Gerard Apodaca Renal-Electrolyte Division, Department of Medicine University of Pittsburgh Biography Publications Institution JoVE Articles Gerard Apodaca has not added a biography. If you are Gerard Apodaca and would like to personalize this page please email our Author Liaison for assistance. Publications Studies of Ultrastructure, Gene Expression, and Marker Analysis Reveal That Mouse Bladder PDGFRA Interstitial Cells Are Fibroblasts American Journal of Physiology. Renal Physiology. 09, 2022 | Pubmed ID: 35834272 The Molecular Chaperone GRP170 Protects Against ER Stress and Acute Kidney Injury in Mice JCI Insight. 03, 2022 | Pubmed ID: 35104250 Bladder Infection with Uropathogenic Increases the Excitability of Afferent Neurons American Journal of Physiology. Renal Physiology. 01, 2022 | Pubmed ID: 34779263 Functional Roles for PIEZO1 and PIEZO2 in Urothelial Mechanotransduction and Lower Urinary Tract Interoception JCI Insight. 10, 2021 | Pubmed ID: 34464353 3D Printed Biaxial Stretcher Compatible with Live Fluorescence Microscopy HardwareX. Apr, 2020 | Pubmed ID: 35097243 The Urothelium: Life in a Liquid Environment Physiological Reviews. 10, 2020 | Pubmed ID: 32191559 Expansion and Contraction of the Umbrella Cell Apical Junctional Ring in Response to Bladder Filling and Voiding Molecular Biology of the Cell. 07, 2019 | Pubmed ID: 31166831 Expression and Distribution of PIEZO1 in the Mouse Urinary Tract American Journal of Physiology. Renal Physiology. Aug, 2019 | Pubmed ID: 31166705 Acute Spinal Cord Injury is Associated with Mitochondrial Dysfunction in Mouse Urothelium Neurourology and Urodynamics. 08, 2019 | Pubmed ID: 31102563 Urinary K Promotes Irritative Voiding Symptoms and Pain in the Face of Urothelial Barrier Dysfunction Scientific Reports. 04, 2019 | Pubmed ID: 30940909 Corrigendum: Inflammation and Tissue Remodeling in the Bladder and Urethra in Feline Interstitial Cystitis Frontiers in Systems Neuroscience. 2018 | Pubmed ID: 30459568 Age-related Endolysosome Dysfunction in the Rat Urothelium PloS One. 2018 | Pubmed ID: 29883476 Generation of Three-dimensional Human Neuronal Cultures: Application to Modeling CNS Viral Infections Stem Cell Research & Therapy. 05, 2018 | Pubmed ID: 29751846 Inflammation and Tissue Remodeling in the Bladder and Urethra in Feline Interstitial Cystitis Frontiers in Systems Neuroscience. 2018 | Pubmed ID: 29706873 RAB27B Requirement for Stretch-induced Exocytosis in Bladder Umbrella Cells American Journal of Physiology. Cell Physiology. 03, 2018 | Pubmed ID: 29167152 Role of Polarity Proteins in the Generation and Organization of Apical Surface Protrusions Cold Spring Harbor Perspectives in Biology. 01, 2018 | Pubmed ID: 28264821 Low-Density Neuronal Cultures from Human Induced Pluripotent Stem Cells Molecular Neuropsychiatry. Jul, 2017 | Pubmed ID: 28879199 Urothelial Proliferation and Regeneration After Spinal Cord Injury American Journal of Physiology. Renal Physiology. 07, 2017 | Pubmed ID: 28331065 Convergent Signaling Pathways Regulate Parathyroid Hormone and Fibroblast Growth Factor-23 Action on NPT2A-mediated Phosphate Transport The Journal of Biological Chemistry. 09, 2016 | Pubmed ID: 27432882 Increased Urothelial Paracellular Transport Promotes Cystitis American Journal of Physiology. Renal Physiology. Dec, 2015 | Pubmed ID: 26423859 Measuring Receptor Recycling in Polarized MDCK Cells Methods in Cell Biology. 2015 | Pubmed ID: 26360039 Membrane Traffic Research: Challenges for the Next Decade Frontiers in Cell and Developmental Biology. 