Jian Q. Feng Department of Biomedical Sciences Texas A&M University College of Dentistry Biography Publications Institution JoVE Articles Jian Q. Feng has not added a biography. If you are Jian Q. Feng and would like to personalize this page please email our Author Liaison for assistance. Publications Essential Roles of Bone Morphogenetic Protein-1 and Mammalian Tolloid-like 1 in Postnatal Root Dentin Formation Journal of Endodontics. Jan, 2017 | Pubmed ID: 27847137 MiRNA-101 Acts As a Tumor Suppressor in Oral Squamous Cell Carcinoma by Targeting CX Chemokine Receptor 7 American Journal of Translational Research. 2016 | Pubmed ID: 27904690 Dmp1 Null Mice Develop a Unique Osteoarthritis-like Phenotype International Journal of Biological Sciences. 2016 | Pubmed ID: 27766035 Implant-derived Magnesium Induces Local Neuronal Production of CGRP to Improve Bone-fracture Healing in Rats Nature Medicine. Oct, 2016 | Pubmed ID: 27571347 Inactivation of Fam20B in Joint Cartilage Leads to Chondrosarcoma and Postnatal Ossification Defects Scientific Reports. Jul, 2016 | Pubmed ID: 27405802 Targeted Disruption of BMP Signaling Through Type IA Receptor (BMPR1A) in Osteocyte Suppresses SOST and RANKL, Leading to Dramatic Increase in Bone Mass, Bone Mineral Density and Mechanical Strength Bone. Oct, 2016 | Pubmed ID: 27402532 Sclerostin Antibody Preserves the Morphology and Structure of Osteocytes and Blocks the Severe Skeletal Deterioration After Motor-Complete Spinal Cord Injury in Rats Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Jul, 2016 | Pubmed ID: 27377772 The Biological Function of Type I Receptors of Bone Morphogenetic Protein in Bone Bone Research. 2016 | Pubmed ID: 27088043 Sclerostin Antibody (Scl-Ab) Improves Osteomalacia Phenotype in Dentin Matrix Protein 1(Dmp1) Knockout Mice with Little Impact on Serum Levels of Phosphorus and FGF23 Matrix Biology : Journal of the International Society for Matrix Biology. May-Jul, 2016 | Pubmed ID: 26721590 Expression of the Invertebrate Sea Urchin P16 Protein into Mammalian MC3T3 Osteoblasts Transforms and Reprograms Them into "osteocyte-like" Cells Journal of Experimental Zoology. Part B, Molecular and Developmental Evolution. Jan, 2016 | Pubmed ID: 26581835 Critical Roles of Periostin in the Process of Orthodontic Tooth Movement European Journal of Orthodontics. Aug, 2016 | Pubmed ID: 26446403 Activation of Receptor Activator of Nuclear Factor-κB Ligand and Matrix Metalloproteinase Production in Periodontal Fibroblasts by Endothelin Signaling Journal of Periodontology. Jan, 2016 | Pubmed ID: 26376946 The Ultrastructural Relationship Between Osteocytes and Dental Implants Following Osseointegration Clinical Implant Dentistry and Related Research. Apr, 2016 | Pubmed ID: 25039329 Expression Analysis of α-smooth Muscle Actin and Tenascin-C in the Periodontal Ligament Under Orthodontic Loading or in Vitro Culture International Journal of Oral Science. Dec, 2015 | Pubmed ID: 26674425 Genetic Influences on Temporomandibular Joint Development and Growth Current Topics in Developmental Biology. 2015 | Pubmed ID: 26589922 The in Vivo Role of DMP-1 and Serum Phosphate on Bone Mineral Composition Bone. Dec, 2015 | Pubmed ID: 26303287 Bmpr1a Signaling in Cartilage Development and Endochondral Bone Formation Vitamins and Hormones. 