Jason A. Burdick Department of Bioengineering, School of Engineering and Applied Sciences University of Pennsylvania Biography Publications Institution JoVE Articles Jason A. Burdick has not added a biography. If you are Jason A. Burdick and would like to personalize this page please email our Author Liaison for assistance. Publications Microstructured Hydrogels to Guide Self-assembly and Function of Lung Alveolospheres Advanced Materials (Deerfield Beach, Fla.). May, 2022 | Pubmed ID: 35522531 Simultaneous One-pot Interpenetrating Network Formation to Expand 3D Processing Capabilities Advanced Materials (Deerfield Beach, Fla.). May, 2022 | Pubmed ID: 35510317 Programming Hydrogels to Probe Spatiotemporal Cell Biology Cell Stem Cell. May, 2022 | Pubmed ID: 35413278 Methods to Characterize Granular Hydrogel Rheological Properties, Porosity, and Cell Invasion ACS Biomaterials Science & Engineering. Apr, 2022 | Pubmed ID: 35330993 Sticking Together: Injectable Granular Hydrogels with Increased Functionality Via Dynamic Covalent Inter-Particle Crosslinking Small (Weinheim an Der Bergstrasse, Germany). Mar, 2022 | Pubmed ID: 35315233 Metabolic Labeling of Secreted Matrix to Investigate Cell-material Interactions in Tissue Engineering and Mechanobiology Nature Protocols. 03, 2022 | Pubmed ID: 35140408 Harnessing Tissue-derived Extracellular Vesicles for Osteoarthritis Theranostics Theranostics. 2022 | Pubmed ID: 34987642 Anisotropic Rod-Shaped Particles Influence Injectable Granular Hydrogel Properties and Cell Invasion Advanced Materials (Deerfield Beach, Fla.). Mar, 2022 | Pubmed ID: 34932833 Computational Modeling and Experimental Characterization of Extrusion Printing into Suspension Baths Advanced Healthcare Materials. Apr, 2022 | Pubmed ID: 34699689 Fabrication of MSC-laden Composites of Hyaluronic Acid Hydrogels Reinforced with MEW Scaffolds for Cartilage Repair Biofabrication. 12, 2021 | Pubmed ID: 34788748 Programmable and Contractile Materials Through Cell Encapsulation in Fibrous Hydrogel Assemblies Science Advances. Nov, 2021 | Pubmed ID: 34757787 Introduction: Polymeric Biomaterials Chemical Reviews. 09, 2021 | Pubmed ID: 34547892 Editorial: Special Issue on Advanced Biomedical Hydrogels ACS Biomaterials Science & Engineering. 09, 2021 | Pubmed ID: 34510909 A Biofabrication Method to Align Cells Within Bioprinted Photocrosslinkable and Cell-degradable Hydrogel Constructs Via Embedded Fibers Biofabrication. 09, 2021 | Pubmed ID: 34507304 Restoring Lost Nigrostriatal Fibers in Parkinson's Disease Based on Clinically-inspired Design Criteria Brain Research Bulletin. 10, 2021 | Pubmed ID: 34332016 Novel Treatment for Glioblastoma Delivered by a Radiation Responsive and Radiopaque Hydrogel ACS Biomaterials Science & Engineering. 07, 2021 | Pubmed ID: 34160196 Enhanced Mechanosensing of Cells in Synthetic 3D Matrix with Controlled Biophysical Dynamics Nature Communications. 06, 2021 | Pubmed ID: 34112772 Emerging Technologies Provide Insights on Cancer Extracellular Matrix Biology and Therapeutics IScience. May, 2021 | Pubmed ID: 34027324 Detecting and Monitoring Hydrogels with Medical Imaging ACS Biomaterials Science & Engineering. 09, 2021 | Pubmed ID: 33979137 Nanofibrous Hyaluronic Acid Scaffolds Delivering TGF-β3 and SDF-1α for Articular Cartilage Repair in a Large Animal Model Acta Biomaterialia. 05, 2021 | Pubmed ID: 33753316 Stabilization of Damaged Articular Cartilage with Hydrogel-Mediated Reinforcement and Sealing Advanced Healthcare Materials. 05, 2021 | Pubmed ID: 33738988 Therapeutic Efficacy of Cryopreserved, Allogeneic Extracellular Vesicles for Treatment of Acute Myocardial Infarction International Heart Journal. Mar, 2021 | Pubmed ID: 33731514 Genomic, Epigenomic, and Biophysical Cues Controlling the Emergence of the Lung Alveolus Science (New York, N.Y.). 03, 2021 | Pubmed ID: 33707239 Influence of Microgel Fabrication Technique on Granular Hydrogel Properties ACS Biomaterials Science & Engineering. 09, 2021 | Pubmed ID: 33591726 Nuclear Envelope Wrinkling Predicts Mesenchymal Progenitor Cell Mechano-response in 2D and 3D Microenvironments Biomaterials. 03, 2021 | Pubmed ID: 33540172 3D Bioprinting of High Cell-density Heterogeneous Tissue Models Through Spheroid Fusion Within Self-healing Hydrogels Nature Communications. 02, 2021 | Pubmed ID: 33531489 Bioprinting for the Biologist Cell. 01, 2021 | Pubmed ID: 33417859 Chemically Modified Biopolymers for the Formation of Biomedical Hydrogels Chemical Reviews. 09, 2021 | Pubmed ID: 33356174 Injectable Hyaluronic Acid and Platelet Lysate-derived Granular Hydrogels for Biomedical Applications Acta Biomaterialia. 01, 2021 | Pubmed ID: 33130309 Resorbable Pins to Enhance Scaffold Retention in a Porcine Chondral Defect Model Cartilage. 