Christopher C.W. Hughes Department of Molecular Biology and Biochemistry University of California, Irvine (UCI) Biography Publications Institution JoVE Articles Christopher C.W. Hughes has not added a biography. If you are Christopher C.W. Hughes and would like to personalize this page please email our Author Liaison for assistance. Publications A Role for Partial Endothelial-mesenchymal Transitions in Angiogenesis? Arteriosclerosis, Thrombosis, and Vascular Biology. Feb, 2015 | Pubmed ID: 25425619 A Three-dimensional in Vitro Model of Tumor Cell Intravasation Integrative Biology : Quantitative Biosciences from Nano to Macro. Jun, 2014 | Pubmed ID: 24763498 Interferon-induced Transmembrane Protein 1 Regulates Endothelial Lumen Formation During Angiogenesis Arteriosclerosis, Thrombosis, and Vascular Biology. May, 2014 | Pubmed ID: 24603679 Implanted Cell-dense Prevascularized Tissues Develop Functional Vasculature That Supports Reoxygenation After Thrombosis Tissue Engineering. Part A. Sep, 2014 | Pubmed ID: 24593148 Angiogenic Sprouting is Regulated by Endothelial Cell Expression of Slug Journal of Cell Science. May, 2014 | Pubmed ID: 24554431 A Microfluidic Platform for Generating Large-scale Nearly Identical Human Microphysiological Vascularized Tissue Arrays Lab on a Chip. Aug, 2013 | Pubmed ID: 23723013 In Vitro Perfused Human Capillary Networks Tissue Engineering. Part C, Methods. Sep, 2013 | Pubmed ID: 23320912 Analysis of Stromal Cell Secretomes Reveals a Critical Role for Stromal Cell-derived Hepatocyte Growth Factor and Fibronectin in Angiogenesis Arteriosclerosis, Thrombosis, and Vascular Biology. Mar, 2013 | Pubmed ID: 23288153 Full Range Physiological Mass Transport Control in 3D Tissue Cultures Lab on a Chip. Jan, 2013 | Pubmed ID: 23090158 Macrophages and Angiogenesis: a Role for Wnt Signaling Vascular Cell. 2012 | Pubmed ID: 22938389 BMP9 Induces EphrinB2 Expression in Endothelial Cells Through an Alk1-BMPRII/ActRII-ID1/ID3-dependent Pathway: Implications for Hereditary Hemorrhagic Telangiectasia Type II Angiogenesis. Sep, 2012 | Pubmed ID: 22622516 Longitudinal in Vivo Imaging to Assess Blood Flow and Oxygenation in Implantable Engineered Tissues Tissue Engineering. Part C, Methods. Sep, 2012 | Pubmed ID: 22435776 Mouse and Human Strategies Identify PTPN14 As a Modifier of Angiogenesis and Hereditary Haemorrhagic Telangiectasia Nature Communications. 2012 | Pubmed ID: 22233626 The Requirement for Fibroblasts in Angiogenesis: Fibroblast-derived Matrix Proteins Are Essential for Endothelial Cell Lumen Formation Molecular Biology of the Cell. Oct, 2011 | Pubmed ID: 21865599 Estradiol Stimulates Capillary Formation by Human Endothelial Progenitor Cells: Role of Estrogen Receptor-{alpha}/{beta}, Heme Oxygenase 1, and Tyrosine Kinase Hypertension. Sep, 2010 | Pubmed ID: 20644008 Rapid Anastomosis of Endothelial Progenitor Cell-derived Vessels with Host Vasculature is Promoted by a High Density of Cotransplanted Fibroblasts Tissue Engineering. Part A. Feb, 2010 | Pubmed ID: 19737050 Integration of the Beta-catenin-dependent Wnt Pathway with Integrin Signaling Through the Adaptor Molecule Grb2 PloS One. 2009 | Pubmed ID: 19924227 TNF Induction of Jagged-1 in Endothelial Cells is NFkappaB-dependent Gene. Apr, 2009 | Pubmed ID: 19393188 Prevascularization of a Fibrin-based Tissue Construct Accelerates the Formation of Functional Anastomosis with Host Vasculature Tissue Engineering. Part A. Jun, 2009 | Pubmed ID: 18976155 The Anti-cancer Drug Lenalidomide Inhibits Angiogenesis and Metastasis Via Multiple Inhibitory Effects on Endothelial Cell Function in Normoxic and Hypoxic Conditions Microvascular Research. Mar, 2009 | Pubmed ID: 18805433 An Optimized Three-dimensional in Vitro Model for the Analysis of Angiogenesis Methods in Enzymology. 