Didier Y.R. Stainier Department for Biochemistry and Biophysics University of California San Francisco Biography Publications Institution JoVE Articles Didier Y.R. Stainier has not added a biography. If you are Didier Y.R. Stainier and would like to personalize this page please email our Author Liaison for assistance. Publications Translational Profiling Through Biotinylation of Tagged Ribosomes in Zebrafish Development (Cambridge, England). Oct, 2014 | Pubmed ID: 25231762 Actin Binding GFP Allows 4D In Vivo Imaging of Myofilament Dynamics in the Zebrafish Heart and the Identification of Erbb2 Signaling As a Remodeling Factor of Myofibril Architecture Circulation Research. Oct, 2014 | Pubmed ID: 25228389 Developmental Biology: It Takes Muscle to Make Blood Cells Nature. Aug, 2014 | Pubmed ID: 25119030 Whole Organism High Content Screening Identifies Stimulators of Pancreatic Beta-cell Proliferation PloS One. 2014 | Pubmed ID: 25117518 Intracardiac Flow Dynamics Regulate Atrioventricular Valve Morphogenesis Cardiovascular Research. Oct, 2014 | Pubmed ID: 25100766 Out with the Old, in with the New: Reassessing Morpholino Knockdowns in Light of Genome Editing Technology Development (Cambridge, England). Aug, 2014 | Pubmed ID: 25100652 Minor Class Splicing Shapes the Zebrafish Transcriptome During Development Proceedings of the National Academy of Sciences of the United States of America. Feb, 2014 | Pubmed ID: 24516132 High-resolution Imaging of Cardiomyocyte Behavior Reveals Two Distinct Steps in Ventricular Trabeculation Development (Cambridge, England). Feb, 2014 | Pubmed ID: 24401373 Extensive Conversion of Hepatic Biliary Epithelial Cells to Hepatocytes After Near Total Loss of Hepatocytes in Zebrafish Gastroenterology. Mar, 2014 | Pubmed ID: 24148620 Hepatocyte Growth Factor Signaling in Intrapancreatic Ductal Cells Drives Pancreatic Morphogenesis PLoS Genetics. 2013 | Pubmed ID: 23935514 ETS Factors Regulate Vegf-dependent Arterial Specification Developmental Cell. Jul, 2013 | Pubmed ID: 23830865 Metabolic Regulation of Cellular Plasticity in the Pancreas Current Biology : CB. Jul, 2013 | Pubmed ID: 23791726 In Vivo Cardiac Reprogramming Contributes to Zebrafish Heart Regeneration Nature. Jun, 2013 | Pubmed ID: 23783515 Laminin β1a Controls Distinct Steps During the Establishment of Digestive Organ Laterality Development (Cambridge, England). Jul, 2013 | Pubmed ID: 23757411 Homeostatic Generation of Reactive Oxygen Species Protects the Zebrafish Liver from Steatosis Hepatology (Baltimore, Md.). Oct, 2013 | Pubmed ID: 23744565 The Perivascular Niche Regulates Breast Tumour Dormancy Nature Cell Biology. Jul, 2013 | Pubmed ID: 23728425 Specification of Hepatopancreas Progenitors in Zebrafish by Hnf1ba and Wnt2bb Development (Cambridge, England). Jul, 2013 | Pubmed ID: 23720049 Hepatic Stellate Cells in Liver Development, Regeneration, and Cancer The Journal of Clinical Investigation. May, 2013 | Pubmed ID: 23635788 Autophagy Induction is a Tor- and Tp53-independent Cell Survival Response in a Zebrafish Model of Disrupted Ribosome Biogenesis PLoS Genetics. 