Donald Sakaguchi Department of Genetics, Development and Cell Biology Iowa State University Biography Publications Institution JoVE Articles Donald Sakaguchi has not added a biography. If you are Donald Sakaguchi and would like to personalize this page please email our Author Liaison for assistance. Publications Molecular and Cellular Characterization of a Zebrafish Optic Pathway Tumor Line Implicates Glia-derived Progenitors in Tumorigenesis PloS One. 2014 | Pubmed ID: 25485542 Multipotent Adult Hippocampal Progenitor Cells Maintained As Neurospheres Favor Differentiation Toward Glial Lineages Biotechnology Journal. Jul, 2014 | Pubmed ID: 24844209 Characterization of Structure and Function of the Mouse Retina Using Pattern Electroretinography, Pupil Light Reflex, and Optical Coherence Tomography Veterinary Ophthalmology. Sep, 2012 | Pubmed ID: 22642927 A Mathematical Model for Selective Differentiation of Neural Progenitor Cells on Micropatterned Polymer Substrates Mathematical Biosciences. Aug, 2012 | Pubmed ID: 22569338 Amphiphilic Polyanhydride Films Promote Neural Stem Cell Adhesion and Differentiation Tissue Engineering. Part A. Oct, 2011 | Pubmed ID: 21599544 Transplantation of BDNF-secreting Mesenchymal Stem Cells Provides Neuroprotection in Chronically Hypertensive Rat Eyes Investigative Ophthalmology & Visual Science. Jun, 2011 | Pubmed ID: 21498611 The Influence of Electric Fields on Hippocampal Neural Progenitor Cells Stem Cell Reviews. Dec, 2010 | Pubmed ID: 20665129 Astrocyte-derived Interleukin-6 Promotes Specific Neuronal Differentiation of Neural Progenitor Cells from Adult Hippocampus Journal of Neuroscience Research. Oct, 2010 | Pubmed ID: 20568291 Extracellular Matrix Proteins and Astrocyte-derived Soluble Factors Influence the Differentiation and Proliferation of Adult Neural Progenitor Cells Journal of Biomedical Materials Research. Part A. Sep, 2010 | Pubmed ID: 20336756 In Situ Probing of Cholesterol in Astrocytes at the Single-cell Level Using Laser Desorption Ionization Mass Spectrometric Imaging with Colloidal Silver Rapid Communications in Mass Spectrometry : RCM. Apr, 2010 | Pubmed ID: 20301106 Exogenous Modulation of Intrinsic Optic Nerve Neuroprotective Activity Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie. Aug, 2010 | Pubmed ID: 20229104 Differentiation and Behavior of Human Neural Progenitors on Micropatterned Substrates and in the Developing Retina Journal of Neuroscience Research. May, 2010 | Pubmed ID: 20029967 Integrins Contribute to Initial Morphological Development and Process Outgrowth in Rat Adult Hippocampal Progenitor Cells Journal of Molecular Neuroscience : MN. Mar, 2010 | Pubmed ID: 19499350 Brain-derived Neurotrophic Factor Released from Engineered Mesenchymal Stem Cells Attenuates Glutamate- and Hydrogen Peroxide-mediated Death of Staurosporine-differentiated RGC-5 Cells Experimental Eye Research. Oct, 2009 | Pubmed ID: 19524566 Soluble Factors from Neocortical Astrocytes Enhance Neuronal Differentiation of Neural Progenitor Cells from Adult Rat Hippocampus on Micropatterned Polymer Substrates Journal of Biomedical Materials Research. Part A. Nov, 2009 | Pubmed ID: 18985780 Patterns of Distribution of Oxygen-binding Globins, Neuroglobin and Cytoglobin in Human Retina Archives of Ophthalmology. Nov, 2008 | Pubmed ID: 19001220 Neuroglobin and Cytoglobin Distribution in the Anterior Eye Segment: a Comparative Immunohistochemical Study The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. Sep, 2008 | Pubmed ID: 18574250 Proteomic Differentiation Between Murine Retinal and Brain-derived Progenitor Cells Stem Cells and Development. Feb, 2008 | Pubmed ID: 18225980 Cell Birth and Death in the Developing Retina of the Brazilian Opossum, Monodelphis Domestica Brain Research. Feb, 2008 | Pubmed ID: 18191114 Recovery of Canine Retina and Optic Nerve Function After Acute Elevation of Intraocular Pressure: Implications for Canine