David A. Copland Academic Unit of Ophthalmology, Translational Health Sciences University of Bristol Biography Publications Institution JoVE Articles David A. Copland has not added a biography. If you are David A. Copland and would like to personalize this page please email our Author Liaison for assistance. Publications Unravelling the Therapeutic Potential of IL-33 for Atrophic AMD Eye (London, England). Sep, 2021 | Pubmed ID: 34531552 Quantitative Assessment of Experimental Ocular Inflammatory Disease Frontiers in Immunology. 2021 | Pubmed ID: 34220797 Engineering Adeno-associated Viral Vectors to Evade Innate Immune and Inflammatory Responses Science Translational Medicine. 02, 2021 | Pubmed ID: 33568518 Cellular Senescence in the Aging Retina and Developments of Senotherapies for Age-related Macular Degeneration Journal of Neuroinflammation. Jan, 2021 | Pubmed ID: 33482879 Treatment with Interleukin-33 is Non-toxic and Protects Retinal Pigment Epithelium in an Ageing Model of Outer Retinal Degeneration Journal of Cellular and Molecular Medicine. 11, 2020 | Pubmed ID: 33079455 Treatment of Diabetic Retinopathy Through Neuropeptide Y-mediated Enhancement of Neurovascular Microenvironment Journal of Cellular and Molecular Medicine. 04, 2020 | Pubmed ID: 32141716 Intravenous Indocyanine Green Dye is Insufficient for Robust Immune Cell Labelling in the Human Retina PloS One. 2020 | Pubmed ID: 32053618 Gene Therapy for Glaucoma by Ciliary Body Aquaporin 1 Disruption Using CRISPR-Cas9 Molecular Therapy : the Journal of the American Society of Gene Therapy. 03, 2020 | Pubmed ID: 31981492 Single Eye MRNA-Seq Reveals Normalisation of the Retinal Microglial Transcriptome Following Acute Inflammation Frontiers in Immunology. 2019 | Pubmed ID: 31993055 Modelling Macular Edema: The Effect of IL-6 and IL-6R Blockade on Human Blood-Retinal Barrier Integrity In Vitro Translational Vision Science & Technology. Sep, 2019 | Pubmed ID: 31667008 Corrigendum to "Restoring Retinal Neurovascular Health Via Substance P" [Exp. Cell Res. (2019)] Experimental Cell Research. Sep, 2019 | Pubmed ID: 31284947 Restoring Retinal Neurovascular Health Via Substance P Experimental Cell Research. 07, 2019 | Pubmed ID: 30995434 Müller Cells Stabilize Microvasculature Through Hypoxic Preconditioning Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 2019 | Pubmed ID: 30921506 The Bromodomain and Extra-Terminal Protein Inhibitor OTX015 Suppresses T Helper Cell Proliferation and Differentiation Current Molecular Medicine. 2018 | Pubmed ID: 30683020 A Perspective of AMD Through the Eyes of Immunology Investigative Ophthalmology & Visual Science. 03, 2018 | Pubmed ID: 30025105 Re-programming Immunosurveillance in Persistent Non-infectious Ocular Inflammation Progress in Retinal and Eye Research. 07, 2018 | Pubmed ID: 29530739 Soluble CD200 Correlates With Interleukin-6 Levels in Sera of COPD Patients: Potential Implication of the CD200/CD200R Axis in the Disease Course Lung. 02, 2017 | Pubmed ID: 27864635 Interleukin-33 Regulates Tissue Remodelling and Inhibits Angiogenesis in the Eye The Journal of Pathology. Jan, 2017 | Pubmed ID: 27701734 An Anti-TNF-α Antibody Mimetic to Treat Ocular Inflammation Scientific Reports. 11, 2016 | Pubmed ID: 27874029 Pleiotropic Action of CpG-ODN on Endothelium and Macrophages Attenuates Angiogenesis Through Distinct Pathways Scientific Reports. 08, 2016 | Pubmed ID: 27558877 Impairing Autophagy in Retinal Pigment Epithelium Leads to Inflammasome Activation and Enhanced Macrophage-mediated Angiogenesis Scientific Reports. Feb, 2016 | Pubmed ID: 26847702 Multimodal Analysis of Ocular Inflammation Using the Endotoxin-induced Uveitis Mouse Model Disease Models & Mechanisms. Apr, 2016 | Pubmed ID: 26794131 A Simple Method for in Vivo Labelling of Infiltrating Leukocytes in the Mouse Retina Using Indocyanine Green Dye Disease Models & Mechanisms. Nov, 2015 | Pubmed ID: 26398933 Role of Interleukin 33/ST2 Axis in the Immune-mediated Pathogenesis of Age-related Macular Degeneration Lancet (London, England). Feb, 2015 | Pubmed ID: 26312920 A Novel Pathogenic RBP-3 