Janet Smith School of Biosciences University of Birmingham Biography Publications Institution JoVE Articles Janet Smith has not added a biography. If you are Janet Smith and would like to personalize this page please email our Author Liaison for assistance. Publications Targeting Phosphoinositide 3-kinase δ for Allergic Asthma Biochemical Society Transactions. Feb, 2012 | Pubmed ID: 22260698 Structure and Activity of DmmA, a Marine Haloalkane Dehalogenase Protein Science : a Publication of the Protein Society. Feb, 2012 | Pubmed ID: 22124946 A New Generation of Crystallographic Validation Tools for the Protein Data Bank Structure (London, England : 1993). Oct, 2011 | Pubmed ID: 22000512 Depression in Home Healthcare Patients: a Public Health Problem The Pennsylvania Nurse. Jun, 2011 | Pubmed ID: 21928552 A New Structural Form in the SAM/metal-dependent O‑methyltransferase Family: MycE from the Mycinamicin Biosynthetic Pathway Journal of Molecular Biology. Oct, 2011 | Pubmed ID: 21884704 Automated Sample-scanning Methods for Radiation Damage Mitigation and Diffraction-based Centering of Macromolecular Crystals Journal of Synchrotron Radiation. Sep, 2011 | Pubmed ID: 21862850 A Resource for Discovering Specific and Universal Biomarkers for Distributed Stem Cells PloS One. 2011 | Pubmed ID: 21818293 Fast Fluorescence Techniques for Crystallography Beamlines Journal of Applied Crystallography. Aug, 2011 | Pubmed ID: 21808424 Structural Basis of Multifunctionality in a Vitamin B12-processing Enzyme The Journal of Biological Chemistry. Aug, 2011 | Pubmed ID: 21697092 Heterologous Production, Purification and Characterization of Enzymatically Active Sindbis Virus Nonstructural Protein NsP1 Protein Expression and Purification. Oct, 2011 | Pubmed ID: 21693190 Structure and Function of the RedJ Protein, a Thioesterase from the Prodiginine Biosynthetic Pathway in Streptomyces Coelicolor The Journal of Biological Chemistry. Jun, 2011 | Pubmed ID: 21543318 Radiation Damage in Protein Crystals is Reduced with a Micron-sized X-ray Beam Proceedings of the National Academy of Sciences of the United States of America. Apr, 2011 | Pubmed ID: 21444772 JBluIce-EPICS Control System for Macromolecular Crystallography Acta Crystallographica. Section D, Biological Crystallography. Mar, 2011 | Pubmed ID: 21358048 Terminal Alkene Formation by the Thioesterase of Curacin A Biosynthesis: Structure of a Decarboxylating Thioesterase The Journal of Biological Chemistry. Apr, 2011 | Pubmed ID: 21357626 New Ligation-independent Cloning Vectors Compatible with a High-throughput Platform for Parallel Construct Expression Evaluation Using Baculovirus-infected Insect Cells Protein Expression and Purification. May, 2011 | Pubmed ID: 21262364 Structural Basis for Substrate Activation and Regulation by Cystathionine Beta-synthase (CBS) Domains in Cystathionine {beta}-synthase Proceedings of the National Academy of Sciences of the United States of America. Dec, 2010 | Pubmed ID: 21081698 Post-prostatectomy Incontinence: Implications for Home Health Clinicians Home Healthcare Nurse. Oct, 2010 | Pubmed ID: 20881798 Food for Thought Nursing Standard (Royal College of Nursing (Great Britain) : 1987). Aug 4-10, 2010 | Pubmed ID: 20806607 A General Scheme for Synthesis of Substrate-based Polyketide Labels for Acyl Carrier Proteins Bioorganic & Medicinal Chemistry Letters. Oct, 2010 | Pubmed ID: 20801036 Conformational Switch Triggered by Alpha-ketoglutarate in a Halogenase of Curacin A Biosynthesis Proceedings of the National Academy of Sciences of the United States of America. Aug, 2010 | Pubmed ID: 20660778 Biochemical and Structural Characterization of the Tautomycetin Thioesterase: Analysis of a Stereoselective Polyketide Hydrolase Angewandte Chemie (International Ed. in English). Aug, 2010 | Pubmed ID: 20623733 Structure of the Rift Valley Fever Virus Nucleocapsid Protein Reveals Another Architecture for RNA Encapsidation Proceedings of the National Academy of Sciences of the United States of America. Jun, 2010 | Pubmed ID: 20547879 Educate Girls About Food Nursing Standard (Royal College of Nursing (Great Britain) : 1987). Mar 17-23, 2010 | Pubmed ID: 20394117 Embryonic Skeletal Muscle Microexplant Culture and Isolation of Skeletal Muscle Stem Cells Methods in Molecular Biology (Clifton, N.J.). 