James Sharpe EMBL-CRG Systems Biology Program, Centre for Genomic Regulation Catalan Institute of Research and Advanced Studies Biography Publications Institution JoVE Articles James Sharpe has not added a biography. If you are James Sharpe and would like to personalize this page please email our Author Liaison for assistance. Publications Turing Patterns in Development: What About the Horse Part? Current Opinion in Genetics & Development. Dec, 2012 | Pubmed ID: 23276682 Genetics of System Biology Current Opinion in Genetics & Development. Dec, 2012 | Pubmed ID: 23273689 A Global "imaging'' View on Systems Approaches in Immunology European Journal of Immunology. Dec, 2012 | Pubmed ID: 23255008 Hox Genes Regulate Digit Patterning by Controlling the Wavelength of a Turing-type Mechanism Science (New York, N.Y.). Dec, 2012 | Pubmed ID: 23239739 Transfecting RNA Quadruplexes Results in Few Transcriptome Perturbations RNA Biology. Dec, 2012 | Pubmed ID: 23235467 Quantitative Measurements in 3-dimensional Datasets of Mouse Lymph Nodes Resolve Organ-wide Functional Dependencies Computational and Mathematical Methods in Medicine. 2012 | Pubmed ID: 23049616 Image Formation by Linear and Nonlinear Digital Scanned Light-sheet Fluorescence Microscopy with Gaussian and Bessel Beam Profiles Biomedical Optics Express. Jul, 2012 | Pubmed ID: 22808423 Image Processing Assisted Algorithms for Optical Projection Tomography IEEE Transactions on Medical Imaging. Jan, 2012 | Pubmed ID: 21768046 Antisaccade Generation is Impaired After Parietal Lobe Lesions Annals of the New York Academy of Sciences. Sep, 2011 | Pubmed ID: 21950993 Two Ways to Use Imaging: Focusing Directly on Mechanism, or Indirectly Via Behaviour? Current Opinion in Genetics & Development. Oct, 2011 | Pubmed ID: 21945001 Optical Projection Tomography of Vertebrate Embryo Development Cold Spring Harbor Protocols. Jun, 2011 | Pubmed ID: 21632785 Preparation of Mouse Embryos for Optical Projection Tomography Imaging Cold Spring Harbor Protocols. Jun, 2011 | Pubmed ID: 21632773 Posterior Reversible Encephalopathy Syndrome Presenting As Balint Syndrome Journal of Neuro-ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society. Sep, 2011 | Pubmed ID: 21566529 N-myc Controls Proliferation, Morphogenesis, and Patterning of the Inner Ear The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2011 | Pubmed ID: 21562282 Control of Pelvic Girdle Development by Genes of the Pbx Family and Emx2 Developmental Dynamics : an Official Publication of the American Association of Anatomists. May, 2011 | Pubmed ID: 21455939 Budding Behaviors: Growth of the Limb As a Model of Morphogenesis Developmental Dynamics : an Official Publication of the American Association of Anatomists. May, 2011 | Pubmed ID: 21384474 A Computational Clonal Analysis of the Developing Mouse Limb Bud PLoS Computational Biology. 2011 | Pubmed ID: 21347315 A Landmark-free Morphometric Staging System for the Mouse Limb Bud Development (Cambridge, England). Mar, 2011 | Pubmed ID: 21307091 Ocular Torsion and Vertical Misalignment Current Opinion in Neurology. Feb, 2011 | Pubmed ID: 21150599 4D Retrospective Lineage Tracing Using SPIM for Zebrafish Organogenesis Studies Journal of Biophotonics. Jan, 2011 | Pubmed ID: 20925108 An Atlas of Gene Regulatory Networks Reveals Multiple Three-gene Mechanisms for Interpreting Morphogen Gradients Molecular Systems Biology. Nov, 2010 | Pubmed ID: 21045819 Involvement of the Human Ventrolateral Thalamus in the Control of Visually Guided Saccades Brain Stimulation. Oct, 2010 | Pubmed ID: 20965452 Mechanobiology of Embryonic Skeletal Development: Insights from Animal Models Birth Defects Research. Part C, Embryo Today : Reviews. Sep, 2010 | Pubmed ID: 20860060 The Role of Spatially Controlled Cell Proliferation in Limb Bud Morphogenesis PLoS Biology. 