2015 | Pubmed ID: 26279380 Sclerostin Antibody Preserves the Morphology and Structure of Osteocytes and Blocks the Severe Skeletal Deterioration After Motor-complete Spinal Cord Injury in Rats Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Nov, 2015 | Pubmed ID: 25974843 Phytomolecule Icaritin Incorporated PLGA/TCP Scaffold for Steroid-associated Osteonecrosis: Proof-of-concept for Prevention of Hip Joint Collapse in Bipedal Emus and Mechanistic Study in Quadrupedal Rabbits Biomaterials. Aug, 2015 | Pubmed ID: 25968462 Removal of SOST or Blocking Its Product Sclerostin Rescues Defects in the Periodontitis Mouse Model FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jul, 2015 | Pubmed ID: 25757567 Osterix Controls Cementoblast Differentiation Through Downregulation of Wnt-signaling Via Enhancing DKK1 Expression International Journal of Biological Sciences. 2015 | Pubmed ID: 25678852 Complete Pulpodentin Complex Regeneration by Modulating the Stiffness of Biomimetic Matrix Acta Biomaterialia. Apr, 2015 | Pubmed ID: 25644448 Essential Role of Osterix for Tooth Root but Not Crown Dentin Formation Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Apr, 2015 | Pubmed ID: 25349111 Osteoblast-derived WNT16 Represses Osteoclastogenesis and Prevents Cortical Bone Fragility Fractures Nature Medicine. Nov, 2014 | Pubmed ID: 25306233 A Novel Way to Statistically Analyze Morphologic Changes in Dmp1-null Osteocytes Connective Tissue Research. Aug, 2014 | Pubmed ID: 25158197 Critical Role of Bmpr1a in Mandibular Condyle Growth Connective Tissue Research. Aug, 2014 | Pubmed ID: 25158185 Twist1- and Twist2-haploinsufficiency Results in Reduced Bone Formation PloS One. 2014 | Pubmed ID: 24971743 Constitutive Nuclear Expression of Dentin Matrix Protein 1 Fails to Rescue the Dmp1-null Phenotype The Journal of Biological Chemistry. Aug, 2014 | Pubmed ID: 24917674 Overexpression of Dmp1 Fails to Rescue the Bone and Dentin Defects in Fam20C Knockout Mice Connective Tissue Research. Aug, 2014 | Pubmed ID: 24874551 Magnesium-containing Nanostructured Hybrid Scaffolds for Enhanced Dentin Regeneration Tissue Engineering. Part A. Sep, 2014 | Pubmed ID: 24593189 Beta-galactosidase Staining in the Skeleton Methods in Molecular Biology (Clifton, N.J.). 2014 | Pubmed ID: 24482173 Induced Ablation of Bmp1 and Tll1 Produces Osteogenesis Imperfecta in Mice Human Molecular Genetics. Jun, 2014 | Pubmed ID: 24419319 Impact of Extracellular Matrix Derived from Osteoarthritis Subchondral Bone Osteoblasts on Osteocytes: Role of Integrinβ1 and Focal Adhesion Kinase Signaling Cues Arthritis Research & Therapy. Oct, 2013 | Pubmed ID: 24289792 Steroid-associated Hip Joint Collapse in Bipedal Emus PloS One. 2013 | Pubmed ID: 24204675 BMP Receptor 1A Determines the Cell Fate of the Postnatal Growth Plate International Journal of Biological Sciences. 2013 | Pubmed ID: 24163588 Failure to Process Dentin Sialophosphoprotein into Fragments Leads to Periodontal Defects in Mice European Journal of Oral Sciences. Dec, 2013 | Pubmed ID: 24112131 Cessation of Epithelial Bmp Signaling Switches the Differentiation of Crown Epithelia to the Root Lineage in a β-catenin-dependent Manner Molecular and Cellular Biology. Dec, 2013 | Pubmed ID: 24081330 The Plastic Nature of the Human Bone-periodontal Ligament-tooth Fibrous Joint Bone. Dec, 2013 | Pubmed ID: 24063947 Role of the NH2 -terminal Fragment of Dentin Sialophosphoprotein in Dentinogenesis European Journal of Oral Sciences. Apr, 2013 | Pubmed ID: 23489896 Biomimetic Engineering of Nanofibrous Gelatin Scaffolds with Noncollagenous Proteins for Enhanced Bone Regeneration Tissue Engineering. Part A. Aug, 2013 | Pubmed ID: 23469769 Osteocyte Regulation of Phosphate Homeostasis and Bone Mineralization Underlies the Pathophysiology of the Heritable Disorders of Rickets and Osteomalacia Bone. Jun, 2013 | Pubmed ID: 23403405 The Rescue of Dentin Matrix Protein 1 (DMP1)-deficient