Giovanna Tosato Laboratory of Cellular Oncology, Center for Cancer Research, National Cancer Institute National Institutes of Health Biography Publications Institution JoVE Articles Giovanna Tosato has not added a biography. If you are Giovanna Tosato and would like to personalize this page please email our Author Liaison for assistance. Publications Bone Marrow Niches in Myelodysplastic Syndromes Journal of Cancer Metastasis and Treatment. 2021 | Pubmed ID: 34746416 Targeting the SHP2 Phosphatase Promotes Vascular Damage and Inhibition of Tumor Growth EMBO Molecular Medicine. 07, 2021 | Pubmed ID: 34102002 Iterative Epigenomic Analyses in the Same Single Cell Genome Research. Oct, 2021 | Pubmed ID: 33627472 Vasculopathy and Coagulopathy Associated with SARS-CoV-2 Infection Cells. 06, 2020 | Pubmed ID: 32629875 Identification of Eph Receptor Signaling As a Regulator of Autophagy and a Therapeutic Target in Colorectal Carcinoma Molecular Oncology. 11, 2019 | Pubmed ID: 31545551 DLC1 Deficiency and YAP Signaling Drive Endothelial Cell Contact Inhibition of Growth and Tumorigenesis Oncogene. 11, 2019 | Pubmed ID: 31409902 Novel Insights into Endothelial Cell Malignancies Oncotarget. Dec, 2018 | Pubmed ID: 30680062 Effects of DLC1 Deficiency on Endothelial Cell Contact Growth Inhibition and Angiosarcoma Progression Journal of the National Cancer Institute. 04, 2018 | Pubmed ID: 29202196 Ephrin Ligands and Eph Receptors Contribution to Hematopoiesis Cellular and Molecular Life Sciences : CMLS. 09, 2017 | Pubmed ID: 28589441 Evidence for a Mesothelial Origin of Body Cavity Effusion Lymphomas Journal of the National Cancer Institute. 09, 2017 | Pubmed ID: 28376153 Burkitt Lymphoma Expresses Oncofetal Chondroitin Sulfate Without Being a Reservoir for Placental Malaria Sequestration International Journal of Cancer. 04, 2017 | Pubmed ID: 27997697 EphrinB2 Regulates the Emergence of a Hemogenic Endothelium from the Aorta Scientific Reports. 06, 2016 | Pubmed ID: 27250641 Identification of IL-23p19 As an Endothelial Proinflammatory Peptide That Promotes Gp130-STAT3 Signaling Science Signaling. Mar, 2016 | Pubmed ID: 26980441 Clinical Features and Outcomes of Patients With Symptomatic Kaposi Sarcoma Herpesvirus (KSHV)-associated Inflammation: Prospective Characterization of KSHV Inflammatory Cytokine Syndrome (KICS) Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America. Mar, 2016 | Pubmed ID: 26658701 Induction of Kaposi's Sarcoma-Associated Herpesvirus-Encoded Viral Interleukin-6 by X-Box Binding Protein 1 Journal of Virology. 01, 2016 | Pubmed ID: 26491160 EphrinB2 Controls Vessel Pruning Through STAT1-JNK3 Signalling Nature Communications. Mar, 2015 | Pubmed ID: 25807892 Contribution of Viral Mimics of Cellular Genes to KSHV Infection and Disease Viruses. Sep, 2014 | Pubmed ID: 25243371 Notch and TGFβ: Functional Partners Facilitating Tumor Progression Oncoimmunology. 2014 | Pubmed ID: 25114830 Tumor-infiltrating Myeloid Cells Activate Dll4/Notch/TGF-β Signaling to Drive Malignant Progression Cancer Research. Apr, 2014 | Pubmed ID: 24520074 GRANULOCYTE INFILTRATION AND EXPRESSION OF THE PRO-ANGIOGENIC BV8 PROTEIN IN EXPERIMENTAL EL4 AND LEWIS LUNG CARCINOMA TUMORS Cureus. Jan, 2013 | Pubmed ID: 25493215 Attenuation of Eph Receptor Kinase Activation in Cancer Cells by Coexpressed Ephrin Ligands PloS One. 2013 | Pubmed ID: 24348920 Human Herpesvirus 8+ Polyclonal IgMλ B-cell Lymphocytosis Mimicking Plasmablastic Leukemia/lymphoma in HIV-infected Patients European Journal of Haematology. Dec, 2013 | Pubmed ID: 23992152 Semaphorin 6A Regulates Angiogenesis by Modulating VEGF Signaling Blood. Nov, 2012 | Pubmed ID: 23007403 HHV-8-encoded Viral IL-6 Collaborates with Mouse IL-6 in the Development of Multicentric Castleman Disease in Mice Blood. May, 2012 | Pubmed ID: 22490805 PEGylation Potentiates the Effectiveness of an Antagonistic Peptide That Targets the EphB4 Receptor with Nanomolar Affinity PloS One. 2011 | Pubmed ID: 22194865 Viral Interleukin-6: Role in Kaposi's Sarcoma-associated Herpesvirus: Associated