Eiji Shigetomi Department of Neuropharmacology, Faculty of Medicine University of Yamanashi Biography Publications Institution JoVE Articles Eiji Shigetomi has not added a biography. If you are Eiji Shigetomi and would like to personalize this page please email our Author Liaison for assistance. Publications Transient Astrocytic MGluR5 Expression Drives Synaptic Plasticity and Subsequent Chronic Pain in Mice The Journal of Experimental Medicine. 04, 2022 | Pubmed ID: 35319723 Effects of Fatty Acid Metabolites on Nocturia Scientific Reports. 02, 2022 | Pubmed ID: 35197540 Abnormal Ca Signals in Reactive Astrocytes As a Common Cause of Brain Diseases International Journal of Molecular Sciences. Dec, 2021 | Pubmed ID: 35008573 Adenosine A Receptor Down-regulates Metabotropic Glutamate Receptor 5 in Astrocytes During Postnatal Development Glia. 11, 2021 | Pubmed ID: 34339538 Transnasal Transplantation of Human Induced Pluripotent Stem Cell-derived Microglia to the Brain of Immunocompetent Mice Glia. 10, 2021 | Pubmed ID: 34309082 Different Effects of GsMTx4 on Nocturia Associated with the Circadian Clock and Piezo1 Expression in Mice Life Sciences. Aug, 2021 | Pubmed ID: 33930366 Reactive Astrocyte-driven Epileptogenesis is Induced by Microglia Initially Activated Following Status Epilepticus JCI Insight. 05, 2021 | Pubmed ID: 33830944 Author Correction: Intermittent Restraint Stress Induces Circadian Misalignment in the Mouse Bladder, Leading to Nocturia Scientific Reports. Nov, 2019 | Pubmed ID: 31700120 Intermittent Restraint Stress Induces Circadian Misalignment in the Mouse Bladder, Leading to Nocturia Scientific Reports. 07, 2019 | Pubmed ID: 31296902 Aberrant Calcium Signals in Reactive Astrocytes: A Key Process in Neurological Disorders International Journal of Molecular Sciences. Feb, 2019 | Pubmed ID: 30823575 The Time-dependent Variation of ATP Release in Mouse Primary-cultured Urothelial Cells is Regulated by the Clock Gene Neurourology and Urodynamics. 11, 2018 | Pubmed ID: 30106187 Anti-Depressant Fluoxetine Reveals Its Therapeutic Effect Via Astrocytes EBioMedicine. Jun, 2018 | Pubmed ID: 29887330 The Oscillation of Intracellular Ca Influx Associated with the Circadian Expression of Piezo1 and TRPV4 in the Bladder Urothelium Scientific Reports. 04, 2018 | Pubmed ID: 29632308 Aberrant Astrocyte Ca Signals "AxCa Signals" Exacerbate Pathological Alterations in an Alexander Disease Model Glia. 05, 2018 | Pubmed ID: 29383757 Role of Purinergic Receptor P2Y1 in Spatiotemporal Ca Dynamics in Astrocytes The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. 02, 2018 | Pubmed ID: 29305530 The Circadian Expression of Piezo1, TRPV4, Connexin26, and VNUT, Associated with the Expression Levels of the Clock Genes in Mouse Primary Cultured Urothelial Cells Neurourology and Urodynamics. 03, 2018 | Pubmed ID: 28881406 Author Correction: Reactive Astrocytes Function As Phagocytes After Brain Ischemia Via ABCA1-mediated Pathway Nature Communications. 11, 2017 | Pubmed ID: 29138397 Neural Circuit-Specialized Astrocytes: Transcriptomic, Proteomic, Morphological, and Functional Evidence Neuron. Aug, 2017 | Pubmed ID: 28712653 Reactive Astrocytes Function As Phagocytes After Brain Ischemia Via ABCA1-mediated Pathway Nature Communications. 06, 2017 | Pubmed ID: 28642575 Transformation of Astrocytes to a Neuroprotective Phenotype by Microglia Via P2Y Receptor Downregulation Cell Reports. 05, 2017 | Pubmed ID: 28494865 P2Y-deficiency Increases Micturition Frequency and Attenuates Sustained Contractility of the Urinary Bladder in Mice Scientific Reports. 04, 2017 | Pubmed ID: 28396595 Clock Genes Regulate the Circadian Expression of Piezo1, TRPV4, Connexin26, and VNUT in an Ex Vivo Mouse Bladder Mucosa PloS One. 2017 | Pubmed ID: 28060940 The Clock Mutant Mouse is a Novel Experimental Model for Nocturia and Nocturnal Polyuria Neurourology and Urodynamics. Apr, 2017 | Pubmed ID: 27348079 Urothelial ATP Exocytosis: Regulation of Bladder Compliance in the Urine Storage Phase Scientific Reports. 07, 2016 | Pubmed ID: 27412485 Cortical Astrocytes Rewire Somatosensory Cortical Circuits for Peripheral Neuropathic Pain The Journal of Clinical Investigation. May, 2016 | Pubmed ID: 27064281 Probing the Complexities of Astrocyte Calcium Signaling Trends in Cell Biology. Apr, 2016 | Pubmed ID: 26896246 Müller Cell-mediated Neurite Outgrowth of the Retinal Ganglion Cells Via P2Y Receptor Signals Journal of Neurochemistry. Feb, 2016 | Pubmed ID: 26560804 Imaging Calcium Microdomains Within Entire Astrocyte Territories and Endfeet with GCaMPs Expressed Using Adeno-associated Viruses The Journal of General Physiology. May, 2013 | Pubmed ID: 23589582 TRPA1 Channels Regulate Astrocyte Resting Calcium and Inhibitory Synapse Efficacy Through GAT-3 Nature Neuroscience. Jan, 2012 | Pubmed ID: 22158513 Neuronal P2X2 Receptors Are Mobile ATP Sensors That Explore the Plasma Membrane when Activated The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2011 | Pubmed ID: 22090499 [Synaptic Regulation by Astrocytes] Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica. Oct, 2011 | Pubmed ID: 21986065 Bulk Loading of Calcium Indicator Dyes to Study Astrocyte Physiology: Key Limitations and Improvements Using Morphological Maps The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2011 | Pubmed ID: 21697385 Monitoring Astrocyte Calcium Microdomains with Improved Membrane Targeted GCaMP Reporters Neuron Glia Biology. Dec, 2010 | Pubmed ID: 21205365 A Genetically Targeted Optical Sensor to Monitor Calcium Signals in Astrocyte Processes Nature Neuroscience. Jun, 2010 | Pubmed ID: 20495558 Two Forms of Astrocyte Calcium Excitability Have Distinct Effects on NMDA Receptor-mediated Slow Inward Currents in Pyramidal Neurons The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2008 | Pubmed ID: 18579739 Tracking Transmitter-gated P2X Cation Channel Activation in Vitro and in Vivo Nature Methods. Jan, 2008 | Pubmed ID: 18084300 [Purinergic Regulatory Complex in the Brain Synapses] Nihon Shinkei Seishin Yakurigaku Zasshi = Japanese Journal of Psychopharmacology. Jun, 2007 | Pubmed ID: 17633523 Facilitation of Spontaneous Glycine Release by Anoxia Potentiates NMDA Receptor Current in the Hypoglossal Motor Neurons of the Rat The European Journal of Neuroscience. Mar, 2007 | Pubmed ID: 17408431 Blocker-resistant Presynaptic Voltage-dependent Ca2+ Channels Underlying Glutamate Release in Mice Nucleus Tractus Solitarii Brain Research. Aug, 2006 | Pubmed ID: 16814754 A Dual-role Played by Extracellular ATP in Frequency-filtering of the Nucleus Tractus Solitarii Network Advances in Experimental Medicine and Biology. 2004 | Pubmed ID: 15602957 Action Potential-independent Release of Glutamate by Ca2+ Entry Through Presynaptic P2X Receptors Elicits Postsynaptic Firing in the Brainstem Autonomic Network The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2004 | Pubmed ID: 15044552 ATP- and Adenosine-mediated Signaling in the Central Nervous System: Synaptic Purinoceptors: the Stage for ATP to Play Its "dual-role" Journal of Pharmacological Sciences. Feb, 2004 | Pubmed ID: 14978346 Differential Increases in P2X Receptor Levels in Rat Vagal Efferent Neurones Following a Vagal Nerve Section Brain Research. Jul, 2003 | Pubmed ID: 12788520 Analysis of the Molecular Mechanisms Controlling Synaptic Transmission by Patch-clamp Recording in Brainstem Slices Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica. Apr, 2003 | Pubmed ID: 12777844 In vivo Wide-Field en Two-Photon Calcium Imaging van een muis met behulp van een groot craniaal venster Satoshi Manita1, Eiji Shigetomi2,3, Haruhiko Bito4, Schuichi Koizumi2,3, Kazuo Kitamura1 1Department of Neurophysiology, Faculty of Medicine, University of Yamanashi, 2Department of Neuropharmacology, Faculty of Medicine, University of Yamanashi, 3Yamanashi GLIA center, Interdisciplinary Graduate School of Medicine, University of Yamanashi, 4Department of Neurochemistry, Graduate School of Medicine, The University of Tokyo JoVE 64224 Neuroscienze Transplantatie van door de mens geïnduceerde pluripotente stamcel-afgeleide microglia in immunocompetente muizenhersenen via niet-invasieve transnasale route Bijay Parajuli1,2, Youichi Shinozaki1,2, Eiji Shigetomi1,2, Schuichi Koizumi1,2 1Department of Neuropharmacology, Interdisciplinary Graduate School of Medicine, University of Yamanashi, 2GLIA Center, University of Yamanashi JoVE 63574 Neuroscienze Het meten van de buurt plasmamembraan en Global intracellulair calcium Dynamics in Astrocyten Eiji Shigetomi1, Baljit S. Khakh1 1Departments of Physiology and Neurobiology, David Geffen School of Medicine, University of California, Los Angeles JoVE 1142 Biologia
In vivo Wide-Field en Two-Photon Calcium Imaging van een muis met behulp van een groot craniaal venster Satoshi Manita1, Eiji Shigetomi2,3, Haruhiko Bito4, Schuichi Koizumi2,3, Kazuo Kitamura1 1Department of Neurophysiology, Faculty of Medicine, University of Yamanashi, 2Department of Neuropharmacology, Faculty of Medicine, University of Yamanashi, 3Yamanashi GLIA center, Interdisciplinary Graduate School of Medicine, University of Yamanashi, 4Department of Neurochemistry, Graduate School of Medicine, The University of Tokyo JoVE 64224 Neuroscienze
Transplantatie van door de mens geïnduceerde pluripotente stamcel-afgeleide microglia in immunocompetente muizenhersenen via niet-invasieve transnasale route Bijay Parajuli1,2, Youichi Shinozaki1,2, Eiji Shigetomi1,2, Schuichi Koizumi1,2 1Department of Neuropharmacology, Interdisciplinary Graduate School of Medicine, University of Yamanashi, 2GLIA Center, University of Yamanashi JoVE 63574 Neuroscienze
Het meten van de buurt plasmamembraan en Global intracellulair calcium Dynamics in Astrocyten Eiji Shigetomi1, Baljit S. Khakh1 1Departments of Physiology and Neurobiology, David Geffen School of Medicine, University of California, Los Angeles JoVE 1142 Biologia