Tooth Defects by the Transgenic Expression of Dentin Sialophosphoprotein (DSPP) Indicates That DSPP is a Downstream Effector Molecule of DMP1 in Dentinogenesis The Journal of Biological Chemistry. Mar, 2013 | Pubmed ID: 23349460 Estrogen Receptor-α in Osteocytes is Important for Trabecular Bone Formation in Male Mice Proceedings of the National Academy of Sciences of the United States of America. Feb, 2013 | Pubmed ID: 23345419 Osteoblast Lineage-specific Effects of Notch Activation in the Skeleton Endocrinology. Feb, 2013 | Pubmed ID: 23275471 Myelopoiesis is Regulated by Osteocytes Through Gsα-dependent Signaling Blood. Feb, 2013 | Pubmed ID: 23160461 Hexa-D-arginine Treatment Increases 7B2•PC2 Activity in Hyp-mouse Osteoblasts and Rescues the HYP Phenotype Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Jan, 2013 | Pubmed ID: 22886699 FAM20C Plays an Essential Role in the Formation of Murine Teeth The Journal of Biological Chemistry. Oct, 2012 | Pubmed ID: 22936805 Protective Roles of DMP1 in High Phosphate Homeostasis PloS One. 2012 | Pubmed ID: 22879941 Proteolytic Processing of Dentin Sialophosphoprotein (DSPP) is Essential to Dentinogenesis The Journal of Biological Chemistry. Aug, 2012 | Pubmed ID: 22798071 Inactivation of a Novel FGF23 Regulator, FAM20C, Leads to Hypophosphatemic Rickets in Mice PLoS Genetics. 2012 | Pubmed ID: 22615579 Normocalcemia is Maintained in Mice Under Conditions of Calcium Malabsorption by Vitamin D-induced Inhibition of Bone Mineralization The Journal of Clinical Investigation. May, 2012 | Pubmed ID: 22523068 Phenotypic Characterization of Osteoarthritic Osteocytes from the Sclerotic Zones: a Possible Pathological Role in Subchondral Bone Sclerosis International Journal of Biological Sciences. 2012 | Pubmed ID: 22419886 Genetic Evidence for the Vital Function of Osterix in Cementogenesis Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. May, 2012 | Pubmed ID: 22246569 Partial Blocking of Mouse DSPP Processing by Substitution of Gly(451)-Asp(452) Bond Suggests the Presence of Secondary Cleavage Site(s) Connective Tissue Research. 2012 | Pubmed ID: 22175728 Expression of Dentine Sialophosphoprotein in Mouse Nasal Cartilage Archives of Oral Biology. Jun, 2012 | Pubmed ID: 22088564 Meox2Cre-mediated Disruption of CSF-1 Leads to Osteopetrosis and Osteocyte Defects Bone. Jan, 2012 | Pubmed ID: 21958845 GEP Constitutes a Negative Feedback Loop with MyoD and Acts As a Novel Mediator in Controlling Skeletal Muscle Differentiation Cellular and Molecular Life Sciences : CMLS. Dec, 2011 | Pubmed ID: 22179841 Expression of Dentin Sialophosphoprotein in Non-mineralized Tissues The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. Nov, 2011 | Pubmed ID: 22043023 Evidence for Osteocyte Regulation of Bone Homeostasis Through RANKL Expression Nature Medicine. Sep, 2011 | Pubmed ID: 21909105 Roles of DMP1 Processing in Osteogenesis, Dentinogenesis and Chondrogenesis Cells, Tissues, Organs. 2011 | Pubmed ID: 21555863 Unique Roles of Phosphorus in Endochondral Bone Formation and Osteocyte Maturation Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. May, 2011 | Pubmed ID: 21542006 Bone Proteins PHEX and DMP1 Regulate Fibroblastic Growth Factor Fgf23 Expression in Osteocytes Through a Common Pathway Involving FGF Receptor (FGFR) Signaling FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Aug, 2011 | Pubmed ID: 21507898 FGF23 in Skeletal Modeling and Remodeling Current Osteoporosis Reports. Jun, 2011 | Pubmed ID: 21404002 The Growth Factor Progranulin Binds to TNF Receptors and is Therapeutic Against Inflammatory Arthritis in Mice Science (New York, N.Y.). Apr, 2011 | Pubmed ID: 21393509 A Novel Role of Periostin in Postnatal Tooth Formation and Mineralization The Journal of Biological Chemistry. Feb, 2011 | Pubmed ID: 21131362 The Biological Function of DMP-1 in Osteocyte Maturation is Mediated by Its 57-kDa C-terminal Fragment Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Feb, 2011 | Pubmed ID: 20734454 GEP, a Local Growth Factor, is Critical for Odontogenesis and Amelogenesis International Journal of Biological Sciences. 