H. Artee Luchman Hotchkiss Brain Institute, Department of Cell Biology and Anatomy, Cumming School of Medicine University of Calgary Biography Publications Institution JoVE Articles H. Artee Luchman has not added a biography. If you are H. Artee Luchman and would like to personalize this page please email our Author Liaison for assistance. Publications Clonal Expansion and Epigenetic Reprogramming Following Deletion or Amplification of Mutant Proceedings of the National Academy of Sciences of the United States of America. 10, 2017 | Pubmed ID: 28916733 Control of Glioblastoma Tumorigenesis by Feed-forward Cytokine Signaling Nature Neuroscience. Jun, 2016 | Pubmed ID: 27110918 Comparative Genomic and Genetic Analysis of Glioblastoma-derived Brain Tumor-initiating Cells and Their Parent Tumors Neuro-oncology. Mar, 2016 | Pubmed ID: 26245525 Precursor States of Brain Tumor Initiating Cell Lines Are Predictive of Survival in Xenografts and Associated with Glioblastoma Subtypes Stem Cell Reports. Jul, 2015 | Pubmed ID: 26095605 IDH1 Mutation Induces Reprogramming of Pyruvate Metabolism Cancer Research. Aug, 2015 | Pubmed ID: 26045167 Dual MTORC1/2 Blockade Inhibits Glioblastoma Brain Tumor Initiating Cells in Vitro and in Vivo and Synergizes with Temozolomide to Increase Orthotopic Xenograft Survival Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Nov, 2014 | Pubmed ID: 25316808 Novel MSH6 Mutations in Treatment-naïve Glioblastoma and Anaplastic Oligodendroglioma Contribute to Temozolomide Resistance Independently of MGMT Promoter Methylation Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Sep, 2014 | Pubmed ID: 25078279 Prostate Epithelium-specific Deletion of the Selenocysteine TRNA Gene Trsp Leads to Early Onset Intraepithelial Neoplasia The American Journal of Pathology. Mar, 2014 | Pubmed ID: 24447801 Potent Targeting of the STAT3 Protein in Brain Cancer Stem Cells: A Promising Route for Treating Glioblastoma ACS Medicinal Chemistry Letters. Nov, 2013 | Pubmed ID: 24900612 Spontaneous Loss of Heterozygosity Leading to Homozygous R132H in a Patient-derived IDH1 Mutant Cell Line Neuro-oncology. Aug, 2013 | Pubmed ID: 23757293 On-target JAK2/STAT3 Inhibition Slows Disease Progression in Orthotopic Xenografts of Human Glioblastoma Brain Tumor Stem Cells Neuro-oncology. Feb, 2013 | Pubmed ID: 23262510 DNA Hypermethylation and 1p Loss Silence NHE-1 in Oligodendroglioma Annals of Neurology. Jun, 2012 | Pubmed ID: 22718548 An in Vivo Patient-derived Model of Endogenous IDH1-mutant Glioma Neuro-oncology. Feb, 2012 | Pubmed ID: 22166263 The Pace of Prostatic Intraepithelial Neoplasia Development is Determined by the Timing of Pten Tumor Suppressor Gene Excision PloS One. 2008 | Pubmed ID: 19081794 Temporally Controlled Prostate Epithelium-specific Gene Alterations Genesis (New York, N.Y. : 2000). Apr, 2008 | Pubmed ID: 18395839 Mgmt Deficiency Alters the in Vivo Mutational Spectrum of Tissues Exposed to the Tobacco Carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) Carcinogenesis. Apr, 2008 | Pubmed ID: 18281247 Mutational-reporter Transgenes Rescued from Mice Lacking Either Mgmt, or Both Mgmt and Msh6 Suggest That O6-alkylguanine-induced Miscoding Does Not Contribute to the Spontaneous Mutational Spectrum Oncogene. Aug, 2004 | Pubmed ID: 15208683 Elevated Mutant Frequencies and Predominance of G:C to A:T Transition Mutations in Msh6(-/-) Small Intestinal Epithelium Oncogene. Oct, 2002 | Pubmed ID: 12370835 Live-Cell Imaging Assays to Study Glioblastoma Brain Tumor Stem Cell Migration and Invasion Ian Restall1, Danielle Anne Bozek1, Charles Chesnelong1,2, Samuel Weiss1, H. Artee Luchman1 1Hotchkiss Brain Institute, Department of Cell Biology and Anatomy, Cumming School of Medicine, University of Calgary, 2Department of Developmental and Stem Cell Biology Program, Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children JoVE 58152 Ricerca sul cancro
Live-Cell Imaging Assays to Study Glioblastoma Brain Tumor Stem Cell Migration and Invasion Ian Restall1, Danielle Anne Bozek1, Charles Chesnelong1,2, Samuel Weiss1, H. Artee Luchman1 1Hotchkiss Brain Institute, Department of Cell Biology and Anatomy, Cumming School of Medicine, University of Calgary, 2Department of Developmental and Stem Cell Biology Program, Arthur and Sonia Labatt Brain Tumor Research Centre, The Hospital for Sick Children JoVE 58152 Ricerca sul cancro