Evan Y. Snyder Department of Pediatrics University of California, San Diego School of Medicine Biography Publications Institution JoVE Articles Evan Y. Snyder has not added a biography. If you are Evan Y. Snyder and would like to personalize this page please email our Author Liaison for assistance. Publications Induced Pluripotency and Spontaneous Reversal of Cellular Aging in Supercentenarian Donor Cells Biochemical and Biophysical Research Communications. 05, 2020 | Pubmed ID: 32115145 Modeling Complex Neurological Diseases with Stem Cells: A Study of Bipolar Disorder Results and Problems in Cell Differentiation. 2018 | Pubmed ID: 30209664 Quantitative Analysis of Human Pluripotency and Neural Specification by In-Depth (Phospho)Proteomic Profiling Stem Cell Reports. 09, 2016 | Pubmed ID: 27569059 Phosphoproteomic Analysis: An Emerging Role in Deciphering Cellular Signaling in Human Embryonic Stem Cells and Their Differentiated Derivatives Stem Cell Reviews. Oct, 2011 | Pubmed ID: 22009073 Modeling Complex Neuropsychiatric Disorders with Human Induced Pluripotent Stem Cells Current Opinion in Pharmacology. Oct, 2011 | Pubmed ID: 21723195 DMSO-Free Programmed Cryopreservation of Fully Dissociated and Adherent Human Induced Pluripotent Stem Cells Stem Cells International. 2011 | Pubmed ID: 21716669 The Intricate Dance Between Repair and Inflammation: Introduction to Special Issue Experimental Neurology. Jul, 2011 | Pubmed ID: 21596040 Overexpression of Basic Helix-Loop-Helix Transcription Factors Enhances Neuronal Differentiation of Fetal Human Neural Progenitor Cells in Various Ways Stem Cells and Development. Jul, 2011 | Pubmed ID: 21561385 The Risk of Putting Something Where It Does Not Belong: Mesenchymal Stem Cells Produce Masses in the Brain Experimental Neurology. Jul, 2011 | Pubmed ID: 21420402 Long-term Magnetic Resonance Imaging of Stem Cells in Neonatal Ischemic Injury Annals of Neurology. Feb, 2011 | Pubmed ID: 21387373 Dorsomorphin Promotes Human Embryonic Stem Cell Self-renewal Angewandte Chemie (International Ed. in English). Apr, 2011 | Pubmed ID: 21384475 Self-renewal Induced Efficiently, Safely, and Effective Therapeutically with One Regulatable Gene in a Human Somatic Progenitor Cell Proceedings of the National Academy of Sciences of the United States of America. Mar, 2011 | Pubmed ID: 21378266 Neurotransplantation of Stem Cells Genetically Modified to Express Human Dopamine Transporter Reduces Alcohol Consumption Stem Cell Research & Therapy. 2010 | Pubmed ID: 21122109 Early Acquisition of Neural Crest Competence During HESCs Neuralization PloS One. 2010 | Pubmed ID: 21085480 Nna1 Mediates Purkinje Cell Dendritic Development Via Lysyl Oxidase Propeptide and NF-κB Signaling Neuron. Oct, 2010 | Pubmed ID: 20920790 Culture and Manipulation of Neural Stem Cells Advances in Experimental Medicine and Biology. 