Joanne Young

Publications

• Colorectal and Other Cancer Risks for Carriers and Noncarriers From Families With a DNA Mismatch Repair Gene Mutation: A Prospective Cohort Study
  Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Feb, 2012  |   Pubmed ID: 22331944
• Immunohistochemical Testing of Conventional Adenomas for Loss of Expression of Mismatch Repair Proteins in Lynch Syndrome Mutation Carriers: a Case Series from the Australasian Site of the Colon Cancer Family Registry
  Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc. Feb, 2012  |   Pubmed ID: 22322191
• KRAS Mutations in Ovarian Low-grade Endometrioid Adenocarcinoma: Association with Concurrent Endometriosis
  Human Pathology. Feb, 2012  |   Pubmed ID: 22305241
• Cancer Risks for the Relatives of Colorectal Cancer Cases with a Methylated MLH1 Promoter Region: Data from the Colorectal Cancer Family Registry
  Cancer Prevention Research (Philadelphia, Pa.). Feb, 2012  |   Pubmed ID: 22144422
• Refinement of the Associations Between Risk of Colorectal Cancer and Polymorphisms on Chromosomes 1q41 and 12q13.13
  Human Molecular Genetics. Feb, 2012  |   Pubmed ID: 22076443
• Molecular Change That Distinguishes Traditional Serrated Adenomas from Sessile Serrated Adenomas
  Journal of Gastroenterology and Hepatology. Oct, 2011  |   Pubmed ID: 21950744
• Hyperplastic Polyp of the Duodenum: a Report of 9 Cases with Immunohistochemical and Molecular Findings
  Human Pathology. Dec, 2011  |   Pubmed ID: 21733555
• Serrated Polyposis: an Enigmatic Model of Colorectal Cancer Predisposition
  Pathology Research International. 2011  |   Pubmed ID: 21660283
• Multiple Common Susceptibility Variants Near BMP Pathway Loci GREM1, BMP4, and BMP2 Explain Part of the Missing Heritability of Colorectal Cancer
  PLoS Genetics. Jun, 2011  |   Pubmed ID: 21655089
• Determining the Frequency of De Novo Germline Mutations in DNA Mismatch Repair Genes
  Journal of Medical Genetics. Aug, 2011  |   Pubmed ID: 21636617
• Quality Assessment and Correlation of Microsatellite Instability and Immunohistochemical Markers Among Population- and Clinic-based Colorectal Tumors Results from the Colon Cancer Family Registry
  The Journal of Molecular Diagnostics : JMD. May, 2011  |   Pubmed ID: 21497289
• Report of Endometrial Cancer in Australian BRCA1 and BRCA2 Mutation-positive Families
  Twin Research and Human Genetics : the Official Journal of the International Society for Twin Studies. Apr, 2011  |   Pubmed ID: 21425892
• Body Mass Index in Early Adulthood and Endometrial Cancer Risk for Mismatch Repair Gene Mutation Carriers
  Obstetrics and Gynecology. Apr, 2011  |   Pubmed ID: 21422863
• Mutation Deep Within an Intron of MSH2 Causes Lynch Syndrome
  Familial Cancer. Jun, 2011  |   Pubmed ID: 21360204
• Investigating the Potential Role of Genetic and Epigenetic Variation of DNA Methyltransferase Genes in Hyperplastic Polyposis Syndrome
  PloS One. 2011  |   Pubmed ID: 21347319
• Promoter Methylation of Wnt Antagonists DKK1 and SFRP1 is Associated with Opposing Tumor Subtypes in Two Large Populations of Colorectal Cancer Patients
  Carcinogenesis. May, 2011  |   Pubmed ID: 21304055
• Metachronous Colorectal Cancer Risk for Mismatch Repair Gene Mutation Carriers: the Advantage of More Extensive Colon Surgery
  Gut. Jul, 2011  |   Pubmed ID: 21193451
• Linkage to Chromosome 2q32.2-q33.3 in Familial Serrated Neoplasia (Jass Syndrome)
  Familial Cancer. Jun, 2011  |   Pubmed ID: 21165777
• Cancer Risks for Monoallelic MUTYH Mutation Carriers with a Family History of Colorectal Cancer
  International Journal of Cancer. Journal International Du Cancer. Dec, 2010  |   Pubmed ID: 21171015
• Risk Factors: Hyperplastic Polyposis Syndrome and Risk of Colorectal Cancer
  Nature Reviews. Gastroenterology & Hepatology. Nov, 2010  |   Pubmed ID: 21042338
• Risk Factors for Colorectal Cancer in Patients with Multiple Serrated Polyps: a Cross-sectional Case Series from Genetics Clinics
  PloS One. 2010  |   Pubmed ID: 20661287
• A Day at a Time: Caregiving on the Edge in Advanced COPD
  International Journal of Chronic Obstructive Pulmonary Disease. 2010  |   Pubmed ID: 20631814