2014 | Pubmed ID: 25364759 A1 Adenosine Receptor-stimulated Exocytosis in Bladder Umbrella Cells Requires Phosphorylation of ADAM17 Ser-811 and EGF Receptor Transactivation Molecular Biology of the Cell. Nov, 2014 | Pubmed ID: 25232008 TBC1D9B Functions As a GTPase-activating Protein for Rab11a in Polarized MDCK Cells Molecular Biology of the Cell. Nov, 2014 | Pubmed ID: 25232007 A Phosphotyrosine Switch for Cargo Sequestration at Clathrin-coated Buds The Journal of Biological Chemistry. Jun, 2014 | Pubmed ID: 24798335 Bladder Filling and Voiding Affect Umbrella Cell Tight Junction Organization and Function American Journal of Physiology. Renal Physiology. Oct, 2013 | Pubmed ID: 23884145 A Rab11a-Rab8a-Myo5B Network Promotes Stretch-regulated Exocytosis in Bladder Umbrella Cells Molecular Biology of the Cell. Apr, 2013 | Pubmed ID: 23389633 PIP5KIβ Selectively Modulates Apical Endocytosis in Polarized Renal Epithelial Cells PloS One. 2013 | Pubmed ID: 23342003 Role of Membrane Traffic in the Generation of Epithelial Cell Asymmetry Nature Cell Biology. Dec, 2012 | Pubmed ID: 23196841 The Epithelial Sodium Channel (ENaC) Establishes a Trafficking Vesicle Pool Responsible for Its Regulation PloS One. 2012 | Pubmed ID: 23029554 Exigence Pour Une Protéine De Type 3 a Uroplakin Dans Le Développement De La Fonction De Cellules épithéliales Tubule Pronephric Zebrafish, Morphogenèse Et Polarité PloS One. 2012 | Pubmed ID: 22848617 La Phosphorylation De Rab11-FIP2 Réglemente La Polarité Dans Les Cellules MDCK Molecular Biology of the Cell. Jun, 2012 | Pubmed ID: 22553350 Modulation of Bladder Function by Luminal Adenosine Turnover and A1 Receptor Activation American Journal of Physiology. Renal Physiology. Jul, 2012 | Pubmed ID: 22552934 Rab11b Regulates the Trafficking and Recycling of the Epithelial Sodium Channel (ENaC) American Journal of Physiology. Renal Physiology. Mar, 2012 | Pubmed ID: 22129970 Galectin-7 Modulates the Length of the Primary Cilia and Wound Repair in Polarized Kidney Epithelial Cells American Journal of Physiology. Renal Physiology. Sep, 2011 | Pubmed ID: 21677144 Expression and Distribution of Transient Receptor Potential (TRP) Channels in Bladder Epithelium American Journal of Physiology. Renal Physiology. Jan, 2011 | Pubmed ID: 20943764 Compensatory Endocytosis in Bladder Umbrella Cells Occurs Through an Integrin-regulated and RhoA- and Dynamin-dependent Pathway The EMBO Journal. Jun, 2010 | Pubmed ID: 20461056 Cell Biology and Physiology of the Uroepithelium American Journal of Physiology. Renal Physiology. Dec, 2009 | Pubmed ID: 19587142 Distinct Apical and Basolateral Membrane Requirements for Stretch-induced Membrane Traffic at the Apical Surface of Bladder Umbrella Cells Molecular Biology of the Cell. Jan, 2009 | Pubmed ID: 18987341 Rab11a-dependent Exocytosis of Discoidal/fusiform Vesicles in Bladder Umbrella Cells Proceedings of the National Academy of Sciences of the United States of America. Oct, 2008 | Pubmed ID: 18843107 Urinary Bladder Function and Somatic Sensitivity in Vasoactive Intestinal Polypeptide (VIP)-/- Mice Journal of Molecular Neuroscience : MN. Nov, 2008 | Pubmed ID: 18561033 Transcytosis of Polymeric Immunoglobulin a in Polarized Madin-Darby Canine Kidney Cells Methods in Molecular Biology (Clifton, N.J.). 