Bernd Schmeck Institute for Lung Research, Universities of Giessen and Marburg Lung Center Philipps-University Marburg Biography Publications Institution JoVE Articles Bernd Schmeck has not added a biography. If you are Bernd Schmeck and would like to personalize this page please email our Author Liaison for assistance. Publications An Interactive Macrophage Signal Transduction Map Facilitates Comparative Analyses of High-Throughput Data Journal of Immunology (Baltimore, Md. : 1950). Jan, 2017 | Pubmed ID: 28137890 Current Concepts in Chronic Inflammatory Diseases: Interactions Between Microbes, Cellular Metabolism, and Inflammation The Journal of Allergy and Clinical Immunology. Jul, 2016 | Pubmed ID: 27373325 Genome-wide Chromatin Profiling of Legionella Pneumophila-Infected Human Macrophages Reveals Activation of the Probacterial Host Factor TNFAIP2 The Journal of Infectious Diseases. Aug, 2016 | Pubmed ID: 27130431 Legionella Pneumophila-Derived Outer Membrane Vesicles Promote Bacterial Replication in Macrophages PLoS Pathogens. Apr, 2016 | Pubmed ID: 27105429 MicroRNAs Constitute a Negative Feedback Loop in Streptococcus Pneumoniae-Induced Macrophage Activation The Journal of Infectious Diseases. Jul, 2016 | Pubmed ID: 26984146 Annexin A1 Sustains Tumor Metabolism and Cellular Proliferation Upon Stable Loss of HIF1A Oncotarget. Feb, 2016 | Pubmed ID: 26760764 Third-Kind Encounters in Biomedicine: Immunology Meets Mathematics and Informatics to Become Quantitative and Predictive Methods in Molecular Biology (Clifton, N.J.). 2016 | Pubmed ID: 26677184 Systems Medicine for Lung Diseases: Phenotypes and Precision Medicine in Cancer, Infection, and Allergy Methods in Molecular Biology (Clifton, N.J.). 2016 | Pubmed ID: 26677183 Training in Systems Approaches for the Next Generation of Life Scientists and Medical Doctors Methods in Molecular Biology (Clifton, N.J.). 2016 | Pubmed ID: 26677180 Therapy with Plasma Purified Alpha1-antitrypsin (Prolastin®) Induces Time-dependent Changes in Plasma Levels of MMP-9 and MPO PloS One. 2015 | Pubmed ID: 25635861 Impaired TLR4 and HIF Expression in Cystic Fibrosis Bronchial Epithelial Cells Downregulates Hemeoxygenase-1 and Alters Iron Homeostasis in Vitro American Journal of Physiology. Lung Cellular and Molecular Physiology. Nov, 2014 | Pubmed ID: 25239913 Malignancy Associated MicroRNA Expression Changes in Canine Mammary Cancer of Different Malignancies ISRN Veterinary Science. 2014 | Pubmed ID: 25002976 Benefits of Whole Body Vibration Training in Patients Hospitalised for COPD Exacerbations - a Randomized Clinical Trial BMC Pulmonary Medicine. Apr, 2014 | Pubmed ID: 24725369 MicroRNAs in the Lung Advances in Experimental Medicine and Biology. 2013 | Pubmed ID: 23377971 Asthma Phenotyping, Therapy, and Prevention: What Can We Learn from Systems Biology? Pediatric Research. Apr, 2013 | Pubmed ID: 23314293 TLR9- and Src-dependent Expression of Krueppel-like Factor 4 Controls Interleukin-10 Expression in Pneumonia The European Respiratory Journal. Feb, 2013 | Pubmed ID: 22653776 Systems Biology and Bioinformatics in Aging Research: a Workshop Report Rejuvenation Research. Dec, 2012 | Pubmed ID: 22950424 Rac1 Regulates the NLRP3 Inflammasome Which Mediates IL-1beta Production in Chlamydophila Pneumoniae Infected Human Mononuclear Cells PloS One. 2012 | Pubmed ID: 22276187 Simvastatin Attenuates Ventilator-induced Lung Injury in Mice Critical Care (London, England). 2010 | Pubmed ID: 20673352 Legionella Pneumophila Induces Human Beta Defensin-3 in Pulmonary Cells Respiratory Research. Jul, 2010 | Pubmed ID: 20615218 TLR2- and Nucleotide-binding Oligomerization Domain 2-dependent Krüppel-like Factor 2 Expression Downregulates NF-kappa B-related Gene Expression Journal of Immunology (Baltimore, Md. : 1950). Jul, 2010 | Pubmed ID: 20525885 Listeria Monocytogenes-infected Human Peripheral Blood Mononuclear Cells Produce IL-1beta, Depending on Listeriolysin O and NLRP3 Journal of Immunology (Baltimore, Md. : 1950). Jan, 2010 | Pubmed ID: 20008285 Statins Control Oxidized LDL-mediated Histone Modifications and Gene Expression in Cultured Human Endothelial Cells Arteriosclerosis, Thrombosis, and