• Confirmation of Linkage to and Localization of Familial Colon Cancer Risk Haplotype on Chromosome 9q22
  Cancer Research. Jul, 2010  |   Pubmed ID: 20551049
• Risk of Endometrial Cancer for Women Diagnosed with HNPCC-related Colorectal Carcinoma
  International Journal of Cancer. Journal International Du Cancer. Dec, 2010  |   Pubmed ID: 20533284
• Lessons from Lynch Syndrome: a Tumor Biology-based Approach to Familial Colorectal Cancer
  Future Oncology (London, England). Apr, 2010  |   Pubmed ID: 20373868
• Lynch Syndrome-associated Breast Cancers: Clinicopathologic Characteristics of a Case Series from the Colon Cancer Family Registry
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Apr, 2010  |   Pubmed ID: 20215533
• Phenotypic Diversity in Patients with Multiple Serrated Polyps: a Genetics Clinic Study
  International Journal of Colorectal Disease. Jun, 2010  |   Pubmed ID: 20213458
• RAB6C is a Retrogene That Encodes a Centrosomal Protein Involved in Cell Cycle Progression
  Journal of Molecular Biology. Mar, 2010  |   Pubmed ID: 20064528
• Risks of Lynch Syndrome Cancers for MSH6 Mutation Carriers
  Journal of the National Cancer Institute. Feb, 2010  |   Pubmed ID: 20028993
• Parent of Origin Effects on Age at Colorectal Cancer Diagnosis
  International Journal of Cancer. Journal International Du Cancer. Jul, 2010  |   Pubmed ID: 19904757
• Analysis of the Association Between CIMP and BRAF in Colorectal Cancer by DNA Methylation Profiling
  PloS One. 2009  |   Pubmed ID: 20027224
• Screening for Microsatellite Instability Identifies Frequent 3'-untranslated Region Mutation of the RB1-inducible Coiled-coil 1 Gene in Colon Tumors
  PloS One. 2009  |   Pubmed ID: 19888451
• Varying Etiologies Lead to Different Molecular Changes in Australian and South African Hepatocellular Carcinomas
  International Journal of Oncology. Nov, 2009  |   Pubmed ID: 19787262
• Associations Between Smoking, Alcohol Consumption, and Colorectal Cancer, Overall and by Tumor Microsatellite Instability Status
  Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology. Oct, 2009  |   Pubmed ID: 19755657
• HLA-DR Expression is Associated with Better Prognosis in Sporadic Australian Clinicopathological Stage C Colorectal Cancers
  International Journal of Cancer. Journal International Du Cancer. Sep, 2009  |   Pubmed ID: 19462453
• Efficient Molecular Screening of Lynch Syndrome by Specific 3' Promoter Methylation of the MLH1 or BRAF Mutation in Colorectal Cancer with High-frequency Microsatellite Instability
  Oncology Reports. Jun, 2009  |   Pubmed ID: 19424639
• A Perspective on Bi-allelic MUTYH Mutations in Patients with Hyperplastic Polyposis Syndrome
  Gastroenterology. Jun, 2009  |   Pubmed ID: 19406141
• Classifying MLH1 and MSH2 Variants Using Bioinformatic Prediction, Splicing Assays, Segregation, and Tumor Characteristics
  Human Mutation. May, 2009  |   Pubmed ID: 19267393
• The Association of Tumor Microsatellite Instability Phenotype with Family History of Colorectal Cancer
  Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology. Mar, 2009  |   Pubmed ID: 19258475
• Analysis of Families with Lynch Syndrome Complicated by Advanced Serrated Neoplasia: the Importance of Pathology Review and Pedigree Analysis
  Familial Cancer. 2009  |   Pubmed ID: 19241144
• Molecular Characterization of MSI-H Colorectal Cancer by MLHI Promoter Methylation, Immunohistochemistry, and Mismatch Repair Germline Mutation Screening
  Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology. Nov, 2008  |   Pubmed ID: 18990764
• Lynch Syndrome in Women Less Than 50 Years of Age with Endometrial Cancer
  Obstetrics and Gynecology. Oct, 2008  |   Pubmed ID: 18827140
• Ethnicity and Risk for Colorectal Cancers Showing Somatic BRAF V600E Mutation or CpG Island Methylator Phenotype
  Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology. Jul, 2008  |   Pubmed ID: 18628431
• The Clinical Phenotype of Lynch Syndrome Due to Germ-line PMS2 Mutations
  Gastroenterology. Aug, 2008  |   Pubmed ID: 18602922
• Serrated Neoplasia of the Colorectum and Cigarette Smoking