12, 2021 | Pubmed ID: 33034511 Enhancing Biopolymer Hydrogel Functionality Through Interpenetrating Networks Trends in Biotechnology. 05, 2021 | Pubmed ID: 32950262 Metabolic Labeling to Probe the Spatiotemporal Accumulation of Matrix at the Chondrocyte-Hydrogel Interface Advanced Functional Materials. Oct, 2020 | Pubmed ID: 34211359 Hydrogel Microparticles for Biomedical Applications Nature Reviews. Materials. Jan, 2020 | Pubmed ID: 34123409 A Bioengineered Neuregulin-Hydrogel Therapy Reduces Scar Size and Enhances Post-Infarct Ventricular Contractility in an Ovine Large Animal Model Journal of Cardiovascular Development and Disease. Nov, 2020 | Pubmed ID: 33212844 Engineered Full-Length Fibronectin-Hyaluronic Acid Hydrogels for Stem Cell Engineering Advanced Healthcare Materials. 11, 2020 | Pubmed ID: 33002348 Expanding and Optimizing 3D Bioprinting Capabilities Using Complementary Network Bioinks Science Advances. 09, 2020 | Pubmed ID: 32948593 How Hydrogel Inclusions Modulate the Local Mechanical Response in Early and Fully Formed Post-infarcted Myocardium Acta Biomaterialia. 09, 2020 | Pubmed ID: 32739434 Nuclear Softening Expedites Interstitial Cell Migration in Fibrous Networks and Dense Connective Tissues Science Advances. 06, 2020 | Pubmed ID: 32596438 Imaging of Injectable Hydrogels Delivered into Myocardium with SPECT/CT Advanced Healthcare Materials. 07, 2020 | Pubmed ID: 32543053 Special Issue: Biomaterials in Mechanobiology Advanced Healthcare Materials. 04, 2020 | Pubmed ID: 32495494 Fundamentals and Applications of Photo-Cross-Linking in Bioprinting Chemical Reviews. 10, 2020 | Pubmed ID: 32302091 Engineered Biomaterial Platforms to Study Fibrosis Advanced Healthcare Materials. 04, 2020 | Pubmed ID: 32181987 Influence of Fiber Stiffness on Meniscal Cell Migration into Dense Fibrous Networks Advanced Healthcare Materials. 04, 2020 | Pubmed ID: 31867881 Mechanochemical Adhesion and Plasticity in Multifiber Hydrogel Networks Advanced Materials (Deerfield Beach, Fla.). Feb, 2020 | Pubmed ID: 31851400 Injectable Shear-Thinning Hydrogels Prevent Ischemic Mitral Regurgitation and Normalize Ventricular Flow Dynamics Seminars in Thoracic and Cardiovascular Surgery. Autumn, 2020 | Pubmed ID: 31682905 Recent Advances in Enabling Technologies in 3D Printing for Precision Medicine Advanced Materials (Deerfield Beach, Fla.). Apr, 2020 | Pubmed ID: 31512289 Delayed Delivery of Endothelial Progenitor Cell-derived Extracellular Vesicles Via Shear Thinning Gel Improves Postinfarct Hemodynamics The Journal of Thoracic and Cardiovascular Surgery. 05, 2020 | Pubmed ID: 31353103 Engineered Fibrous Networks To Investigate the Influence of Fiber Mechanics on Myofibroblast Differentiation ACS Biomaterials Science & Engineering. Aug, 2019 | Pubmed ID: 33438429 Tailoring Supramolecular Guest-host Hydrogel Viscoelasticity with Covalent Fibrinogen Double Networks Journal of Materials Chemistry. B. 03, 2019 | Pubmed ID: 32254917 3D Bioprinting Via an in Situ Crosslinking Technique Towards Engineering Cartilage Tissue Scientific Reports. 12, 2019 | Pubmed ID: 31882612 Injectable and Conductive Granular Hydrogels for 3D Printing and Electroactive Tissue Support Advanced Science (Weinheim, Baden-Wurttemberg, Germany). Oct, 2019 | Pubmed ID: 31637164 Influence of Hyaluronic Acid Modification on CD44 Binding Towards the Design of Hydrogel Biomaterials Biomaterials. 11, 2019 | Pubmed ID: 31480001 Moving Hydrogels to the Fourth Dimension Nature Materials. 09, 2019 | Pubmed ID: 31435068 Local Nascent Protein Deposition and Remodelling Guide Mesenchymal Stromal Cell Mechanosensing and Fate in Three-dimensional Hydrogels Nature Materials. 08, 2019 | Pubmed ID: 30886401 Bioactive Factors for Cartilage Repair and Regeneration: Improving Delivery, Retention, and Activity Acta Biomaterialia. 07, 2019 | Pubmed ID: 30711660 Extracellular Vesicles Mediate Improved Functional Outcomes in Engineered Cartilage Produced from MSC/chondrocyte Cocultures Proceedings of the National Academy of Sciences of the United States of America. 01, 2019 | Pubmed ID: 30647113 Jammed Microgel Inks for 3D Printing Applications Advanced Science (Weinheim, Baden-Wurttemberg, Germany). Jan, 2019 | Pubmed ID: 30643716 Delivery of Progenitor Cells with Injectable Shear-thinning Hydrogel Maintains Geometry and Normalizes Strain to Stabilize Cardiac Function After Ischemia The Journal of Thoracic and Cardiovascular Surgery. 04, 2019 | Pubmed ID: 30579534 Gallol-derived ECM-mimetic Adhesive Bioinks Exhibiting Temporal Shear-thinning and Stabilization Behavior Acta Biomaterialia. 09, 2019 | Pubmed ID: 30366132 Injectable Supramolecular Hydrogel/Microgel Composites for Therapeutic Delivery Macromolecular Bioscience. 