2010 | Pubmed ID: 20204618 Unfair Treatment Nursing Standard (Royal College of Nursing (Great Britain) : 1987). Jan 20-26, 2010 | Pubmed ID: 20191741 Crystal Structures of Dehydratase Domains from the Curacin Polyketide Biosynthetic Pathway Structure (London, England : 1993). Jan, 2010 | Pubmed ID: 20152156 Creation and Use of a Database in Clinical and Translational Research Journal of Investigative Medicine : the Official Publication of the American Federation for Clinical Research. Mar, 2010 | Pubmed ID: 20009953 Insights into the Reactivation of Cobalamin-dependent Methionine Synthase Proceedings of the National Academy of Sciences of the United States of America. Nov, 2009 | Pubmed ID: 19846791 Polyketide Decarboxylative Chain Termination Preceded by O-sulfonation in Curacin a Biosynthesis Journal of the American Chemical Society. Nov, 2009 | Pubmed ID: 19835378 Identification of Inhibitors of Yellow Fever Virus Replication Using a Replicon-based High-throughput Assay Antimicrobial Agents and Chemotherapy. Oct, 2009 | Pubmed ID: 19651907 Arousal in Obstructive Sleep Apnoea Patients is Associated with ECG RR and QT Interval Shortening and PR Interval Lengthening Journal of Sleep Research. Jun, 2009 | Pubmed ID: 19645965 Muscular Dystrophy Begins Early in Embryonic Development Deriving from Stem Cell Loss and Disrupted Skeletal Muscle Formation Disease Models & Mechanisms. Jul-Aug, 2009 | Pubmed ID: 19535499 Insights into TRNA-dependent Amidotransferase Evolution and Catalysis from the Structure of the Aquifex Aeolicus Enzyme Journal of Molecular Biology. Aug, 2009 | Pubmed ID: 19520089 Metamorphic Enzyme Assembly in Polyketide Diversification Nature. Jun, 2009 | Pubmed ID: 19494914 The Relationship of Housing and Population Health: a 30-year Retrospective Analysis Environmental Health Perspectives. Apr, 2009 | Pubmed ID: 19440499 Synthesis of the Pyoverdin Chromophore by a Biomimetic Oxidative Cyclization Organic Letters. Apr, 2009 | Pubmed ID: 19260647 Mini-beam Collimator Enables Microcrystallography Experiments on Standard Beamlines Journal of Synchrotron Radiation. Mar, 2009 | Pubmed ID: 19240333 Structural Basis for Binding Specificity Between Subclasses of Modular Polyketide Synthase Docking Domains ACS Chemical Biology. Jan, 2009 | Pubmed ID: 19146481 Structure and Functional Analysis of RifR, the Type II Thioesterase from the Rifamycin Biosynthetic Pathway The Journal of Biological Chemistry. Feb, 2009 | Pubmed ID: 19103602 Characterization of Purified Sindbis Virus NsP4 RNA-dependent RNA Polymerase Activity in Vitro Virology. Feb, 2009 | Pubmed ID: 19036396 Mocr: a Novel Fusion Tag for Enhancing Solubility That is Compatible with Structural Biology Applications Protein Expression and Purification. Jan, 2009 | Pubmed ID: 18824232 Environmental Barriers and Supports to the Health, Function, and Participation of People with Developmental and Intellectual Disabilities: Report from the State of the Science in Aging with Developmental Disabilities Conference Disability and Health Journal. Jul, 2008 | Pubmed ID: 21122723 Proteins: Ever Larger, Stranger and More Dynamic Current Opinion in Structural Biology. Dec, 2008 | Pubmed ID: 19041238 Biochemistry. An Enzyme Assembly Line Science (New York, N.Y.). Sep, 2008 | Pubmed ID: 18772425 Fitting Farewell