Gary Clawson Departments of Pathology, and Biochemistry and Molecular Biology, Hershey Medical Center Pennsylvania State University Biography Publications Institution JoVE Articles Gary Clawson has not added a biography. If you are Gary Clawson and would like to personalize this page please email our Author Liaison for assistance. Publications Identification of Mammary Epithelial Cells Subject to Chronic Oxidative Stress in Mammary Epithelium of Young Women and Teenagers Living in USA: Implication for Breast Carcinogenesis Cancer Biology & Therapy. Jan, 2012 | Pubmed ID: 22231390 Nanoresonator Chip-based RNA Sensor Strategy for Detection of Circulating Tumor Cells: Response Using PCA3 As a Prostate Cancer Marker Nanomedicine : Nanotechnology, Biology, and Medicine. Nov, 2011 | Pubmed ID: 22115599 Primer-free Aptamer Selection Using a Random DNA Library Methods in Molecular Biology (Clifton, N.J.). 2010 | Pubmed ID: 20387162 MicroRNAs Align with Accessible Sites in Target MRNAs Journal of Cellular Biochemistry. Feb, 2010 | Pubmed ID: 19998415 An RNA Sensor Platform for CTC Detection: Nanotechnology for Detection of Tumour Cell Marker RNAs BIOforum Europe : Trends and Techniques in Life Science Research. Feb, 2009 | Pubmed ID: 21278810 Mechanisms of Growth Inhibition in Human Papillomavirus Positive and Negative Cervical Cancer Cells by the Chloromethyl Ketone Protease Inhibitor, Succinyl-alanine-alanine-proline-phenylalanine Chloromethyl Ketone The Journal of Pharmacology and Experimental Therapeutics. Jul, 2009 | Pubmed ID: 19401497 The Shorter the Better: Reducing Fixed Primer Regions of Oligonucleotide Libraries for Aptamer Selection Molecules (Basel, Switzerland). 2009 | Pubmed ID: 19384268 Altered Gene Expression in Breast Cancer Liver Metastases International Journal of Cancer. Journal International Du Cancer. Apr, 2009 | Pubmed ID: 19117052 Catalytic DNAzymes: Derivations and Functions Expert Opinion on Biological Therapy. Aug, 2008 | Pubmed ID: 18613760 Vagotomy Enhances Experimental Metastases of 4THMpc Breast Cancer Cells and Alters Substance P Level Regulatory Peptides. Nov, 2008 | Pubmed ID: 18499282 Intracellular Localization of the Tumor Suppressor HtrA1/Prss11 and Its Association with HPV16 E6 and E7 Proteins Journal of Cellular Biochemistry. Sep, 2008 | Pubmed ID: 18452160 Minimal Primer and Primer-free SELEX Protocols for Selection of Aptamers from Random DNA Libraries BioTechniques. Mar, 2008 | Pubmed ID: 18361789 IGF-1 Induces SREBP-1 Expression and Lipogenesis in SEB-1 Sebocytes Via Activation of the Phosphoinositide 3-kinase/Akt Pathway The Journal of Investigative Dermatology. May, 2008 | Pubmed ID: 17989724 Systemic Targeting Inhibitor of KappaB Kinase Inhibits Melanoma Tumor Growth Cancer Research. Apr, 2007 | Pubmed ID: 17409419 The Chloromethylketone Protease Inhibitor AAPF(CMK) Also Targets ATP-dependent Helicases and SAP-domain Proteins Journal of Cellular Biochemistry. Feb, 2007 | Pubmed ID: 17006953 Identifying Accessible Sites in RNA: the First Step in Designing Antisense Reagents Current Medicinal Chemistry. 2006 | Pubmed ID: 17073649 Capsaicin-induced Inactivation of Sensory Neurons Promotes a More Aggressive Gene Expression Phenotype in Breast Cancer Cells Breast Cancer Research and Treatment. Oct, 2006 | Pubmed ID: 16583263 Insulin-like Growth Factor-1 Induces Lipid Production in Human SEB-1 Sebocytes Via Sterol Response Element-binding Protein-1 The Journal of Investigative Dermatology. Jun, 2006 | Pubmed ID: 16575389 A Protease Inhibitor Specifically Inhibits Growth of HPV-infected Keratinocytes Molecular Therapy : the Journal of the American Society of Gene Therapy. Jun, 2006 | Pubmed ID: 16564747 Antisense Applications for Biological Control Journal of Cellular Biochemistry. May, 2006 | Pubmed ID: 16440307 Comparison of Cryopreservation and Standard Needle Biopsy for Gene Expression Profiling of Human Breast Cancer Specimens Breast Cancer Research and Treatment. Mar, 2005 | Pubmed ID: 15770532 Parameters Affecting Substance P Measurement in Heart, Lung, and Skin BioTechniques. Aug, 2004 | Pubmed ID: 15335215 Spontaneous Transformation of an Immortalized Hepatocyte Cell Line: Potential Role of a Nuclear Protease Cancer Letters. Sep, 2004 | Pubmed ID: 15312682 Capsaicin-mediated Denervation of Sensory Neurons Promotes Mammary Tumor Metastasis to Lung and Heart Anticancer Research. Mar-Apr, 2004 | Pubmed ID: 15161056 A Self-processing Ribozyme Cassette: Utility Against Human Papillomavirus 11 E6/E7 MRNA and Hepatitis B Virus Molecular Therapy : the Journal of the American Society of Gene Therapy. Apr, 2004 | Pubmed ID: 15093190 Identification of Efficient Cleavage Sites in Long-target RNAs Methods in Molecular Biology (Clifton, N.J.). 2004 | Pubmed ID: 15017046 Human Skin is a Steroidogenic Tissue: Steroidogenic Enzymes and Cofactors Are Expressed in Epidermis, Normal Sebocytes, and an Immortalized Sebocyte Cell Line (SEB-1) The Journal of Investigative Dermatology. Jun, 2003 | Pubmed ID: 12787114 Rapid Identification of Efficient Target Cleavage Sites Using a Hammerhead Ribozyme Library in an Iterative Manner Molecular Therapy : the Journal of the American Society of Gene Therapy. Jan, 2003 | Pubmed ID: 12573626 Involvement of the Fungal Nuclear Migration Gene NudC Human Homolog in Cell Proliferation and Mitotic Spindle Formation Experimental Cell Research. Feb, 2002 | Pubmed ID: 11795948 Primer-Free Aptamer Selection Using A Random DNA Library Weihua Pan1, Ping Xin1, Susan Patrick1, Stacey Dean2, Christine Keating2, Gary Clawson3,4 1Department of Pathology, Hershey Medical Center, Pennsylvania State University, 2Department of Chemistry, Pennsylvania State University, 3Departments of Pathology, and Biochemistry and Molecular Biology, Hershey Medical Center, Pennsylvania State University, 4Materials Research Institute, Pennsylvania State University JoVE 2039 Biologia
Primer-Free Aptamer Selection Using A Random DNA Library Weihua Pan1, Ping Xin1, Susan Patrick1, Stacey Dean2, Christine Keating2, Gary Clawson3,4 1Department of Pathology, Hershey Medical Center, Pennsylvania State University, 2Department of Chemistry, Pennsylvania State University, 3Departments of Pathology, and Biochemistry and Molecular Biology, Hershey Medical Center, Pennsylvania State University, 4Materials Research Institute, Pennsylvania State University JoVE 2039 Biologia