01, 2019 | Pubmed ID: 30259658 Biofabrication Strategies for 3D in Vitro Models and Regenerative Medicine Nature Reviews. Materials. May, 2018 | Pubmed ID: 31223488 Injectable and Protease-degradable Hydrogel for SiRNA Sequestration and Triggered Delivery to the Heart Journal of Controlled Release : Official Journal of the Controlled Release Society. 09, 2018 | Pubmed ID: 29981357 Delivery of a Matrix Metalloproteinase-responsive Hydrogel Releasing TIMP-3 After Myocardial Infarction: Effects on Left Ventricular Remodeling American Journal of Physiology. Heart and Circulatory Physiology. 10, 2018 | Pubmed ID: 29979624 Cathelicidin Related Antimicrobial Peptide (CRAMP) Enhances Bone Marrow Cell Retention and Attenuates Cardiac Dysfunction in a Mouse Model of Myocardial Infarction Stem Cell Reviews and Reports. Oct, 2018 | Pubmed ID: 29948752 Effects of Hydrogel Injection on Borderzone Contractility Post-myocardial Infarction Biomechanics and Modeling in Mechanobiology. Oct, 2018 | Pubmed ID: 29855734 Nuclear-Import Receptors Reverse Aberrant Phase Transitions of RNA-Binding Proteins with Prion-like Domains Cell. 04, 2018 | Pubmed ID: 29677512 Injectable Granular Hydrogels with Multifunctional Properties for Biomedical Applications Advanced Materials (Deerfield Beach, Fla.). May, 2018 | Pubmed ID: 29602270 Facile Biofabrication of Heterogeneous Multilayer Tubular Hydrogels by Fast Diffusion-Induced Gelation ACS Applied Materials & Interfaces. Apr, 2018 | Pubmed ID: 29582989 Sustained Release of Endothelial Progenitor Cell-derived Extracellular Vesicles from Shear-thinning Hydrogels Improves Angiogenesis and Promotes Function After Myocardial Infarction Cardiovascular Research. 06, 2018 | Pubmed ID: 29566124 Matching Material and Cellular Timescales Maximizes Cell Spreading on Viscoelastic Substrates Proceedings of the National Academy of Sciences of the United States of America. 03, 2018 | Pubmed ID: 29507238 Antisecretory Factor-Mediated Inhibition of Cell Volume Dynamics Produces Antitumor Activity in Glioblastoma Molecular Cancer Research : MCR. 05, 2018 | Pubmed ID: 29431617 Engineering Stem and Stromal Cell Therapies for Musculoskeletal Tissue Repair Cell Stem Cell. 03, 2018 | Pubmed ID: 29429944 Combinatorial Hydrogels with Biochemical Gradients for Screening 3D Cellular Microenvironments Nature Communications. 02, 2018 | Pubmed ID: 29426836 Reversible Control of Network Properties in Azobenzene-Containing Hyaluronic Acid-Based Hydrogels Bioconjugate Chemistry. 04, 2018 | Pubmed ID: 29406696 Dose and Timing of N-Cadherin Mimetic Peptides Regulate MSC Chondrogenesis Within Hydrogels Advanced Healthcare Materials. 05, 2018 | Pubmed ID: 29359863 Three-dimensional Extrusion Bioprinting of Single- and Double-network Hydrogels Containing Dynamic Covalent Crosslinks Journal of Biomedical Materials Research. Part A. 04, 2018 | Pubmed ID: 29314616 Ruthenium-Crosslinked Hydrogels with Rapid, Visible-Light Degradation Chemistry (Weinheim an Der Bergstrasse, Germany). Feb, 2018 | Pubmed ID: 29161461 Biofabrication: A Guide to Technology and Terminology Trends in Biotechnology. 04, 2018 | Pubmed ID: 29137814 Photopatterned Hydrogels to Investigate the Endothelial Cell Response to Matrix Stiffness Heterogeneity ACS Biomaterials Science & Engineering. Nov, 2017 | Pubmed ID: 33418721 Local and Sustained MiRNA Delivery from an Injectable Hydrogel Promotes Cardiomyocyte Proliferation and Functional Regeneration After Ischemic Injury Nature Biomedical Engineering. 2017 | Pubmed ID: 29354322 Methods To Assess Shear-Thinning Hydrogels for Application As Injectable Biomaterials ACS Biomaterials Science & Engineering. Dec, 2017 | Pubmed ID: 29250593 Programmed Biomolecule Delivery to Enable and Direct Cell Migration for Connective Tissue Repair Nature Communications. 11, 2017 | Pubmed ID: 29176654 Computational Sensitivity Investigation of Hydrogel Injection Characteristics for Myocardial Support Journal of Biomechanics. 11, 2017 | Pubmed ID: 28888476 Matrix Degradability Controls Multicellularity of 3D Cell Migration Nature Communications. 08, 2017 | Pubmed ID: 28851858 Mechanically Dynamic PDMS Substrates to Investigate Changing Cell Environments Biomaterials. Nov, 2017 | Pubmed ID: 28843064 Hydrogels with Reversible Mechanics to Probe Dynamic Cell Microenvironments Angewandte Chemie (International Ed. in English). 09, 2017 | Pubmed ID: 28799225 Shear-thinning and Self-healing Hydrogels As Injectable Therapeutics and for 3D-printing Nature Protocols. Aug, 2017 | Pubmed ID: 28683063 Enhanced Nutrient Transport Improves the Depth-dependent Properties of Tri-layered Engineered Cartilage Constructs with Zonal Co-culture of Chondrocytes and MSCs Acta Biomaterialia. 