Anton Wellstein Lombardi Comprehensive Cancer Center Georgetown University Medical Center Biography Publications Institution JoVE Articles Anton Wellstein has not added a biography. If you are Anton Wellstein and would like to personalize this page please email our Author Liaison for assistance. Publications Distinct Response of Circulating MicroRNAs to the Treatment of Pancreatic Cancer Xenografts with FGFR and ALK Kinase Inhibitors Cancers. Mar, 2022 | Pubmed ID: 35326668 An AIB1 Isoform Alters Enhancer Access and Enables Progression of Early-Stage Triple-Negative Breast Cancer Cancer Research. 08, 2021 | Pubmed ID: 34135000 Cadherin 11 Promotes Immunosuppression and Extracellular Matrix Deposition to Support Growth of Pancreatic Tumors and Resistance to Gemcitabine in Mice Gastroenterology. 03, 2021 | Pubmed ID: 33307028 Loss of ANCO1 Repression at AIB1/YAP Targets Drives Breast Cancer Progression EMBO Reports. Jan, 2020 | Pubmed ID: 31788936 Short- and Long-Term Effects of CDK4/6 Inhibition on Early-Stage Breast Cancer Molecular Cancer Therapeutics. 12, 2019 | Pubmed ID: 31451564 Single-Molecule Real-Time (SMRT) Full-Length RNA-Sequencing Reveals Novel and Distinct MRNA Isoforms in Human Bone Marrow Cell Subpopulations Genes. 03, 2019 | Pubmed ID: 30934798 Fenofibrate Improves Vascular Endothelial Function and Contractility in Diabetic Mice Redox Biology. 01, 2019 | Pubmed ID: 30296701 Reprint Of: Circulating Cell-free DNA Mutation Patterns in Early and Late Stage Colon and Pancreatic Cancer Cancer Genetics. 12, 2018 | Pubmed ID: 30447903 Fibroblast Growth Factor Binding Protein 3 (FGFBP3) Impacts Carbohydrate and Lipid Metabolism Scientific Reports. 10, 2018 | Pubmed ID: 30374109 High Salt Enhances Reactive Oxygen Species and Angiotensin II Contractions of Glomerular Afferent Arterioles From Mice With Reduced Renal Mass Hypertension (Dallas, Tex. : 1979). 11, 2018 | Pubmed ID: 30354808 Left Ventricular Dysfunction in Cancer Treatment: Is It Relevant? JACC. Heart Failure. 02, 2018 | Pubmed ID: 29413379 The PPARγ Agonist Efatutazone Delays Invasive Progression and Induces Differentiation of Ductal Carcinoma in Situ Breast Cancer Research and Treatment. May, 2018 | Pubmed ID: 29350308 NRF2 Prevents Hypertension, Increased ADMA, Microvascular Oxidative Stress, and Dysfunction in Mice with Two Weeks of ANG II Infusion American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 03, 2018 | Pubmed ID: 29167164 Blood Pressure Control by a Secreted FGFBP1 (Fibroblast Growth Factor-Binding Protein) Hypertension (Dallas, Tex. : 1979). 01, 2018 | Pubmed ID: 29158353 The Role of Fibroblast Growth Factor-Binding Protein 1 in Skin Carcinogenesis and Inflammation The Journal of Investigative Dermatology. 01, 2018 | Pubmed ID: 28864076 Circulating Cell-free DNA Mutation Patterns in Early and Late Stage Colon and Pancreatic Cancer Cancer Genetics. Dec, 2017 | Pubmed ID: 29153095 Circulating MicroRNAs in Patients with Hormone Receptor-positive, Metastatic Breast Cancer Treated with Dovitinib Clinical and Translational Medicine. Oct, 2017 | Pubmed ID: 28980224 Midkine and Pleiotrophin Concentrations in Needle Biopsies of Breast and Lung Masses Cancer Biomarkers : Section A of Disease Markers. Sep, 2017 | Pubmed ID: 28946562 Conditional Cell Reprogramming Involves Non-canonical β-catenin Activation and MTOR-mediated Inactivation of Akt PloS One. 2017 | Pubmed ID: 28700668 Superoxide and Hydrogen Peroxide Counterregulate Myogenic Contractions in Renal Afferent Arterioles from a Mouse Model of Chronic Kidney Disease Kidney International. 