2010 | Pubmed ID: 21152114 Circling Behavior Developed in Dmp1 Null Mice is Due to Bone Defects in the Vestibular Apparatus International Journal of Biological Sciences. Sep, 2010 | Pubmed ID: 20877695 Distribution of Small Integrin-binding Ligand, N-linked Glycoproteins (SIBLING) in the Articular Cartilage of the Rat Femoral Head The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. Nov, 2010 | Pubmed ID: 20679519 Failure to Process Dentin Matrix Protein 1 (DMP1) into Fragments Leads to Its Loss of Function in Osteogenesis The Journal of Biological Chemistry. Oct, 2010 | Pubmed ID: 20663874 Expression of FAM20C in the Osteogenesis and Odontogenesis of Mouse The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. Nov, 2010 | Pubmed ID: 20644212 Multiple Functions of Osterix Are Required for Bone Growth and Homeostasis in Postnatal Mice Proceedings of the National Academy of Sciences of the United States of America. Jul, 2010 | Pubmed ID: 20615976 DMP1 C-terminal Mutant Mice Recapture the Human ARHR Tooth Phenotype Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Oct, 2010 | Pubmed ID: 20499360 Osteocyte Wnt/beta-catenin Signaling is Required for Normal Bone Homeostasis Molecular and Cellular Biology. Jun, 2010 | Pubmed ID: 20404086 Granulin Epithelin Precursor: a Bone Morphogenic Protein 2-inducible Growth Factor That Activates Erk1/2 Signaling and JunB Transcription Factor in Chondrogenesis FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jun, 2010 | Pubmed ID: 20124436 A New Osteopetrosis Mutant Mouse Strain (ntl) with Odontoma-like Proliferations and Lack of Tooth Roots European Journal of Oral Sciences. Dec, 2009 | Pubmed ID: 20121924 Do Osteocytes Contribute to Phosphate Homeostasis? Current Opinion in Nephrology and Hypertension. Jul, 2009 | Pubmed ID: 19448536 Studies of the DMP1 57-kDa Functional Domain Both in Vivo and in Vitro Cells, Tissues, Organs. 2009 | Pubmed ID: 18728349 Tooth Agenesis in a Family and Homozygous PAX9 Mutation in Exon 3: a Case Report World Journal of Orthodontics. 2008 | Pubmed ID: 19641755 BMP Signaling Negatively Regulates Bone Mass Through Sclerostin by Inhibiting the Canonical Wnt Pathway Development (Cambridge, England). Nov, 2008 | Pubmed ID: 18927151 Disruption of BMP Signaling in Osteoblasts Through Type IA Receptor (BMPRIA) Increases Bone Mass Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Dec, 2008 | Pubmed ID: 18684091 Pathogenic Role of Fgf23 in Dmp1-null Mice American Journal of Physiology. Endocrinology and Metabolism. Aug, 2008 | Pubmed ID: 18559986 Generation of a Conditional Null Allele for Dmp1 in Mouse Genesis (New York, N.Y. : 2000). Feb, 2008 | Pubmed ID: 18257058 Aberrant Phex Function in Osteoblasts and Osteocytes Alone Underlies Murine X-linked Hypophosphatemia The Journal of Clinical Investigation. Feb, 2008 | Pubmed ID: 18172553 Extracellular Matrix Made by Bone Marrow Cells Facilitates Expansion of Marrow-derived Mesenchymal Progenitor Cells and Prevents Their Differentiation into Osteoblasts Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Dec, 2007 | Pubmed ID: 17680726 Cartilage Oligomeric