08, 2017 | Pubmed ID: 28629894 Multiscale Model Predicts Increasing Focal Adhesion Size with Decreasing Stiffness in Fibrous Matrices Proceedings of the National Academy of Sciences of the United States of America. 06, 2017 | Pubmed ID: 28468803 Thermosensitive Poly(N-vinylcaprolactam) Injectable Hydrogels for Cartilage Tissue Engineering Tissue Engineering. Part A. 09, 2017 | Pubmed ID: 28384053 Epicardial YAP/TAZ Orchestrate an Immunosuppressive Response Following Myocardial Infarction The Journal of Clinical Investigation. Mar, 2017 | Pubmed ID: 28165342 Recent Advances in Hydrogels for Cartilage Tissue Engineering European Cells & Materials. 01, 2017 | Pubmed ID: 28138955 Injectable, Guest-Host Assembled Polyethylenimine Hydrogel for SiRNA Delivery Biomacromolecules. 01, 2017 | Pubmed ID: 27997133 A Generalizable Strategy for the 3D Bioprinting of Hydrogels from Nonviscous Photo-crosslinkable Inks Advanced Materials (Deerfield Beach, Fla.). Feb, 2017 | Pubmed ID: 27982464 Engineered Hydrogels for Local and Sustained Delivery of RNA-Interference Therapies Advanced Healthcare Materials. Jan, 2017 | Pubmed ID: 27976524 3D Printing of Shear-Thinning Hyaluronic Acid Hydrogels with Secondary Cross-Linking ACS Biomaterials Science & Engineering. Oct, 2016 | Pubmed ID: 33440472 Editorial: Special Issue on 3D Printing of Biomaterials ACS Biomaterials Science & Engineering. Oct, 2016 | Pubmed ID: 33440467 Injectable Shear-Thinning Hydrogels for Minimally Invasive Delivery to Infarcted Myocardium to Limit Left Ventricular Remodeling Circulation. Cardiovascular Interventions. 10, 2016 | Pubmed ID: 27729419 3D Printing of Photocurable Poly(glycerol Sebacate) Elastomers Biofabrication. 10, 2016 | Pubmed ID: 27716633 Evolution of Hierarchical Porous Structures in Supramolecular Guest-host Hydrogels Soft Matter. Sep, 2016 | Pubmed ID: 27714343 Computational Investigation of Transmural Differences in Left Ventricular Contractility Journal of Biomechanical Engineering. 11, 2016 | Pubmed ID: 27591094 N-cadherin Adhesive Interactions Modulate Matrix Mechanosensing and Fate Commitment of Mesenchymal Stem Cells Nature Materials. Aug, 2016 | Pubmed ID: 27525568 Injectable and Cytocompatible Tough Double-Network Hydrogels Through Tandem Supramolecular and Covalent Crosslinking Advanced Materials (Deerfield Beach, Fla.). Oct, 2016 | Pubmed ID: 27479881 Dimensionality and Spreading Influence MSC YAP/TAZ Signaling in Hydrogel Environments Biomaterials. 10, 2016 | Pubmed ID: 27429252 Near-infrared Light Triggered Release of Molecules from Supramolecular Hydrogel-nanorod Composites Nanomedicine (London, England). 06, 2016 | Pubmed ID: 27176049 Gradually Softening Hydrogels for Modeling Hepatic Stellate Cell Behavior During Fibrosis Regression Integrative Biology : Quantitative Biosciences from Nano to Macro. 06, 2016 | Pubmed ID: 27162057 Effects of Using the Unloaded Configuration in Predicting the in Vivo Diastolic Properties of the Heart Computer Methods in Biomechanics and Biomedical Engineering. Dec, 2016 | Pubmed ID: 27153460 A Practical Guide to Hydrogels for Cell Culture Nature Methods. 04, 2016 | Pubmed ID: 27123816 Single Cell Imaging to Probe Mesenchymal Stem Cell N-Cadherin Mediated Signaling Within Hydrogels Annals of Biomedical Engineering. 06, 2016 | Pubmed ID: 27106637 Effects of Mesenchymal Stem Cell and Growth Factor Delivery on Cartilage Repair in a Mini-Pig Model Cartilage. Apr, 2016 | Pubmed ID: 27047640 Delivery of Interleukin-10 Via Injectable Hydrogels Improves Renal Outcomes and Reduces Systemic Inflammation Following Ischemic Acute Kidney Injury in Mice American Journal of Physiology. Renal Physiology. 08, 2016 | Pubmed ID: 26962109 Recent Advances in Hyaluronic Acid Hydrogels for Biomedical Applications Current Opinion in Biotechnology. 08, 2016 | Pubmed ID: 26930175 Stiffening Hydrogels for Investigating the Dynamics of Hepatic Stellate Cell Mechanotransduction During Myofibroblast Activation Scientific Reports. Feb, 2016 | Pubmed ID: 26906177 To Serve and Protect: Hydrogels to Improve Stem Cell-Based Therapies Cell Stem Cell. Jan, 2016 | Pubmed ID: 26748751 Computational Modeling of Healthy Myocardium in Diastole Annals of Biomedical Engineering. Apr, 2016 | Pubmed ID: 26215308 Selective Proteolytic Degradation of Guest-Host Assembled, Injectable Hyaluronic Acid Hydrogels ACS Biomaterials Science & Engineering. Apr, 2015 | Pubmed ID: 33435051 Visualization of Injectable Hydrogels Using Chemical Exchange Saturation Transfer MRI ACS Biomaterials Science & Engineering. Apr, 2015 | Pubmed ID: 33435047 Sustained Small Molecule Delivery from Injectable Hyaluronic Acid Hydrogels Through Host-Guest Mediated Retention Journal of Materials Chemistry. B. Oct, 2015 | Pubmed ID: 26693019 Progress in Material Design for Biomedical