2010 | Pubmed ID: 20455492 Microarray-based Transcriptional and Epigenetic Profiling of Matrix Metalloproteinases, Collagens, and Related Genes in Cancer The Journal of Biological Chemistry. Jun, 2010 | Pubmed ID: 20404328 Derivation of Vasculature from Embryonic Stem Cells Current Protocols in Stem Cell Biology. Mar, 2010 | Pubmed ID: 20200855 Communication Via Gap Junctions Underlies Early Functional and Beneficial Interactions Between Grafted Neural Stem Cells and the Host Proceedings of the National Academy of Sciences of the United States of America. Mar, 2010 | Pubmed ID: 20147621 Screening the Mammalian Extracellular Proteome for Regulators of Embryonic Human Stem Cell Pluripotency Proceedings of the National Academy of Sciences of the United States of America. Feb, 2010 | Pubmed ID: 20133595 The Transcriptional Network for Mesenchymal Transformation of Brain Tumours Nature. Jan, 2010 | Pubmed ID: 20032975 Important Precautions when Deriving Patient-specific Neural Elements from Pluripotent Cells Cytotherapy. 2009 | Pubmed ID: 19903095 Cross-talk Between Stem Cells and the Dysfunctional Brain is Facilitated by Manipulating the Niche: Evidence from an Adhesion Molecule Stem Cells (Dayton, Ohio). Nov, 2009 | Pubmed ID: 19785036 A Safer Stem Cell: on Guard Against Cancer Nature Medicine. Sep, 2009 | Pubmed ID: 19734873 Culture System for Rodent and Human Oligodendrocyte Specification, Lineage Progression, and Maturation Current Protocols in Stem Cell Biology. Sep, 2009 | Pubmed ID: 19725014 Phosphoproteomic Analysis of Human Embryonic Stem Cells Cell Stem Cell. Aug, 2009 | Pubmed ID: 19664994 Neural Stem Cell Transplantation Benefits a Monogenic Neurometabolic Disorder During the Symptomatic Phase of Disease Stem Cells (Dayton, Ohio). Sep, 2009 | Pubmed ID: 19591217 Maintaining and Engineering Neural Stem Cells for Delivery of Genetically Encoded Therapy to Brain Tumors Methods in Molecular Biology (Clifton, N.J.). 2009 | Pubmed ID: 19582432 Long-term Multilayer Adherent Network (MAN) Expansion, Maintenance, and Characterization, Chemical and Genetic Manipulation, and Transplantation of Human Fetal Forebrain Neural Stem Cells Current Protocols in Stem Cell Biology. May, 2009 | Pubmed ID: 19455542 The Dynamics of Long-term Transgene Expression in Engrafted Neural Stem Cells The Journal of Comparative Neurology. Jul, 2009 | Pubmed ID: 19399895 Neuroimaging As a Basis for Rational Stem Cell Therapy Pediatric Neurology. Mar, 2009 | Pubmed ID: 19218036 Discovery of a Functional Protein Complex of Netrin-4, Laminin Gamma1 Chain, and Integrin Alpha6beta1 in Mouse Neural Stem Cells Proceedings of the National Academy of Sciences of the United States of America. Feb, 2009 | Pubmed ID: 19193855 Role of Monocyte Chemoattractant Protein-1 (MCP-1/CCL2) in Migration of Neural Progenitor Cells Toward Glial Tumors Journal of Neuroscience Research. May, 2009 | Pubmed ID: 19125409 Neural Precursor Cell Lines Promote Neurite Branching The International Journal of Neuroscience. 2009 | Pubmed ID: 19116829 Neural Stem/progenitor Cells Modulate Immune Responses by Suppressing T Lymphocytes with Nitric Oxide and Prostaglandin E2 Experimental Neurology. Mar, 2009 | Pubmed ID: 19109951 Preparation of Autogenic Human Feeder Cells for Growth of Human Embryonic Stem Cells Current Protocols in Stem Cell Biology. Mar, 2008 | Pubmed ID: 18770638 Neural Stem Cell Delivery to the Spinal Cord in an Ovine Model of Fetal Surgery for Spina Bifida Surgery. Sep, 2008 | Pubmed ID: 18707035 Inflammation As a Matchmaker: Revisiting Cell Fusion Nature Cell Biology. May, 2008 | Pubmed ID: 18454127 Neural Stem Cell Transplantation in Mouse Brain Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [et Al.]