Dana Faratian Breakthrough Breast Cancer Research Unit University of Edinburgh Biography Publications Institution JoVE Articles Dana Faratian has not added a biography. If you are Dana Faratian and would like to personalize this page please email our Author Liaison for assistance. Publications Feedforward and Feedback Regulation of the MAPK and PI3K Oscillatory Circuit in Breast Cancer Cellular Signalling. Jan, 2013 | Pubmed ID: 23000339 Transcript and Protein Profiling Identify Signaling, Growth Arrest, Apoptosis and NFκB-survival Signatures Following GnRH Receptor Activation Endocrine-related Cancer. Nov, 2012 | Pubmed ID: 23202794 Diversity of Matriptase Expression Level and Function in Breast Cancer PloS One. 2012 | Pubmed ID: 22514623 HER2 Expression in Ovarian Carcinoma: Caution and Complexity in Biomarker Analysis Journal of Clinical Pathology. Jul, 2012 | Pubmed ID: 22412045 The Use of Automated Quantitative Analysis to Evaluate Epithelial-to-mesenchymal Transition Associated Proteins in Clear Cell Renal Cell Carcinoma PloS One. 2012 | Pubmed ID: 22363672 Validation of Activated Caspase-3 Antibody Staining As a Marker of Apoptosis in Breast Cancer Histopathology. Jan, 2012 | Pubmed ID: 22168172 Features of the Reversible Sensitivity-resistance Transition in PI3K/PTEN/AKT Signalling Network After HER2 Inhibition Cellular Signalling. Feb, 2012 | Pubmed ID: 21996585 Model-based Global Sensitivity Analysis As Applied to Identification of Anti-cancer Drug Targets and Biomarkers of Drug Resistance in the ErbB2/3 Network European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences. Nov, 2011 | Pubmed ID: 22085636 GnRH Receptor Activation Competes at a Low Level with Growth Signaling in Stably Transfected Human Breast Cell Lines BMC Cancer. 2011 | Pubmed ID: 22051164 Sprouty 2 is an Independent Prognostic Factor in Breast Cancer and May Be Useful in Stratifying Patients for Trastuzumab Therapy PloS One. 2011 | Pubmed ID: 21909357 Co-expression of SNAIL and TWIST Determines Prognosis in Estrogen Receptor-positive Early Breast Cancer Patients Breast Cancer Research and Treatment. Jul, 2011 | Pubmed ID: 21796367 Two Possible Mechanisms of Epithelial to Mesenchymal Transition in Invasive Ductal Breast Cancer Clinical & Experimental Metastasis. Dec, 2011 | Pubmed ID: 21789718 Trastuzumab and Pertuzumab Produce Changes in Morphology and Estrogen Receptor Signaling in Ovarian Cancer Xenografts Revealing New Treatment Strategies Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jul, 2011 | Pubmed ID: 21571868 What Can Molecular Pathology Contribute to the Management of Renal Cell Carcinoma? Nature Reviews. Urology. May, 2011 | Pubmed ID: 21487387 Phosphoprotein Pathway Profiling of Ovarian Carcinoma for the Identification of Potential New Targets for Therapy European Journal of Cancer (Oxford, England : 1990). Jun, 2011 | Pubmed ID: 21334202 Compensatory Effects in the PI3K/PTEN/AKT Signaling Network Following Receptor Tyrosine Kinase Inhibition Cellular Signalling. Feb, 2011 | Pubmed ID: 20951800 Breast Cancer Research and Treatment. Feb, 2011 | Pubmed ID: 20358279 Higher Incidence of Isolated Brain Metastases in Ovarian Cancer Patients with Previous Early Breast Cancer International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society. Dec, 2010 | Pubmed ID: 21370594 Systems Pathology Breast Cancer Research : BCR. 2010 | Pubmed ID: 21172088 Tyrosine Phosphorylation Profiling Reveals the Signaling Network Characteristics of Basal Breast Cancer Cells Cancer Research. Nov, 2010 | Pubmed ID: 20861192 Cancer Systems Biology Methods in Molecular Biology (Clifton, N.J.). 