Applications Proceedings of the National Academy of Sciences of the United States of America. Nov, 2015 | Pubmed ID: 26598696 Shear-Thinning Supramolecular Hydrogels with Secondary Autonomous Covalent Crosslinking to Modulate Viscoelastic Properties Advanced Functional Materials. Jan, 2015 | Pubmed ID: 26526097 Regulation Policy on Tissue Engineering and Regenerative Medicine in Asian-Pacific Region Tissue Engineering. Part A. Dec, 2015 | Pubmed ID: 26486210 Cell-mediated Fibre Recruitment Drives Extracellular Matrix Mechanosensing In engineered Fibrillar Microenvironments Nature Materials. Dec, 2015 | Pubmed ID: 26461445 Supramolecular Guest-Host Interactions for the Preparation of Biomedical Materials Bioconjugate Chemistry. Dec, 2015 | Pubmed ID: 26439898 Fibrous Scaffolds with Varied Fiber Chemistry and Growth Factor Delivery Promote Repair in a Porcine Cartilage Defect Model Tissue Engineering. Part A. Nov, 2015 | Pubmed ID: 26401910 Injectable Shear-thinning Hydrogels Used to Deliver Endothelial Progenitor Cells, Enhance Cell Engraftment, and Improve Ischemic Myocardium The Journal of Thoracic and Cardiovascular Surgery. Nov, 2015 | Pubmed ID: 26293548 MRI Evaluation of Injectable Hyaluronic Acid-based Hydrogel Therapy to Limit Ventricular Remodeling After Myocardial Infarction Biomaterials. Nov, 2015 | Pubmed ID: 26280951 Author Response: New Therapies for Reducing Post-myocardial Left Ventricular Remodeling Annals of Translational Medicine. Jun, 2015 | Pubmed ID: 26207239 Direct 3D Printing of Shear-Thinning Hydrogels into Self-Healing Hydrogels Advanced Materials (Deerfield Beach, Fla.). Sep, 2015 | Pubmed ID: 26177925 One-Step Generation of Multifunctional Polyelectrolyte Microcapsules Via Nanoscale Interfacial Complexation in Emulsion (NICE) ACS Nano. Aug, 2015 | Pubmed ID: 26172934 Temporal Changes in Infarct Material Properties: An In Vivo Assessment Using Magnetic Resonance Imaging and Finite Element Simulations The Annals of Thoracic Surgery. Aug, 2015 | Pubmed ID: 26095107 Role Played by Prx1-dependent Extracellular Matrix Properties in Vascular Smooth Muscle Development in Embryonic Lungs Pulmonary Circulation. Jun, 2015 | Pubmed ID: 26064466 Synergistic Effects of SDF-1α and BMP-2 Delivery from Proteolytically Degradable Hyaluronic Acid Hydrogels for Bone Repair Macromolecular Bioscience. Sep, 2015 | Pubmed ID: 26059079 Local Immunotherapy Via Delivery of Interleukin-10 and Transforming Growth Factor β Antagonist for Treatment of Chronic Kidney Disease Journal of Controlled Release : Official Journal of the Controlled Release Society. May, 2015 | Pubmed ID: 25804871 Protease-degradable Electrospun Fibrous Hydrogels Nature Communications. Mar, 2015 | Pubmed ID: 25799370 From Repair to Regeneration: Biomaterials to Reprogram the Meniscus Wound Microenvironment Annals of Biomedical Engineering. Mar, 2015 | Pubmed ID: 25650096 Nanofibrous Hydrogels with Spatially Patterned Biochemical Signals to Control Cell Behavior Advanced Materials (Deerfield Beach, Fla.). Feb, 2015 | Pubmed ID: 25640972 Injectable Microsphere Gel Progressively Improves Global Ventricular Function, Regional Contractile Strain, and Mitral Regurgitation After Myocardial Infarction The Annals of Thoracic Surgery. Feb, 2015 | Pubmed ID: 25524397 Cartilage Repair and Subchondral Bone Remodeling in Response to Focal Lesions in a Mini-pig Model: Implications for Tissue Engineering Tissue Engineering. Part A. Feb, 2015 | Pubmed ID: 25318414 Estimating Passive Mechanical Properties in a Myocardial Infarction Using MRI and Finite Element Simulations Biomechanics and Modeling in Mechanobiology. Jun, 2015 | Pubmed ID: 25315521 Materials Science: Radicals Promote Magnetic Gel Assembly Nature. Oct, 2014 | Pubmed ID: 25355357 Targeted Injection of a Biocomposite Material Alters Macrophage and Fibroblast Phenotype and Function Following Myocardial Infarction: Relation to Left Ventricular Remodeling The Journal of Pharmacology and Experimental Therapeutics. Sep, 2014 | Pubmed ID: 25022514 Incorporation of Sulfated Hyaluronic Acid Macromers into Degradable Hydrogel Scaffolds for Sustained Molecule Delivery Biomaterials Science. 