Christopher E. Turner Department of Cell & Developmental Biology SUNY Upstate Medical University Biography Publications Institution JoVE Articles Christopher E. Turner has not added a biography. If you are Christopher E. Turner and would like to personalize this page please email our Author Liaison for assistance. Publications Paxillin Inhibits HDAC6 to Regulate Microtubule Acetylation, Golgi Structure, and Polarized Migration The Journal of Cell Biology. Aug, 2014 | Pubmed ID: 25070956 The Focal Adhesion-localized CdGAP Regulates Matrix Rigidity Sensing and Durotaxis PloS One. 2014 | Pubmed ID: 24632816 LIM Domains Target Actin Regulators Paxillin and Zyxin to Sites of Stress Fiber Strain PloS One. 2013 | Pubmed ID: 23990882 Paxillin Kinase Linker (PKL) Regulates Vav2 Signaling During Cell Spreading and Migration Molecular Biology of the Cell. Jun, 2013 | Pubmed ID: 23615439 Diverse Roles for the Paxillin Family of Proteins in Cancer Genes & Cancer. May, 2012 | Pubmed ID: 23226574 Beta2-adaptin Binds Actopaxin and Regulates Cell Spreading, Migration and Matrix Degradation PloS One. 2012 | Pubmed ID: 23056266 Actopaxin (α-parvin) Phosphorylation is Required for Matrix Degradation and Cancer Cell Invasion The Journal of Biological Chemistry. Oct, 2012 | Pubmed ID: 22955285 CdGAP Regulates Cell Migration and Adhesion Dynamics in Two-and Three-dimensional Matrix Environments Cytoskeleton (Hoboken, N.J.). Sep, 2012 | Pubmed ID: 22907917 Paxillin and Hic-5 Interaction with Vinculin is Differentially Regulated by Rac1 and RhoA PloS One. 2012 | Pubmed ID: 22629471 Hic-5 Promotes Invadopodia Formation and Invasion During TGF-β-induced Epithelial-mesenchymal Transition The Journal of Cell Biology. Apr, 2012 | Pubmed ID: 22529104 LNK (SH2B3) is a Key Regulator of Integrin Signaling in Endothelial Cells and Targets α-parvin to Control Cell Adhesion and Migration FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jun, 2012 | Pubmed ID: 22441983 Distinct Roles for Paxillin and Hic-5 in Regulating Breast Cancer Cell Morphology, Invasion, and Metastasis Molecular Biology of the Cell. Feb, 2011 | Pubmed ID: 21148292 The Cell Adhesion-associated Protein Git2 Regulates Morphogenetic Movements During Zebrafish Embryonic Development Developmental Biology. Jan, 2011 | Pubmed ID: 21034731 Emerging Role of Paxillin-PKL in Regulation of Cell Adhesion, Polarity and Migration Cell Adhesion & Migration. Jul-Sep, 2010 | Pubmed ID: 20372092 Paxillin-kinase-linker Tyrosine Phosphorylation Regulates Directional Cell Migration Molecular Biology of the Cell. Nov, 2009 | Pubmed ID: 19776348 FAK Engages Multiple Pathways to Maintain Survival of Fibroblasts and Epithelia: Differential Roles for Paxillin and P130Cas Journal of Cell Science. Feb, 2009 | Pubmed ID: 19126677 Cross Talk Between Paxillin and Rac is Critical for Mediation of Barrier-protective Effects by Oxidized Phospholipids American Journal of Physiology. Lung Cellular and Molecular Physiology. Oct, 2008 | Pubmed ID: 18676874 Paxillin Comes of Age Journal of Cell Science. Aug, 2008 | Pubmed ID: 18650496 Hic-5 Promotes the Hypertrophic Scar Myofibroblast Phenotype by Regulating the TGF-beta1 Autocrine Loop The Journal of Investigative Dermatology. Oct, 2008 | Pubmed ID: 18401422 Paxillin-dependent Stimulation of Microtubule Catastrophes at Focal Adhesion Sites Journal of Cell Science. Jan, 2008 | Pubmed ID: 18187451 TGF-beta1 Slows the Growth of Pathogenic Myofibroblasts Through a Mechanism Requiring the Focal Adhesion Protein, Hic-5 The Journal of Investigative Dermatology. Feb, 2008 | Pubmed ID: 17671518 Hic-5 Contributes to Epithelial-mesenchymal Transformation Through a RhoA/ROCK-dependent Pathway Journal of Cellular Physiology. Jun, 2007 | Pubmed ID: 17299801 CdGAP Associates with Actopaxin to Regulate Integrin-dependent Changes in Cell Morphology and Motility Current Biology : CB. Jul, 2006 | Pubmed ID: 16860736 Paxillin is Essential for PTP-PEST-dependent Regulation of Cell Spreading and Motility: a Role for Paxillin Kinase Linker Journal of Cell Science. Dec, 2005 | Pubmed ID: 16317044 Regulation of Paxillin Family Members During Epithelial-mesenchymal Transformation: a Putative Role for Paxillin Delta Journal of Cell Science. Oct, 2005 | Pubmed ID: 16219691 Tyrosine-phosphorylated Hic-5 Inhibits Epidermal Growth Factor-induced Lamellipodia Formation Experimental Cell Research. Nov, 2005 | Pubmed