2008 | Pubmed ID: 18369944 Studies on Localization and Function of Annexin A4a Within Urinary Bladder Epithelium Using a Mouse Knockout Model American Journal of Physiology. Renal Physiology. Apr, 2008 | Pubmed ID: 18256316 Exocyst Requirement for Endocytic Traffic Directed Toward the Apical and Basolateral Poles of Polarized MDCK Cells Molecular Biology of the Cell. Oct, 2007 | Pubmed ID: 17686995 Differential Involvement of Endocytic Compartments in the Biosynthetic Traffic of Apical Proteins The EMBO Journal. Aug, 2007 | Pubmed ID: 17673908 The Uroepithelial-associated Sensory Web Kidney International. Nov, 2007 | Pubmed ID: 17667988 Defective CFTR Apical Endocytosis and Enterocyte Brush Border in Myosin VI-deficient Mice Traffic (Copenhagen, Denmark). Aug, 2007 | Pubmed ID: 17555536 RhoB-dependent Modulation of Postendocytic Traffic in Polarized Madin-Darby Canine Kidney Cells Traffic (Copenhagen, Denmark). Jul, 2007 | Pubmed ID: 17547697 Apical Epidermal Growth Factor Receptor Signaling: Regulation of Stretch-dependent Exocytosis in Bladder Umbrella Cells Molecular Biology of the Cell. Apr, 2007 | Pubmed ID: 17287395 WITHDRAWN: RhoB-dependent Modulation of Early Endocytic Traffic in Madin-Darby Canine Kidney Cells The Journal of Biological Chemistry. Jun, 2007 | Pubmed ID: 15319429 Mark2/EMK1/Par-1Balpha La Phosphorylation De La Protéine D'interaction Rab11-famille 2 Est Nécessaire Pour La Mise En Place En Temps Opportun De Polarité Dans Les Cellules Madin-Darby Canine Kidney Molecular Biology of the Cell. Aug, 2006 | Pubmed ID: 16775013 ATP and Purinergic Receptor-dependent Membrane Traffic in Bladder Umbrella Cells The Journal of Clinical Investigation. Sep, 2005 | Pubmed ID: 16110327 Isolation and Characterization of the Xenopus Oocyte Plasma Membrane: a New Method for Studying Activity of Water and Solute Transporters American Journal of Physiology. Renal Physiology. Jul, 2005 | Pubmed ID: 15741609 Water and Solute Permeability of Rat Lung Caveolae: High Permeabilities Explained by Acyl Chain Unsaturation American Journal of Physiology. Cell Physiology. Jul, 2005 | Pubmed ID: 15728712 Selective Permeability Barrier to Urea in Shark Rectal Gland American Journal of Physiology. Renal Physiology. Jul, 2005 | Pubmed ID: 15727989 Endotoxin Inhibits Intestinal Epithelial Restitution Through Activation of Rho-GTPase and Increased Focal Adhesions The Journal of Biological Chemistry. Jun, 2004 | Pubmed ID: 15169791 The Uroepithelium: Not Just a Passive Barrier Traffic (Copenhagen, Denmark). Mar, 2004 | Pubmed ID: 15086788 Distribution of the Tight Junction Proteins ZO-1, Occludin, and Claudin-4, -8, and -12 in Bladder Epithelium American Journal of Physiology. Renal Physiology. Aug, 2004 | Pubmed ID: 15068973 Permeabilities of Teleost and Elasmobranch Gill Apical Membranes: Evidence That Lipid Bilayers Alone Do Not Account for Barrier Function American Journal of Physiology. Cell Physiology. Jul, 2004 | Pubmed ID: 14998788 Differing Roles of Mitochondrial Nitric Oxide Synthase in Cardiomyocytes and Urothelial Cells American Journal of Physiology. Heart and Circulatory Physiology. Jan, 2004 | Pubmed ID: 14684357 Analysis of Hydrostatic Pressure-induced Changes in Umbrella Cell Surface Area Methods (San Diego, Calif.). Jul, 2003 | Pubmed ID: 12798135 Hydrostatic Pressure-regulated Ion Transport in Bladder Uroepithelium American Journal of Physiology. Renal Physiology. Oct, 2003 | Pubmed ID: 12770841 Disruption of Bladder Epithelium Barrier Function After Spinal Cord Injury American Journal of Physiology. Renal Physiology. May, 2003 | Pubmed ID: 12527557 Immunoglobulin Transport Across Polarized Epithelial Cells Nature Reviews. Molecular Cell Biology. Dec, 2002 | Pubmed ID: 12461560 Manganese Superoxide Dismutase Gene Therapy