2014 | Pubmed ID: 24955239 Modulating Hydrogel Crosslink Density and Degradation to Control Bone Morphogenetic Protein Delivery and in Vivo Bone Formation Journal of Controlled Release : Official Journal of the Controlled Release Society. Oct, 2014 | Pubmed ID: 24905414 A Bioengineered Hydrogel System Enables Targeted and Sustained Intramyocardial Delivery of Neuregulin, Activating the Cardiomyocyte Cell Cycle and Enhancing Ventricular Function in a Murine Model of Ischemic Cardiomyopathy Circulation. Heart Failure. Jul, 2014 | Pubmed ID: 24902740 Hyaluronic Acid Hydrogel Stiffness and Oxygen Tension Affect Cancer Cell Fate and Endothelial Sprouting Biomaterials Science. May, 2014 | Pubmed ID: 24748963 Injectable and Bioresponsive Hydrogels for On-demand Matrix Metalloproteinase Inhibition Nature Materials. Jun, 2014 | Pubmed ID: 24681647 Local Hydrogel Release of Recombinant TIMP-3 Attenuates Adverse Left Ventricular Remodeling After Experimental Myocardial Infarction Science Translational Medicine. Feb, 2014 | Pubmed ID: 24523321 Transdermal Gelation of Methacrylated Macromers with Near-infrared Light and Gold Nanorods Nanotechnology. Jan, 2014 | Pubmed ID: 24334436 Experimental and Computational Investigation of Altered Mechanical Properties in Myocardium After Hydrogel Injection Annals of Biomedical Engineering. Jul, 2014 | Pubmed ID: 24271262 Immunotherapy with Injectable Hydrogels to Treat Obstructive Nephropathy Journal of Biomedical Materials Research. Part A. Jul, 2014 | Pubmed ID: 23913854 Jagged1 Immobilization to an Osteoconductive Polymer Activates the Notch Signaling Pathway and Induces Osteogenesis Journal of Biomedical Materials Research. Part A. May, 2014 | Pubmed ID: 23775982 Hydrogels with Differential and Patterned Mechanics to Study Stiffness-mediated Myofibroblastic Differentiation of Hepatic Stellate Cells Journal of the Mechanical Behavior of Biomedical Materials. Dec, 2013 | Pubmed ID: 24361340 Rational Design of Network Properties in Guest-host Assembled and Shear-thinning Hyaluronic Acid Hydrogels Biomacromolecules. Nov, 2013 | Pubmed ID: 24070551 Synthesis and Orthogonal Photopatterning of Hyaluronic Acid Hydrogels with Thiol-norbornene Chemistry Biomaterials. Dec, 2013 | Pubmed ID: 24060422 Sustained Release of Engineered Stromal Cell-derived Factor 1-α from Injectable Hydrogels Effectively Recruits Endothelial Progenitor Cells and Preserves Ventricular Function After Myocardial Infarction Circulation. Sep, 2013 | Pubmed ID: 24030424 Localized Targeting of Biomaterials Following Myocardial Infarction: a Foundation to Build On Trends in Cardiovascular Medicine. Nov, 2013 | Pubmed ID: 23746937 Hydrogels That Mimic Developmentally Relevant Matrix and N-cadherin Interactions Enhance MSC Chondrogenesis Proceedings of the National Academy of Sciences of the United States of America. Jun, 2013 | Pubmed ID: 23733927 Fibrous Hyaluronic Acid Hydrogels That Direct MSC Chondrogenesis Through Mechanical and Adhesive Cues Biomaterials. Jul, 2013 | Pubmed ID: 23623322 Engineering Synthetic Hydrogel Microenvironments to Instruct Stem Cells Current Opinion in Biotechnology. Oct, 2013 | Pubmed ID: 23545441 Degradation-mediated Cellular Traction Directs Stem Cell Fate in Covalently Crosslinked Three-dimensional Hydrogels Nature Materials. May, 2013 | Pubmed ID: 23524375 Integration and Regression of Implanted Engineered Human Vascular Networks During Deep Wound Healing Stem Cells Translational Medicine. Apr, 2013 | Pubmed ID: 23486832 Acellular Biomaterials: an Evolving Alternative to Cell-based Therapies Science Translational Medicine. Mar, 2013 | Pubmed ID: 23486777 Secondary Photocrosslinking of Injectable Shear-thinning Dock-and-lock Hydrogels Advanced Healthcare Materials. Jul, 2013 | Pubmed ID: 23299998 Stem Cell Response to Spatially and Temporally Displayed and Reversible Surface Topography Advanced Healthcare Materials. Jan, 2013 | Pubmed ID: 23184470 The Influence of Hyaluronic Acid Hydrogel Crosslinking Density and Macromolecular Diffusivity on Human MSC Chondrogenesis and Hypertrophy Biomaterials. Jan, 2013 | Pubmed ID: 23084553 Moving from Static to Dynamic Complexity in Hydrogel Design Nature Communications. 2012 | Pubmed ID: 23232399 Sacrificial Nanofibrous Composites Provide Instruction Without Impediment and Enable Functional Tissue Formation Proceedings of the National Academy of Sciences of the United States of America. Aug, 2012 | Pubmed ID: 22872864 Synergistic Effects of SDF-1α Chemokine and Hyaluronic Acid Release from Degradable Hydrogels on Directing Bone Marrow Derived Cell Homing to the Myocardium Biomaterials. Nov, 2012 | Pubmed ID: 22835643 Spatial Control of Cell-mediated Degradation to Regulate Vasculogenesis and Angiogenesis in Hyaluronan Hydrogels Biomaterials. Sep, 2012 | Pubmed ID: 22672833 Tunable Hydrogel-microsphere Composites That Modulate Local Inflammation and Collagen Bulking Acta Biomaterialia. Sep, 2012 | Pubmed ID: 22659176 High Mesenchymal Stem Cell Seeding Densities in Hyaluronic Acid Hydrogels Produce Engineered Cartilage with Native Tissue Properties Acta Biomaterialia. Aug, 2012 | Pubmed ID: 22546516 Stiffening Hydrogels to Probe Short- and Long-term Cellular Responses to Dynamic Mechanics Nature Communications. Apr, 2012 | Pubmed ID: 22531177 Improved Cartilage Repair Via in Vitro Pre-maturation of MSC-seeded