Pulmonary Insufflation of Therapeutic Agents to Small Animals Phillip G. Durham1, Shumaila N. Hanif2, Lucia Garcia Contreras2, Ellen F. Young3, Miriam S. Braunstein3, Anthony J. Hickey1 1RTI International, 2Oklahoma University Health Science Center, 3University of North Carolina at Chapel Hill JoVE 55356 Medicina
Developing a Disposable Dosator for Preclinical Testing of Dry Powder Inhalers in Small Animal Models (Video) | JoVE Sara E. Maloney1, Ian E. Stewart1, Jeffrey B. Mecham1, Mercedes Gonzalez-Juarrero2, Bernd Meibohm3, Anthony J. Hickey1 1Technology Advancement and Commercialization, RTI International, 2Mycobacteria Research Laboratories, Department of Microbiology, Immunology, and Pathology, Colorado State University, 3Department of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee Health Science Center JoVE 65756 Medicina
Disposable Dosators for Pulmonary Insufflation of Therapeutic Agents to Small Animals Phillip G. Durham1, Shumaila N. Hanif2, Lucia Garcia Contreras2, Ellen F. Young3, Miriam S. Braunstein3, Anthony J. Hickey1 1RTI International, 2Oklahoma University Health Science Center, 3University of North Carolina at Chapel Hill JoVE 55356 Medicina