Jennifer E. Van Eyk Advanced Clinical Biosystems Institute, Smidt Heart institute Cedars Sinai Medical Center Biography Publications Institution JoVE Articles Jennifer E. Van Eyk has not added a biography. If you are Jennifer E. Van Eyk and would like to personalize this page please email our Author Liaison for assistance. Publications MitoPlex: A Targeted Multiple Reaction Monitoring Assay for Quantification of a Curated Set of Mitochondrial Proteins Journal of Molecular and Cellular Cardiology. Mar, 2020 | Pubmed ID: 32234390 Identification of Putative Early Atherosclerosis Biomarkers by Unsupervised Deconvolution of Heterogeneous Vascular Proteomes Journal of Proteome Research. Apr, 2020 | Pubmed ID: 32202800 A Dual Workflow to Improve the Proteomic Coverage in Plasma Using Data-Independent Acquisition-MS Journal of Proteome Research. Mar, 2020 | Pubmed ID: 32176508 ACE Overexpression in Myeloid Cells Increases Oxidative Metabolism and Cellular ATP The Journal of Biological Chemistry. Jan, 2020 | Pubmed ID: 31871049 Vascular Biomarkers and Digital Ulcerations in Systemic Sclerosis: Results from a Randomized Controlled Trial of Oral Treprostinil (DISTOL-1) Clinical Rheumatology. Apr, 2020 | Pubmed ID: 31858338 Neuron-generated Thrombin Induces a Protective Astrocyte Response Via Protease Activated Receptors Glia. 02, 2020 | Pubmed ID: 31453648 Mining the Proteome Associated with Rheumatic and Autoimmune Diseases Journal of Proteome Research. 12, 2019 | Pubmed ID: 31599600 Human Proteome Project Mass Spectrometry Data Interpretation Guidelines 3.0 Journal of Proteome Research. 12, 2019 | Pubmed ID: 31599596 A Protocol Integrating Remote Patient Monitoring Patient Reported Outcomes and Cardiovascular Biomarkers NPJ Digital Medicine. 2019 | Pubmed ID: 31508495 Progress on Identifying and Characterizing the Human Proteome: 2019 Metrics from the HUPO Human Proteome Project Journal of Proteome Research. 12, 2019 | Pubmed ID: 31430157 Serum NfL (Neurofilament Light Chain) Levels and Incident Stroke in Adults With Diabetes Mellitus Stroke. 07, 2019 | Pubmed ID: 31138085 Multipotent Fetal-derived Cdx2 Cells from Placenta Regenerate the Heart Proceedings of the National Academy of Sciences of the United States of America. 06, 2019 | Pubmed ID: 31109997 Mapping Citrullinated Sites in Multiple Organs of Mice Using Hypercitrullinated Library Journal of Proteome Research. 05, 2019 | Pubmed ID: 30990720 Acute Neuropathological Consequences of Short-term Mechanical Ventilation in Wild-type and Alzheimer's Disease Mice Critical Care (London, England). 02, 2019 | Pubmed ID: 30795776 PKG1-modified TSC2 Regulates MTORC1 Activity to Counter Adverse Cardiac Stress Nature. 02, 2019 | Pubmed ID: 30700906 In Vitro and In Vivo Proteomic Comparison of Human Neural Progenitor Cell-Induced Photoreceptor Survival Proteomics. 02, 2019 | Pubmed ID: 30515959 Precision Medicine: Role of Proteomics in Changing Clinical Management and Care Journal of Proteome Research. 01, 2019 | Pubmed ID: 30296097 Precision Medicine Circulation. 11, 2018 | Pubmed ID: 30571512 Cardiac Troponins May Be Irreversibly Modified by Glycation: Novel Potential Mechanisms of Cardiac Performance Modulation Scientific Reports. 10, 2018 | Pubmed ID: 30382112 Diabetes with Heart Failure Increases Methylglyoxal Modifications in the Sarcomere, Which Inhibit Function JCI Insight. 