Juan C. Marini Children’s Nutrition Research Center Baylor College of Medicine Biography Publications Institution JoVE Articles Juan C. Marini has not added a biography. If you are Juan C. Marini and would like to personalize this page please email our Author Liaison for assistance. Publications Blood Flow Within Bioengineered 3D Printed Vascular Constructs Using the Porcine Model Frontiers in Cardiovascular Medicine. 2021 | Pubmed ID: 34164438 Correction: A Randomized Trial to Study the Comparative Efficacy of Phenylbutyrate and Benzoate on Nitrogen Excretion and Ureagenesis in Healthy Volunteers Genetics in Medicine : Official Journal of the American College of Medical Genetics. Nov, 2021 | Pubmed ID: 33958751 Pegylated Arginine Deiminase Depletes Plasma Arginine but Maintains Tissue Arginine Availability in Young Pigs American Journal of Physiology. Endocrinology and Metabolism. 03, 2021 | Pubmed ID: 33427052 Arginase II Plays a Central Role in the Sexual Dimorphism of Arginine Metabolism in C57BL/6 Mice The Journal of Nutrition. 12, 2020 | Pubmed ID: 33188387 Modeling Age-dependent Developmental Changes in the Expression of Genes Involved in Citrulline Synthesis Using Pig Enteroids Physiological Reports. 11, 2020 | Pubmed ID: 33181004 Derangement of Arginine and Related Amino Acids in Children Undergoing Surgery for Congenital Heart Disease With Cardiopulmonary Bypass Critical Care Explorations. Jul, 2020 | Pubmed ID: 32766551 Channeling of Citrulline for the Renal Synthesis of Guanidino Acetate The Journal of Nutrition. 03, 2020 | Pubmed ID: 31868220 Developmental Changes in the Utilization of Citrulline by Neonatal Pigs American Journal of Physiology. Renal Physiology. 01, 2020 | Pubmed ID: 31760772 Sex Dependent Dysregulation of Hepatic Glucose Production in Lean Type 2 Diabetic Rats Frontiers in Endocrinology. 2019 | Pubmed ID: 31447783 Cardiac-specific Ablation of Glutaredoxin 3 Leads to Cardiac Hypertrophy and Heart Failure Physiological Reports. 04, 2019 | Pubmed ID: 31033205 Differential Action of TGR5 Agonists on GLP-2 Secretion and Promotion of Intestinal Adaptation in a Piglet Short Bowel Model American Journal of Physiology. Gastrointestinal and Liver Physiology. 05, 2019 | Pubmed ID: 30920308 Citrulline Generation Test: What Does It Measure? JPEN. Journal of Parenteral and Enteral Nutrition. 08, 2019 | Pubmed ID: 30357864 Ex Vivo Enteroids Recapitulate In Vivo Citrulline Production in Mice The Journal of Nutrition. 09, 2018 | Pubmed ID: 30184221 Rapid Disruption of Genes Specifically in Livers of Mice Using Multiplex CRISPR/Cas9 Editing Gastroenterology. 12, 2018 | Pubmed ID: 30170115 Prematurity Reduces Citrulline-arginine-nitric Oxide Production and Precedes the Onset of Necrotizing Enterocolitis in Piglets American Journal of Physiology. Gastrointestinal and Liver Physiology. 10, 2018 | Pubmed ID: 30048597 The Citrulline Recycling Pathway Sustains Cardiovascular Function in Arginine-Depleted Healthy Mice, but Cannot Sustain Nitric Oxide Production During Endotoxin Challenge The Journal of Nutrition. 06, 2018 | Pubmed ID: 29878271 A Randomized Trial to Study the Comparative Efficacy of Phenylbutyrate and Benzoate on Nitrogen Excretion and Ureagenesis in Healthy Volunteers Genetics in Medicine : Official Journal of the American College of Medical Genetics. 