Johan Flygare Department of Molecular Medicine and Gene Therapy Lund University Biography Publications Institution JoVE Articles Johan Flygare has not added a biography. If you are Johan Flygare and would like to personalize this page please email our Author Liaison for assistance. Publications Lentiviral Vectors with Cellular Promoters Correct Anemia and Lethal Bone Marrow Failure in a Mouse Model for Diamond-Blackfan Anemia Molecular Therapy : the Journal of the American Society of Gene Therapy. 08, 2017 | Pubmed ID: 28434866 Direct Lineage Reprogramming: a Useful Addition to the Blood Cell Research Toolbox Expert Review of Hematology. 02, 2017 | Pubmed ID: 27967256 Direct Conversion of Fibroblasts to Megakaryocyte Progenitors Cell Reports. 10, 2016 | Pubmed ID: 27732845 Defining the Minimal Factors Required for Erythropoiesis Through Direct Lineage Conversion Cell Reports. 06, 2016 | Pubmed ID: 27264182 Glucocorticoids Improve Erythroid Progenitor Maintenance and Dampen Trp53 Response in a Mouse Model of Diamond-Blackfan Anaemia British Journal of Haematology. Nov, 2015 | Pubmed ID: 26305041 Gene Therapy Cures the Anemia and Lethal Bone Marrow Failure in a Mouse Model of RPS19-deficient Diamond-Blackfan Anemia Haematologica. Dec, 2014 | Pubmed ID: 25216681 Fetal Hepatic Progenitors Support Long-term Expansion of Hematopoietic Stem Cells Experimental Hematology. May, 2013 | Pubmed ID: 23415675 Dietary L-leucine Improves the Anemia in a Mouse Model for Diamond-Blackfan Anemia Blood. Sep, 2012 | Pubmed ID: 22791294 Progress Towards Mechanism-based Treatment for Diamond-Blackfan Anemia TheScientificWorldJournal. Month, 2012 | Pubmed ID: 22619618 From Stem Cell to Red Cell: Regulation of Erythropoiesis at Multiple Levels by Multiple Proteins, RNAs, and Chromatin Modifications Blood. Dec, 2011 | Pubmed ID: 21998215 Mice with Ribosomal Protein S19 Deficiency Develop Bone Marrow Failure and Symptoms Like Patients with Diamond-Blackfan Anemia Blood. Dec, 2011 | Pubmed ID: 21989989 Gene Therapy of Diamond Blackfan Anemia CD34(+) Cells Leads to Improved Erythroid Development and Engraftment Following Transplantation Experimental Hematology. Nov, 2008 | Pubmed ID: 18715690 Ribosomal Protein S19 Deficiency Leads to Reduced Proliferation and Increased Apoptosis but Does Not Affect Terminal Erythroid Differentiation in a Cell Line Model of Diamond-Blackfan Anemia Stem Cells (Dayton, Ohio). Feb, 2008 | Pubmed ID: 17962699 Endoglin is Not Critical for Hematopoietic Stem Cell Engraftment and Reconstitution but Regulates Adult Erythroid Development Stem Cells (Dayton, Ohio). Nov, 2007 | Pubmed ID: 17673527 Diamond-Blackfan Anemia: Erythropoiesis Lost in Translation Blood. Apr, 2007 | Pubmed ID: 17164339 Human RPS19, the Gene Mutated in Diamond-Blackfan Anemia, Encodes a Ribosomal Protein Required for the Maturation of 40S Ribosomal Subunits Blood. Feb, 2007 | Pubmed ID: 16990592 Development of Cellular Models for Ribosomal Protein S19 (RPS19)-deficient Diamond-blackfan Anemia Using Inducible Expression of SiRNA Against RPS19 Molecular Therapy : the Journal of the American Society of Gene Therapy. Apr, 2005 | Pubmed ID: 15771965 Deficiency of Ribosomal Protein S19 in CD34+ Cells Generated by SiRNA Blocks Erythroid Development and Mimics Defects Seen in Diamond-Blackfan Anemia Blood. Jun, 2005 | Pubmed ID: 15626736 Lentiviral Vector Transduction of NOD/SCID Repopulating Cells Results in Multiple Vector Integrations Per Transduced Cell: Risk of Insertional Mutagenesis Blood. Feb, 2003 | Pubmed ID: 12393514 Прямые, Lineage перепрограммирование взрослых мыши фибробластов в эритроидные предшественники Melissa Ilsley1, Sandra Capellera-Garcia1, Kishori Dhulipala1, Alban Johansson1, Johan Flygare1 1Department of Molecular Medicine and Gene Therapy, Lund University JoVE 58464 Biologia dello sviluppo
Прямые, Lineage перепрограммирование взрослых мыши фибробластов в эритроидные предшественники Melissa Ilsley1, Sandra Capellera-Garcia1, Kishori Dhulipala1, Alban Johansson1, Johan Flygare1 1Department of Molecular Medicine and Gene Therapy, Lund University JoVE 58464 Biologia dello sviluppo