2008 | Pubmed ID: 18772011 Endothelial-stromal Interactions in Angiogenesis Current Opinion in Hematology. May, 2008 | Pubmed ID: 18391786 Crosstalk Between Vascular Endothelial Growth Factor, Notch, and Transforming Growth Factor-beta in Vascular Morphogenesis Circulation Research. Mar, 2008 | Pubmed ID: 18369162 TNF Primes Endothelial Cells for Angiogenic Sprouting by Inducing a Tip Cell Phenotype Blood. May, 2008 | Pubmed ID: 18337563 The Effect of Matrix Density on the Regulation of 3-D Capillary Morphogenesis Biophysical Journal. Mar, 2008 | Pubmed ID: 17993494 Wnt Signaling Induces Matrix Metalloproteinase Expression and Regulates T Cell Transmigration Immunity. Feb, 2007 | Pubmed ID: 17306568 Mesenchymal Stem Cells Enhance Angiogenesis in Mechanically Viable Prevascularized Tissues Via Early Matrix Metalloproteinase Upregulation Tissue Engineering. Oct, 2006 | Pubmed ID: 17518656 HESR1/CHF2 Suppresses VEGFR2 Transcription Independent of Binding to E-boxes Biochemical and Biophysical Research Communications. Aug, 2006 | Pubmed ID: 16782059 Immunomodulatory Drugs (IMiDs) Increase the Production of IL-2 from Stimulated T Cells by Increasing PKC-theta Activation and Enhancing the DNA-binding Activity of AP-1 but Not NF-kappaB, OCT-1, or NF-AT Journal of Interferon & Cytokine Research : the Official Journal of the International Society for Interferon and Cytokine Research. Oct, 2005 | Pubmed ID: 16241859 Endothelial Cell Co-stimulation Through OX40 Augments and Prolongs T Cell Cytokine Synthesis by Stabilization of Cytokine MRNA International Immunology. Jun, 2005 | Pubmed ID: 15908450 Cell-autonomous Notch Signaling Regulates Endothelial Cell Branching and Proliferation During Vascular Tubulogenesis FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jun, 2005 | Pubmed ID: 15774577 Diffusion Limits of an in Vitro Thick Prevascularized Tissue Tissue Engineering. Jan-Feb, 2005 | Pubmed ID: 15738680 Of Mice and Not Men: Differences Between Mouse and Human Immunology Journal of Immunology (Baltimore, Md. : 1950). Mar, 2004 | Pubmed ID: 14978070 VEGF(121) and VEGF(165) Regulate Blood Vessel Diameter Through Vascular Endothelial Growth Factor Receptor 2 in an in Vitro Angiogenesis Model Laboratory Investigation; a Journal of Technical Methods and Pathology. Dec, 2003 | Pubmed ID: 14691306 Angiogenic Sprouting and Capillary Lumen Formation Modeled by Human Umbilical Vein Endothelial Cells (HUVEC) in Fibrin Gels: the Role of Fibroblasts and Angiopoietin-1 Microvascular Research. Sep, 2003 | Pubmed ID: 12935768 Notch Activation During Endothelial Cell Network Formation in Vitro Targets the Basic HLH Transcription Factor HESR-1 and Downregulates VEGFR-2/KDR Expression Microvascular Research. Nov, 2002 | Pubmed ID: 12453432 Integration of the Non-genomic and Genomic Actions of Estrogen. Membrane-initiated Signaling by Steroid to Transcription and Cell Biology The Journal of Biological Chemistry. Dec, 2002 | Pubmed ID: 12372818 Endothelial Cells Stimulate T Cell NFAT Nuclear Translocation in the Presence of Cyclosporin A: Involvement of the Wnt/glycogen Synthase Kinase-3 Beta Pathway Journal of Immunology (Baltimore, Md. : 1950). Oct, 2002 | Pubmed ID: 12244165 B7-H1 is Expressed by Human Endothelial Cells and Suppresses T Cell Cytokine Synthesis Journal of Immunology (Baltimore, Md. : 1950). Oct, 2002 | Pubmed ID: 12244148 Identification of Endothelial Cell Genes Expressed in an in Vitro Model of Angiogenesis: Induction of ESM-1, (beta)ig-h3, and NrCAM Microvascular Research. Mar, 2002 | Pubmed ID: 11866539 אופטימליים הפיברין ג'ל ביד Assay לחקר אנגיוגנזה Martin N. Nakatsu1, Jaeger Davis1, Christopher C.W. Hughes1 1Department of Molecular Biology and Biochemistry, University of California, Irvine (UCI) JoVE 186 Biologia כריסטופר יוז: במודל חוץ גופית לחקר אנגיוגנזה (ראיון) Christopher C.W. Hughes1 1Department of Molecular Biology and Biochemistry, University of California, Irvine (UCI) JoVE 175 Biologia בידוד של האדם תאים עורק טבורי האנדותל (HUVEC) Jaeger Davis1, Steve P. Crampton1, Christopher C.W. Hughes1 1Department of Molecular Biology and Biochemistry, University of California, Irvine (UCI) JoVE 183 Biologia
אופטימליים הפיברין ג'ל ביד Assay לחקר אנגיוגנזה Martin N. Nakatsu1, Jaeger Davis1, Christopher C.W. Hughes1 1Department of Molecular Biology and Biochemistry, University of California, Irvine (UCI) JoVE 186 Biologia
כריסטופר יוז: במודל חוץ גופית לחקר אנגיוגנזה (ראיון) Christopher C.W. Hughes1 1Department of Molecular Biology and Biochemistry, University of California, Irvine (UCI) JoVE 175 Biologia
בידוד של האדם תאים עורק טבורי האנדותל (HUVEC) Jaeger Davis1, Steve P. Crampton1, Christopher C.W. Hughes1 1Department of Molecular Biology and Biochemistry, University of California, Irvine (UCI) JoVE 183 Biologia