07, 2018 | Pubmed ID: 29693650 Ablation of Arginase II Spares Arginine and Abolishes the Arginine Requirement for Growth in Male Mice The Journal of Nutrition. 08, 2017 | Pubmed ID: 28679627 The Intestinal-renal Axis for Arginine Synthesis is Present and Functional in the Neonatal Pig American Journal of Physiology. Endocrinology and Metabolism. 08, 2017 | Pubmed ID: 28611027 Plasma Glutamine Is a Minor Precursor for the Synthesis of Citrulline: A Multispecies Study The Journal of Nutrition. 04, 2017 | Pubmed ID: 28275102 Supplemental Citrulline Is More Efficient Than Arginine in Increasing Systemic Arginine Availability in Mice The Journal of Nutrition. 04, 2017 | Pubmed ID: 28179487 Loss of Glutaredoxin 3 Impedes Mammary Lobuloalveolar Development During Pregnancy and Lactation American Journal of Physiology. Endocrinology and Metabolism. Mar, 2017 | Pubmed ID: 27894063 Targeting Stromal Glutamine Synthetase in Tumors Disrupts Tumor Microenvironment-Regulated Cancer Cell Growth Cell Metabolism. 11, 2016 | Pubmed ID: 27829138 Tumor Microenvironment Derived Exosomes Pleiotropically Modulate Cancer Cell Metabolism ELife. Feb, 2016 | Pubmed ID: 26920219 Novel Lean Type 2 Diabetic Rat Model Using Gestational Low-protein Programming American Journal of Obstetrics and Gynecology. Apr, 2016 | Pubmed ID: 26874300 Interrelationships Between Glutamine and Citrulline Metabolism Current Opinion in Clinical Nutrition and Metabolic Care. Jan, 2016 | Pubmed ID: 26560519 Dietary Arginine Requirements for Growth Are Dependent on the Rate of Citrulline Production in Mice The Journal of Nutrition. Jun, 2015 | Pubmed ID: 25855119 Glutamine Supplementation, Citrulline Production, and De Novo Arginine Synthesis: is There a Relation? The American Journal of Clinical Nutrition. Apr, 2015 | Pubmed ID: 25833987 Arginine Depletion by Arginine Deiminase Does Not Affect Whole Protein Metabolism or Muscle Fractional Protein Synthesis Rate in Mice PloS One. 2015 | Pubmed ID: 25775142 Protein Requirements: Are We Ready for New Recommendations? The Journal of Nutrition. Jan, 2015 | Pubmed ID: 25342701 Extrarenal Citrulline Disposal in Mice with Impaired Renal Function American Journal of Physiology. Renal Physiology. Sep, 2014 | Pubmed ID: 25056350 Dystropathology Increases Energy Expenditure and Protein Turnover in the Mdx Mouse Model of Duchenne Muscular Dystrophy PloS One. 2014 | Pubmed ID: 24586653 De Novo Synthesis is the Main Source of Ornithine for Citrulline Production in Neonatal Pigs American Journal of Physiology. Endocrinology and Metabolism. Dec, 2012 | Pubmed ID: 23074237 A Randomized Controlled Trial to Evaluate the Effects of High-dose Versus Low-dose of Arginine Therapy on Hepatic Function Tests in Argininosuccinic Aciduria Molecular Genetics and Metabolism. Nov, 2012 | Pubmed ID: 23040521 Preventative Oral Methylthioadenosine is Anti-inflammatory and Reduces DSS-induced Colitis in Mice American Journal of Physiology. Gastrointestinal and Liver Physiology. Jul, 2012 | Pubmed ID: 22556140 Nitric-oxide Supplementation for Treatment of Long-term Complications in Argininosuccinic Aciduria American Journal of Human Genetics. May, 2012 | Pubmed ID: 22541557 Effect of Ghrelin on Glucose Regulation in Mice American Journal of Physiology. Endocrinology and Metabolism. Feb, 2012 | Pubmed ID: 22338071 Arginine and Ornithine Are the Main Precursors for