Nursing Standard (Royal College of Nursing (Great Britain) : 1987). Aug 13-19, 2008 | Pubmed ID: 18763547 Variability of QT Interval Duration in Obstructive Sleep Apnea: an Indicator of Disease Severity Sleep. Jul, 2008 | Pubmed ID: 18652091 Role for Conserved Residues of Sindbis Virus Nonstructural Protein 2 Methyltransferase-like Domain in Regulation of Minus-strand Synthesis and Development of Cytopathic Infection Journal of Virology. Aug, 2008 | Pubmed ID: 18495773 A 7μm Mini-beam Improves Diffraction Data from Small or Imperfect Crystals of Macromolecules Acta Crystallographica. Section D, Biological Crystallography. Apr, 2008 | Pubmed ID: 18391409 Metal Active Site Elasticity Linked to Activation of Homocysteine in Methionine Synthases Proceedings of the National Academy of Sciences of the United States of America. Mar, 2008 | Pubmed ID: 18296644 Pyr RNA Binding to the Bacillus Caldolyticus PyrR Attenuation Protein - Characterization and Regulation by Uridine and Guanosine Nucleotides The FEBS Journal. Feb, 2008 | Pubmed ID: 18190533 GNAT-like Strategy for Polyketide Chain Initiation Science (New York, N.Y.). Nov, 2007 | Pubmed ID: 17991863 Crystal Structure of the ECH2 Catalytic Domain of CurF from Lyngbya Majuscula. Insights into a Decarboxylase Involved in Polyketide Chain Beta-branching The Journal of Biological Chemistry. Dec, 2007 | Pubmed ID: 17928301 Creative Thinking Nursing Standard (Royal College of Nursing (Great Britain) : 1987). Jun 6-12, 2007 | Pubmed ID: 17569373 A Role for Insulin-like Growth Factor 2 in Specification of the Fast Skeletal Muscle Fibre BMC Developmental Biology. 2007 | Pubmed ID: 17559643 Patients Are Our Best Allies Nursing Standard (Royal College of Nursing (Great Britain) : 1987). May 16-22, 2007 | Pubmed ID: 17549973 Functional Characterization of Cis and Trans Activity of the Flavivirus NS2B-NS3 Protease The Journal of Biological Chemistry. Apr, 2007 | Pubmed ID: 17337448 Transgender Trials Nursing Standard (Royal College of Nursing (Great Britain) : 1987). Feb 7-13, 2007 | Pubmed ID: 17319576 Clearing the Skies over Modular Polyketide Synthases ACS Chemical Biology. Sep, 2006 | Pubmed ID: 17168537 Preparing Data for Analysis Using Microsoft Excel Journal of Investigative Medicine : the Official Publication of the American Federation for Clinical Research. Sep, 2006 | Pubmed ID: 17134617 Preliminary Results of Sacral Neuromodulation in 23 Children The Journal of Urology. Nov, 2006 | Pubmed ID: 17070300 Catalytic Core of Alphavirus Nonstructural Protein NsP4 Possesses Terminal Adenylyltransferase Activity Journal of Virology. Oct, 2006 | Pubmed ID: 17005674 Structural and Mechanistic Insights into Polyketide Macrolactonization from Polyketide-based Affinity Labels Nature Chemical Biology. Oct, 2006 | Pubmed ID: 16969373 Structural Basis for Macrolactonization by the Pikromycin Thioesterase Nature Chemical Biology. Oct, 2006 | Pubmed ID: 16969372 Fear of Reprisals Keeps Us Quiet Nursing Standard (Royal College of Nursing (Great Britain) : 1987). Jul 26-Aug 1, 2006 | Pubmed ID: 16898194 At a Crossroad: Standing Still and Moving Forward American Journal of Community Psychology. Sep, 2006 | Pubmed ID: 16832607 Transmembrane Traffic in the Cytochrome B6f Complex Annual Review of Biochemistry. 