Elva Diaz Pharmacology UC Davis School of Medicine Biography Publications Institution JoVE Articles Elva DiazProfessor I have a broad background in biochemistry, molecular and cell biology and genomics in studies of the mammalian nervous system. I was born and raised in San Jose, CA to parents originally from Mexico. My interest in science and math in high school eventually led me to a career in biomedical research. I earned a bachelor’s degree from Harvard University in Biochemical Sciences in 1993. Following a summer internship at Merck & Co at Rahway, NJ, I pursued graduate studies with Suzanne Pfeffer at Stanford University and earned a Ph.D. in Biochemistry in 1999. My graduate studies involved the molecular mechanisms of receptor trafficking in non-neuronal cells. As a postdoctoral scholar I switched fields into developmental neurobiology and worked with Tito Serafini and John Ngai at UC Berkeley and with Marc Tessier-Lavigne at UCSF. In 2003 I became an Assistant Professor in the Department of Pharmacology at UC Davis School of Medicine and in 2010 I was promoted to Associate Professor with tenure. I was promoted to Full Professor in 2018.My main research interest is to understand molecular mechanisms of brain development, function and disease. My lab employs functional genomics approaches to identify genes upregulated during distinct phases of brain development. In particular, we focus on two main areas: neural proliferation and synapse development and we have identified several candidate genes involved in these processes. We utilize a combination of approaches including imaging, primary neuronal culture, biochemistry and electrophysiology. Publications SynDIG1 Regulation of Excitatory Synapse Maturation The Journal of Physiology. Jan, 2012 | Pubmed ID: 21878521 Histone Deacetylase Activity is Necessary for Left-right Patterning During Vertebrate Development BMC Developmental Biology. Month, 2011 | Pubmed ID: 21599922 Mechanisms of Excitatory Synapse Maturation by Trans-synaptic Organizing Complexes Current Opinion in Neurobiology. Apr, 2011 | Pubmed ID: 21242087 Regulation of AMPA Receptors by Transmembrane Accessory Proteins The European Journal of Neuroscience. Jul, 2010 | Pubmed ID: 20946114 SynDIG1 Regulation of Synaptic AMPA Receptor Targeting Communicative & Integrative Biology. Jul, 2010 | Pubmed ID: 20798822 SynDIG1: an Activity-regulated, AMPA- Receptor-interacting Transmembrane Protein That Regulates Excitatory Synapse Development Neuron. Jan, 2010 | Pubmed ID: 20152115 One Decade Later: What Has Gene Expression Profiling Told Us About Neuronal Cell Types, Brain Function and Disease? Current Genomics. Aug, 2009 | Pubmed ID: 20119529 From Microarrays to Mechanisms of Brain Development and Function Biochemical and Biophysical Research Communications. Jul, 2009 | Pubmed ID: 19460360 From Cerebellar Proliferation to Tumorigenesis: New Insights into the Role of Mad3 Cell Cycle (Georgetown, Tex.). Feb, 2008 | Pubmed ID: 18235219 A Novel Role of the Mad Family Member Mad3 in Cerebellar Granule Neuron Precursor Proliferation Molecular and Cellular Biology. Dec, 2007 | Pubmed ID: 17893326 A Functional Genomics Guide to the Galaxy of Neuronal Cell Types Nature Neuroscience. Jan, 2006 | Pubmed ID: 16378087 Analysis of Gene Expression in the Developing Mouse Retina Proceedings of the National Academy of Sciences of the United States of America. Apr, 2003 | Pubmed ID: 12702772 Molecular Analysis of Gene Expression in the Developing Pontocerebellar Projection System Neuron. Oct, 2002 | Pubmed ID: 12408845 Beyin Zarı Proteinlerinin Palmitoylarasyonunun Kantitatif Tayini için Acyl-PEGyl Exchange Jel Shift Tayini David J. Speca1, Elva Diaz1 1Department of Pharmacology, UC Davis School of Medicine JoVE 61018 Biochimica Formation Odak: bir hücreye dayalı tahlil, bir genin onkojenik potansiyeli belirlemek için Angel Alvarez1, Gustavo A. Barisone1, Elva Diaz1 1Department of Pharmacology, University of California, Davis JoVE 51742 Medicina DNA Mikroarray'ler: Örnek Kalite Kontrol, Dizi Hibridizasyon ve Tarama Elva Diaz1, Gustavo A. Barisone1 1Department of Pharmacology, University of California, Davis JoVE 2546 Biologia
Beyin Zarı Proteinlerinin Palmitoylarasyonunun Kantitatif Tayini için Acyl-PEGyl Exchange Jel Shift Tayini David J. Speca1, Elva Diaz1 1Department of Pharmacology, UC Davis School of Medicine JoVE 61018 Biochimica
Formation Odak: bir hücreye dayalı tahlil, bir genin onkojenik potansiyeli belirlemek için Angel Alvarez1, Gustavo A. Barisone1, Elva Diaz1 1Department of Pharmacology, University of California, Davis JoVE 51742 Medicina
DNA Mikroarray'ler: Örnek Kalite Kontrol, Dizi Hibridizasyon ve Tarama Elva Diaz1, Gustavo A. Barisone1 1Department of Pharmacology, University of California, Davis JoVE 2546 Biologia