Hyaluronic Acid Hydrogels Biomedical Materials (Bristol, England). Apr, 2012 | Pubmed ID: 22455999 Injectable Shear-thinning Hydrogels Engineered with a Self-assembling Dock-and-Lock Mechanism Biomaterials. Mar, 2012 | Pubmed ID: 22177842 Ischemia Induces P-selectin-mediated Selective Progenitor Cell Engraftment in the Isolated-perfused Heart Journal of Molecular and Cellular Cardiology. Jan, 2012 | Pubmed ID: 22047808 Nanofiber-nanorod Composites Exhibiting Light-induced Reversible Lower Critical Solution Temperature Transitions Nanotechnology. Dec, 2011 | Pubmed ID: 22101516 Dynamic Compressive Loading Enhances Cartilage Matrix Synthesis and Distribution and Suppresses Hypertrophy in HMSC-Laden Hyaluronic Acid Hydrogels Tissue Engineering. Part A. Dec, 2011 | Pubmed ID: 21988555 Influence of Injectable Hyaluronic Acid Hydrogel Degradation Behavior on Infarction-induced Ventricular Remodeling Biomacromolecules. Nov, 2011 | Pubmed ID: 21967486 Hydrogel Design for Cartilage Tissue Engineering: a Case Study with Hyaluronic Acid Biomaterials. Dec, 2011 | Pubmed ID: 21903262 Modification of Infarct Material Properties Limits Adverse Ventricular Remodeling The Annals of Thoracic Surgery. Aug, 2011 | Pubmed ID: 21801916 Injectable Acellular Hydrogels for Cardiac Repair Journal of Cardiovascular Translational Research. Oct, 2011 | Pubmed ID: 21710332 Enhanced MSC Chondrogenesis Following Delivery of TGF-β3 from Alginate Microspheres Within Hyaluronic Acid Hydrogels in Vitro and in Vivo Biomaterials. Sep, 2011 | Pubmed ID: 21652067 Gradients with Depth in Electrospun Fibrous Scaffolds for Directed Cell Behavior Biomacromolecules. Jun, 2011 | Pubmed ID: 21528921 Controlled Activation of Morphogenesis to Generate a Functional Human Microvasculature in a Synthetic Matrix Blood. Jul, 2011 | Pubmed ID: 21527523 Hyaluronic Acid Hydrogels for Biomedical Applications Advanced Materials (Deerfield Beach, Fla.). Mar, 2011 | Pubmed ID: 21394792 Enhanced Release of Small Molecules from Near-infrared Light Responsive Polymer-nanorod Composites ACS Nano. Apr, 2011 | Pubmed ID: 21384864 Infarct Restraint to Limit Adverse Ventricular Remodeling Journal of Cardiovascular Translational Research. Feb, 2011 | Pubmed ID: 21161462 Coculture of Human Mesenchymal Stem Cells and Articular Chondrocytes Reduces Hypertrophy and Enhances Functional Properties of Engineered Cartilage Tissue Engineering. Part A. Apr, 2011 | Pubmed ID: 21142648 High-throughput Screening of a Small Molecule Library for Promoters and Inhibitors of Mesenchymal Stem Cell Osteogenic Differentiation Biotechnology and Bioengineering. Jan, 2011 | Pubmed ID: 20824673 The Influence of Fibrous Elastomer Structure and Porosity on Matrix Organization PloS One. 2010 | Pubmed ID: 21203510 Patterning Network Structure to Spatially Control Cellular Remodeling and Stem Cell Fate Within 3-dimensional Hydrogels Biomaterials. Nov, 2010 | Pubmed ID: 20674004 Light-sensitive Polypeptide Hydrogel and Nanorod Composites Small (Weinheim an Der Bergstrasse, Germany). Aug, 2010 | Pubmed ID: 20603882 The Control of Stem Cell Morphology and Differentiation by Hydrogel Surface Wrinkles Biomaterials. Sep, 2010 | Pubmed ID: 20541257 Injectable Hydrogel Properties Influence Infarct Expansion and Extent of Postinfarction Left Ventricular Remodeling in an Ovine Model Proceedings of the National Academy of Sciences of the United States of America. Jun, 2010 | Pubmed ID: 20534527 Controlling Stem Cell Fate with Material Design Advanced Materials (Deerfield Beach, Fla.). Jan, 2010 | Pubmed ID: 20217683 Identification of Osteoconductive and Biodegradable Polymers from a Combinatorial Polymer Library Journal of Biomedical Materials Research. Part A. May, 2010 | Pubmed ID: 20198696 Modular Synthesis of Biodegradable Diblock Copolymers for Designing Functional Polymersomes Journal of the American Chemical Society. Mar, 2010 | Pubmed ID: 20184323 An Anisotropic Nanofiber/microsphere Composite with Controlled Release of Biomolecules for Fibrous Tissue Engineering Biomaterials. May, 2010 | Pubmed ID: 20149432 Electrospun Fibrous Scaffolds with Multiscale and Photopatterned Porosity Macromolecular Bioscience. Mar, 2010 | Pubmed ID: 20014198 Light-responsive Biomaterials: Development and Applications Macromolecular Bioscience. Apr, 2010 | Pubmed ID: 20014197 Biodegradable Fibrous Scaffolds with Diverse Properties by Electrospinning Candidates from a Combinatorial Macromer Library Acta Biomaterialia. Apr, 2010 | Pubmed ID: 19853066 Hydrophilic Elastomeric Biomaterials Based on Resilin-like Polypeptides Soft Matter. 