2013 | Pubmed ID: 23408911 Ubiad1 is an Antioxidant Enzyme That Regulates ENOS Activity by CoQ10 Synthesis Cell. Jan, 2013 | Pubmed ID: 23374346 Whole-organism Screening for Gluconeogenesis Identifies Activators of Fasting Metabolism Nature Chemical Biology. Feb, 2013 | Pubmed ID: 23201900 MicroRNA-10 Regulates the Angiogenic Behavior of Zebrafish and Human Endothelial Cells by Promoting Vascular Endothelial Growth Factor Signaling Circulation Research. Nov, 2012 | Pubmed ID: 22955733 Nodal Signaling Regulates Endodermal Cell Motility and Actin Dynamics Via Rac1 and Prex1 The Journal of Cell Biology. Sep, 2012 | Pubmed ID: 22945937 Determination of Endothelial Stalk Versus Tip Cell Potential During Angiogenesis by H2.0-like Homeobox-1 Current Biology : CB. Oct, 2012 | Pubmed ID: 22921365 Sox9b is a Key Regulator of Pancreaticobiliary Ductal System Development PLoS Genetics. 2012 | Pubmed ID: 22719264 Adenosine Signaling Promotes Regeneration of Pancreatic β Cells in Vivo Cell Metabolism. Jun, 2012 | Pubmed ID: 22608007 Different Levels of Notch Signaling Regulate Quiescence, Renewal and Differentiation in Pancreatic Endocrine Progenitors Development (Cambridge, England). May, 2012 | Pubmed ID: 22492351 The Basic Helix-loop-helix Transcription Factor, Heart and Neural Crest Derivatives Expressed Transcript 2, Marks Hepatic Stellate Cells in Zebrafish: Analysis of Stellate Cell Entry into the Developing Liver Hepatology (Baltimore, Md.). Nov, 2012 | Pubmed ID: 22488653 Zebrafish in the Study of Early Cardiac Development Circulation Research. Mar, 2012 | Pubmed ID: 22427324 Intrinsic and Extrinsic Modifiers of the Regulative Capacity of the Developing Liver Mechanisms of Development. Jan-Feb, 2012 | Pubmed ID: 22313811 A Monocarboxylate Transporter Required for Hepatocyte Secretion of Ketone Bodies During Fasting Genes & Development. Feb, 2012 | Pubmed ID: 22302940 Mutation of Zebrafish Snapc4 is Associated with Loss of the Intrahepatic Biliary Network Developmental Biology. Mar, 2012 | Pubmed ID: 22222761 Analysis of Sphingosine-1-phosphate Signaling Mutants Reveals Endodermal Requirements for the Growth but Not Dorsoventral Patterning of Jaw Skeletal Precursors Developmental Biology. Feb, 2012 | Pubmed ID: 22185793 Regulation of Intrahepatic Biliary Duct Morphogenesis by Claudin 15-like B Developmental Biology. Jan, 2012 | Pubmed ID: 22020048 Developmental Biology: Physics Adds a Twist to Gut Looping Current Biology : CB. Oct, 2011 | Pubmed ID: 22032191 Molecular Control of Endothelial Cell Behaviour During Blood Vessel Morphogenesis Nature Reviews. Molecular Cell Biology. Sep, 2011 | Pubmed ID: 21860391 Iroquois Homeobox Gene 3 Establishes Fast Conduction in the Cardiac His-Purkinje Network Proceedings of the National Academy of Sciences of the United States of America. Aug, 2011 | Pubmed ID: 21825130 Suppression of Ptf1a Activity Induces Acinar-to-endocrine Conversion Current Biology : CB. Apr, 2011 | Pubmed ID: 21497092 A Slit/miR-218/Robo Regulatory Loop is Required During Heart Tube Formation in Zebrafish Development (Cambridge, England). Apr, 2011 | Pubmed ID: 21385766 Restriction of Hepatic Competence by Fgf Signaling Development (Cambridge, England). Apr, 2011 | Pubmed ID: 21385764 Chromatin Remodelling Complex Dosage Modulates Transcription Factor Function in Heart Development Nature Communications. 