Beat Lutz Institute of Physiological Chemistry University Medical Center of the Johannes Gutenberg University Mainz Biography Publications Institution JoVE Articles Beat Lutz has not added a biography. If you are Beat Lutz and would like to personalize this page please email our Author Liaison for assistance. Publications Cell Type-specific Genetic Reconstitution of CB1 Receptor Subsets to Assess Their Role in Exploratory Behaviour, Sociability, and Memory The European Journal of Neuroscience. Feb, 2022 | Pubmed ID: 33253450 Association of Innate and Acquired Aerobic Capacity With Resilience in Healthy Adults: Protocol for a Randomized Controlled Trial of an 8-Week Web-Based Physical Exercise Intervention JMIR Research Protocols. Nov, 2021 | Pubmed ID: 34847062 Subsynaptic Distribution, Lipid Raft Targeting and G Protein-Dependent Signalling of the Type 1 Cannabinoid Receptor in Synaptosomes from the Mouse Hippocampus and Frontal Cortex Molecules (Basel, Switzerland). Nov, 2021 | Pubmed ID: 34833992 Stress-Related Dysfunction of Adult Hippocampal Neurogenesis-An Attempt for Understanding Resilience? International Journal of Molecular Sciences. Jul, 2021 | Pubmed ID: 34298958 Cannabis Use and Car Crashes: A Review Frontiers in Psychiatry. 2021 | Pubmed ID: 34122176 Transcriptional Signatures in Prefrontal Cortex Confer Vulnerability Versus Resilience to Food and Cocaine Addiction-like Behavior Scientific Reports. 04, 2021 | Pubmed ID: 33907201 Chronic Social Stress Lessens the Metabolic Effects Induced by a High-fat Diet The Journal of Endocrinology. 04, 2021 | Pubmed ID: 33608492 Exercise-induced Euphoria and Anxiolysis Do Not Depend on Endogenous Opioids in Humans Psychoneuroendocrinology. 04, 2021 | Pubmed ID: 33582575 Cannabinoid CB1 Receptor in Dorsal Telencephalic Glutamatergic Neurons Drives Overconsumption of Palatable Food and Obesity Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 04, 2021 | Pubmed ID: 33558679 The Endocannabinoid 2-arachidonoylglycerol Inhibits Endothelial Function and Repair International Journal of Cardiology. 01, 2021 | Pubmed ID: 32810540 Quantification of the Cannabinoid Type 1 Receptor Availability in the Mouse Brain Frontiers in Neuroanatomy. 2020 | Pubmed ID: 33328905 Differential Glutamatergic and GABAergic Contributions to the Tetrad Effects of Δ-tetrahydrocannabinol Revealed by Cell-type-specific Reconstitution of the CB1 Receptor Neuropharmacology. 11, 2020 | Pubmed ID: 32860777 A Specific Prelimbic-nucleus Accumbens Pathway Controls Resilience Versus Vulnerability to Food Addiction Nature Communications. 02, 2020 | Pubmed ID: 32034128 Long-term Hippocampal Interneuronopathy Drives Sex-dimorphic Spatial Memory Impairment Induced by Prenatal THC Exposure Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 04, 2020 | Pubmed ID: 31982904 Cell Type Specific Impact of Cannabinoid Receptor Signaling in Somatosensory Barrel Map Formation in Mice The Journal of Comparative Neurology. 01, 2020 | Pubmed ID: 31226222 Endocannabinoid 2-arachidonoylglycerol is Elevated in the Coronary Circulation During Acute Coronary Syndrome PloS One. 2019 | Pubmed ID: 31887202 Adipocyte Cannabinoid CB1 Receptor Deficiency Alleviates High Fat Diet-induced Memory Deficit, Depressive-like Behavior, Neuroinflammation and Impairment in Adult Neurogenesis Psychoneuroendocrinology. 12, 2019 | Pubmed ID: 31491589 Broad Lipidomic and Transcriptional Changes of Prophylactic PEA Administration in Adult Mice Frontiers in Neuroscience. 2019 | Pubmed ID: 31244590 Gadd45α Modulates Aversive Learning Through Post-transcriptional Regulation of Memory-related MRNAs EMBO Reports. 