2010 | Pubmed ID: 20824475 Dynamic Changes in Gene Expression in Vivo Predict Prognosis of Tamoxifen-treated Patients with Breast Cancer Breast Cancer Research : BCR. 2010 | Pubmed ID: 20569502 Pertuzumab for the Treatment of Ovarian Cancer Expert Opinion on Biological Therapy. Jul, 2010 | Pubmed ID: 20465533 Automated Image Analysis for High-throughput Quantitative Detection of ER and PR Expression Levels in Large-scale Clinical Studies: the TEAM Trial Experience Histopathology. Nov, 2009 | Pubmed ID: 19912364 The Importance of Growth Factors and Steroid Hormones in Ovarian Cancer Onkologie. Nov, 2009 | Pubmed ID: 19887864 How Can Systems Pathology Help Us Personalize Cancer Therapy? Discovery Medicine. Aug, 2009 | Pubmed ID: 19788873 Modulation of HER3 is a Marker of Dynamic Cell Signaling in Ovarian Cancer: Implications for Pertuzumab Sensitivity Molecular Cancer Research : MCR. Sep, 2009 | Pubmed ID: 19737968 Residual Breast Cancers After Conventional Therapy Display Mesenchymal As Well As Tumor-initiating Features Proceedings of the National Academy of Sciences of the United States of America. Aug, 2009 | Pubmed ID: 19666588 Systems Biology Reveals New Strategies for Personalizing Cancer Medicine and Confirms the Role of PTEN in Resistance to Trastuzumab Cancer Research. Aug, 2009 | Pubmed ID: 19638581 Systems Pathology--taking Molecular Pathology into a New Dimension Nature Reviews. Clinical Oncology. Aug, 2009 | Pubmed ID: 19581910 Rapid Screening of Tissue Microarrays for Her-2 Fluorescence in Situ Hybridization Testing is an Accurate, Efficient and Economic Method of Providing an Entirely in Situ Hybridization-based Her-2 Testing Service Histopathology. Mar, 2009 | Pubmed ID: 19309394 PPM1D is a Potential Therapeutic Target in Ovarian Clear Cell Carcinomas Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Apr, 2009 | Pubmed ID: 19293255 Pleural Wegener's Granulomatosis: a Rare Presentation Histopathology. Feb, 2009 | Pubmed ID: 19236522 Membranous and Cytoplasmic Staining of Ki67 is Associated with HER2 and ER Status in Invasive Breast Carcinoma Histopathology. Jan, 2009 | Pubmed ID: 19207951 Diesel Exhaust Inhalation Increases Thrombus Formation in Man European Heart Journal. Dec, 2008 | Pubmed ID: 18952612 Dynamic Computational Modeling in the Search for Better Breast Cancer Drug Therapy Pharmacogenomics. Dec, 2007 | Pubmed ID: 18086005 DCIS and Aromatase Inhibitors The Journal of Steroid Biochemistry and Molecular Biology. Aug-Sep, 2007 | Pubmed ID: 17604618 Estrogen-independent Proliferation is Present in Estrogen-receptor HER2-positive Primary Breast Cancer After Neoadjuvant Letrozole Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Jul, 2006 | Pubmed ID: 16754938 The Use of Reverse Phase Protein Arrays (RPPA) to Explore Protein Expression Variation within Individual Renal Cell Cancers Fiach C. O'Mahony1, Jyoti Nanda1, Alexander Laird1, Peter Mullen2, Helen Caldwell3, Ian M. Overton4, Lel Eory4, Marie O'Donnell1,5, Dana Faratian6, Thomas Powles7, David J. Harrison1,2, Grant D. Stewart1 1Edinburgh Urological Cancer Group, University of Edinburgh, 2School of Medicine, University of St Andrews, 3Division of Pathology, University of Edinburgh, 4MRC Human Genetics Unit, MRC IGMM, University of Edinburgh, 5Department of Pathology, Western General Hospital, 6Breakthrough Breast Cancer Research Unit, University of Edinburgh, 7St Bartholomew's Cancer Institute, Experimental Cancer Medicine Centre, Queen Mary University of London JoVE 50221 Medicina Heterogeneity Mapping of Protein Expression in Tumors using Quantitative Immunofluorescence Dana Faratian1, Jason Christiansen2, Mark Gustavson2, Christine Jones2, Christopher Scott2, InHwa Um1, David J. Harrison1 1Division of Pathology, University of Edinburgh, 2HistoRx Inc. JoVE 3334 Medicina
The Use of Reverse Phase Protein Arrays (RPPA) to Explore Protein Expression Variation within Individual Renal Cell Cancers Fiach C. O'Mahony1, Jyoti Nanda1, Alexander Laird1, Peter Mullen2, Helen Caldwell3, Ian M. Overton4, Lel Eory4, Marie O'Donnell1,5, Dana Faratian6, Thomas Powles7, David J. Harrison1,2, Grant D. Stewart1 1Edinburgh Urological Cancer Group, University of Edinburgh, 2School of Medicine, University of St Andrews, 3Division of Pathology, University of Edinburgh, 4MRC Human Genetics Unit, MRC IGMM, University of Edinburgh, 5Department of Pathology, Western General Hospital, 6Breakthrough Breast Cancer Research Unit, University of Edinburgh, 7St Bartholomew's Cancer Institute, Experimental Cancer Medicine Centre, Queen Mary University of London JoVE 50221 Medicina
Heterogeneity Mapping of Protein Expression in Tumors using Quantitative Immunofluorescence Dana Faratian1, Jason Christiansen2, Mark Gustavson2, Christine Jones2, Christopher Scott2, InHwa Um1, David J. Harrison1 1Division of Pathology, University of Edinburgh, 2HistoRx Inc. JoVE 3334 Medicina