2010 | Pubmed ID: 20644711 Scapula Development is Governed by Genetic Interactions of Pbx1 with Its Family Members and with Emx2 Via Their Cooperative Control of Alx1 Development (Cambridge, England). Aug, 2010 | Pubmed ID: 20627960 Clonal Analysis in Mice Underlines the Importance of Rhombomeric Boundaries in Cell Movement Restriction During Hindbrain Segmentation PloS One. 2010 | Pubmed ID: 20404937 Quantification and Three-dimensional Imaging of the Insulitis-induced Destruction of Beta-cells in Murine Type 1 Diabetes Diabetes. Jul, 2010 | Pubmed ID: 20393145 Live Optical Projection Tomography Organogenesis. Oct, 2009 | Pubmed ID: 20539740 Live Optical Projection Tomography Organogenesis. Oct, 2009 | Pubmed ID: 20357969 The Cerebellar Dysplasia of Chiari II Malformation As Revealed by Eye Movements The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques. Nov, 2009 | Pubmed ID: 19960749 Genetic Background Influences Embryonic Lethality and the Occurrence of Neural Tube Defects in Men1 Null Mice: Relevance to Genetic Modifiers The Journal of Endocrinology. Oct, 2009 | Pubmed ID: 19587266 Gene Expression Analysis of Canonical Wnt Pathway Transcriptional Regulators During Early Morphogenesis of the Facial Region in the Mouse Embryo Gene Expression Patterns : GEP. Jun, 2009 | Pubmed ID: 19303461 Visual Fixation in Chiari Type II Malformation Journal of Child Neurology. Feb, 2009 | Pubmed ID: 19182152 Evidence That Fgf10 Contributes to the Skeletal and Visceral Defects of an Apert Syndrome Mouse Model Developmental Dynamics : an Official Publication of the American Association of Anatomists. Feb, 2009 | Pubmed ID: 18773495 Fluorescence Lifetime Optical Projection Tomography Journal of Biophotonics. Oct, 2008 | Pubmed ID: 19343662 High-resolution Three-dimensional Imaging of Islet-infiltrate Interactions Based on Optical Projection Tomography Assessments of the Intact Adult Mouse Pancreas Journal of Biomedical Optics. Sep-Oct, 2008 | Pubmed ID: 19021448 Neurophysiology and Neuroanatomy of Smooth Pursuit: Lesion Studies Brain and Cognition. Dec, 2008 | Pubmed ID: 19004537 The Vestibulo-ocular Reflex During Active Head Motion in Chiari II Malformation The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques. Sep, 2008 | Pubmed ID: 18973069 Ocular Motor Nerve Palsies: Implications for Diagnosis and Mechanisms of Repair Progress in Brain Research. 2008 | Pubmed ID: 18718283 Dissociated Palsy of Vertical Saccades: Loss of Voluntary and Visually Guided Saccades with Preservation of Reflexive Vestibular Quick Phases Journal of Neuro-ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society. Jun, 2008 | Pubmed ID: 18562839 In Vitro Whole-organ Imaging: 4D Quantification of Growing Mouse Limb Buds Nature Methods. Jul, 2008 | Pubmed ID: 18516047 3D Representation of Wnt and Frizzled Gene Expression Patterns in the Mouse Embryo at Embryonic Day 11.5 (Ts19) Gene Expression Patterns : GEP. May, 2008 | Pubmed ID: 18364260 Localization and Fate of Fgf10-expressing Cells in the Adult Mouse Brain Implicate Fgf10 in Control of Neurogenesis Molecular and