Protects Against Irradiation-induced Cystitis American Journal of Physiology. Renal Physiology. Dec, 2002 | Pubmed ID: 12426235 Beta-adrenoceptor Agonists Stimulate Endothelial Nitric Oxide Synthase in Rat Urinary Bladder Urothelial Cells The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Sep, 2002 | Pubmed ID: 12223560 Plasma Membrane Ca2+-ATPase and NCX1 Na+/Ca2+ Exchanger Expression in Distal Convoluted Tubule Cells American Journal of Physiology. Renal Physiology. Jul, 2002 | Pubmed ID: 12060584 Stretch-regulated Exocytosis/endocytosis in Bladder Umbrella Cells Molecular Biology of the Cell. Mar, 2002 | Pubmed ID: 11907265 Modulation of Membrane Traffic by Mechanical Stimuli American Journal of Physiology. Renal Physiology. Feb, 2002 | Pubmed ID: 11788431 Na,K-ATPase Activity is Required for Formation of Tight Junctions, Desmosomes, and Induction of Polarity in Epithelial Cells Molecular Biology of the Cell. Dec, 2001 | Pubmed ID: 11739775 Cdc42-dependent Modulation of Tight Junctions and Membrane Protein Traffic in Polarized Madin-Darby Canine Kidney Cells Molecular Biology of the Cell. Aug, 2001 | Pubmed ID: 11514615 Endocytic Traffic in Polarized Epithelial Cells: Role of the Actin and Microtubule Cytoskeleton Traffic (Copenhagen, Denmark). Mar, 2001 | Pubmed ID: 11260520 A Novel Clathrin Homolog That Co-distributes with Cytoskeletal Components Functions in the Trans-Golgi Network The EMBO Journal. Jan, 2001 | Pubmed ID: 11226177 Sorting of Membrane and Fluid at the Apical Pole of Polarized Madin-Darby Canine Kidney Cells Molecular Biology of the Cell. Jun, 2000 | Pubmed ID: 10848634 Clathrin-mediated Endocytosis of MUC1 is Modulated by Its Glycosylation State Molecular Biology of the Cell. Mar, 2000 | Pubmed ID: 10712502 Selective Alterations in Biosynthetic and Endocytic Protein Traffic in Madin-Darby Canine Kidney Epithelial Cells Expressing Mutants of the Small GTPase Rac1 Molecular Biology of the Cell. Jan, 2000 | Pubmed ID: 10637309 Modulation of Endocytic Traffic in Polarized Madin-Darby Canine Kidney Cells by the Small GTPase RhoA Molecular Biology of the Cell. Dec, 1999 | Pubmed ID: 10588664 Selective Perturbation of Apical Membrane Traffic by Expression of Influenza M2, an Acid-activated Ion Channel, in Polarized Madin-darby Canine Kidney Cells Molecular Biology of the Cell. Sep, 1998 | Pubmed ID: 9725907 Essai de vide en temps réel Marianela G. Dalghi1, Nicolas Montalbetti1, Travis B. Wheeler2, Gerard Apodaca1, Marcelo D. Carattino1,2 1Renal-Electrolyte Division, Department of Medicine, University of Pittsburgh, 2Department of Cell Biology, University of Pittsburgh JoVE 64621 Comportamento Ex Vivo Analyse des transitoires Ca2+ activés mécaniquement dans les cellules urothéliales Marcelo D. Carattino1,2, Wily G. Ruiz1, Gerard Apodaca1,2 1Renal-Electrolyte Division, Department of Medicine, University of Pittsburgh, 2Department of Cell Biology, University of Pittsburgh JoVE 64532 Medicina
Essai de vide en temps réel Marianela G. Dalghi1, Nicolas Montalbetti1, Travis B. Wheeler2, Gerard Apodaca1, Marcelo D. Carattino1,2 1Renal-Electrolyte Division, Department of Medicine, University of Pittsburgh, 2Department of Cell Biology, University of Pittsburgh JoVE 64621 Comportamento
Ex Vivo Analyse des transitoires Ca2+ activés mécaniquement dans les cellules urothéliales Marcelo D. Carattino1,2, Wily G. Ruiz1, Gerard Apodaca1,2 1Renal-Electrolyte Division, Department of Medicine, University of Pittsburgh, 2Department of Cell Biology, University of Pittsburgh JoVE 64532 Medicina