Gijsbert M. Grotenbreg Whitehead Institute for Biomedical Research Biography Publications Institution JoVE Articles Gijsbert M. Grotenbreg has not added a biography. If you are Gijsbert M. Grotenbreg and would like to personalize this page please email our Author Liaison for assistance. Publications Sources of Diversity in T Cell Epitope Discovery Frontiers in Bioscience : a Journal and Virtual Library. 2012 | Pubmed ID: 21622218 Engineering T Cells Specific for a Dominant Severe Acute Respiratory Syndrome Coronavirus CD8 T Cell Epitope Journal of Virology. Oct, 2011 | Pubmed ID: 21813600 Stability Screening of Arrays of Major Histocompatibility Complexes on Combinatorially Encoded Flow Cytometry Beads The Journal of Biological Chemistry. Aug, 2011 | Pubmed ID: 21680737 Synthesis and Evaluation of Strand and Turn Modified Ring-extended Gramicidin S Derivatives Bioorganic & Medicinal Chemistry. Jun, 2011 | Pubmed ID: 21561781 Oligoproline Helices As Structurally Defined Scaffolds for Oligomeric G Protein-coupled Receptor Ligands Organic & Biomolecular Chemistry. Apr, 2010 | Pubmed ID: 20449493 Transnuclear Mice with Predefined T Cell Receptor Specificities Against Toxoplasma Gondii Obtained Via SCNT Science (New York, N.Y.). Apr, 2010 | Pubmed ID: 20378817 Differential Regulation of Effector- and Central-memory Responses to Toxoplasma Gondii Infection by IL-12 Revealed by Tracking of Tgd057-specific CD8+ T Cells PLoS Pathogens. Mar, 2010 | Pubmed ID: 20333242 Ring-extended Derivatives of Gramicidin S with Furanoid Sugar Amino Acids in the Turn Region Have Enhanced Antimicrobial Activity ChemMedChem. Dec, 2009 | Pubmed ID: 19862783 Structural and Biological Evaluation of Some Loloatin C Analogues Bioorganic & Medicinal Chemistry. Sep, 2009 | Pubmed ID: 19679485 Site-specific N- and C-terminal Labeling of a Single Polypeptide Using Sortases of Different Specificity Journal of the American Chemical Society. Aug, 2009 | Pubmed ID: 19610623 Lipid Modification of Proteins Through Sortase-catalyzed Transpeptidation Journal of the American Chemical Society. Dec, 2008 | Pubmed ID: 18989959 The CD8 T-cell Response Against Murine Gammaherpesvirus 68 is Directed Toward a Broad Repertoire of Epitopes from Both Early and Late Antigens Journal of Virology. Dec, 2008 | Pubmed ID: 18922872 Parasite Stage-specific Recognition of Endogenous Toxoplasma Gondii-derived CD8+ T Cell Epitopes The Journal of Infectious Diseases. Dec, 2008 | Pubmed ID: 18922097 Discovery of CD8+ T Cell Epitopes in Chlamydia Trachomatis Infection Through Use of Caged Class I MHC Tetramers Proceedings of the National Academy of Sciences of the United States of America. Mar, 2008 | Pubmed ID: 18245382 Sortagging: a Versatile Method for Protein Labeling Nature Chemical Biology. Nov, 2007 | Pubmed ID: 17891153 Empty Class II Major Histocompatibility Complex Created by Peptide Photolysis Establishes the Role of DM in Peptide Association The Journal of Biological Chemistry. Jul, 2007 | Pubmed ID: 17525157 Double-stranded Helical Twisted Beta-sheet Channels in Crystals of Gramicidin S Grown in the Presence of Trifluoroacetic and Hydrochloric Acids Acta Crystallographica. Section D, Biological Crystallography. Mar, 2007 | Pubmed ID: 17327677 Beta-turn Modified Gramicidin S Analogues Containing Arylated Sugar Amino Acids Display Antimicrobial and Hemolytic Activity Comparable to the Natural Product Journal of the American Chemical Society. Jun, 2006 | Pubmed ID: 16756311 A Microengraving Method for Rapid Selection of Single Cells Producing Antigen-specific Antibodies Nature Biotechnology. Jun, 2006 | Pubmed ID: 16699501 Synthesis and Biological Evaluation of Gramicidin S Dimers Organic & Biomolecular Chemistry. Jan, 2005 | Pubmed ID: 15717418 Synthesis and Application of Carbohydrate-derived Morpholine Amino Acids The Journal of Organic Chemistry. Nov, 2004 | Pubmed ID: 15549804 A Practical Synthesis of Gramicidin S and Sugar Amino Acid Containing Analogues The Journal of Organic Chemistry. Nov, 2004 | Pubmed ID: 15527261 An Unusual Reverse Turn Structure Adopted by a Furanoid Sugar Amino Acid Incorporated in Gramicidin S Journal of the American Chemical Society. Mar, 2004 | Pubmed ID: 15025470 Synthesis and Biological Evaluation of Novel Turn-modified Gramicidin S Analogues Bioorganic & Medicinal Chemistry. Jul, 2003 | Pubmed ID: 12788356 Transnuclear Mice with Pre-defined T Cell Receptor Specificities Against Toxoplasma gondii Obtained Via SCNT Oktay Kirak1, Eva-Maria Frickel1, Gijsbert M. Grotenbreg1,2, Heikyung Suh1, Rudolf Jaenisch1,3, Hidde L. Ploegh1,3 1Whitehead Institute for Biomedical Research, 2Departments of Microbiology and Biological Sciences, National University of Singapore, 3Department of Biology, Massachusetts Institute of Technology JoVE 2168 Immunologia e infezioni
Transnuclear Mice with Pre-defined T Cell Receptor Specificities Against Toxoplasma gondii Obtained Via SCNT Oktay Kirak1, Eva-Maria Frickel1, Gijsbert M. Grotenbreg1,2, Heikyung Suh1, Rudolf Jaenisch1,3, Hidde L. Ploegh1,3 1Whitehead Institute for Biomedical Research, 2Departments of Microbiology and Biological Sciences, National University of Singapore, 3Department of Biology, Massachusetts Institute of Technology JoVE 2168 Immunologia e infezioni