. Jan, 2008 | Pubmed ID: 18428671 Human Neural Stem Cells Migrate Along the Nigrostriatal Pathway in a Primate Model of Parkinson's Disease Experimental Neurology. Jun, 2008 | Pubmed ID: 18394605 Brain Tumor Stem Cells and the Tumor Microenvironmen Neurosurgical Focus. 2008 | Pubmed ID: 18341404 Stem Cell-mediated Regeneration of the Intervertebral Disc: Cellular and Molecular Challenge Neurosurgical Focus. 2008 | Pubmed ID: 18341398 Genetic Modification of Neural Stem Cells Molecular Therapy : the Journal of the American Society of Gene Therapy. Mar, 2008 | Pubmed ID: 18253153 Quo Vadis Brain Repair? A Long Axonal Journey in the Adult CNS Cell Stem Cell. Oct, 2007 | Pubmed ID: 18371370 Neural Progenitor Cell Transplantation and Imaging in a Large Animal Model Neuroscience Research. Nov, 2007 | Pubmed ID: 17897743 Neural Stem Cell Implantation Extends Life in Niemann-Pick C1 Mice Journal of Applied Genetics. 2007 | Pubmed ID: 17666780 Neural Stem Cells Injected into the Sound-damaged Cochlea Migrate Throughout the Cochlea and Express Markers of Hair Cells, Supporting Cells, and Spiral Ganglion Cells Hearing Research. Oct, 2007 | Pubmed ID: 17659854 Behavioral Improvement in a Primate Parkinson's Model is Associated with Multiple Homeostatic Effects of Human Neural Stem Cells Proceedings of the National Academy of Sciences of the United States of America. Jul, 2007 | Pubmed ID: 17586681 A Novel, Immortal, and Multipotent Human Neural Stem Cell Line Generating Functional Neurons and Oligodendrocytes Stem Cells (Dayton, Ohio). Sep, 2007 | Pubmed ID: 17556596 Stem Cells Act Through Multiple Mechanisms to Benefit Mice with Neurodegenerative Metabolic Disease Nature Medicine. Apr, 2007 | Pubmed ID: 17351625 Injection of Mouse and Human Neural Stem Cells into Neonatal Niemann-Pick A Model Mice Brain Research. Apr, 2007 | Pubmed ID: 17289003 Isolation of Amniotic Stem Cell Lines with Potential for Therapy Nature Biotechnology. Jan, 2007 | Pubmed ID: 17206138 The Leading Edge of Stem Cell Therapeutics Annual Review of Medicine. 2007 | Pubmed ID: 17100553 Large Animal Models Are Critical for Rationally Advancing Regenerative Therapies Regenerative Medicine. Jul, 2006 | Pubmed ID: 17465832 Physical Activity-mediated Functional Recovery After Spinal Cord Injury: Potential Roles of Neural Stem Cells Regenerative Medicine. Nov, 2006 | Pubmed ID: 17465758 Immunomodulatory Neural Stem Cells for Brain Tumour Therapy Expert Opinion on Biological Therapy. Dec, 2006 | Pubmed ID: 17223735 Neural Stem Cell Transplant Survival in Brains of Mice: Assessing the Effect of Immunity and Ischemia by Using Real-time Bioluminescent Imaging Radiology. Dec, 2006 | Pubmed ID: 17114629 Adhesive Interactions Between Human Neural Stem Cells and Inflamed Human Vascular Endothelium Are Mediated by Integrins Stem Cells (Dayton, Ohio). Nov, 2006 | Pubmed ID: 17071855 Defining the Actual Sensitivity and Specificity of the Neurosphere Assay in Stem Cell Biology Nature Methods. Oct, 2006 | Pubmed ID: 16990812 Neural Stem Cells Rescue Nervous Purkinje Neurons by Restoring Molecular Homeostasis of Tissue Plasminogen Activator and Downstream Targets The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jul, 2006 | Pubmed ID: 16870729 Cryopreservation by Slow Cooling with DMSO Diminished Production of Oct-4 Pluripotency Marker in Human Embryonic Stem Cells Cryobiology. Oct, 2006 | Pubmed ID: 16839540 Intrinsic Resistance of Neural Stem Cells to Toxic Metabolites May Make Them Well