Vascular Biology. Mar, 2009 | Pubmed ID: 19122173 Phosphodiesterase 2 Inhibition Diminished Acute Lung Injury in Murine Pneumococcal Pneumonia Critical Care Medicine. Feb, 2009 | Pubmed ID: 19114892 Systemic Use of the Endolysin Cpl-1 Rescues Mice with Fatal Pneumococcal Pneumonia Critical Care Medicine. Feb, 2009 | Pubmed ID: 19114881 Beta-PIX and Rac1 GTPase Mediate Trafficking and Negative Regulation of NOD2 Journal of Immunology (Baltimore, Md. : 1950). Aug, 2008 | Pubmed ID: 18684957 Histone Acetylation and Flagellin Are Essential for Legionella Pneumophila-induced Cytokine Expression Journal of Immunology (Baltimore, Md. : 1950). Jul, 2008 | Pubmed ID: 18606645 NAIP and Ipaf Control Legionella Pneumophila Replication in Human Cells Journal of Immunology (Baltimore, Md. : 1950). May, 2008 | Pubmed ID: 18453601 Rho-kinase and Contractile Apparatus Proteins in Murine Airway Hyperresponsiveness Experimental and Toxicologic Pathology : Official Journal of the Gesellschaft Fur Toxikologische Pathologie. Jun, 2008 | Pubmed ID: 18434112 Simvastatin Reduces Chlamydophila Pneumoniae-mediated Histone Modifications and Gene Expression in Cultured Human Endothelial Cells Circulation Research. Apr, 2008 | Pubmed ID: 18309103 Proteomic Characterization of the Whole Secretome of Legionella Pneumophila and Functional Analysis of Outer Membrane Vesicles Infection and Immunity. May, 2008 | Pubmed ID: 18250176 Cell-specific Interleukin-15 and Interleukin-15 Receptor Subunit Expression and Regulation in Pneumococcal Pneumonia--comparison to Chlamydial Lung Infection Cytokine. May, 2007 | Pubmed ID: 17611121 Role of Platelet-activating Factor in Pneumolysin-induced Acute Lung Injury Critical Care Medicine. Jul, 2007 | Pubmed ID: 17522574 The UspA1 Protein of Moraxella Catarrhalis Induces CEACAM-1-dependent Apoptosis in Alveolar Epithelial Cells The Journal of Infectious Diseases. Jun, 2007 | Pubmed ID: 17471435 Adrenomedullin Reduces Vascular Hyperpermeability and Improves Survival in Rat Septic Shock Intensive Care Medicine. Apr, 2007 | Pubmed ID: 17318497 Comparative Transcriptional Profiling of the Lung Reveals Shared and Distinct Features of Streptococcus Pneumoniae and Influenza A Virus Infection Immunology. Mar, 2007 | Pubmed ID: 17163962 IFNbeta Induction by Influenza A Virus is Mediated by RIG-I Which is Regulated by the Viral NS1 Protein Cellular Microbiology. Apr, 2007 | Pubmed ID: 17140406 Legionella Pneumophila-induced PKCalpha-, MAPK-, and NF-kappaB-dependent COX-2 Expression in Human Lung Epithelium American Journal of Physiology. Lung Cellular and Molecular Physiology. Jan, 2007 | Pubmed ID: 17012371 Legionella Pneumophila Induces IFNbeta in Lung Epithelial Cells Via IPS-1 and IRF3, Which Also Control Bacterial Replication The Journal of Biological Chemistry. Nov, 2006 | Pubmed ID: 16984921 Listeria Monocytogenes Induced Rac1-dependent Signal Transduction in Endothelial Cells Biochemical Pharmacology. Nov, 2006 | Pubmed ID: 16884694 Streptococcus Pneumoniae Induced C-Jun-N-terminal Kinase- and AP-1 -dependent IL-8 Release by Lung Epithelial BEAS-2B Cells Respiratory Research. Jul, 2006 | Pubmed ID: 16834785 Lung Epithelium As a Sentinel and Effector System in Pneumonia--molecular Mechanisms of Pathogen Recognition and Signal Transduction Respiratory Research. Jul, 2006 | Pubmed ID: 16827942 Role of Pneumolysin for the Development of Acute Lung Injury in Pneumococcal Pneumonia Critical Care Medicine. Jul, 2006 | Pubmed ID: 16715037 Perturbation of Endothelial Junction Proteins by Staphylococcus Aureus Alpha-toxin: Inhibition of Endothelial Gap Formation by Adrenomedullin Histochemistry and Cell Biology. Sep, 2006 | Pubmed ID: 16596365 Streptococcus Pneumoniae Induced P38 MAPK- and NF-kappaB-dependent COX-2 Expression in Human Lung Epithelium American Journal of Physiology. Lung Cellular and Molecular Physiology. Jun, 2006 | Pubmed ID: 16414978 Moraxella Catarrhalis Induces Inflammatory Response of Bronchial Epithelial Cells Via MAPK and NF-kappaB Activation and Histone Deacetylase Activity Reduction American Journal of Physiology. Lung Cellular and Molecular Physiology. May, 2006 | Pubmed ID: 16399788 Listeria