06, 2019 | Pubmed ID: 30948457 Multiple Endocannabinoid-mediated Mechanisms in the Regulation of Energy Homeostasis in Brain and Peripheral Tissues Cellular and Molecular Life Sciences : CMLS. Apr, 2019 | Pubmed ID: 30599065 Impaired Anandamide/palmitoylethanolamide Signaling in Hippocampal Glutamatergic Neurons Alters Synaptic Plasticity, Learning, and Emotional Responses Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 07, 2019 | Pubmed ID: 30532004 Publisher Correction: Maladaptive Cortical Hyperactivity Upon Recovery from Experimental Autoimmune Encephalomyelitis Nature Neuroscience. Jan, 2019 | Pubmed ID: 30405214 Prophylactic Palmitoylethanolamide Prolongs Survival and Decreases Detrimental Inflammation in Aged Mice With Bacterial Meningitis Frontiers in Immunology. 2018 | Pubmed ID: 30505308 Neural Stem Cell Lineage-specific Cannabinoid Type-1 Receptor Regulates Neurogenesis and Plasticity in the Adult Mouse Hippocampus Cerebral Cortex (New York, N.Y. : 1991). 12, 2018 | Pubmed ID: 30307491 Maladaptive Cortical Hyperactivity Upon Recovery from Experimental Autoimmune Encephalomyelitis Nature Neuroscience. 10, 2018 | Pubmed ID: 30258239 Elevated Levels of 2-arachidonoylglycerol Promote Atherogenesis in ApoE-/- Mice PloS One. 2018 | Pubmed ID: 29813086 Localization of the Cannabinoid Type-1 Receptor in Subcellular Astrocyte Compartments of Mutant Mouse Hippocampus Glia. 07, 2018 | Pubmed ID: 29480581 Age-related Regulation of Bone Formation by the Sympathetic Cannabinoid CB1 Receptor Bone. 03, 2018 | Pubmed ID: 29274505 Pharmacokinetics of the Cannabinoid Receptor Ligand [ F]MK-9470 in the Rat Brain - Evaluation of Models Using MicroPET Medical Physics. Feb, 2018 | Pubmed ID: 29244904 Discovery and Characterization of Two Novel CB1 Receptor Splice Variants with Modified N-termini in Mouse Journal of Neurochemistry. 08, 2017 | Pubmed ID: 28608535 Chemical Probes to Potently and Selectively Inhibit Endocannabinoid Cellular Reuptake Proceedings of the National Academy of Sciences of the United States of America. 06, 2017 | Pubmed ID: 28584105 Abstracts of the 52nd Workshop for Pediatric Research : Frankfurt, Germany. 27-28 October 2016 Molecular and Cellular Pediatrics. May, 2017 | Pubmed ID: 28516419 Addressing Sufficiency of the CB1 Receptor for Endocannabinoid-mediated Functions Through Conditional Genetic Rescue in Forebrain GABAergic Neurons Brain Structure & Function. Nov, 2017 | Pubmed ID: 28393261 Singular Location and Signaling Profile of Adenosine A2A-Cannabinoid CB1 Receptor Heteromers in the Dorsal Striatum Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. Feb, 2017 | Pubmed ID: 28102227 Targeting Brain and Peripheral Plasticity of the Lipidome in Acute Kainic Acid-induced Epileptic Seizures in Mice Via Quantitative Mass Spectrometry Biochimica Et Biophysica Acta. Molecular and Cell Biology of Lipids. Feb, 2017 | Pubmed ID: 27871881 Anatomical Characterization of the Cannabinoid CB Receptor in Cell-type-specific Mutant Mouse Rescue Models The Journal of Comparative Neurology. 02, 2017 | Pubmed ID: 27339436 Adverse Social Experiences in Adolescent Rats Result in Enduring Effects on Social Competence, Pain Sensitivity and Endocannabinoid Signaling Frontiers in Behavioral Neuroscience. 2016 | Pubmed ID: 27812328 Restricted Vs. Unrestricted Wheel Running in Mice: Effects on Brain, Behavior and Endocannabinoids Hormones and Behavior. 11, 2016 | Pubmed ID: 27664019 Cell Type-Specific Tandem Affinity Purification of the Mouse Hippocampal CB1 Receptor-Associated Proteome Journal of Proteome Research. 10, 2016 | Pubmed ID: 27596989 Peripheral and Central CB1 Cannabinoid Receptors Control Stress-induced Impairment of Memory Consolidation Proceedings of the National Academy of Sciences of the United States of America. 08, 2016 | Pubmed ID: 27528659 Extraction and Simultaneous Quantification of Endocannabinoids and Endocannabinoid-Like Lipids in Biological Tissues Methods in Molecular Biology (Clifton, N.J.). 2016 | Pubmed ID: 27245887 Lack of Hippocampal CB1 Receptor Desensitization by Δ(9)-tetrahydrocannabinol in Aged Mice and by Low Doses of JZL 184 Naunyn-Schmiedeberg's Archives of Pharmacology. Jun, 2016 | Pubmed ID: 26984820 Anxiety, Stress, and Fear Response in Mice With Reduced Endocannabinoid Levels Biological Psychiatry. 