2006 | Pubmed ID: 16756511 Stunted Growth Nursing Standard (Royal College of Nursing (Great Britain) : 1987). Apr 19-25, 2006 | Pubmed ID: 16673996 The Dictyostelium Kinome--analysis of the Protein Kinases from a Simple Model Organism PLoS Genetics. Mar, 2006 | Pubmed ID: 16596165 Increased Medial Thalamic Creatine-phosphocreatine Found by Proton Magnetic Resonance Spectroscopy in Children with Obsessive-compulsive Disorder Versus Major Depression and Healthy Controls Journal of Child Neurology. Feb, 2006 | Pubmed ID: 16566872 Myosin Light Chain Kinase A is Activated by CGMP-dependent and CGMP-independent Pathways FEBS Letters. Apr, 2006 | Pubmed ID: 16546177 Characterisation of Serum-induced Intracellular Ca2+ Oscillations in Primary Bone Marrow Stromal Cells Journal of Cellular Physiology. Mar, 2006 | Pubmed ID: 16245308 Healthcare Librarians and Learner Support: a Review of Competences and Methods Health Information and Libraries Journal. Dec, 2005 | Pubmed ID: 16279975 Reduced Anterior Cingulate Glutamate in Pediatric Major Depression: a Magnetic Resonance Spectroscopy Study Biological Psychiatry. Nov, 2005 | Pubmed ID: 16084860 Structure of the Flavivirus Helicase: Implications for Catalytic Activity, Protein Interactions, and Proteolytic Processing Journal of Virology. Aug, 2005 | Pubmed ID: 16051820 The Apo and Ternary Complex Structures of a Chemotherapeutic Target: Human Glycinamide Ribonucleotide Transformylase Biochemistry. Jul, 2005 | Pubmed ID: 16026156 Structure of the Cytochrome B6f Complex: New Prosthetic Groups, Q-space, and the 'hors D'oeuvres Hypothesis' for Assembly of the Complex Photosynthesis Research. 2005 | Pubmed ID: 15977064 Identification of Potent and Selective RNA Antagonists of the IFN-gamma-inducible CXCL10 Chemokine Biochemistry. Jun, 2005 | Pubmed ID: 15938634 A New Arrangement of (beta/alpha)8 Barrels in the Synthase Subunit of PLP Synthase The Journal of Biological Chemistry. Jul, 2005 | Pubmed ID: 15911615 Structure of the Nucleotide Complex of PyrR, the Pyr Attenuation Protein from Bacillus Caldolyticus, Suggests Dual Regulation by Pyrimidine and Purine Nucleotides Journal of Bacteriology. Mar, 2005 | Pubmed ID: 15716449 Are Natural and Unnatural Appetites Equally Controllable? A Response to Jensen's "Is Continence Enough?" Christian Bioethics. 2004 | Pubmed ID: 15764095 A Wake-up Call Nursing Standard (Royal College of Nursing (Great Britain) : 1987). Nov 24-30, 2004 | Pubmed ID: 15615169 Role of Troponin I in Active Infective Endocarditis The American Journal of Cardiology. Nov, 2004 | Pubmed ID: 15518623 Design, Expression, and Purification of a Flaviviridae Polymerase Using a High-throughput Approach to Facilitate Crystal Structure Determination Protein Science : a Publication of the Protein Society. Oct, 2004 | Pubmed ID: 15388860 Characterization of Perivascular Poly(lactic-co-glycolic Acid) Films Containing Paclitaxel International Journal of Pharmaceutics. Sep, 2004 | Pubmed ID: 15363506 Reduced Anterior Cingulate Glutamatergic Concentrations in Childhood OCD and Major Depression Versus Healthy Controls Journal of the American Academy of Child and Adolescent Psychiatry. Sep, 2004 | Pubmed ID: 15322418 Cytochrome Bc Complexes: a Common Core of Structure and Function Surrounded by Diversity in the Outlying Provinces Current Opinion in Structural Biology. Aug, 2004 | Pubmed ID: 15313237 [Structure and Function of the Cytochrome B6f Complex of Oxygenic Photosynthesis] Tanpakushitsu Kakusan Koso. Protein, Nucleic Acid, Enzyme. Jul, 2004 | Pubmed ID: 15242052 Evolution of Photosynthesis: Time-independent Structure of the Cytochrome B6f Complex Biochemistry. May, 2004 | Pubmed ID: 15147175 The Structure of the RNA-dependent RNA Polymerase from Bovine Viral Diarrhea Virus Establishes the Role of GTP in De Novo Initiation Proceedings of the National Academy of Sciences of the United States of America. Mar, 2004 | Pubmed ID: 15070734 Hypoxia Suppresses Symptom Perception in Asthma American Journal of Respiratory and Critical Care Medicine. Jun, 2004 | Pubmed ID: 15020291 Crystal Structure of Imidazole Glycerol-phosphate Dehydratase: Duplication of an Unusual Fold The Journal of Biological Chemistry. Apr, 2004 | Pubmed ID: 14724278 Regulatory Mechanism of Dictyostelium Myosin Light Chain Kinase A The Journal of Biological Chemistry. Jan, 2004 | Pubmed