Suited for Cell Non-autonomous Disorders: Evidence from a Mouse Model of Krabbe Leukodystrophy Journal of Neurochemistry. Jun, 2006 | Pubmed ID: 16805770 Special Issue: the Intersection of Stem/progenitor Cell Biology and Hypoxic-ischemic Cerebral Injury/stroke Experimental Neurology. May, 2006 | Pubmed ID: 16798271 Acute Injury Directs the Migration, Proliferation, and Differentiation of Solid Organ Stem Cells: Evidence from the Effect of Hypoxia-ischemia in the CNS on Clonal "reporter" Neural Stem Cells Experimental Neurology. May, 2006 | Pubmed ID: 16737696 Human Neurospheres Derived from the Fetal Central Nervous System Are Regionally and Temporally Specified but Are Not Committed Experimental Neurology. May, 2006 | Pubmed ID: 16714017 Neural Stem Cells May Be Uniquely Suited for Combined Gene Therapy and Cell Replacement: Evidence from Engraftment of Neurotrophin-3-expressing Stem Cells in Hypoxic-ischemic Brain Injury Experimental Neurology. May, 2006 | Pubmed ID: 16714016 Neural Stem Cells As Novel Cancer Therapeutic Vehicles European Journal of Cancer (Oxford, England : 1990). Jun, 2006 | Pubmed ID: 16697638 Purkinje Neuron Degeneration in Nervous (nr) Mutant Mice is Mediated by a Metabolic Pathway Involving Excess Tissue Plasminogen Activator Proceedings of the National Academy of Sciences of the United States of America. May, 2006 | Pubmed ID: 16682647 Neural Progenitor Cells Engineered to Secrete GDNF Show Enhanced Survival, Neuronal Differentiation and Improve Cognitive Function Following Traumatic Brain Injury The European Journal of Neuroscience. Apr, 2006 | Pubmed ID: 16630059 Can Science Resolve the Ethical Impasse in Stem Cell Research? Nature Biotechnology. Apr, 2006 | Pubmed ID: 16601717 Beyond Fraud--stem-cell Research Continues The New England Journal of Medicine. Jan, 2006 | Pubmed ID: 16436761 Networks of Gold Nanoparticles and Bacteriophage As Biological Sensors and Cell-targeting Agents Proceedings of the National Academy of Sciences of the United States of America. Jan, 2006 | Pubmed ID: 16434473 Therapeutic Effects of Clenbuterol in a Murine Model of Amyotrophic Lateral Sclerosis Neuroscience Letters. Apr 10-17, 2006 | Pubmed ID: 16388902 Gene Therapy: Can Neural Stem Cells Deliver? Nature Reviews. Neuroscience. Jan, 2006 | Pubmed ID: 16371952 Exploring Common Ground in the Stem Cell Ethical Debate--a Perspective for Scientists: Introduction to This Special Issue of Stem Cell Reviews Stem Cell Reviews. Dec, 2005 | Pubmed ID: 17142867 Caspase-mediated Cell Death Predominates Following Engraftment of Neural Progenitor Cells into Traumatically Injured Rat Brain Brain Research. Dec, 2005 | Pubmed ID: 16309635 A Role for Stem Cell Biology in the Physiological and Pathological Aspects of Aging Journal of the American Geriatrics Society. Sep, 2005 | Pubmed ID: 16131354 Expression Profile of an Operationally-defined Neural Stem Cell Clone Experimental Neurology. Aug, 2005 | Pubmed ID: 15992799 Neural Stem Cells Implanted into MPTP-treated Monkeys Increase the Size of Endogenous Tyrosine Hydroxylase-positive Cells Found in the Striatum: a Return to Control Measures Cell Transplantation. 