  Gastroenterology. Jul, 2008  |   Pubmed ID: 18554507
• Bone Morphogenic Protein 3 Inactivation is an Early and Frequent Event in Colorectal Cancer Development
  Genes, Chromosomes & Cancer. Jun, 2008  |   Pubmed ID: 18311777
• Molecular, Pathologic, and Clinical Features of Early-onset Endometrial Cancer: Identifying Presumptive Lynch Syndrome Patients
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Mar, 2008  |   Pubmed ID: 18310315
• Hyperplastic Polyposis in the New Zealand Population: a Condition Associated with Increased Colorectal Cancer Risk and European Ancestry
  The New Zealand Medical Journal. 2007  |   Pubmed ID: 18264196
• Variants on 9p24 and 8q24 Are Associated with Risk of Colorectal Cancer: Results from the Colon Cancer Family Registry
  Cancer Research. Dec, 2007  |   Pubmed ID: 18056436
• Pathology Features in Bethesda Guidelines Predict Colorectal Cancer Microsatellite Instability: a Population-based Study
  Gastroenterology. Jul, 2007  |   Pubmed ID: 17631130
• Serrated Pathway Colorectal Cancer in the Population: Genetic Consideration
  Gut. Oct, 2007  |   Pubmed ID: 17566021
• Microsatellite Instability Markers for Identifying Early-onset Colorectal Cancers Caused by Germ-line Mutations in DNA Mismatch Repair Genes
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. May, 2007  |   Pubmed ID: 17504984
• The MUC13 Cell Surface Mucin is Highly Expressed by Human Colorectal Carcinomas
  Human Pathology. Jun, 2007  |   Pubmed ID: 17360025
• Silencing of O6-methylguanine DNA Methyltransferase in the Absence of Promoter Hypermethylation in Hepatocellular Carcinomas from Australia and South Africa
  Oncology Reports. Apr, 2007  |   Pubmed ID: 17342321
• Epigenetic Stem Cell Signature in Cancer
  Nature Genetics. Feb, 2007  |   Pubmed ID: 17200673
• Stability of BAT26 in Lynch Syndrome Colorectal Tumours
  European Journal of Human Genetics : EJHG. Feb, 2007  |   Pubmed ID: 17133259
• High Prevalence of Sessile Serrated Adenomas with BRAF Mutations: a Prospective Study of Patients Undergoing Colonoscopy
  Gastroenterology. Nov, 2006  |   Pubmed ID: 17101316
• SnoN Expression is Differently Regulated in Microsatellite Unstable Compared with Microsatellite Stable Colorectal Cancers
  BMC Cancer. 2006  |   Pubmed ID: 17062133
• The Case for a Genetic Predisposition to Serrated Neoplasia in the Colorectum: Hypothesis and Review of the Literature
  Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology. Oct, 2006  |   Pubmed ID: 17035382
• Vaccinia-virus-induced Cellular Contractility Facilitates the Subcellular Localization of the Viral Replication Sites
  Traffic (Copenhagen, Denmark). Oct, 2006  |   Pubmed ID: 16899087
• Hyperplastic Polyposis Syndrome: Phenotypic Presentations and the Role of MBD4 and MYH
  Gastroenterology. Jul, 2006  |   Pubmed ID: 16831587
• CpG Island Methylator Phenotype Underlies Sporadic Microsatellite Instability and is Tightly Associated with BRAF Mutation in Colorectal Cancer
  Nature Genetics. Jul, 2006  |   Pubmed ID: 16804544
• Low Somatic K-ras Mutation Frequency in Colorectal Cancer Diagnosed Under the Age of 45 Years
  European Journal of Cancer (Oxford, England : 1990). Jul, 2006  |   Pubmed ID: 16765042
• The PCNA-associated Factor KIAA0101/p15(PAF) Binds the Potential Tumor Suppressor Product P33ING1b
  Experimental Cell Research. Jan, 2006  |   Pubmed ID: 16288740
• DNA Methylation Patterns in Adenomas from FAP, Multiple Adenoma and Sporadic Colorectal Carcinoma Patients
  International Journal of Cancer. Journal International Du Cancer. Feb, 2006  |   Pubmed ID: 16152625
• Isolated Loss of PMS2 Expression in Colorectal Cancers: Frequency, Patient Age, and Familial Aggregation
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Sep, 2005  |   Pubmed ID: 16166421
• Use of Molecular Tumor Characteristics to Prioritize Mismatch Repair Gene Testing in Early-onset Colorectal Cancer
  Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Sep, 2005  |   Pubmed ID: 16116158
• Type 1 Protein Secretion in Bacteria, the ABC-transporter Dependent Pathway (review)