10, 2018 | Pubmed ID: 30333300 Identifying High-Priority Proteins Across the Human Diseasome Using Semantic Similarity Journal of Proteome Research. 12, 2018 | Pubmed ID: 30256117 Sex Differences in Ischemic Heart Disease and Heart Failure Biomarkers Biology of Sex Differences. 09, 2018 | Pubmed ID: 30223899 Phospho-Proteomic Analysis of Cardiac Dyssynchrony and Resynchronization Therapy Proteomics. Aug, 2018 | Pubmed ID: 30129105 Progress on Identifying and Characterizing the Human Proteome: 2018 Metrics from the HUPO Human Proteome Project Journal of Proteome Research. Aug, 2018 | Pubmed ID: 30099871 Proteomics Reveals Rictor As a Non-Canonical TGFB Signaling Target During Aneurysm Progression in Marfan Mice American Journal of Physiology. Heart and Circulatory Physiology. Jul, 2018 | Pubmed ID: 30004239 Proteomic Architecture of Human Coronary and Aortic Atherosclerosis Circulation. Jun, 2018 | Pubmed ID: 29915101 Evaluating Utility and Compliance in a Patient-based EHealth Study Using Continuous-time Heart Rate and Activity Trackers Journal of the American Medical Informatics Association : JAMIA. May, 2018 | Pubmed ID: 29850807 Precision Profiling of the Cardiovascular Post-Translationally Modified Proteome: Where There Is a Will, There Is a Way Circulation Research. Apr, 2018 | Pubmed ID: 29700069 Newt Cells Secrete Extracellular Vesicles with Therapeutic Bioactivity in Mammalian Cardiomyocytes Journal of Extracellular Vesicles. 2018 | Pubmed ID: 29696078 A Proteomics Workflow for Dual Labeling Biotin Switch Assay to Detect and Quantify Protein S-Nitroylation Methods in Molecular Biology (Clifton, N.J.). 2018 | Pubmed ID: 29600453 Genome-wide Analyses Identify KIF5A As a Novel ALS Gene Neuron. Mar, 2018 | Pubmed ID: 29566793 Protein -Nitrosylation Controls Glycogen Synthase Kinase 3β Function Independent of Its Phosphorylation State Circulation Research. May, 2018 | Pubmed ID: 29563102 Desmin Phosphorylation Triggers Preamyloid Oligomers Formation and Myocyte Dysfunction in Acquired Heart Failure Circulation Research. May, 2018 | Pubmed ID: 29483093 How Many Human Proteoforms Are There? Nature Chemical Biology. Feb, 2018 | Pubmed ID: 29443976 Molecular Profile of Priapism Associated with Low Nitric Oxide Bioavailability Journal of Proteome Research. 03, 2018 | Pubmed ID: 29394072 Guidelines for Experimental Models of Myocardial Ischemia and Infarction American Journal of Physiology. Heart and Circulatory Physiology. Apr, 2018 | Pubmed ID: 29351451 The Library of Integrated Network-Based Cellular Signatures NIH Program: System-Level Cataloging of Human Cells Response to Perturbations Cell Systems. Jan, 2018 | Pubmed ID: 29199020 Association of Quantitative Metastatic Lymph Node Burden With Survival in Hypopharyngeal and Laryngeal Cancer JAMA Oncology. Jul, 2018 | Pubmed ID: 29192305 Highly Reproducible Automated Proteomics Sample Preparation Workflow for Quantitative Mass Spectrometry Journal of Proteome Research. 01, 2018 | Pubmed ID: 29083196 Transient Receptor Potential Channel 6 Regulates Abnormal Cardiac S-nitrosylation in Duchenne Muscular Dystrophy Proceedings of the National Academy of Sciences of the United States of America. 