Cellular Neurosciences. Apr, 2008 | Pubmed ID: 18329286 Adaptive Neural Mechanism for Listing's Law Revealed in Patients with Skew Deviation Caused by Brainstem or Cerebellar Lesion Investigative Ophthalmology & Visual Science. Jan, 2008 | Pubmed ID: 18172094 Square Wave Jerks in Children and Adolescents Pediatric Neurology. Jan, 2008 | Pubmed ID: 18054687 Three-dimensional Imaging of Drosophila Melanogaster PloS One. 2007 | Pubmed ID: 17786206 Cell Tracing Reveals a Dorsoventral Lineage Restriction Plane in the Mouse Limb Bud Mesenchyme Development (Cambridge, England). Oct, 2007 | Pubmed ID: 17715176 The Vestibulo-ocular Reflex During Active Head Motion in Children and Adolescents Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery. Nov, 2007 | Pubmed ID: 17710419 FishNet: an Online Database of Zebrafish Anatomy BMC Biology. 2007 | Pubmed ID: 17705855 Resolution Improvement in Emission Optical Projection Tomography Physics in Medicine and Biology. May, 2007 | Pubmed ID: 17473351 Smooth Ocular Pursuit in Chiari Type II Malformation Developmental Medicine and Child Neurology. Apr, 2007 | Pubmed ID: 17376140 Tomographic Molecular Imaging and 3D Quantification Within Adult Mouse Organs Nature Methods. Jan, 2007 | Pubmed ID: 17143281 Saccadic Adaptation in Chiari Type II Malformation The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques. Nov, 2006 | Pubmed ID: 17168162 Saccadic Adaptation in Children Journal of Child Neurology. Dec, 2006 | Pubmed ID: 17156692 Spleen Versus Pancreas: Strict Control of Organ Interrelationship Revealed by Analyses of Bapx1-/- Mice Genes & Development. Aug, 2006 | Pubmed ID: 16912273 Visualizing Plant Development and Gene Expression in Three Dimensions Using Optical Projection Tomography The Plant Cell. Sep, 2006 | Pubmed ID: 16905654 Saccade Dynamics in Peripheral Vs Central Sixth Nerve Palsies Neurology. May, 2006 | Pubmed ID: 16682672 Cerebellar Vermis Morphology in Children with Spina Bifida and Chiari Type II Malformation Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery. Apr, 2006 | Pubmed ID: 16374591 Smooth Pursuit Eye Movements in Children Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale. Feb, 2006 | Pubmed ID: 16362363 Saccades in Children Vision Research. Apr, 2006 | Pubmed ID: 16051306 Correction of Artefacts in Optical Projection Tomography Physics in Medicine and Biology. Oct, 2005 | Pubmed ID: 16177495 3D Modelling, Gene Expression Mapping and Post-mapping Image Analysis in the Developing Human Brain Brain Research Bulletin. Sep, 2005 | Pubmed ID: 16144630 Cerebellar Skew Deviation and the Torsional Vestibuloocular Reflex Neurology. Aug, 2005 | Pubmed ID: 16087906 Recovery of Peripheral Versus Central Nerves Identified by Saccadic Velocity After Abducens Neuropathy Annals of the New York Academy of Sciences. Apr, 2005 | Pubmed ID: 15826994 3 Dimensional Modelling of Early Human Brain Development Using Optical Projection Tomography BMC Neuroscience. Aug, 2004 | Pubmed ID: 15298700 Optical Projection Tomography Annual Review of Biomedical Engineering. 2004 | Pubmed ID: 15255768 Effect of Aging on Visual Shape Distortion Gerontology. May-Jun, 2004 | Pubmed ID: 15114035 Progressive Ataxia and Palatal Tremor (PAPT): Clinical and MRI Assessment with Review of Palatal Tremors Brain : a Journal of Neurology. Jun, 2004 | Pubmed ID: 15090471 Widespread Tangential Dispersion and Extensive Cell Death During Early Neurogenesis in the Mouse Neocortex Developmental Biology. Mar, 2004 | Pubmed ID: 14975720 EMAP and EMAGE: a Framework for Understanding Spatially Organized Data Neuroinformatics. 