David Hawke Proteomics Facility, Department of Pathology University of Texas MD Anderson Cancer Center Biography Publications Institution JoVE Articles David Hawke has not added a biography. If you are David Hawke and would like to personalize this page please email our Author Liaison for assistance. Publications C-Terminal Protein Characterization by Mass Spectrometry Using Combined Micro Scale Liquid and Solid-Phase Derivatization Journal of Biomolecular Techniques : JBT. Apr, 2013 | Pubmed ID: 23543807 Lack of IGb3 and Isoglobo-Series Glycosphingolipids in Pig Organs Used for Xenotransplantation: Implications for Natural Killer T-Cell Biology Journal of Carbohydrate Chemistry. Jan, 2013 | Pubmed ID: 23378701 Endothelial Cells Promote the Colorectal Cancer Stem Cell Phenotype Through a Soluble Form of Jagged-1 Cancer Cell. Feb, 2013 | Pubmed ID: 23375636 Binding Partners for Curcumin in Human Schwannoma Cells: Biologic Implications Bioorganic & Medicinal Chemistry. Feb, 2013 | Pubmed ID: 23294827 Glioma Pathogenesis-related Protein 1 Induces Prostate Cancer Cell Death Through Hsc70-mediated Suppression of AURKA and TPX2 Molecular Oncology. Dec, 2012 | Pubmed ID: 23333597 Phosphopeptide Charakterisierung Von Massenspektrometrie Mit Umkehrphasen-Unterstützungen Für Festphasen-β-Eliminierung/Michael-Addition Journal of Biomolecular Techniques : JBT. Jul, 2012 | Pubmed ID: 22951960 PKM2 Phosphorylates Histone H3 and Promotes Gene Transcription and Tumorigenesis Cell. Aug, 2012 | Pubmed ID: 22901803 Characterization of a Human 12/15-lipoxygenase Promoter Variant Associated with Atherosclerosis Identifies Vimentin As a Promoter Binding Protein PloS One. 2012 | Pubmed ID: 22879973 AKT-dependent Phosphorylation of Niban Regulates Nucleophosmin- and MDM2-mediated P53 Stability and Cell Apoptosis EMBO Reports. Jun, 2012 | Pubmed ID: 22510990 Ras-induced and Extracellular Signal-regulated Kinase 1 and 2 Phosphorylation-dependent Isomerization of Protein Tyrosine Phosphatase (PTP)-PEST by PIN1 Promotes FAK Dephosphorylation by PTP-PEST Molecular and Cellular Biology. Nov, 2011 | Pubmed ID: 21876001 PMLRARα Binds to Fas and Suppresses Fas-mediated Apoptosis Through Recruiting C-FLIP in Vivo Blood. Sep, 2011 | Pubmed ID: 21803845 Identification and Validation of SRC and Phospho-SRC Family Proteins in Circulating Mononuclear Cells As Novel Biomarkers for Pancreatic Cancer Translational Oncology. 2011 | Pubmed ID: 21461171 Die ABRF Proteomics Research Group-Studien: Pädagogische Übungen Für Qualitative Und Quantitative Proteomic Analysen Proteomics. Apr, 2011 | Pubmed ID: 21394914 Fatty Acid Synthase Phosphorylation: a Novel Therapeutic Target in HER2-overexpressing Breast Cancer Cells Breast Cancer Research : BCR. 2010 | Pubmed ID: 21080941 Evaluation of Changes in Serum Protein Profiles During Neoadjuvant Chemotherapy in HER2-positive Breast Cancer Using an LC-MALDI-TOF/MS Procedure Proteomics. Oct, 2010 | Pubmed ID: 20827732 From Combinatorial Peptide Selection to Drug Prototype (I): Targeting the Vascular Endothelial Growth Factor Receptor Pathway Proceedings of the National Academy of Sciences of the United States of America. Mar, 2010 | Pubmed ID: 20190181 Chain Termination and Inhibition of Mammalian Poly(A) Polymerase by Modified ATP Analogues Biochemical Pharmacology. Mar, 2010 | Pubmed ID: 19814999 EGF-induced ERK Activation Promotes CK2-mediated Disassociation of Alpha-Catenin from Beta-Catenin and Transactivation of Beta-Catenin Molecular Cell. Nov, 2009 | Pubmed ID: 19941816 FAK Phosphorylation by ERK Primes Ras-induced Tyrosine Dephosphorylation of FAK Mediated by PIN1 and PTP-PEST Molecular Cell. Jul, 2009 | Pubmed ID: 19595712 Caspase-10-mediated