Dorien Ward-van Oostwaard Department of Anatomy and Embryology Leiden University Medical Center Biography Publications Institution JoVE Articles Dorien Ward-van Oostwaard has not added a biography. If you are Dorien Ward-van Oostwaard and would like to personalize this page please email our Author Liaison for assistance. Publications Subtype-specific Promoter-driven Action Potential Imaging for Precise Disease Modelling and Drug Testing in HiPSC-derived Cardiomyocytes European Heart Journal. Jan, 2017 | Pubmed ID: 28182242 A New HERG Allosteric Modulator Rescues Genetic and Drug-induced Long-QT Syndrome Phenotypes in Cardiomyocytes from Isogenic Pairs of Patient Induced Pluripotent Stem Cells EMBO Molecular Medicine. 09, 2016 | Pubmed ID: 27470144 Subtype-specific Promoter-driven Action Potential Imaging for Precise Disease Modelling and Drug Testing in HiPSC-derived Cardiomyocytes European Heart Journal. Jun, 2016 | Pubmed ID: 27311732 Altered Calcium Handling and Increased Contraction Force in Human Embryonic Stem Cell Derived Cardiomyocytes Following Short Term Dexamethasone Exposure Biochemical and Biophysical Research Communications. Nov, 2015 | Pubmed ID: 26456652 Recessive Cardiac Phenotypes in Induced Pluripotent Stem Cell Models of Jervell and Lange-Nielsen Syndrome: Disease Mechanisms and Pharmacological Rescue Proceedings of the National Academy of Sciences of the United States of America. Dec, 2014 | Pubmed ID: 25453094 BMP4 Promotes EMT and Mesodermal Commitment in Human Embryonic Stem Cells Via SLUG and MSX2 Stem Cells (Dayton, Ohio). Mar, 2014 | Pubmed ID: 24549638 Isogenic Human Pluripotent Stem Cell Pairs Reveal the Role of a KCNH2 Mutation in Long-QT Syndrome The EMBO Journal. Dec, 2013 | Pubmed ID: 24213244 Cardiomyocytes Derived from Pluripotent Stem Cells Recapitulate Electrophysiological Characteristics of an Overlap Syndrome of Cardiac Sodium Channel Disease Circulation. Jun, 2012 | Pubmed ID: 22647976 Screening Ethnically Diverse Human Embryonic Stem Cells Identifies a Chromosome 20 Minimal Amplicon Conferring Growth Advantage Nature Biotechnology. Dec, 2011 | Pubmed ID: 22119741 NKX2-5(eGFP/w) HESCs for Isolation of Human Cardiac Progenitors and Cardiomyocytes Nature Methods. Dec, 2011 | Pubmed ID: 22020065 Inhibition of ROCK Improves Survival of Human Embryonic Stem Cell-derived Cardiomyocytes After Dissociation Annals of the New York Academy of Sciences. Feb, 2010 | Pubmed ID: 20201886 Identification of Cell Surface Proteins for Antibody-based Selection of Human Embryonic Stem Cell-derived Cardiomyocytes Journal of Proteome Research. Mar, 2010 | Pubmed ID: 20088484 Improvement of Mouse Cardiac Function by HESC-derived Cardiomyocytes Correlates with Vascularity but Not Graft Size Stem Cell Research. Sep-Nov, 2009 | Pubmed ID: 19560991 Feeder-free Monolayer Cultures of Human Embryonic Stem Cells Express an Epithelial Plasma Membrane Protein Profile Stem Cells (Dayton, Ohio). Nov, 2008 | Pubmed ID: 18703662 Recombinant Vitronectin is a Functionally Defined Substrate That Supports Human Embryonic Stem Cell Self-renewal Via Alphavbeta5 Integrin Stem Cells (Dayton, Ohio). Sep, 2008 | Pubmed ID: 18599809 Insulin Redirects Differentiation from Cardiogenic Mesoderm and Endoderm to Neuroectoderm in Differentiating Human Embryonic Stem Cells Stem Cells (Dayton, Ohio). Mar, 2008 | Pubmed ID: 18096723 Human Embryonic Stem Cell-derived Cardiomyocytes Survive and Mature in the Mouse Heart and Transiently Improve Function After Myocardial Infarction Stem Cell Research. Oct, 2007 | Pubmed ID: 19383383 Gene-specific Vulnerability to Imprinting Variability in Human Embryonic Stem Cell Lines Genome Research. Dec, 2007 | Pubmed ID: 17989250 Monitoring of Cell Therapy and Assessment of Cardiac Function Using Magnetic Resonance Imaging in a Mouse Model of Myocardial Infarction Nature Protocols. 2007 | Pubmed ID: 17947998 An Experimental Correction for Arginine-to-proline Conversion Artifacts in SILAC-based Quantitative Proteomics Nature Methods. Sep, 2007 | Pubmed ID: 17762871 Restriction Landmark Genome Scanning Identifies Culture-induced DNA Methylation Instability in the Human Embryonic Stem Cell Epigenome Human Molecular Genetics. May, 2007 | Pubmed ID: 17409196 Genome-wide Transcriptional Profiling of Human Embryonic Stem Cells Differentiating to Cardiomyocytes Stem Cells (Dayton, Ohio). Aug, 2006 | Pubmed ID: 16675594 A Quest for Human and Mouse Embryonic Stem Cell-specific Proteins Molecular & Cellular Proteomics : MCP. Jul, 2006 | Pubmed ID: 16600995 Human Embryonic Stem Cells: Towards Therapies for Cardiac Disease. Derivation of a Dutch Human Embryonic Stem Cell Line Reproductive Biomedicine Online. Oct, 2005 | Pubmed ID: 16274613 Increased Cardiomyocyte Differentiation from Human Embryonic Stem Cells in Serum-free Cultures Stem Cells (Dayton, Ohio). Jun-Jul, 2005 | Pubmed ID: 15917473 Regulation of Human Embryonic Stem Cell Differentiation by BMP-2 and Its Antagonist Noggin Journal of Cell Science. Mar, 2004 | Pubmed ID: 14996946 Differentiation of Human Embryonic Stem Cells to Cardiomyocytes: Role of Coculture with Visceral Endoderm-like Cells Circulation. Jun, 2003 | Pubmed ID: 12742992 Çok Elektrodlu Diziler (ÇÇA'lar) Kullanan İnsan Pluripotent Kök Hücresinden Türetilmiş Kardiyomiyositlerin (hPSC-CM'ler) Elektrofizyolojik Analizi Luca Sala1, Dorien Ward-van Oostwaard1, Leon G. J. Tertoolen1, Christine L Mummery1,2, Milena Bellin1 1Department of Anatomy and Embryology, Leiden University Medical Center, 2Department of Applied Stem Cell Technologies, University of Twente JoVE 55587 Biologia dello sviluppo
Çok Elektrodlu Diziler (ÇÇA'lar) Kullanan İnsan Pluripotent Kök Hücresinden Türetilmiş Kardiyomiyositlerin (hPSC-CM'ler) Elektrofizyolojik Analizi Luca Sala1, Dorien Ward-van Oostwaard1, Leon G. J. Tertoolen1, Christine L Mummery1,2, Milena Bellin1 1Department of Anatomy and Embryology, Leiden University Medical Center, 2Department of Applied Stem Cell Technologies, University of Twente JoVE 55587 Biologia dello sviluppo