2005 | Pubmed ID: 15929553 A Review and Rationale for the Use of Cellular Transplantation As a Therapeutic Strategy for Traumatic Brain Injury Journal of Neurotrauma. Nov, 2004 | Pubmed ID: 15684646 Directed Migration of Neural Stem Cells to Sites of CNS Injury by the Stromal Cell-derived Factor 1alpha/CXC Chemokine Receptor 4 Pathway Proceedings of the National Academy of Sciences of the United States of America. Dec, 2004 | Pubmed ID: 15608062 Neural Stem Cells Protect Against Glutamate-induced Excitotoxicity and Promote Survival of Injured Motor Neurons Through the Secretion of Neurotrophic Factors Molecular and Cellular Neurosciences. Nov, 2004 | Pubmed ID: 15519246 Differentiation and Tropic/trophic Effects of Exogenous Neural Precursors in the Adult Spinal Cord The Journal of Comparative Neurology. Nov, 2004 | Pubmed ID: 15514921 Stem Cells: Cross-talk and Developmental Programs Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. May, 2004 | Pubmed ID: 15293810 Neural Stem/progenitor Cells Express Costimulatory Molecules That Are Differentially Regulated by Inflammatory and Apoptotic Stimuli The American Journal of Pathology. May, 2004 | Pubmed ID: 15111308 Taking Stock and Planning for the Next Decade: Realistic Prospects for Stem Cell Therapies for the Nervous System Journal of Neuroscience Research. Apr, 2004 | Pubmed ID: 15048913 Reality and Immortality--neural Stem Cells for Therapies Nature Biotechnology. Mar, 2004 | Pubmed ID: 14990948 Minocycline Inhibits Contusion-triggered Mitochondrial Cytochrome C Release and Mitigates Functional Deficits After Spinal Cord Injury Proceedings of the National Academy of Sciences of the United States of America. Mar, 2004 | Pubmed ID: 14981254 Fate of Multipotent Neural Precursor Cells Transplanted into Mouse Retina Selectively Depleted of Retinal Ganglion Cells Experimental Neurology. Mar, 2004 | Pubmed ID: 14980806 Constitutive EGFR Signaling Confers a Motile Phenotype to Neural Stem Cells Molecular and Cellular Neurosciences. Dec, 2003 | Pubmed ID: 14697673 Realistic Prospects for Stem Cell Therapeutics Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program. 2003 | Pubmed ID: 14633792 Neural Stem Cell Biology May Be Well Suited for Improving Brain Tumor Therapies Cancer Journal (Sudbury, Mass.). May-Jun, 2003 | Pubmed ID: 12952304 Genetic Programs and Responses of Neural Stem/progenitor Cells During Demyelination: Potential Insights into Repair Mechanisms in Multiple Sclerosis Physiological Genomics. Aug, 2003 | Pubmed ID: 12923300 Neural Stem Cells for CNS Repair: State of the Art and Future Directions Advances in Experimental Medicine and Biology. 2002 | Pubmed ID: 12614070 Neural Stem Cells Spontaneously Express Dopaminergic Traits After Transplantation into the Intact or 6-hydroxydopamine-lesioned Rat Experimental Neurology. Sep, 2002 | Pubmed ID: 12429210 The Injured Brain Interacts Reciprocally with Neural Stem Cells Supported by Scaffolds to Reconstitute Lost Tissue Nature Biotechnology. Nov, 2002 | Pubmed ID: 12379868 Neural Stem Cells Display an Inherent Mechanism for Rescuing Dysfunctional Neurons Nature Biotechnology. Nov, 2002 | Pubmed ID: 12379867 Transplanted Neural Stem Cells Survive, Differentiate, and Improve Neurological Motor Function After Experimental Traumatic Brain Injury Neurosurgery. Oct, 2002 | Pubmed ID: 12234415 Limitations in Brain Repair Nature Medicine. Sep, 2002 | Pubmed ID: 12205449 Transplanted Clonal Neural Stem-like Cells Respond to Remote Photic Stimulation Following Incorporation Within the Suprachiasmatic Nucleus