12, 2017 | Pubmed ID: 29187535 Metastatic Lymph Node Burden and Survival in Oral Cavity Cancer Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Nov, 2017 | Pubmed ID: 28880746 Advances in Quantifying Apolipoproteins Using LC-MS/MS Technology: Implications for the Clinic Expert Review of Proteomics. 10, 2017 | Pubmed ID: 28870113 Profiling B-Type Natriuretic Peptide Cleavage Peptidoforms in Human Plasma by Capillary Electrophoresis with Electrospray Ionization Mass Spectrometry Journal of Proteome Research. Dec, 2017 | Pubmed ID: 28861997 Exploring Ribosome Composition and Newly Synthesized Proteins Through Proteomics and Potential Biomedical Applications Expert Review of Proteomics. 06, 2017 | Pubmed ID: 28532181 Mapping Biological Networks from Quantitative Data-Independent Acquisition Mass Spectrometry: Data to Knowledge Pipelines Methods in Molecular Biology (Clifton, N.J.). 2017 | Pubmed ID: 28150249 A Roadmap to Successful Clinical Proteomics Clinical Chemistry. Jan, 2017 | Pubmed ID: 27864386 Extracellular Matrix Downregulation in the Drosophila Heart Preserves Contractile Function and Improves Lifespan Matrix Biology : Journal of the International Society for Matrix Biology. Oct, 2017 | Pubmed ID: 27793636 A Novel, Multiplexed Targeted Mass Spectrometry Assay for Quantification of Complement Factor H (CFH) Variants and CFH-related Proteins 1-5 in Human Plasma Proteomics. Mar, 2017 | Pubmed ID: 27647805 The Proteome of Normal Human Retrobulbar Optic Nerve and Sclera Proteomics. 10, 2016 | Pubmed ID: 27538499 Human Proteome Project Mass Spectrometry Data Interpretation Guidelines 2.1 Journal of Proteome Research. 11, 2016 | Pubmed ID: 27490519 Effect of Peptide Assay Library Size and Composition in Targeted Data-independent Acquisition-MS Analyses Proteomics. 08, 2016 | Pubmed ID: 27432805 Data-Driven Approach To Determine Popular Proteins for Targeted Proteomics Translation of Six Organ Systems Journal of Proteome Research. 11, 2016 | Pubmed ID: 27356587 Discordant Signaling and Autophagy Response to Fasting in Hearts of Obese Mice: Implications for Ischemia Tolerance American Journal of Physiology. Heart and Circulatory Physiology. 07, 2016 | Pubmed ID: 27199111 Profilin Modulates Sarcomeric Organization and Mediates Cardiomyocyte Hypertrophy Cardiovascular Research. May, 2016 | Pubmed ID: 26956799 Methods for SWATH™: Data Independent Acquisition on TripleTOF Mass Spectrometers Methods in Molecular Biology (Clifton, N.J.). 2016 | Pubmed ID: 26867750 Multiple and Selective Reaction Monitoring Using Triple Quadrupole Mass Spectrometer: Preclinical Large Cohort Analysis Methods in Molecular Biology (Clifton, N.J.). 2016 | Pubmed ID: 26867749 Defining the Proteome of Human Iris, Ciliary Body, Retinal Pigment Epithelium, and Choroid Proteomics. Apr, 2016 | Pubmed ID: 26834087 Recommendations for the Generation, Quantification, Storage, and Handling of Peptides Used for Mass Spectrometry-Based Assays Clinical Chemistry. Jan, 2016 | Pubmed ID: 26719571 Protein Kinase G Signaling in Cardiac Pathophysiology: Impact of Proteomics on Clinical Trials Proteomics. Mar, 2016 | Pubmed ID: 26670943 An Empirical Approach to Signature Peptide Choice for Selected Reaction Monitoring: Quantification of Uromodulin in Urine Clinical Chemistry. Jan, 2016 | Pubmed ID: 26589548 A Novel Phosphorylation Site at Ser130 Adjacent to the Pseudosubstrate Domain Contributes to