Citrulline Synthesis in Mice The Journal of Nutrition. Mar, 2012 | Pubmed ID: 22323761 Requirement of Argininosuccinate Lyase for Systemic Nitric Oxide Production Nature Medicine. Dec, 2011 | Pubmed ID: 22081021 B-vitamin Deficiency is Protective Against DSS-induced Colitis in Mice American Journal of Physiology. Gastrointestinal and Liver Physiology. Aug, 2011 | Pubmed ID: 21596995 Quantitative Analysis of 15N-labeled Positional Isomers of Glutamine and Citrulline Via Electrospray Ionization Tandem Mass Spectrometry of Their Dansyl Derivatives Rapid Communications in Mass Spectrometry : RCM. May, 2011 | Pubmed ID: 21491530 Phenylbutyrate Improves Nitrogen Disposal Via an Alternative Pathway Without Eliciting an Increase in Protein Breakdown and Catabolism in Control and Ornithine Transcarbamylase-deficient Patients The American Journal of Clinical Nutrition. Jun, 2011 | Pubmed ID: 21490144 Phenylbutyrate Therapy for Maple Syrup Urine Disease Human Molecular Genetics. Feb, 2011 | Pubmed ID: 21098507 Enteral Arginase II Provides Ornithine for Citrulline Synthesis American Journal of Physiology. Endocrinology and Metabolism. Jan, 2011 | Pubmed ID: 20978229 Plasma Arginine and Ornithine Are the Main Citrulline Precursors in Mice Infused with Arginine-free Diets The Journal of Nutrition. Aug, 2010 | Pubmed ID: 20573946 Glutamine: Precursor or Nitrogen Donor for Citrulline Synthesis? American Journal of Physiology. Endocrinology and Metabolism. Jul, 2010 | Pubmed ID: 20407005 Nitrogen Transactions Along the Gastrointestinal Tract of Cattle: A Meta-analytical Approach Journal of Animal Science. Mar, 2008 | Pubmed ID: 18073282 Interaction Between Murine Spf-ash Mutation and Genetic Background Yields Different Metabolic Phenotypes American Journal of Physiology. Endocrinology and Metabolism. Dec, 2007 | Pubmed ID: 17925451 Transcriptome Profiling of the Small Intestinal Epithelium in Germfree Versus Conventional Piglets BMC Genomics. 2007 | Pubmed ID: 17615075 An Improved Analytical Method for the Determination of Urea Nitrogen Isotopomers in Biological Samples Utilizing Continuous Flow Isotope Ratio Mass Spectrometry Rapid Communications in Mass Spectrometry : RCM. 2006 | Pubmed ID: 17099932 Ornithine Restores Ureagenesis Capacity and Mitigates Hyperammonemia in Otc(spf-ash) Mice The Journal of Nutrition. Jul, 2006 | Pubmed ID: 16772445 Evaluation of Hepatic Glucose Production in a Polycystic Ovary Syndrome Mouse Model Alexandra L. Gannon1,2, Shaji K. Chacko3, Inka C. Didelija3, Juan C. Marini3,4, Chellakkan S. Blesson1,2 1Department of Reproductive Endocrinology and Infertility, Baylor College of Medicine, 2Family Fertility Center, Texas Children’s Hospital, 3Children’s Nutrition Research Center, Baylor College of Medicine, 4Critical Care Medicine, Department of Pediatrics, Baylor College of Medicine JoVE 62991 Medicina
Evaluation of Hepatic Glucose Production in a Polycystic Ovary Syndrome Mouse Model Alexandra L. Gannon1,2, Shaji K. Chacko3, Inka C. Didelija3, Juan C. Marini3,4, Chellakkan S. Blesson1,2 1Department of Reproductive Endocrinology and Infertility, Baylor College of Medicine, 2Family Fertility Center, Texas Children’s Hospital, 3Children’s Nutrition Research Center, Baylor College of Medicine, 4Critical Care Medicine, Department of Pediatrics, Baylor College of Medicine JoVE 62991 Medicina