2011 | Pubmed ID: 21304516 Uhrf1 and Dnmt1 Are Required for Development and Maintenance of the Zebrafish Lens Developmental Biology. Feb, 2011 | Pubmed ID: 21126517 Dynamic Glucoregulation and Mammalian-like Responses to Metabolic and Developmental Disruption in Zebrafish General and Comparative Endocrinology. Jan, 2011 | Pubmed ID: 20965191 Optogenetic Control of Cardiac Function Science (New York, N.Y.). Nov, 2010 | Pubmed ID: 21071670 A Dual Role for ErbB2 Signaling in Cardiac Trabeculation Development (Cambridge, England). Nov, 2010 | Pubmed ID: 20978078 Cse1l is a Negative Regulator of CFTR-dependent Fluid Secretion Current Biology : CB. Oct, 2010 | Pubmed ID: 20933420 Vertebrate Hedgehog Signaling: Cilia Rule BMC Biology. 2010 | Pubmed ID: 20687907 Cardiac Conduction is Required to Preserve Cardiac Chamber Morphology Proceedings of the National Academy of Sciences of the United States of America. Aug, 2010 | Pubmed ID: 20675583 DeLiver'in Regeneration: Injury Response and Development Seminars in Liver Disease. Aug, 2010 | Pubmed ID: 20665380 Hand2 Regulates Extracellular Matrix Remodeling Essential for Gut-looping Morphogenesis in Zebrafish Developmental Cell. Jun, 2010 | Pubmed ID: 20627079 The Mitochondrial Import Gene Tomm22 is Specifically Required for Hepatocyte Survival and Provides a Liver Regeneration Model Disease Models & Mechanisms. Jul-Aug, 2010 | Pubmed ID: 20483998 Tbx5 and Bmp Signaling Are Essential for Proepicardium Specification in Zebrafish Circulation Research. Jun, 2010 | Pubmed ID: 20413782 Primary Contribution to Zebrafish Heart Regeneration by Gata4(+) Cardiomyocytes Nature. Mar, 2010 | Pubmed ID: 20336144 Haematopoietic Stem Cells Derive Directly from Aortic Endothelium During Development Nature. Mar, 2010 | Pubmed ID: 20154733 Suppression of Alk8-mediated Bmp Signaling Cell-autonomously Induces Pancreatic Beta-cells in Zebrafish Proceedings of the National Academy of Sciences of the United States of America. Jan, 2010 | Pubmed ID: 20080554 Limited Forward Trafficking of Connexin 43 Reduces Cell-cell Coupling in Stressed Human and Mouse Myocardium The Journal of Clinical Investigation. Jan, 2010 | Pubmed ID: 20038810 Noncanonical Activity of Seryl-transfer RNA Synthetase and Vascular Development Trends in Cardiovascular Medicine. Aug, 2009 | Pubmed ID: 20211432 Arterial-venous Segregation by Selective Cell Sprouting: an Alternative Mode of Blood Vessel Formation Science (New York, N.Y.). Oct, 2009 | Pubmed ID: 19815777 Notch Signaling Functions As a Cell-fate Switch Between the Endothelial and Hematopoietic Lineages Current Biology : CB. Oct, 2009 | Pubmed ID: 19747827 Distinct Populations of Quiescent and Proliferative Pancreatic Beta-cells Identified by HOTcre Mediated Labeling Proceedings of the National Academy of Sciences of the United States of America. Sep, 2009 | Pubmed ID: 19706417 Loss of Dnmt1 Catalytic Activity Reveals Multiple Roles for DNA Methylation During Pancreas Development and Regeneration Developmental Biology. Oct, 2009 | Pubmed ID: 19631206 Selective Plane Illumination Microscopy Techniques in Developmental Biology Development (Cambridge, England). Jun, 2009 | Pubmed ID: 19465594 The Extracellular Domain of Smoothened Regulates Ciliary Localization and is Required for High-level Hh Signaling Current Biology : CB. Jun, 2009 | Pubmed ID: 19464178 Transcriptional Silencing and Reactivation in Transgenic Zebrafish Genetics. Jul, 