09, 2017 | Pubmed ID: 28396118 Keratin-associated Protein 5-5 Controls Cytoskeletal Function and Cancer Cell Vascular Invasion Oncogene. 02, 2017 | Pubmed ID: 27375028 Circulating Biomarkers to Monitor Cancer Progression and Treatment Computational and Structural Biotechnology Journal. 2016 | Pubmed ID: 27358717 Midkine and Pleiotrophin Concentrations in Amniotic Fluid in Healthy and Complicated Pregnancies PloS One. 2016 | Pubmed ID: 27089523 Differential Effects of Superoxide and Hydrogen Peroxide on Myogenic Signaling, Membrane Potential, and Contractions of Mouse Renal Afferent Arterioles American Journal of Physiology. Renal Physiology. Jun, 2016 | Pubmed ID: 27053691 Circulating MicroRNA Profile Predicts Disease Progression in Patients Receiving Second-line Treatment of Lapatinib and Capecitabine for Metastatic Pancreatic Cancer Oncology Letters. Mar, 2016 | Pubmed ID: 26998056 Increased Pleiotrophin Concentrations in Papillary Thyroid Cancer PloS One. 2016 | Pubmed ID: 26914549 Cell Density Regulates Cancer Metastasis Via the Hippo Pathway Future Oncology (London, England). Nov, 2015 | Pubmed ID: 26561730 Circulating DNA and Micro-RNA in Patients with Pancreatic Cancer Pancreatic Disorders & Therapy. Jun, 2015 | Pubmed ID: 26161297 Distinct Serum Metabolomics Profiles Associated with Malignant Progression in the KrasG12D Mouse Model of Pancreatic Ductal Adenocarcinoma BMC Genomics. 2015 | Pubmed ID: 25923219 Cell Growth Density Modulates Cancer Cell Vascular Invasion Via Hippo Pathway Activity and CXCR2 Signaling Oncogene. Nov, 2015 | Pubmed ID: 25772246 Thromboxane Prostanoid Receptors Enhance Contractions, Endothelin-1, and Oxidative Stress in Microvessels from Mice with Chronic Kidney Disease Hypertension. May, 2015 | Pubmed ID: 25733239 Utility of a Human-mouse Xenograft Model and in Vivo Near-infrared Fluorescent Imaging for Studying Wound Healing International Wound Journal. Dec, 2015 | Pubmed ID: 24373153 Expression of a Secreted Fibroblast Growth Factor Binding Protein-1 (FGFBP1) in Angioproliferative Kaposi Sarcoma Journal of AIDS & Clinical Research. Jun, 2014 | Pubmed ID: 25429350 Conditionally Reprogrammed Normal and Transformed Mouse Mammary Epithelial Cells Display a Progenitor-cell-like Phenotype PloS One. 2014 | Pubmed ID: 24831228 Downstream of Mutant KRAS, the Transcription Regulator YAP is Essential for Neoplastic Progression to Pancreatic Ductal Adenocarcinoma Science Signaling. May, 2014 | Pubmed ID: 24803537 SLC25A1, or CIC, is a Novel Transcriptional Target of Mutant P53 and a Negative Tumor Prognostic Marker Oncotarget. Mar, 2014 | Pubmed ID: 24681808 Regulation of HER2 Oncogene Transcription by a Multifunctional Coactivator/corepressor Complex Molecular Endocrinology (Baltimore, Md.). Jun, 2014 | Pubmed ID: 24678732 Recurrence of Early Stage Colon Cancer Predicted by Expression Pattern of Circulating MicroRNAs PloS One. 2014 | Pubmed ID: 24400111 Late Failure of a Split-thickness Skin Graft in the Setting of Homozygous Factor V Leiden Mutation: a Case Report and Correlative Animal Model from the Wound Etiology and Healing (WE-HEAL) Study International Wound Journal. Sep, 2013 | Pubmed ID: 24028566 Transcriptional Repression of AIB1 by FoxG1 Leads to Apoptosis in Breast Cancer Cells Molecular Endocrinology (Baltimore, Md.). Jul, 2013 | Pubmed ID: 23660594 ALK Receptor Activation, Ligands and Therapeutic Targeting in Glioblastoma and in Other Cancers Frontiers in Oncology. 