2009 | Pubmed ID: 20543970 Biodegradable Fibrous Scaffolds with Tunable Properties Formed from Photo-cross-linkable Poly(glycerol Sebacate) ACS Applied Materials & Interfaces. Sep, 2009 | Pubmed ID: 20160937 Hydrogel Mediated Delivery of Trophic Factors for Neural Repair Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology. Jan-Feb, 2009 | Pubmed ID: 20049784 Novel Nano-composite Biomaterials That Respond to Light Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference. 2009 | Pubmed ID: 19964957 Tuning Hydrogel Properties for Applications in Tissue Engineering Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference. 2009 | Pubmed ID: 19963530 Fabrication and Modeling of Dynamic Multipolymer Nanofibrous Scaffolds Journal of Biomechanical Engineering. Oct, 2009 | Pubmed ID: 19831482 Macromer Density Influences Mesenchymal Stem Cell Chondrogenesis and Maturation in Photocrosslinked Hyaluronic Acid Hydrogels Osteoarthritis and Cartilage. Dec, 2009 | Pubmed ID: 19631307 The Influence of Degradation Characteristics of Hyaluronic Acid Hydrogels on in Vitro Neocartilage Formation by Mesenchymal Stem Cells Biomaterials. Sep, 2009 | Pubmed ID: 19464053 Light-induced Temperature Transitions in Biodegradable Polymer and Nanorod Composites Small (Weinheim an Der Bergstrasse, Germany). Aug, 2009 | Pubmed ID: 19408258 Engineering on the Straight and Narrow: the Mechanics of Nanofibrous Assemblies for Fiber-reinforced Tissue Regeneration Tissue Engineering. Part B, Reviews. Jun, 2009 | Pubmed ID: 19207040 Influence of Three-dimensional Hyaluronic Acid Microenvironments on Mesenchymal Stem Cell Chondrogenesis Tissue Engineering. Part A. Feb, 2009 | Pubmed ID: 19193129 Differential Maturation and Structure-function Relationships in Mesenchymal Stem Cell- and Chondrocyte-seeded Hydrogels Tissue Engineering. Part A. May, 2009 | Pubmed ID: 19119920 Mechanically Robust and Bioadhesive Collagen and Photocrosslinkable Hyaluronic Acid Semi-interpenetrating Networks Tissue Engineering. Part A. Jul, 2009 | Pubmed ID: 19105604 Engineered Microenvironments for Controlled Stem Cell Differentiation Tissue Engineering. Part A. Feb, 2009 | Pubmed ID: 18694293 Controlled Release of GDNF Reduces Nerve Root-mediated Behavioral Hypersensitivity Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. Jan, 2009 | Pubmed ID: 18634009 Differential Behavior of Auricular and Articular Chondrocytes in Hyaluronic Acid Hydrogels Tissue Engineering. Part A. Jul, 2008 | Pubmed ID: 18407752 Hydrolytically Degradable Hyaluronic Acid Hydrogels with Controlled Temporal Structures Biomacromolecules. Apr, 2008 | Pubmed ID: 18324776 The Potential to Improve Cell Infiltration in Composite Fiber-aligned Electrospun Scaffolds by the Selective Removal of Sacrificial Fibers Biomaterials. May, 2008 | Pubmed ID: 18313138 Electrospinning of Photocrosslinked and Degradable Fibrous Scaffolds Journal of Biomedical Materials Research. Part A. Dec, 2008 | Pubmed ID: 18257065 Controlling Poly(beta-amino Ester) Network Properties Through Macromer Branching Acta Biomaterialia. Mar, 2008 | Pubmed ID: 18033746 Engineering Cartilage Tissue Advanced Drug Delivery Reviews. Jan, 2008 | Pubmed ID: 17976858 Influence of Macromer Molecular Weight and Chemistry on Poly(beta-amino Ester) Network Properties and Initial Cell Interactions Journal of Biomedical Materials Research. Part A. Jun, 2008 | Pubmed ID: 17896761 Hyaluronic Acid Hydrogel for Controlled Self-renewal and Differentiation of Human Embryonic Stem Cells Proceedings of the National Academy of Sciences of the United States of America. Jul, 2007 | Pubmed ID: 17581871 Effects of Auricular Chondrocyte Expansion on Neocartilage Formation in Photocrosslinked Hyaluronic Acid Networks Tissue Engineering. Sep, 2006 | Pubmed ID: 16995800 Influence of Gel Properties on Neocartilage Formation by Auricular Chondrocytes Photoencapsulated in Hyaluronic Acid Networks Journal of Biomedical Materials Research. Part A. Jun, 2006 | Pubmed ID: 16482551 Fragmenting Bulk Hydrogels and Processing into Granular Hydrogels for Biomedical Applications Victoria G. Muir1, Margaret E. Prendergast1, Jason A. Burdick1,2,3 1Department of Bioengineering, School of Engineering and Applied Sciences, University of Pennsylvania, 2BioFrontiers Institute, University of Colorado Boulder, 3Department of Chemical and Biological Engineering, College of Engineering and Applied Science, University of Colorado Boulder JoVE 63867 Bioingegneria
Fragmenting Bulk Hydrogels and Processing into Granular Hydrogels for Biomedical Applications Victoria G. Muir1, Margaret E. Prendergast1, Jason A. Burdick1,2,3 1Department of Bioengineering, School of Engineering and Applied Sciences, University of Pennsylvania, 2BioFrontiers Institute, University of Colorado Boulder, 3Department of Chemical and Biological Engineering, College of Engineering and Applied Science, University of Colorado Boulder JoVE 63867 Bioingegneria