2009 | Pubmed ID: 19433629 Genetic Evidence for a Noncanonical Function of Seryl-tRNA Synthetase in Vascular Development Circulation Research. Jun, 2009 | Pubmed ID: 19423847 Abnormal Nuclear Pore Formation Triggers Apoptosis in the Intestinal Epithelium of Elys-deficient Zebrafish Gastroenterology. Mar, 2009 | Pubmed ID: 19073184 Combinatorial Regulation of Endothelial Gene Expression by Ets and Forkhead Transcription Factors Cell. Dec, 2008 | Pubmed ID: 19070576 The Spinster Homolog, Two of Hearts, is Required for Sphingosine 1-phosphate Signaling in Zebrafish Current Biology : CB. Dec, 2008 | Pubmed ID: 19062281 MicroRNA-138 Modulates Cardiac Patterning During Embryonic Development Proceedings of the National Academy of Sciences of the United States of America. Nov, 2008 | Pubmed ID: 19004786 Bmp2 Signaling Regulates the Hepatic Versus Pancreatic Fate Decision Developmental Cell. Nov, 2008 | Pubmed ID: 19000838 Endothelial Signals Modulate Hepatocyte Apicobasal Polarization in Zebrafish Current Biology : CB. Oct, 2008 | Pubmed ID: 18951027 Regulation of Neurocoel Morphogenesis by Pard6 Gamma B Developmental Biology. Dec, 2008 | Pubmed ID: 18817769 MiR-126 Regulates Angiogenic Signaling and Vascular Integrity Developmental Cell. Aug, 2008 | Pubmed ID: 18694566 Nitroreductase-mediated Cell/tissue Ablation in Zebrafish: a Spatially and Temporally Controlled Ablation Method with Applications in Developmental and Regeneration Studies Nature Protocols. 2008 | Pubmed ID: 18536643 Graded Levels of Ptf1a Differentially Regulate Endocrine and Exocrine Fates in the Developing Pancreas Genes & Development. Jun, 2008 | Pubmed ID: 18519637 Genetic and Physiologic Dissection of the Vertebrate Cardiac Conduction System PLoS Biology. May, 2008 | Pubmed ID: 18479184 Intra-endodermal Interactions Are Required for Pancreatic Beta Cell Induction Developmental Cell. Apr, 2008 | Pubmed ID: 18410733 Multiple Roles for Med12 in Vertebrate Endoderm Development Developmental Biology. May, 2008 | Pubmed ID: 18394596 Foxn4 Directly Regulates Tbx2b Expression and Atrioventricular Canal Formation Genes & Development. Mar, 2008 | Pubmed ID: 18347092 High-speed Imaging of Developing Heart Valves Reveals Interplay of Morphogenesis and Function Development (Cambridge, England). Mar, 2008 | Pubmed ID: 18272595 Lessons from "lower" Organisms: What Worms, Flies, and Zebrafish Can Teach Us About Human Energy Metabolism PLoS Genetics. Nov, 2007 | Pubmed ID: 18081423 Birc2 (cIap1) Regulates Endothelial Cell Integrity and Blood Vessel Homeostasis Nature Genetics. Nov, 2007 | Pubmed ID: 17934460 Even Fluorescence Excitation by Multidirectional Selective Plane Illumination Microscopy (mSPIM) Optics Letters. Sep, 2007 | Pubmed ID: 17767321 Genetic Control of Single Lumen Formation in the Zebrafish Gut Nature Cell Biology. Aug, 2007 | Pubmed ID: 17632505 Zebrafish Model for Human Long QT Syndrome Proceedings of the National Academy of Sciences of the United States of America. Jul, 2007 | Pubmed ID: 17592134 A Transgene-assisted Genetic Screen Identifies Essential Regulators of Vascular Development in Vertebrate Embryos Developmental Biology. Jul, 2007 | Pubmed ID: 17531218 Bmp and Fgf Signaling Are Essential for Liver Specification in Zebrafish Development (Cambridge, England). Jun, 2007 | Pubmed ID: 17507405 The G Protein-coupled Receptor Agtrl1b Regulates Early Development of Myocardial Progenitors Developmental Cell. Mar, 2007 | Pubmed ID: 17336906 Conditional Targeted Cell Ablation in Zebrafish: a New Tool for Regeneration Studies Developmental Dynamics : an Official Publication of the American Association of Anatomists. Apr, 2007 | Pubmed ID: 17326133 A Mutation in Zebrafish Hmgcr1b Reveals a Role for Isoprenoids in Vertebrate Heart-tube Formation Current Biology : CB. Feb, 2007 | Pubmed ID: 17276918 Fgf10 Regulates Hepatopancreatic Ductal System Patterning and Differentiation Nature Genetics. Mar, 2007 | Pubmed ID: 17259985 Microsomal Triglyceride Transfer Protein is Required for Yolk Lipid Utilization and Absorption of Dietary Lipids in Zebrafish Larvae Biochemistry. Dec, 2006 | Pubmed ID: 17176039 The HeArt of Regeneration Cell. Nov, 2006 | Pubmed ID: 17081969 The Yolk Syncytial Layer Regulates Myocardial Migration by Influencing Extracellular Matrix Assembly in Zebrafish Development (Cambridge, England). Oct, 2006 | Pubmed ID: 17008449 A Common Progenitor for Haematopoietic and Endothelial Lineages in the Zebrafish Gastrula Nature. Sep, 2006 | Pubmed ID: 16988712 Mesodermal Wnt2b Signalling Positively Regulates Liver Specification Nature. Aug, 2006 | Pubmed ID: 16799568 In Vivo Cell Biology: Following the Zebrafish Trend Trends in Cell Biology. Feb, 2006 | Pubmed ID: 16406520 Cellular and Molecular Analyses of Vascular Tube and Lumen Formation in Zebrafish Development (Cambridge, England). Dec, 2005 | Pubmed ID: 16251212 Vertebrate Smoothened Functions at the Primary Cilium Nature. Oct, 2005 | Pubmed ID: 16136078 Formation of the Digestive System in Zebrafish: III. Intestinal Epithelium Morphogenesis Developmental Biology. Oct, 2005 | Pubmed ID: 16125164 Genetic and Cellular Analyses of Zebrafish Atrioventricular Cushion and Valve Development Development (Cambridge, England). Sep, 2005 | Pubmed ID: 16107477 Nanor, a Novel Zygotic Gene, is Expressed Initially at the Midblastula Transition in Zebrafish Biochemical and Biophysical Research Communications. Aug, 2005 | Pubmed ID: 15961062 Microarray Analysis of Zebrafish Cloche Mutant Using Amplified CDNA and Identification of Potential Downstream Target Genes Developmental Dynamics : an Official Publication of the American Association of Anatomists. Jul, 2005 | Pubmed ID: 15937927 No Organ Left Behind: Tales of Gut Development and Evolution Science (New York, N.Y.). Mar, 2005 | Pubmed ID: 15790841 Hand2 Regulates Epithelial Formation During Myocardial Diferentiation Current Biology : CB. Mar, 2005 | Pubmed ID: 15786591 Cardiac Development Methods in Cell Biology. 2004 | Pubmed ID: 15602887 Early Myocardial Function Affects Endocardial Cushion Development in Zebrafish PLoS Biology. May, 2004 | Pubmed ID: 15138499 The Endothelial-cell-derived Secreted Factor Egfl7 Regulates Vascular Tube Formation Nature. Apr, 2004 | Pubmed ID: 15085134 Notch Signaling Can Regulate Endoderm Formation in Zebrafish Developmental Dynamics : an Official Publication of the American Association of Anatomists. Apr, 2004 | Pubmed ID: 15042699 Fibronectin Regulates Epithelial Organization During Myocardial Migration in Zebrafish Developmental Cell. Mar, 2004 | Pubmed ID: 15030760 Vegfc is Required for Vascular