2012 | Pubmed ID: 23267434 Dietary Downregulation of Mutant P53 Levels Via Glucose Restriction: Mechanisms and Implications for Tumor Therapy Cell Cycle (Georgetown, Tex.). Dec, 2012 | Pubmed ID: 23151455 The Mitochondrial Citrate Transporter, CIC, is Essential for Mitochondrial Homeostasis Oncotarget. Oct, 2012 | Pubmed ID: 23100451 Pleiotrophin (PTN) Expression and Function and in the Mouse Mammary Gland and Mammary Epithelial Cells PloS One. 2012 | Pubmed ID: 23077670 Effects of the Antioxidant Drug Tempol on Renal Oxygenation in Mice with Reduced Renal Mass American Journal of Physiology. Renal Physiology. Jul, 2012 | Pubmed ID: 22492941 Role of the Nuclear Receptor Coactivator AIB1/SRC-3 in Angiogenesis and Wound Healing The American Journal of Pathology. Apr, 2012 | Pubmed ID: 22342158 P47(phox) is Required for Afferent Arteriolar Contractile Responses to Angiotensin II and Perfusion Pressure in Mice Hypertension. Feb, 2012 | Pubmed ID: 22184329 Impact of Fibroblast Growth Factor-binding Protein-1 Expression on Angiogenesis and Wound Healing The American Journal of Pathology. Nov, 2011 | Pubmed ID: 21945411 Superoxide Modulates Myogenic Contractions of Mouse Afferent Arterioles Hypertension. Oct, 2011 | Pubmed ID: 21859962 Tissue and Serum MicroRNAs in the Kras(G12D) Transgenic Animal Model and in Patients with Pancreatic Cancer PloS One. 2011 | Pubmed ID: 21738581 Proteomic Analysis of Pathways Involved in Estrogen-induced Growth and Apoptosis of Breast Cancer Cells PloS One. 2011 | Pubmed ID: 21738574 Role of the Nuclear Receptor Coactivator AIB1-Delta4 Splice Variant in the Control of Gene Transcription The Journal of Biological Chemistry. Jul, 2011 | Pubmed ID: 21636853 Hunting ALK to Feed Targeted Cancer Therapy Nature Medicine. Mar, 2011 | Pubmed ID: 21383740 Omics-based Molecular Target and Biomarker Identification Methods in Molecular Biology (Clifton, N.J.). 2011 | Pubmed ID: 21370102 A Distinct Role for Secreted Fibroblast Growth Factor-binding Proteins in Development Proceedings of the National Academy of Sciences of the United States of America. May, 2009 | Pubmed ID: 19433791 The Role and Regulation of the Nuclear Receptor Co-activator AIB1 in Breast Cancer Breast Cancer Research and Treatment. Jul, 2009 | Pubmed ID: 19418218 Tyrosine Phosphorylation of the Nuclear Receptor Coactivator AIB1/SRC-3 is Enhanced by Abl Kinase and is Required for Its Activity in Cancer Cells Molecular and Cellular Biology. Nov, 2008 | Pubmed ID: 18765637 Chronic Antidepressant Treatments Increase Basic Fibroblast Growth Factor and Fibroblast Growth Factor-binding Protein in Neurons Neuropharmacology. Dec, 2008 | Pubmed ID: 18682257 Effect of FGF-binding Protein 3 on Vascular Permeability The Journal of Biological Chemistry. Oct, 2008 | Pubmed ID: 18669637 The Nuclear Receptor Coactivator Amplified in Breast Cancer-1 is Required for Neu (ErbB2/HER2) Activation, Signaling, and Mammary Tumorigenesis in Mice Cancer Research. May, 2008 | Pubmed ID: 18483252 Epidermal Growth Factor Receptor Tyrosine Phosphorylation and Signaling Controlled by a Nuclear Receptor Coactivator, Amplified in Breast Cancer 1 Cancer Research. Aug, 2007 | Pubmed ID: 17671194 Effects on Neurite Outgrowth and Cell Survival of a Secreted Fibroblast Growth Factor Binding Protein Upregulated During Spinal Cord Injury American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Aug, 2007 | Pubmed ID: 17553847 Tumor Angiogenesis: Initiation and Targeting - Therapeutic Targeting of an FGF-binding Protein, an Angiogenic Switch Molecule, and Indicator of Early Stages of Gastrointestinal Adenocarcinomas - Cancer Research and Treatment : Official Journal of Korean Cancer Association. Dec, 2006 | Pubmed ID: 19771241 The Angiogenic Switch Molecule, Secreted FGF-binding Protein, an Indicator of Early Stages of Pancreatic and Colorectal