ID: 14570871 Site-specific Cleavage of RNA and DNA by Complementary DNA--bleomycin A5 Conjugates Bioconjugate Chemistry. Nov-Dec, 2003 | Pubmed ID: 14624648 Structure of the Cytochrome B6f Complex of Oxygenic Photosynthesis: Tuning the Cavity Science (New York, N.Y.). Nov, 2003 | Pubmed ID: 14526088 Functional Dissection of the Bacillus Subtilis Pur Operator Site Journal of Bacteriology. Jul, 2003 | Pubmed ID: 12837784 The Purine Repressor of Bacillus Subtilis: a Novel Combination of Domains Adapted for Transcription Regulation Journal of Bacteriology. Jul, 2003 | Pubmed ID: 12837783 The Relationship Between Depression and Smoking in Adolescents Adolescence. 2003 | Pubmed ID: 12803454 Substrate-induced Changes in the Ammonia Channel for Imidazole Glycerol Phosphate Synthase Biochemistry. Jun, 2003 | Pubmed ID: 12795596 Toward Understanding the Mechanism of the Complex Cyclization Reaction Catalyzed by Imidazole Glycerolphosphate Synthase: Crystal Structures of a Ternary Complex and the Free Enzyme Biochemistry. Jun, 2003 | Pubmed ID: 12795595 A Defined Protein-detergent-lipid Complex for Crystallization of Integral Membrane Proteins: The Cytochrome B6f Complex of Oxygenic Photosynthesis Proceedings of the National Academy of Sciences of the United States of America. Apr, 2003 | Pubmed ID: 12702760 CGMP Signalling: Different Ways to Create a Pathway Trends in Genetics : TIG. Mar, 2003 | Pubmed ID: 12615006 Differential Functional Properties of Calmodulin-dependent Protein Kinase IIgamma Variants Isolated from Smooth Muscle The Biochemical Journal. Jun, 2003 | Pubmed ID: 12603201 The Structure of DNA Within Cationic Lipid/DNA Complexes Biophysical Journal. Feb, 2003 | Pubmed ID: 12547792 Signaling Pathways Regulating Dictyostelium Myosin II Journal of Muscle Research and Cell Motility. 2002 | Pubmed ID: 12952069 I Knit You in Your Mother's Womb Christian Bioethics. Aug, 2002 | Pubmed ID: 12678034 Dictyostelium Discoideum Has a Single Diacylglycerol Kinase Gene with Similarity to Mammalian Theta Isoforms The Biochemical Journal. Dec, 2002 | Pubmed ID: 12296770 A Novel CGMP Signalling Pathway Mediating Myosin Phosphorylation and Chemotaxis in Dictyostelium The EMBO Journal. Sep, 2002 | Pubmed ID: 12198158 Identification of Four Candidate CGMP Targets in Dictyostelium Proceedings of the National Academy of Sciences of the United States of America. May, 2002 | Pubmed ID: 12011437 A Biologist's Guide to Synchrotron Facilities: the BioSync Web Resource Trends in Biochemical Sciences. Apr, 2002 | Pubmed ID: 11943550 Differential Scanning Calorimetric Studies of the Thermal Stability of Plasmid DNA Complexed with Cationic Lipids and Polymers Journal of Pharmaceutical Sciences. Feb, 2002 | Pubmed ID: 11835205 Contraception: a Symposium First Things (New York, N.Y.). Dec, 1998 | Pubmed ID: 11660609 Sterilizations Reconsidered? Christian Bioethics. Apr, 1998 | Pubmed ID: 11657267 Collaborative Research Involving Human Subjects: a Survey of Researchers Using International Single Project Assurances IRB. Jan-Feb, 1997 | Pubmed ID: 11654738 Abortion and Moral Development Theory: Listening with Different Ears International Philosophical Quarterly : IPQ. Mar, 1988 | Pubmed ID: 11655905 Isolation and Properties of a Regulatory Mutant in the Hexose Phosphate Transport System of Escherichia Coli FEBS Letters. Mar, 1971 | Pubmed ID: 11945650 الكبار والعضلات والهيكل العظمي الجنينية Microexplant الثقافة وعزل خلايا جذعية عضلية هيكلية Deborah Merrick1, Hung-Chih Chen1, Dean Larner1, Janet Smith1 1School of Biosciences, University of Birmingham JoVE 2051 Biologia
الكبار والعضلات والهيكل العظمي الجنينية Microexplant الثقافة وعزل خلايا جذعية عضلية هيكلية Deborah Merrick1, Hung-Chih Chen1, Dean Larner1, Janet Smith1 1School of Biosciences, University of Birmingham JoVE 2051 Biologia