Glaucoma Treatment Veterinary Ophthalmology. Nov-Dec, 2007 | Pubmed ID: 17973841 Evaluation of Retinal Status Using Chromatic Pupil Light Reflex Activity in Healthy and Diseased Canine Eyes Investigative Ophthalmology & Visual Science. Nov, 2007 | Pubmed ID: 17962471 Amyloid-beta Peptide Affects Viability but Not Differentiation of Embryonic and Adult Rat Hippocampal Progenitor Cells Experimental Neurology. Feb, 2007 | Pubmed ID: 17112517 Retinal Synthesis and Deposition of Complement Components Induced by Ocular Hypertension Experimental Eye Research. Sep, 2006 | Pubmed ID: 16677633 Directed Growth and Selective Differentiation of Neural Progenitor Cells on Micropatterned Polymer Substrates Biomaterials. Aug, 2006 | Pubmed ID: 16616776 Neuroglobin and Cytoglobin: Oxygen-binding Proteins in Retinal Neurons Investigative Ophthalmology & Visual Science. Mar, 2006 | Pubmed ID: 16505036 Morphological Integration and Functional Assessment of Transplanted Neural Progenitor Cells in Healthy and Acute Ischemic Rat Eyes Experimental Eye Research. Apr, 2006 | Pubmed ID: 16213484 Inhibition of Integrin-mediated Adhesion and Signaling Disrupts Retinal Development Developmental Biology. Nov, 2004 | Pubmed ID: 15464583 Functional Evaluation of Retina and Optic Nerve in the Rat Model of Chronic Ocular Hypertension Experimental Eye Research. Jul, 2004 | Pubmed ID: 15183102 Stem Cells and Retinal Repair Progress in Retinal and Eye Research. Mar, 2004 | Pubmed ID: 15094129 Inhibition of Protein Tyrosine Kinase Activity Disrupts Early Retinal Development Developmental Biology. Feb, 2004 | Pubmed ID: 14729490 Laser-induced Mouse Model of Chronic Ocular Hypertension Investigative Ophthalmology & Visual Science. Oct, 2003 | Pubmed ID: 14507878 Characterization of the Pupil Light Reflex, Electroretinogram and Tonometric Parameters in Healthy Mouse Eyes Current Eye Research. Jun, 2003 | Pubmed ID: 12868018 Temporary Elevation of the Intraocular Pressure by Cauterization of Vortex and Episcleral Veins in Rats Causes Functional Deficits in the Retina and Optic Nerve Experimental Eye Research. Jul, 2003 | Pubmed ID: 12823985 Functional Characterization of Retina and Optic Nerve After Acute Ocular Ischemia in Rats Investigative Ophthalmology & Visual Science. Jun, 2003 | Pubmed ID: 12766062 Incorporation of Murine Brain Progenitor Cells into the Developing Mammalian Retina Investigative Ophthalmology & Visual Science. Jan, 2003 | Pubmed ID: 12506105 Characterization of the Pupil Light Reflex, Electroretinogram and Tonometric Parameters in Healthy Rat Eyes Current Eye Research. Aug, 2002 | Pubmed ID: 12525960 Expression Patterns of Focal Adhesion Associated Proteins in the Developing Retina Developmental Dynamics : an Official Publication of the American Association of Anatomists. Dec, 2002 | Pubmed ID: 12454930 Expression of SNAP-25 During Mammalian Retinal Development: Thinking Outside the Synapse Seminars in Cell & Developmental Biology. Apr, 2002 | Pubmed ID: 12127142 High Throughput Characterization of Adult Stem Cells Engineered for Delivery of Therapeutic Factors for Neuroprotective Strategies Anup D. Sharma1, Pavel A. Brodskiy1,3, Emma M. Petersen2,3, Melih Dagdeviren2, Eun-Ah Ye2, Surya K. Mallapragada1, Donald Sakaguchi2,3 1Department of Chemical and Biological Engineering, Iowa State University, 2Department of Genetics, Development and Cell Biology, Iowa State University, 3Biology Program, Iowa State University JoVE 52242 Medicina
High Throughput Characterization of Adult Stem Cells Engineered for Delivery of Therapeutic Factors for Neuroprotective Strategies Anup D. Sharma1, Pavel A. Brodskiy1,3, Emma M. Petersen2,3, Melih Dagdeviren2, Eun-Ah Ye2, Surya K. Mallapragada1, Donald Sakaguchi2,3 1Department of Chemical and Biological Engineering, Iowa State University, 2Department of Genetics, Development and Cell Biology, Iowa State University, 3Biology Program, Iowa State University JoVE 52242 Medicina