Peptide Reveals Epitope Spreading in Persistent Experimental Autoimmune Uveoretinitis Immunology. Oct, 2015 | Pubmed ID: 26152845 IL-4 Regulates Specific Arg-1(+) Macrophage SFlt-1-mediated Inhibition of Angiogenesis The American Journal of Pathology. Aug, 2015 | Pubmed ID: 26079814 Homeostatic Regulation of T Cell Trafficking by a B Cell-derived Peptide is Impaired in Autoimmune and Chronic Inflammatory Disease Nature Medicine. May, 2015 | Pubmed ID: 25894827 Glucocorticoid-resistant Th17 Cells Are Selectively Attenuated by Cyclosporine A Proceedings of the National Academy of Sciences of the United States of America. Mar, 2015 | Pubmed ID: 25775512 TNFα Regulates SIRT1 Cleavage During Ocular Autoimmune Disease The American Journal of Pathology. May, 2015 | Pubmed ID: 25770475 Activated Adult Microglia Influence Retinal Progenitor Cell Proliferation and Differentiation Toward Recoverin-expressing Neuron-like Cells in a Co-culture Model Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fur Klinische Und Experimentelle Ophthalmologie. Jul, 2015 | Pubmed ID: 25680876 Local Targeting of the CD200-CD200R Axis Does Not Promote Corneal Graft Survival Experimental Eye Research. Jan, 2015 | Pubmed ID: 25450061 Tissue-Resident Exhausted Effector Memory CD8+ T Cells Accumulate in the Retina During Chronic Experimental Autoimmune Uveoretinitis Journal of Immunology (Baltimore, Md. : 1950). Apr, 2014 | Pubmed ID: 24740509 CD200R Signaling Inhibits Pro-angiogenic Gene Expression by Macrophages and Suppresses Choroidal Neovascularization Scientific Reports. 2013 | Pubmed ID: 24170042 Myeloid Cells Expressing VEGF and Arginase-1 Following Uptake of Damaged Retinal Pigment Epithelium Suggests Potential Mechanism That Drives the Onset of Choroidal Angiogenesis in Mice PloS One. 2013 | Pubmed ID: 23977372 Environmental Conditioning in the Control of Macrophage Thrombospondin-1 Production Scientific Reports. 2012 | Pubmed ID: 22803005 Therapeutic Dosing of Fingolimod (FTY720) Prevents Cell Infiltration, Rapidly Suppresses Ocular Inflammation, and Maintains the Blood-ocular Barrier The American Journal of Pathology. Feb, 2012 | Pubmed ID: 22119714 TNFR1 Signalling is a Critical Checkpoint for Developing Macrophages That Control of T-cell Proliferation Immunology. Nov, 2010 | Pubmed ID: 20518824 TNFR1-dependent Regulation of Myeloid Cell Function in Experimental Autoimmune Uveoretinitis Journal of Immunology (Baltimore, Md. : 1950). Aug, 2009 | Pubmed ID: 19635911 Analysis of Retinal Cellular Infiltrate in Experimental Autoimmune Uveoretinitis Reveals Multiple Regulatory Cell Populations Journal of Autoimmunity. Dec, 2008 | Pubmed ID: 18838247 The Dynamics of Leukocyte Infiltration in Experimental Autoimmune Uveoretinitis Progress in Retinal and Eye Research. Sep, 2008 | Pubmed ID: 18723108 The B Subunit of Escherichia Coli Heat-labile Enterotoxin Inhibits Th1 but Not Th17 Cell Responses in Established Experimental Autoimmune Uveoretinitis Investigative Ophthalmology & Visual Science. Sep, 2008 | Pubmed ID: 18469197 Monoclonal Antibody-mediated CD200 Receptor Signaling Suppresses Macrophage Activation and Tissue Damage in Experimental Autoimmune Uveoretinitis The American Journal of Pathology. Aug, 2007 | Pubmed ID: 17600119 Mapping Immune Responses to MRBP-3 1-16 Peptide with Altered Peptide Ligands Investigative Ophthalmology & Visual Science. May, 2006 | Pubmed ID: 16639012 पोस्ट-इन्फेक्शियस यूवाइटिस के लिए एक मॉडल के रूप में प्राइमेड माइकोबैक्टीरियल यूवाइटिस (पीएमयू) Sarah John1, Oliver H. Bell2, Leslie Wilson1, David A. Copland2, Kathryn L. Pepple1 1Department of Ophthalmology, University of Washington, 2Academic Unit of Ophthalmology, Translational Health Sciences, University of Bristol JoVE 62925 Immunologia e infezioni
पोस्ट-इन्फेक्शियस यूवाइटिस के लिए एक मॉडल के रूप में प्राइमेड माइकोबैक्टीरियल यूवाइटिस (पीएमयू) Sarah John1, Oliver H. Bell2, Leslie Wilson1, David A. Copland2, Kathryn L. Pepple1 1Department of Ophthalmology, University of Washington, 2Academic Unit of Ophthalmology, Translational Health Sciences, University of Bristol JoVE 62925 Immunologia e infezioni