Malignancies Journal of Interferon & Cytokine Research : the Official Journal of the International Society for Interferon and Cytokine Research. Nov, 2011 | Pubmed ID: 21767154 Adult Human Circulating CD34â»Linâ»CD45â»CD133â» Cells Can Differentiate into Hematopoietic and Endothelial Cells Blood. Aug, 2011 | Pubmed ID: 21715308 NF-kappaB Activation Stimulates Transcription and Replication of Retrovirus XMRV in Human B-lineage and Prostate Carcinoma Cells Journal of Virology. Apr, 2011 | Pubmed ID: 21270144 Oligo-guanosine Nucleotide Induces Neuropilin-1 Internalization in Endothelial Cells and Inhibits Angiogenesis Blood. Oct, 2010 | Pubmed ID: 20606164 An Interleukin-6-related Systemic Inflammatory Syndrome in Patients Co-infected with Kaposi Sarcoma-associated Herpesvirus and HIV but Without Multicentric Castleman Disease Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America. Aug, 2010 | Pubmed ID: 20583924 The Transcription Factor Gfi1 Regulates G-CSF Signaling and Neutrophil Development Through the Ras Activator RasGRP1 Blood. May, 2010 | Pubmed ID: 20203268 Impaired Recruitment of Grk6 and Beta-Arrestin 2 Causes Delayed Internalization and Desensitization of a WHIM Syndrome-associated CXCR4 Mutant Receptor PloS One. Dec, 2009 | Pubmed ID: 19956569 The Tensin-3 Protein, Including Its SH2 Domain, is Phosphorylated by Src and Contributes to Tumorigenesis and Metastasis Cancer Cell. Sep, 2009 | Pubmed ID: 19732724 Regulation of Angiogenesis in Malignancies Associated with Epstein-Barr Virus and Kaposi's Sarcoma-associated Herpes Virus Future Microbiology. Sep, 2009 | Pubmed ID: 19722843 Targeting the Mammalian Target of Rapamycin to Inhibit VEGF and Cytokines for the Treatment of Primary Effusion Lymphoma Leukemia. Oct, 2009 | Pubmed ID: 19554030 EphrinB Reverse Signaling Contributes to Endothelial and Mural Cell Assembly into Vascular Structures Blood. Aug, 2009 | Pubmed ID: 19411631 Gene Regulation and Functional Alterations Induced by Kaposi's Sarcoma-associated Herpesvirus-encoded ORFK13/vFLIP in Endothelial Cells Journal of Virology. Mar, 2009 | Pubmed ID: 19091861 Palmitoylation Controls Recycling in Lysosomal Sorting and Trafficking Traffic (Copenhagen, Denmark). Nov, 2008 | Pubmed ID: 18817523 Dll4 Activation of Notch Signaling Reduces Tumor Vascularity and Inhibits Tumor Growth Blood. Sep, 2008 | Pubmed ID: 18577711 Sulfated Polysaccharides Identified As Inducers of Neuropilin-1 Internalization and Functional Inhibition of VEGF165 and Semaphorin3A Blood. Apr, 2008 | Pubmed ID: 18272814 Transcription Factor Gfi-1 Induced by G-CSF is a Negative Regulator of CXCR4 in Myeloid Cells Blood. Oct, 2007 | Pubmed ID: 17596540 FGF2 Posttranscriptionally Down-regulates Expression of SDF1 in Bone Marrow Stromal Cells Through FGFR1 IIIc Blood. Feb, 2007 | Pubmed ID: 17077327 EphB2 and EphB4 Receptors Forward Signaling Promotes SDF-1-induced Endothelial Cell Chemotaxis and Branching Remodeling Blood. Nov, 2006 | Pubmed ID: 16840724 G-CSF Down-regulation of CXCR4 Expression Identified As a Mechanism for Mobilization of Myeloid Cells Blood. Aug, 2006 | Pubmed ID: 16537807 Activity of Subcutaneous Interleukin-12 in AIDS-related Kaposi Sarcoma Blood. Jun, 2006 | Pubmed ID: 16507779 Ligand-induced Internalization Selects Use of Common Receptor Neuropilin-1 by VEGF165 and Semaphorin3A Blood. May, 2006 | Pubmed ID: 16424390 Up-regulation of the Notch Ligand Delta-like 4 Inhibits VEGF-induced Endothelial Cell Function Blood. Feb, 2006 | Pubmed ID: 16219802 Therapy Insight: AIDS-related Malignancies--the Influence of Antiviral Therapy on Pathogenesis and Management Nature Clinical Practice. Oncology. Aug, 2005 | Pubmed ID: 16130937 B-cell Recovery Following Rituximab-based Therapy is Associated with Perturbations in Stromal Derived Factor-1 and Granulocyte Homeostasis Blood. Aug, 2005 | Pubmed ID: 15718416 Identification of Carboxypeptidase N As an Enzyme Responsible for C-terminal Cleavage of Stromal Cell-derived Factor-1alpha in the Circulation Blood. Jun, 2005 | Pubmed ID: 15718415 Role of Human Cripto-1 in Tumor