Heat Shock Protein 90 Beta Cleavage Promotes UVB Irradiation-induced Cell Apoptosis Molecular and Cellular Biology. Jul, 2009 | Pubmed ID: 19380486 Immunologic Glycosphingolipidomics and NKT Cell Development in Mouse Thymus Journal of Proteome Research. Jun, 2009 | Pubmed ID: 19284783 Stimulation of Lung Innate Immunity Protects Against Lethal Pneumococcal Pneumonia in Mice American Journal of Respiratory and Critical Care Medicine. Jun, 2008 | Pubmed ID: 18388354 Proteomics-based Identification of Proteins Secreted in Apical Surface Fluid of Squamous Metaplastic Human Tracheobronchial Epithelial Cells Cultured by Three-dimensional Organotypic Air-liquid Interface Method Cancer Research. Jul, 2007 | Pubmed ID: 17638865 Phosphorylation of Beta-catenin by AKT Promotes Beta-catenin Transcriptional Activity The Journal of Biological Chemistry. Apr, 2007 | Pubmed ID: 17287208 A Method for the Isolation of Blocked N-terminal Peptides Analytical Biochemistry. Feb, 2007 | Pubmed ID: 17188638 Tyrosine Phosphorylation Controls PCNA Function Through Protein Stability Nature Cell Biology. Dec, 2006 | Pubmed ID: 17115032 Proteomic Analysis of Nipple Aspirate Fluid from Women with Early-stage Breast Cancer Using Isotope-coded Affinity Tags and Tandem Mass Spectrometry Reveals Differential Expression of Vitamin D Binding Protein BMC Cancer. 2006 | Pubmed ID: 16542425 Serum Amyloid A As a Tumor Marker in Sera of Nude Mice with Orthotopic Human Pancreatic Cancer and in Plasma of Patients with Pancreatic Cancer International Journal of Oncology. Nov, 2005 | Pubmed ID: 16211233 Set1-Methyltransferase Lehnt Ipl1-Aurora-Kinase-Funktionen Im Chromosom Rassentrennung Cell. Sep, 2005 | Pubmed ID: 16143104 A Role for Cell-cycle-regulated Histone H3 Lysine 56 Acetylation in the DNA Damage Response Nature. Jul, 2005 | Pubmed ID: 16015338 Diagnostic Protein Discovery Using Liquid Chromatography/mass Spectrometry for Proteolytic Peptide Targeting Rapid Communications in Mass Spectrometry : RCM. 2005 | Pubmed ID: 15915451 Developing an Understanding of Proteomics: an Introduction to Biological Mass Spectrometry Cancer Investigation. 2005 | Pubmed ID: 15779868 A Circulating Ligand for Galectin-3 is a Haptoglobin-related Glycoprotein Elevated in Individuals with Colon Cancer Gastroenterology. Sep, 2004 | Pubmed ID: 15362030 Human P32, Interacts with B Subunit of the CCAAT-binding Factor, CBF/NF-Y, and Inhibits CBF-mediated Transcription Activation in Vitro Nucleic Acids Research. 2004 | Pubmed ID: 15243141 Tumor Suppressor ARF Degrades B23, a Nucleolar Protein Involved in Ribosome Biogenesis and Cell Proliferation Molecular Cell. Nov, 2003 | Pubmed ID: 14636574 Expression and Purification of the Angiogenesis Inhibitor 16-kDa Prolactin Fragment from Insect Cells Protein Expression and Purification. Apr, 2003 | Pubmed ID: 12699689 Massenspektrometrische Analyse Glycosphingolipid Antigene Alexandra Bili Yin1, David Hawke2, Dapeng Zhou3,4 1Undergraduate Program, Rice University, 2Proteomics Facility, Department of Pathology, University of Texas MD Anderson Cancer Center, 3Department of Melanoma Medical Oncology, University of Texas MD Anderson Cancer Center, 4University of Texas Graduate School of Biological Sciences at Houston JoVE 4224 Immunologia e infezioni
Massenspektrometrische Analyse Glycosphingolipid Antigene Alexandra Bili Yin1, David Hawke2, Dapeng Zhou3,4 1Undergraduate Program, Rice University, 2Proteomics Facility, Department of Pathology, University of Texas MD Anderson Cancer Center, 3Department of Melanoma Medical Oncology, University of Texas MD Anderson Cancer Center, 4University of Texas Graduate School of Biological Sciences at Houston JoVE 4224 Immunologia e infezioni