ID: 16183059 Src and FAK Kinases Cooperate to Phosphorylate Paxillin Kinase Linker, Stimulate Its Focal Adhesion Localization, and Regulate Cell Spreading and Protrusiveness Molecular Biology of the Cell. Sep, 2005 | Pubmed ID: 16000375 Actopaxin Interacts with TESK1 to Regulate Cell Spreading on Fibronectin The Journal of Biological Chemistry. Jun, 2005 | Pubmed ID: 15817463 The Integrin-linked Kinase Regulates Cell Morphology and Motility in a Rho-associated Kinase-dependent Manner The Journal of Biological Chemistry. Dec, 2004 | Pubmed ID: 15485819 Paxillin: Adapting to Change Physiological Reviews. Oct, 2004 | Pubmed ID: 15383653 Phosphorylation of Actopaxin Regulates Cell Spreading and Migration The Journal of Cell Biology. Sep, 2004 | Pubmed ID: 15353548 Vinculin Modulation of Paxillin-FAK Interactions Regulates ERK to Control Survival and Motility The Journal of Cell Biology. May, 2004 | Pubmed ID: 15138291 EphB1-mediated Cell Migration Requires the Phosphorylation of Paxillin at Tyr-31/Tyr-118 The Journal of Biological Chemistry. Jul, 2004 | Pubmed ID: 15107421 Integrin-linked Kinase: a Possible Role in Scar Contracture Annals of Plastic Surgery. Feb, 2004 | Pubmed ID: 14745274 FAK-Src Signalling Through Paxillin, ERK and MLCK Regulates Adhesion Disassembly Nature Cell Biology. Feb, 2004 | Pubmed ID: 14743221 Tension Development During Contractile Stimulation of Smooth Muscle Requires Recruitment of Paxillin and Vinculin to the Membrane American Journal of Physiology. Cell Physiology. Feb, 2004 | Pubmed ID: 14576084 Expression of Non-phosphorylatable Paxillin Mutants in Canine Tracheal Smooth Muscle Inhibits Tension Development The Journal of Physiology. Nov, 2003 | Pubmed ID: 12949231 RNF5, a RING Finger Protein That Regulates Cell Motility by Targeting Paxillin Ubiquitination and Altered Localization Molecular and Cellular Biology. Aug, 2003 | Pubmed ID: 12861019 Crk Associates with a Multimolecular Paxillin/GIT2/beta-PIX Complex and Promotes Rac-dependent Relocalization of Paxillin to Focal Contacts Molecular Biology of the Cell. Jul, 2003 | Pubmed ID: 12857867 Extracellular Signal-regulated Kinase Mediates Phosphorylation of Tropomyosin-1 to Promote Cytoskeleton Remodeling in Response to Oxidative Stress: Impact on Membrane Blebbing Molecular Biology of the Cell. Apr, 2003 | Pubmed ID: 12686598 Ca2+-dependent Localization of Integrin-linked Kinase to Cell Junctions in Differentiating Keratinocytes The Journal of Biological Chemistry. Mar, 2003 | Pubmed ID: 12547824 Paxillin-dependent Paxillin Kinase Linker and P21-activated Kinase Localization to Focal Adhesions Involves a Multistep Activation Pathway Molecular Biology of the Cell. May, 2002 | Pubmed ID: 12006652 Roles for the Tubulin- and PTP-PEST-binding Paxillin LIM Domains in Cell Adhesion and Motility The International Journal of Biochemistry & Cell Biology. Jul, 2002 | Pubmed ID: 11950600 Actopaxin is Phosphorylated During Mitosis and is a Substrate for Cyclin B1/cdc2 Kinase The Biochemical Journal. Apr, 2002 | Pubmed ID: 11931650 Epidermal Growth Factor Stimulates Serine/threonine Phosphorylation of the Focal Adhesion Protein Paxillin in a MEK-dependent Manner in Normal Rat Kidney Cells Journal of Cellular Physiology. Apr, 2002 | Pubmed ID: 11920684 A Fragment of Paxillin Binds the Alpha 4 Integrin Cytoplasmic Domain (tail) and Selectively Inhibits Alpha 4-mediated Cell Migration The Journal of Biological Chemistry. Jun, 2002 | Pubmed ID: 11919182 The Paxillin LD Motifs FEBS Letters. Feb, 2002 | Pubmed ID: 11911889 The Adaptor Protein Paxillin is Essential for Normal Development in the Mouse and is a Critical Transducer of Fibronectin Signaling Molecular and Cellular Biology. Feb, 2002 | Pubmed ID: 11784865 Molecular Dissection of Actopaxin-integrin-linked Kinase-Paxillin Interactions and Their Role in Subcellular Localization The Journal of Biological Chemistry. Jan, 2002 | Pubmed ID: 11694518 A Simplified System for Evaluating Cell Mechanosensing and Durotaxis In Vitro Gregory J. Goreczny1, Duncan B. Wormer1, Christopher E. Turner1 1Department of Cell & Developmental Biology, SUNY Upstate Medical University JoVE 52949 Biologia
A Simplified System for Evaluating Cell Mechanosensing and Durotaxis In Vitro Gregory J. Goreczny1, Duncan B. Wormer1, Christopher E. Turner1 1Department of Cell & Developmental Biology, SUNY Upstate Medical University JoVE 52949 Biologia