2003 | Pubmed ID: 15043218 Adaptations and Deficits in the Vestibulo-ocular Reflex After Peripheral Ocular Motor Palsies Annals of the New York Academy of Sciences. Oct, 2003 | Pubmed ID: 14662452 What's Up, Doc? Altered Perception of the Haptic, Postural, and Visual Vertical Neurology. Nov, 2003 | Pubmed ID: 14610115 Optical Projection Tomography As a New Tool for Studying Embryo Anatomy Journal of Anatomy. Feb, 2003 | Pubmed ID: 12647867 The Vestibulo-ocular Reflex in Fourth Nerve Palsy: Deficits and Adaptation Vision Research. Aug, 2002 | Pubmed ID: 12207980 Vertical Misalignment in Unilateral Sixth Nerve Palsy Ophthalmology. Jul, 2002 | Pubmed ID: 12093657 Adaptive Neural Mechanism for Listing's Law Revealed in Patients with Fourth Nerve Palsy Investigative Ophthalmology & Visual Science. Jun, 2002 | Pubmed ID: 12036981 Optical Projection Tomography As a Tool for 3D Microscopy and Gene Expression Studies Science (New York, N.Y.). Apr, 2002 | Pubmed ID: 11964482 The Vertical Vestibulo-ocular Reflex, and Visual-vestibular Interaction During Active Head Motion Annals of the New York Academy of Sciences. Apr, 2002 | Pubmed ID: 11960860 Hyperdeviation and Static Ocular Counterroll in Unilateral Abducens Nerve Palsy Annals of the New York Academy of Sciences. Apr, 2002 | Pubmed ID: 11960857 Implementation of Listing's Law in Patients with Unilateral Sixth Nerve Palsy Annals of the New York Academy of Sciences. Apr, 2002 | Pubmed ID: 11960856 Midbrain Disorders of Vertical Gaze: a Quantitative Re-evaluation Annals of the New York Academy of Sciences. Apr, 2002 | Pubmed ID: 11960800 Adaptations and Deficits in the Vestibulo-ocular Reflex After Third Nerve Palsy Archives of Ophthalmology. Mar, 2002 | Pubmed ID: 11879141 Adaptive Neural Mechanism for Listing's Law Revealed in Patients with Sixth Nerve Palsy Investigative Ophthalmology & Visual Science. Jan, 2002 | Pubmed ID: 11773020 Adaptations and Deficits in the Vestibulo-ocular Reflex After Sixth Nerve Palsy Investigative Ophthalmology & Visual Science. Jan, 2002 | Pubmed ID: 11773019 Near Infrared Optical Projection Tomography for Assessments of β-cell Mass Distribution in Diabetes Research Anna U. Eriksson*1, Christoffer Svensson*1, Andreas Hörnblad1, Abbas Cheddad1, Elena Kostromina1, Maria Eriksson1, Nils Norlin1, Antonello Pileggi2, James Sharpe3, Fredrik Georgsson4, Tomas Alanentalo1, Ulf Ahlgren1 1Umeå Centre for Molecular Medicine, Umeå University, 2Cell Transplant Center, Diabetes Research Institute, University of Miami,, 3EMBL-CRG Systems Biology Program, Centre for Genomic Regulation, Catalan Institute of Research and Advanced Studies, 4Dept. of Computing Science, Umeå University JoVE 50238 Medicina
Near Infrared Optical Projection Tomography for Assessments of β-cell Mass Distribution in Diabetes Research Anna U. Eriksson*1, Christoffer Svensson*1, Andreas Hörnblad1, Abbas Cheddad1, Elena Kostromina1, Maria Eriksson1, Nils Norlin1, Antonello Pileggi2, James Sharpe3, Fredrik Georgsson4, Tomas Alanentalo1, Ulf Ahlgren1 1Umeå Centre for Molecular Medicine, Umeå University, 2Cell Transplant Center, Diabetes Research Institute, University of Miami,, 3EMBL-CRG Systems Biology Program, Centre for Genomic Regulation, Catalan Institute of Research and Advanced Studies, 4Dept. of Computing Science, Umeå University JoVE 50238 Medicina