Adenocarcinoma Seminars in Oncology. Dec, 2006 | Pubmed ID: 17178288 E6AP Mediates Regulated Proteasomal Degradation of the Nuclear Receptor Coactivator Amplified in Breast Cancer 1 in Immortalized Cells Cancer Research. Sep, 2006 | Pubmed ID: 16951183 Expression Analysis of MRNA in Formalin-fixed, Paraffin-embedded Archival Tissues by MRNA in Situ Hybridization Methods (San Diego, Calif.). Apr, 2006 | Pubmed ID: 16513366 Expression of a Fibroblast Growth Factor-binding Protein During the Development of Adenocarcinoma of the Pancreas and Colon Cancer Research. Jan, 2006 | Pubmed ID: 16424058 RNA Silencing in Vivo Reveals Role of P22phox in Rat Angiotensin Slow Pressor Response Hypertension. Feb, 2006 | Pubmed ID: 16391171 Role of Fibroblast Growth Factor-binding Protein in the Pathogenesis of HIV-associated Hemolytic Uremic Syndrome American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Jan, 2006 | Pubmed ID: 16352855 Identification of the Fibroblast Growth Factor (FGF)-interacting Domain in a Secreted FGF-binding Protein by Phage Display The Journal of Biological Chemistry. Jan, 2006 | Pubmed ID: 16257968 Vascular Leakage in Chick Embryos After Expression of a Secreted Binding Protein for Fibroblast Growth Factors Laboratory Investigation; a Journal of Technical Methods and Pathology. Jun, 2005 | Pubmed ID: 15806140 Heregulin-beta1 Regulates the Estrogen Receptor-alpha Gene Expression and Activity Via the ErbB2/PI 3-K/Akt Pathway Oncogene. Mar, 2005 | Pubmed ID: 15759010 The Nuclear Receptor Coactivator AIB1 Mediates Insulin-like Growth Factor I-induced Phenotypic Changes in Human Breast Cancer Cells Cancer Research. Nov, 2004 | Pubmed ID: 15548698 Differential Regulation of a Fibroblast Growth Factor-binding Protein During Skin Carcinogenesis and Wound Healing Neoplasia (New York, N.Y.). Sep-Oct, 2004 | Pubmed ID: 15548369 Overexpression of the Nuclear Receptor Coactivator AIB1 (SRC-3) During Progression of Pancreatic Adenocarcinoma Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Sep, 2004 | Pubmed ID: 15448000 Altered Rho GTPase Signaling Pathways in Breast Cancer Cells Breast Cancer Research and Treatment. Mar, 2004 | Pubmed ID: 14999153 Systemic Morphine Administration Suppresses Genes Involved in Antigen Presentation Molecular Pharmacology. Feb, 2004 | Pubmed ID: 14742686 Impact of the Nuclear Receptor Coactivator AIB1 Isoform AIB1-Delta3 on Estrogenic Ligands with Different Intrinsic Activity Oncogene. Jan, 2004 | Pubmed ID: 14691461 Up-regulation of Fibroblast Growth Factor-binding Protein, by Beta-catenin During Colon Carcinogenesis Cancer Research. Dec, 2003 | Pubmed ID: 14678957 Effect of Estradiol on Estrogen Receptor-alpha Gene Expression and Activity Can Be Modulated by the ErbB2/PI 3-K/Akt Pathway Oncogene. Sep, 2003 | Pubmed ID: 12970748 Heregulin-beta1 Regulates the Estrogen Receptor-alpha Gene Expression and Activity Via the ErbB2/PI 3-K/Akt Pathway Oncogene. Apr, 2003 | Pubmed ID: 12687010 Complex Regulation of the Fibroblast Growth Factor-binding Protein in MDA- MB-468 Breast Cancer Cells by CCAAT/enhancer-binding Protein Beta Cancer Research. Apr, 2003 | Pubmed ID: 12670924 Estradiol Rapidly Activates Akt Via the ErbB2 Signaling Pathway Molecular Endocrinology (Baltimore, Md.). May, 2003 | Pubmed ID: 12554767 A Role for TGF-beta in Estrogen and Retinoid Mediated Regulation of the Nuclear Receptor Coactivator AIB1 in MCF-7 Breast Cancer Cells Oncogene. Oct, 2002 | Pubmed ID: 12370804 Midkine Binds to Anaplastic Lymphoma Kinase (ALK) and Acts As a Growth Factor for Different Cell Types The Journal of Biological Chemistry. Sep, 2002 | Pubmed ID: 