05, 2016 | Pubmed ID: 25981172 Evaluation of MRI and Cannabinoid Type 1 Receptor PET Templates Constructed Using DARTEL for Spatial Normalization of Rat Brains Medical Physics. Dec, 2015 | Pubmed ID: 26632044 The Cannabinoid Receptor CB1 Interacts with the WAVE1 Complex and Plays a Role in Actin Dynamics and Structural Plasticity in Neurons PLoS Biology. Oct, 2015 | Pubmed ID: 26496209 Enhanced Functional Activity of the Cannabinoid Type-1 Receptor Mediates Adolescent Behavior The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2015 | Pubmed ID: 26468198 Prenatal Exposure to Cannabinoids Evokes Long-lasting Functional Alterations by Targeting CB1 Receptors on Developing Cortical Neurons Proceedings of the National Academy of Sciences of the United States of America. Nov, 2015 | Pubmed ID: 26460022 A Runner's High Depends on Cannabinoid Receptors in Mice Proceedings of the National Academy of Sciences of the United States of America. Oct, 2015 | Pubmed ID: 26438875 Cannabinoid Type-1 Receptor Signaling in Central Serotonergic Neurons Regulates Anxiety-like Behavior and Sociability Frontiers in Behavioral Neuroscience. 2015 | Pubmed ID: 26388750 Age-related Changes in the Endocannabinoid System in the Mouse Hippocampus Mechanisms of Ageing and Development. Sep, 2015 | Pubmed ID: 26278494 Impaired Border Zone Formation and Adverse Remodeling After Reperfused Myocardial Infarction in Cannabinoid CB2 Receptor Deficient Mice Life Sciences. Oct, 2015 | Pubmed ID: 25447445 Oligodendrocyte Precursor Cells Modulate the Neuronal Network by Activity-dependent Ectodomain Cleavage of Glial NG2 PLoS Biology. Nov, 2014 | Pubmed ID: 25387269 A Restricted Population of CB1 Cannabinoid Receptors with Neuroprotective Activity Proceedings of the National Academy of Sciences of the United States of America. Jun, 2014 | Pubmed ID: 24843137 Endocannabinoid Anandamide Mediates Hypoxic Pulmonary Vasoconstriction Proceedings of the National Academy of Sciences of the United States of America. Nov, 2013 | Pubmed ID: 24167249 Cannabinoid CB1 Receptor in Dorsal Telencephalic Glutamatergic Neurons: Distinctive Sufficiency for Hippocampus-dependent and Amygdala-dependent Synaptic and Behavioral Functions The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2013 | Pubmed ID: 23785142 Neuron-type Specific Cannabinoid-mediated G Protein Signalling in Mouse Hippocampus Journal of Neurochemistry. Mar, 2013 | Pubmed ID: 23289830 Identification and Quantification of a New Family of Peptide Endocannabinoids (Pepcans) Showing Negative Allosteric Modulation at CB1 Receptors The Journal of Biological Chemistry. Oct, 2012 | Pubmed ID: 22952224 A Polymorphism in the Gene of the Endocannabinoid-degrading Enzyme FAAH (FAAH C385A) is Associated with Emotional-motivational Reactivity Psychopharmacology. Dec, 2012 | Pubmed ID: 22776995 Circuit Specific Functions of Cannabinoid CB1 Receptor in the Balance of Investigatory Drive and Exploration PloS One. 2011 | Pubmed ID: 22069458 Ablation of CBP in Forebrain Principal Neurons Causes Modest Memory and Transcriptional Defects and a Dramatic Reduction of Histone Acetylation but Does Not Affect Cell Viability The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2011 | Pubmed ID: 21289174 Alterations in the Hippocampal Endocannabinoid System in Diet-induced Obese Mice The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2010 | Pubmed ID: 20445053 Lipidomikk og transskriftomikk ved nevrologiske sykdommer Julia M. Post1, Raissa Lerner1, Claudia Schwitter1, Beat Lutz1, Ermelinda Lomazzo1, Laura Bindila1 1Institute of Physiological Chemistry, University Medical Center of the Johannes Gutenberg University Mainz JoVE 59423 Neuroscienze
Lipidomikk og transskriftomikk ved nevrologiske sykdommer Julia M. Post1, Raissa Lerner1, Claudia Schwitter1, Beat Lutz1, Ermelinda Lomazzo1, Laura Bindila1 1Institute of Physiological Chemistry, University Medical Center of the Johannes Gutenberg University Mainz JoVE 59423 Neuroscienze