  Molecular Membrane Biology. Jan-Apr, 2005  |   Pubmed ID: 16092522
• Evidence for BRAF Mutation and Variable Levels of Microsatellite Instability in a Syndrome of Familial Colorectal Cancer
  Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. Mar, 2005  |   Pubmed ID: 15765445
• Conversion Analysis for Mutation Detection in MLH1 and MSH2 in Patients with Colorectal Cancer
  JAMA : the Journal of the American Medical Association. Feb, 2005  |   Pubmed ID: 15713769
• Regulation of Microtubule-dependent Recycling at the Trans-Golgi Network by Rab6A and Rab6A'
  Molecular Biology of the Cell. Jan, 2005  |   Pubmed ID: 15483056
• Colorectal Cancer with Mutation in BRAF, KRAS, and Wild-type with Respect to Both Oncogenes Showing Different Patterns of DNA Methylation
  Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Nov, 2004  |   Pubmed ID: 15542810
• Cadherin/catenin Complex Appears to Be Intact in Hepatocellular Carcinomas from Australia and South Africa
  Journal of Gastroenterology and Hepatology. Jun, 2004  |   Pubmed ID: 15151624
• Mapping of a Candidate Colorectal Cancer Tumor-suppressor Gene to a 900-kilobase Region on the Short Arm of Chromosome 8
  Genes, Chromosomes & Cancer. Jul, 2004  |   Pubmed ID: 15139003
• Identification of Genes Uniquely Involved in Frequent Microsatellite Instability Colon Carcinogenesis by Expression Profiling Combined with Epigenetic Scanning
  Cancer Research. Apr, 2004  |   Pubmed ID: 15059896
• Role of Inherited Defects of MYH in the Development of Sporadic Colorectal Cancer
  Genes, Chromosomes & Cancer. May, 2004  |   Pubmed ID: 15034862
• Fas Ligand and Tumour Counter-attack in Colorectal Cancer Stratified According to Microsatellite Instability Status
  The Journal of Pathology. Sep, 2003  |   Pubmed ID: 12950016
• Peutz-Jeghers Syndrome: Genetic Screening
  Expert Review of Anticancer Therapy. Aug, 2003  |   Pubmed ID: 12934663
• The Impact of Microsatellite Instability on the Molecular Phenotype of Colorectal Tumors
  Cancer Research. Aug, 2003  |   Pubmed ID: 12907634
• Analysis of the Transcription Regulator, CNOT7, As a Candidate Chromosome 8 Tumor Suppressor Gene in Colorectal Cancer
  International Journal of Cancer. Journal International Du Cancer. Sep, 2003  |   Pubmed ID: 12845644
• Mutation Searching in Colorectal Cancer Studies: Experience with a Denaturing High-pressure Liquid Chromatography System for Exon-by-exon Scanning of Tumour Suppressor Genes
  Pathology. Dec, 2002  |   Pubmed ID: 12555990
• Aberrant Methylation of the HPP1 Gene in Ulcerative Colitis-associated Colorectal Carcinoma
  Cancer Research. Dec, 2002  |   Pubmed ID: 12460892
• Morphological and Molecular Heterogeneity Within Nonmicrosatellite Instability-high Colorectal Cancer
  Cancer Research. Nov, 2002  |   Pubmed ID: 12414620
• Correspondence Re: P. Laiho Et Al., Low-level Microsatellite Instability in Most Colorectal Carcinomas. Cancer Res., 62: 1166-1170, 2002
  Cancer Research. Oct, 2002  |   Pubmed ID: 12384567
• Hypermethylation of HPP1 is Associated with HMLH1 Hypermethylation in Gastric Adenocarcinomas
  Cancer Research. Oct, 2002  |   Pubmed ID: 12384516
• Emerging Concepts in Colorectal Neoplasia
  Gastroenterology. Sep, 2002  |   Pubmed ID: 12198712
• Association of the SULT1A1 R213H Polymorphism with Colorectal Cancer
  Clinical and Experimental Pharmacology & Physiology. Sep, 2002  |   Pubmed ID: 12165038
• Instabilotyping Reveals Unique Mutational Spectra in Microsatellite-unstable Gastric Cancers
  Cancer Research. Jul, 2002  |   Pubmed ID: 12097267
• Evolution of Colorectal Cancer: Change of Pace and Change of Direction
  Journal of Gastroenterology and Hepatology. Jan, 2002  |   Pubmed ID: 11987262
• Reciprocal Relationship Between Methylation Status and Loss of Heterozygosity at the P14(ARF) Locus in Australian and South African Hepatocellular Carcinomas
  Journal of Gastroenterology and Hepatology. Mar, 2002  |   Pubmed ID: 11982701
• Immunohistochemistry Versus Microsatellite Instability Testing in Phenotyping Colorectal Tumors
  Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Feb, 2002  |   Pubmed ID: 11844828