Experimental Neurology. Apr, 2002 | Pubmed ID: 11922658 Functional Recovery Following Traumatic Spinal Cord Injury Mediated by a Unique Polymer Scaffold Seeded with Neural Stem Cells Proceedings of the National Academy of Sciences of the United States of America. Mar, 2002 | Pubmed ID: 11867737 Generation of 3D Whole Lung Organoids from Induced Pluripotent Stem Cells for Modeling Lung Developmental Biology and Disease Sandra L. Leibel1,2,3, Rachael N. McVicar2,3, Alicia M. Winquist2,3, Evan Y. Snyder1,2,3 1Department of Pediatrics, University of California, San Diego School of Medicine, 2Sanford Consortium for Regenerative Medicine, 3Sanford Burnham Prebys Medical Discovery Institute JoVE 62456 Biologia dello sviluppo Efficient Derivation of Human Cardiac Precursors and Cardiomyocytes from Pluripotent Human Embryonic Stem Cells with Small Molecule Induction Xuejun H. Parsons1,2, Yang D. Teng3,4, James F. Parsons1,2, Evan Y. Snyder1,2,5, David B. Smotrich1,2,6, Dennis A. Moore1,2 1San Diego Regenerative Medicine Institute, 2Xcelthera, 3Department of Neurosurgery, Harvard Medical School, 4Division of SCI Research, VA Boston Healthcare System, 5Program in Stem Cell & Regenerative Biology, Sanford-Burnham Medical Research Institute, 6La Jolla IVF JoVE 3274 Biologia Efficient Derivation of Human Neuronal Progenitors and Neurons from Pluripotent Human Embryonic Stem Cells with Small Molecule Induction Xuejun H. Parsons1,2, Yang D. Teng3,4, James F. Parsons1,2, Evan Y. Snyder1,2,5, David B. Smotrich1,2,6, Dennis A. Moore1,2 1San Diego Regenerative Medicine Institute, 2Xcelthera, 3Department of Neurosurgery, Harvard Medical School, 4Division of SCI Research, VA Boston Healthcare System, 5Program in Stem Cell & Regenerative Biology, Sanford-Burnham Medical Research Institute, 6La Jolla IVF JoVE 3273 Neuroscienze
Generation of 3D Whole Lung Organoids from Induced Pluripotent Stem Cells for Modeling Lung Developmental Biology and Disease Sandra L. Leibel1,2,3, Rachael N. McVicar2,3, Alicia M. Winquist2,3, Evan Y. Snyder1,2,3 1Department of Pediatrics, University of California, San Diego School of Medicine, 2Sanford Consortium for Regenerative Medicine, 3Sanford Burnham Prebys Medical Discovery Institute JoVE 62456 Biologia dello sviluppo
Efficient Derivation of Human Cardiac Precursors and Cardiomyocytes from Pluripotent Human Embryonic Stem Cells with Small Molecule Induction Xuejun H. Parsons1,2, Yang D. Teng3,4, James F. Parsons1,2, Evan Y. Snyder1,2,5, David B. Smotrich1,2,6, Dennis A. Moore1,2 1San Diego Regenerative Medicine Institute, 2Xcelthera, 3Department of Neurosurgery, Harvard Medical School, 4Division of SCI Research, VA Boston Healthcare System, 5Program in Stem Cell & Regenerative Biology, Sanford-Burnham Medical Research Institute, 6La Jolla IVF JoVE 3274 Biologia
Efficient Derivation of Human Neuronal Progenitors and Neurons from Pluripotent Human Embryonic Stem Cells with Small Molecule Induction Xuejun H. Parsons1,2, Yang D. Teng3,4, James F. Parsons1,2, Evan Y. Snyder1,2,5, David B. Smotrich1,2,6, Dennis A. Moore1,2 1San Diego Regenerative Medicine Institute, 2Xcelthera, 3Department of Neurosurgery, Harvard Medical School, 4Division of SCI Research, VA Boston Healthcare System, 5Program in Stem Cell & Regenerative Biology, Sanford-Burnham Medical Research Institute, 6La Jolla IVF JoVE 3273 Neuroscienze