Matrix Protein Associates with Granulin-epithelin Precursor (GEP) and Potentiates GEP-stimulated Chondrocyte Proliferation The Journal of Biological Chemistry. Apr, 2007 | Pubmed ID: 17307734 Rescue of Odontogenesis in Dmp1-deficient Mice by Targeted Re-expression of DMP1 Reveals Roles for DMP1 in Early Odontogenesis and Dentin Apposition in Vivo Developmental Biology. Mar, 2007 | Pubmed ID: 17196192 Loss of DMP1 Causes Rickets and Osteomalacia and Identifies a Role for Osteocytes in Mineral Metabolism Nature Genetics. Nov, 2006 | Pubmed ID: 17033621 Bone Morphogenetic Protein Signaling Inhibits Hair Follicle Anagen Induction by Restricting Epithelial Stem/progenitor Cell Activation and Expansion Stem Cells (Dayton, Ohio). Dec, 2006 | Pubmed ID: 16960130 E11/gp38 Selective Expression in Osteocytes: Regulation by Mechanical Strain and Role in Dendrite Elongation Molecular and Cellular Biology. Jun, 2006 | Pubmed ID: 16738320 Functional Consequences of Interactions Between Pax9 and Msx1 Genes in Normal and Abnormal Tooth Development The Journal of Biological Chemistry. Jul, 2006 | Pubmed ID: 16651263 Differential Regulation of Dentin Matrix Protein 1 Expression During Odontogenesis Cells, Tissues, Organs. 2005 | Pubmed ID: 16612089 Periostin Null Mice Exhibit Dwarfism, Incisor Enamel Defects, and an Early-onset Periodontal Disease-like Phenotype Molecular and Cellular Biology. Dec, 2005 | Pubmed ID: 16314533 DMP1 Depletion Decreases Bone Mineralization in Vivo: an FTIR Imaging Analysis Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Dec, 2005 | Pubmed ID: 16294270 Dentin Matrix Protein 1 Gene Cis-regulation: Use in Osteocytes to Characterize Local Responses to Mechanical Loading in Vitro and in Vivo The Journal of Biological Chemistry. May, 2005 | Pubmed ID: 15728181 Dmp1-deficient Mice Display Severe Defects in Cartilage Formation Responsible for a Chondrodysplasia-like Phenotype The Journal of Biological Chemistry. Feb, 2005 | Pubmed ID: 15590631 Critical Role of Calbindin-D28k in Calcium Homeostasis Revealed by Mice Lacking Both Vitamin D Receptor and Calbindin-D28k The Journal of Biological Chemistry. Dec, 2004 | Pubmed ID: 15456794 Deletion of Dentin Matrix Protein-1 Leads to a Partial Failure of Maturation of Predentin into Dentin, Hypomineralization, and Expanded Cavities of Pulp and Root Canal During Postnatal Tooth Development The Journal of Biological Chemistry. Apr, 2004 | Pubmed ID: 14966118 Identification of the Haematopoietic Stem Cell Niche and Control of the Niche Size Nature. Oct, 2003 | Pubmed ID: 14574412 NF-kappaB Specifically Activates BMP-2 Gene Expression in Growth Plate Chondrocytes in Vivo and in a Chondrocyte Cell Line in Vitro The Journal of Biological Chemistry. Aug, 2003 | Pubmed ID: 12759356 Mechanical Loading Stimulates Dentin Matrix Protein 1 (DMP1) Expression in Osteocytes in Vivo Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. May, 2003 | Pubmed ID: 12733719 Dissection of Promoter Control Modules That Direct Bmp4 Expression in the Epithelium-derived Components of Hair Follicles Biochemical and Biophysical Research Communications. May, 2002 | Pubmed ID: 12054672 Co-localization of Cell Lineage Markers and the Tomato Signal Yan Jing1, Robert J. Hinton1, Kevin S. Chan1, Jian Q. Feng1 1Department of Biomedical Sciences, Texas A&M University College of Dentistry JoVE 54982 Biologia dello sviluppo
Co-localization of Cell Lineage Markers and the Tomato Signal Yan Jing1, Robert J. Hinton1, Kevin S. Chan1, Jian Q. Feng1 1Department of Biomedical Sciences, Texas A&M University College of Dentistry JoVE 54982 Biologia dello sviluppo