Angiogenesis Journal of the National Cancer Institute. Jan, 2005 | Pubmed ID: 15657343 Neuropilin-1 Regulates Attachment in Human Endothelial Cells Independently of Vascular Endothelial Growth Factor Receptor-2 Blood. Mar, 2005 | Pubmed ID: 15522955 Neoplastic Conditions in the Context of HIV-1 Infection Current HIV Research. Oct, 2004 | Pubmed ID: 15544455 Therapeutic Options for Human Herpesvirus-8/Kaposi's Sarcoma-associated Herpesvirus-related Disorders Expert Review of Anti-infective Therapy. Apr, 2004 | Pubmed ID: 15482187 Derivation of Endothelial Cells from CD34- Umbilical Cord Blood Stem Cells (Dayton, Ohio). 2004 | Pubmed ID: 15153615 HIV-1 Tat Enhances Kaposi Sarcoma-associated Herpesvirus (KSHV) Infectivity Blood. Aug, 2004 | Pubmed ID: 15073028 Differential Processing of Stromal-derived Factor-1alpha and Stromal-derived Factor-1beta Explains Functional Diversity Blood. Apr, 2004 | Pubmed ID: 14525775 Insulin-like Growth Factor I Induces Migration and Invasion of Human Multiple Myeloma Cells Blood. Jan, 2004 | Pubmed ID: 14504085 Selective Expression of Stromal-derived Factor-1 in the Capillary Vascular Endothelium Plays a Role in Kaposi Sarcoma Pathogenesis Blood. Dec, 2003 | Pubmed ID: 12907452 Targeted Inhibition of Angiogenic Factors in AIDS-related Disorders Current Drug Targets. Infectious Disorders. Jun, 2003 | Pubmed ID: 12769789 Viral and Cellular Cytokines As Therapeutic Targets in AIDS-related Lymphoproliferative Disorders Current Drug Targets. Cardiovascular & Haematological Disorders. Mar, 2003 | Pubmed ID: 12769647 Pathogenesis and Manifestations of Human Herpesvirus-8-associated Disorders Seminars in Hematology. Apr, 2003 | Pubmed ID: 12704591 Inhibition of STAT3 Signaling Induces Apoptosis and Decreases Survivin Expression in Primary Effusion Lymphoma Blood. Feb, 2003 | Pubmed ID: 12393476 Anti-tumor Activities of the Angiogenesis Inhibitors Interferon-inducible Protein-10 and the Calreticulin Fragment Vasostatin Cancer Immunology, Immunotherapy : CII. Sep, 2002 | Pubmed ID: 12192535 Laminin Binding to the Calreticulin Fragment Vasostatin Regulates Endothelial Cell Function Journal of Leukocyte Biology. Jan, 2002 | Pubmed ID: 11781379 Interleukin-18, Interferon-gamma, IP-10, and Mig Expression in Epstein-Barr Virus-induced Infectious Mononucleosis and Posttransplant Lymphoproliferative Disease The American Journal of Pathology. Jul, 1999 | Pubmed ID: 10393857 Interferon-inducible Protein-10 Identified As a Mediator of Tumor Necrosis in Vivo Proceedings of the National Academy of Sciences of the United States of America. Nov, 1996 | Pubmed ID: 8943014 B Cell Differentiation and Immunoregulatory T Cell Function in Human Cord Blood Lymphocytes The Journal of Clinical Investigation. Aug, 1980 | Pubmed ID: 6249850 Многоразовая одиночная клетка для итеративного эпигеномного анализа Hidetaka Ohnuki1, David J. Venzon2, Alexei Lobanov3,4, Giovanna Tosato1 1Laboratory of Cellular Oncology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, 2Biostatistics and Data Management Section, Center for Cancer Research, National Cancer Institute, National Institutes of Health, 3CCR Collaborative Bioinformatics Resource (CCBR), Center for Cancer Research, National Cancer Institute, National Institutes of Health, 4Advanced Biomedical Computational Science, Frederick National Laboratory for Cancer Research sponsored by the National Cancer Institute JoVE 63456 Genetica
Многоразовая одиночная клетка для итеративного эпигеномного анализа Hidetaka Ohnuki1, David J. Venzon2, Alexei Lobanov3,4, Giovanna Tosato1 1Laboratory of Cellular Oncology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, 2Biostatistics and Data Management Section, Center for Cancer Research, National Cancer Institute, National Institutes of Health, 3CCR Collaborative Bioinformatics Resource (CCBR), Center for Cancer Research, National Cancer Institute, National Institutes of Health, 4Advanced Biomedical Computational Science, Frederick National Laboratory for Cancer Research sponsored by the National Cancer Institute JoVE 63456 Genetica