Monocytogenes Activated P38 MAPK and Induced IL-8 Secretion in a Nucleotide-binding Oligomerization Domain 1-dependent Manner in Endothelial Cells Journal of Immunology (Baltimore, Md. : 1950). Jan, 2006 | Pubmed ID: 16365441 Mechanisms of Chlamydophila Pneumoniae-mediated GM-CSF Release in Human Bronchial Epithelial Cells American Journal of Respiratory Cell and Molecular Biology. Mar, 2006 | Pubmed ID: 16340003 Pneumococci Induced TLR- and Rac1-dependent NF-kappaB-recruitment to the IL-8 Promoter in Lung Epithelial Cells American Journal of Physiology. Lung Cellular and Molecular Physiology. Apr, 2006 | Pubmed ID: 16299055 Adhesion of Moraxella Catarrhalis to Human Bronchial Epithelium Characterized by a Novel Fluorescence-based Assay Medical Microbiology and Immunology. Jun, 2006 | Pubmed ID: 16059698 Adrenomedullin Treatment Abolishes Ileal Mucosal Hypoperfusion Induced by Staphylococcus Aureus Alpha-toxin--an Intravital Microscopic Study on an Isolated Rat Ileum Critical Care Medicine. Dec, 2005 | Pubmed ID: 16352964 Intracellular Bacteria Differentially Regulated Endothelial Cytokine Release by MAPK-dependent Histone Modification Journal of Immunology (Baltimore, Md. : 1950). Sep, 2005 | Pubmed ID: 16116170 Streptococcus Pneumoniae R6x Induced P38 MAPK and JNK-mediated Caspase-dependent Apoptosis in Human Endothelial Cells Thrombosis and Haemostasis. Aug, 2005 | Pubmed ID: 16113818 Adrenomedullin Reduces Staphylococcus Aureus Alpha-toxin-induced Rat Ileum Microcirculatory Damage Critical Care Medicine. Apr, 2005 | Pubmed ID: 15818111 Nod1-mediated Endothelial Cell Activation by Chlamydophila Pneumoniae Circulation Research. Feb, 2005 | Pubmed ID: 15653568 Neuronal Plasticity in Persistent Perennial Allergic Rhinitis Journal of Occupational and Environmental Medicine. Jan, 2005 | Pubmed ID: 15643155 Streptococcus Pneumoniae-induced P38 MAPK-dependent Phosphorylation of RelA at the Interleukin-8 Promotor The Journal of Biological Chemistry. Dec, 2004 | Pubmed ID: 15485852 Porphyromonas Gingivalis Strain-dependent Activation of Human Endothelial Cells Infection and Immunity. Oct, 2004 | Pubmed ID: 15385493 Streptococcus Pneumoniae-induced Caspase 6-dependent Apoptosis in Lung Epithelium Infection and Immunity. Sep, 2004 | Pubmed ID: 15321985 Nucleotide-binding Oligomerization Domain Proteins Are Innate Immune Receptors for Internalized Streptococcus Pneumoniae The Journal of Biological Chemistry. Aug, 2004 | Pubmed ID: 15215247 Rho Protein Inhibition Blocks Cyclooxygenase-2 Expression by Proinflammatory Mediators in Endothelial Cells Inflammation. Apr, 2003 | Pubmed ID: 12797548 Adrenomedullin Reduces Endothelial Hyperpermeability Circulation Research. Oct, 2002 | Pubmed ID: 12364390 Rho Protein Inactivation Induced Apoptosis of Cultured Human Endothelial Cells American Journal of Physiology. Lung Cellular and Molecular Physiology. Oct, 2002 | Pubmed ID: 12225960 Reduction of Tumor Necrosis Factor-alpha (TNF-alpha) Related Nuclear Factor-kappaB (NF-kappaB) Translocation but Not Inhibitor Kappa-B (Ikappa-B)-degradation by Rho Protein Inhibition in Human Endothelial Cells Biochemical Pharmacology. Sep, 2002 | Pubmed ID: 12213594 लीजोनेला pneumophila बाहरी झिल्ली Vesicles: अलगाव और मैक्रोफेज पर उनके समर्थक भड़काऊ संभावित का विश्लेषण Anna Lena Jung1, Kerstin Hoffmann1, Christina E. Herkt1, Christine Schulz1, Wilhelm Bertrams1, Bernd Schmeck1,2,3 1Institute for Lung Research, Universities of Giessen and Marburg Lung Center, Philipps-University Marburg, 2German Center for Lung Research, 3Department of Medicine, Pulmonary and Critical Care Medicine, University Medical Center Giessen and Marburg JoVE 55146 Immunologia e infezioni
लीजोनेला pneumophila बाहरी झिल्ली Vesicles: अलगाव और मैक्रोफेज पर उनके समर्थक भड़काऊ संभावित का विश्लेषण Anna Lena Jung1, Kerstin Hoffmann1, Christina E. Herkt1, Christine Schulz1, Wilhelm Bertrams1, Bernd Schmeck1,2,3 1Institute for Lung Research, Universities of Giessen and Marburg Lung Center, Philipps-University Marburg, 2German Center for Lung Research, 3Department of Medicine, Pulmonary and Critical Care Medicine, University Medical Center Giessen and Marburg JoVE 55146 Immunologia e infezioni