12122009 Anti-apoptotic Signaling of Pleiotrophin Through Its Receptor, Anaplastic Lymphoma Kinase The Journal of Biological Chemistry. Sep, 2002 | Pubmed ID: 12107166 Significance of the Expression of the Growth Factor Pleiotrophin in Pancreatic Cancer Patients Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Mar, 2002 | Pubmed ID: 11895915 Immunolocalization of an FGF-binding Protein Reveals a Widespread Expression Pattern During Different Stages of Mouse Embryo Development Histochemistry and Cell Biology. Jan, 2002 | Pubmed ID: 11819092 Pleiotrophin Signaling Through Anaplastic Lymphoma Kinase is Rate-limiting for Glioblastoma Growth The Journal of Biological Chemistry. Apr, 2002 | Pubmed ID: 11809760 Structure and Phylogenetic Analysis of an Endogenous Retrovirus Inserted into the Human Growth Factor Gene Pleiotrophin Journal of Virology. Jul, 1998 | Pubmed ID: 9621070 Human Trophoblast and Choriocarcinoma Expression of the Growth Factor Pleiotrophin Attributable to Germ-line Insertion of an Endogenous Retrovirus Proceedings of the National Academy of Sciences of the United States of America. Dec, 1996 | Pubmed ID: 8962128 Melanoma Angiogenesis and Metastasis Modulated by Ribozyme Targeting of the Secreted Growth Factor Pleiotrophin Proceedings of the National Academy of Sciences of the United States of America. Dec, 1996 | Pubmed ID: 8962127 Realtidsdetektering och fångst av invasiva cellsubpopulationer från samkulturer Ghada M. Sharif1, Leon Der2, Anna T. Riegel1, Makarand Paranjape2, Anton Wellstein1 1Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, 2Department of Physics, Georgetown University JoVE 63512 Ricerca sul cancro Övervakning Cancer Cell Invasion och T-Cell cytotoxicitet i 3D-kultur Yuan-Na Lin1, Apsra Nasir1, Sharon Camacho1, Deborah L. Berry1, Marcel O. Schmidt1, Gray W. Pearson1, Anna T. Riegel1, Anton Wellstein1 1Lombardi Comprehensive Cancer Center, Department of Oncology, Georgetown University JoVE 61392 Ricerca sul cancro Testa Vascular Invasive cancercellers förmåga i zebrafisk ( Eric B. Berens1, Ghada M. Sharif1, Anton Wellstein1, Eric Glasgow1 1Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University JoVE 55007 Ricerca sul cancro En Cancer Cell Spheroid analys för att bedöma invasion i en 3D-inställning Eric B. Berens1, Jon M. Holy2, Anna T. Riegel1, Anton Wellstein1 1Lombardi Comprehensive Cancer Center, Department of Oncology, Georgetown University, 2Department of Biomedical Sciences, University of Minnesota Medicina
Realtidsdetektering och fångst av invasiva cellsubpopulationer från samkulturer Ghada M. Sharif1, Leon Der2, Anna T. Riegel1, Makarand Paranjape2, Anton Wellstein1 1Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, 2Department of Physics, Georgetown University JoVE 63512 Ricerca sul cancro
Övervakning Cancer Cell Invasion och T-Cell cytotoxicitet i 3D-kultur Yuan-Na Lin1, Apsra Nasir1, Sharon Camacho1, Deborah L. Berry1, Marcel O. Schmidt1, Gray W. Pearson1, Anna T. Riegel1, Anton Wellstein1 1Lombardi Comprehensive Cancer Center, Department of Oncology, Georgetown University JoVE 61392 Ricerca sul cancro
Testa Vascular Invasive cancercellers förmåga i zebrafisk ( Eric B. Berens1, Ghada M. Sharif1, Anton Wellstein1, Eric Glasgow1 1Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University JoVE 55007 Ricerca sul cancro
En Cancer Cell Spheroid analys för att bedöma invasion i en 3D-inställning Eric B. Berens1, Jon M. Holy2, Anna T. Riegel1, Anton Wellstein1 1Lombardi Comprehensive Cancer Center, Department of Oncology, Georgetown University, 2Department of Biomedical Sciences, University of Minnesota Medicina