the Activation of Protein Kinase C-δ The Biochemical Journal. Feb, 2016 | Pubmed ID: 26546672 Pacemaker-induced Transient Asynchrony Suppresses Heart Failure Progression Science Translational Medicine. Dec, 2015 | Pubmed ID: 26702095 Dual Labeling Biotin Switch Assay to Reduce Bias Derived From Different Cysteine Subpopulations: A Method to Maximize S-Nitrosylation Detection Circulation Research. Oct, 2015 | Pubmed ID: 26338901 Biomarkers of Pulmonary Hypertension in Patients with Scleroderma: a Case-control Study Arthritis Research & Therapy. Aug, 2015 | Pubmed ID: 26245195 Identification of a Set of Conserved Eukaryotic Internal Retention Time Standards for Data-independent Acquisition Mass Spectrometry Molecular & Cellular Proteomics : MCP. Oct, 2015 | Pubmed ID: 26199342 Priorities and Trends in the Study of Proteins in Eye Research, 1924-2014 Proteomics. Clinical Applications. Dec, 2015 | Pubmed ID: 26123431 Citrullination of Myofilament Proteins in Heart Failure Cardiovascular Research. Nov, 2015 | Pubmed ID: 26113265 Vinculin Network-mediated Cytoskeletal Remodeling Regulates Contractile Function in the Aging Heart Science Translational Medicine. Jun, 2015 | Pubmed ID: 26084806 Identification of Glycoproteins Containing Specific Glycans Using a Lectin-chemical Method Analytical Chemistry. 2015 | Pubmed ID: 25837443 Universal Therapeutic Targeting of Age-related Protein Quality Control System Dysfunction in Chronic Diseases? Trends in Cardiovascular Medicine. Apr, 2015 | Pubmed ID: 25802225 A Novel Phosphorylation Site, Serine 199, in the C-terminus of Cardiac Troponin I Regulates Calcium Sensitivity and Susceptibility to Calpain-induced Proteolysis Journal of Molecular and Cellular Cardiology. May, 2015 | Pubmed ID: 25771144 Cross-Disciplinary Biomarkers Research: Lessons Learned by the CKD Biomarkers Consortium Clinical Journal of the American Society of Nephrology : CJASN. May, 2015 | Pubmed ID: 25739849 Assessing Amide Proton Transfer (APT) MRI Contrast Origins in 9 L Gliosarcoma in the Rat Brain Using Proteomic Analysis Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging. Aug, 2015 | Pubmed ID: 25622812 Emerging Proteomic Technologies for Elucidating Context-dependent Cellular Signaling Events: A Big Challenge of Tiny Proportions Proteomics. May, 2015 | Pubmed ID: 25545106 The Proteome of Human Retina Proteomics. Feb, 2015 | Pubmed ID: 25407473 Identification of Cardiac Myofilament Protein Isoforms Using Multiple Mass Spectrometry Based Approaches Proteomics. Clinical Applications. Aug, 2014 | Pubmed ID: 24974818 Redox Signaling and Protein Phosphorylation in Mitochondria: Progress and Prospects Journal of Bioenergetics and Biomembranes. Apr, 2009 | Pubmed ID: 19440831 自動ワークステーションを用いた質量分析のためのプラズマサンプル調製 Qin Fu1, Casey W. Johnson1, Bhagya K. Wijayawardena2, Michael P. Kowalski2, Miranda Kheradmand2, Jennifer E. Van Eyk1 1Advanced Clinical Biosystems Institute, Smidt Heart institute, Cedars Sinai Medical Center, 2Beckman Coulter Life Sciences JoVE 59842 Biochimica
自動ワークステーションを用いた質量分析のためのプラズマサンプル調製 Qin Fu1, Casey W. Johnson1, Bhagya K. Wijayawardena2, Michael P. Kowalski2, Miranda Kheradmand2, Jennifer E. Van Eyk1 1Advanced Clinical Biosystems Institute, Smidt Heart institute, Cedars Sinai Medical Center, 2Beckman Coulter Life Sciences JoVE 59842 Biochimica