Development and Endoderm Morphogenesis in Zebrafish EMBO Reports. Jan, 2004 | Pubmed ID: 14710191 A Cellular Framework for Gut-looping Morphogenesis in Zebrafish Science (New York, N.Y.). Oct, 2003 | Pubmed ID: 14576439 Mutation of Weak Atrium/atrial Myosin Heavy Chain Disrupts Atrial Function and Influences Ventricular Morphogenesis in Zebrafish Development (Cambridge, England). Dec, 2003 | Pubmed ID: 14573521 Developmental Biology: Twisting the Body into Shape Nature. Oct, 2003 | Pubmed ID: 14523426 Formation of the Digestive System in Zebrafish. II. Pancreas Morphogenesis Developmental Biology. Sep, 2003 | Pubmed ID: 12941629 The Mix Family Homeodomain Gene Bonnie and Clyde Functions with Other Components of the Nodal Signaling Pathway to Regulate Neural Patterning in Zebrafish Development (Cambridge, England). Oct, 2003 | Pubmed ID: 12930774 Entrails, Heart, Brain, Limbs, and Lymphatics- a Recipe for Success? Developmental Cell. Aug, 2003 | Pubmed ID: 12919671 In Vivo Regulation of the Chicken Cardiac Troponin T Gene Promoter in Zebrafish Embryos Developmental Dynamics : an Official Publication of the American Association of Anatomists. Aug, 2003 | Pubmed ID: 12889057 Formation of the Digestive System in Zebrafish. I. Liver Morphogenesis Developmental Biology. Jan, 2003 | Pubmed ID: 12645931 Two Endothelin 1 Effectors, Hand2 and Bapx1, Pattern Ventral Pharyngeal Cartilage and the Jaw Joint Development (Cambridge, England). Apr, 2003 | Pubmed ID: 12588851 From Endoderm Formation to Liver and Pancreas Development in Zebrafish Mechanisms of Development. Jan, 2003 | Pubmed ID: 12490292 Lipid Receptors in Cardiovascular Development Annual Review of Physiology. 2003 | Pubmed ID: 12471161 Development. Fishing out a New Heart Science (New York, N.Y.). Dec, 2002 | Pubmed ID: 12481123 Pattern Formation: Swimming in Retinoic Acid Current Biology : CB. Oct, 2002 | Pubmed ID: 12401191 The Guts of Endoderm Formation Results and Problems in Cell Differentiation. 2002 | Pubmed ID: 12353482 A Window to the Heart: Can Zebrafish Mutants Help Us Understand Heart Disease in Humans? Trends in Genetics : TIG. Oct, 2002 | Pubmed ID: 12350332 Cardiac Troponin T is Essential in Sarcomere Assembly and Cardiac Contractility Nature Genetics. May, 2002 | Pubmed ID: 11967535 A Glimpse into the Molecular Entrails of Endoderm Formation Genes & Development. Apr, 2002 | Pubmed ID: 11959838 The Elongation Factors Pandora/Spt6 and Foggy/Spt5 Promote Transcription in the Zebrafish Embryo Development (Cambridge, England). Apr, 2002 | Pubmed ID: 11923199 उच्च throughput अनुप्रयोगों के लिए वयस्क zebrafish दिल की वसूली Rima Arnaout1, Sven Reischauer2,3, Didier Y.R. Stainier2,3 1Cardiovascular Research Institute and Division of Cardiology, University of California San Francisco, 2Department for Biochemistry and Biophysics, University of California San Francisco, 3Max-Planck Institute for Heart and Lung Research Biologia
उच्च throughput अनुप्रयोगों के लिए वयस्क zebrafish दिल की वसूली Rima Arnaout1, Sven Reischauer2,3, Didier Y.R. Stainier2,3 1Cardiovascular Research Institute and Division of Cardiology, University of California San Francisco, 2Department for Biochemistry and Biophysics, University of California San Francisco, 3Max-Planck Institute for Heart and Lung Research Biologia