Julia Y. Ljubimova Nanomedicine Research Center, Department of Neurosurgery Cedars-Sinai Medical Center Biography Publications Institution JoVE Articles Julia Y. Ljubimova has not added a biography. If you are Julia Y. Ljubimova and would like to personalize this page please email our Author Liaison for assistance. Publications Multilayer Films Assembled from Naturally-derived Materials for Controlled Protein Release Biomacromolecules. Jun, 2014 | Pubmed ID: 24825478 Near-infrared Imaging of Brain Tumors Using the Tumor Paint BLZ-100 to Achieve Near-complete Resection of Brain Tumors Neurosurgical Focus. Feb, 2014 | Pubmed ID: 24484247 Nanomedicine Therapeutic Approaches to Overcome Cancer Drug Resistance Advanced Drug Delivery Reviews. Nov, 2013 | Pubmed ID: 24120656 Toxicity and Efficacy Evaluation of Multiple Targeted Polymalic Acid Conjugates for Triple-negative Breast Cancer Treatment Journal of Drug Targeting. Dec, 2013 | Pubmed ID: 24032759 Polymalic Acid Nanobioconjugate for Simultaneous Immunostimulation and Inhibition of Tumor Growth in HER2/neu-positive Breast Cancer Journal of Controlled Release : Official Journal of the Controlled Release Society. Nov, 2013 | Pubmed ID: 23770212 Gene Expression Changes in Rat Brain After Short and Long Exposures to Particulate Matter in Los Angeles Basin Air: Comparison with Human Brain Tumors Experimental and Toxicologic Pathology : Official Journal of the Gesellschaft Für Toxikologische Pathologie. Nov, 2013 | Pubmed ID: 23688656 Distinct Mechanisms of Membrane Permeation Induced by Two Polymalic Acid Copolymers Biomaterials. Jan, 2013 | Pubmed ID: 23063368 Biocompatible Nanopolymers: the Next Generation of Breast Cancer Treatment? Nanomedicine (London, England). Oct, 2012 | Pubmed ID: 23148535 Cellular Delivery of Doxorubicin Via PH-Controlled Hydrazone Linkage Using Multifunctional Nano Vehicle Based on Poly(β-L-Malic Acid) International Journal of Molecular Sciences. 2012 | Pubmed ID: 23109877 Nanobiopolymer for Direct Targeting and Inhibition of EGFR Expression in Triple Negative Breast Cancer PloS One. 2012 | Pubmed ID: 22355336 The Transferrin Receptor and the Targeted Delivery of Therapeutic Agents Against Cancer Biochimica Et Biophysica Acta. Mar, 2012 | Pubmed ID: 21851850 New Functional Degradable and Bio-compatible Nanoparticles Based on Poly(malic Acid) Derivatives for Site-specific Anti-cancer Drug Delivery International Journal of Pharmaceutics. Feb, 2012 | Pubmed ID: 21550387 Poly(methyl Malate) Nanoparticles: Formation, Degradation, and Encapsulation of Anticancer Drugs Macromolecular Bioscience. Oct, 2011 | Pubmed ID: 21793213 The Optimization of Polymalic Acid Peptide Copolymers for Endosomolytic Drug Delivery Biomaterials. Aug, 2011 | Pubmed ID: 21514661 Polymalic Acid-based Nanobiopolymer Provides Efficient Systemic Breast Cancer Treatment by Inhibiting Both HER2/neu Receptor Synthesis and Activity Cancer Research. Feb, 2011 | Pubmed ID: 21303974 Nanoplatforms for Constructing New Approaches to Cancer Treatment, Imaging, and Drug Delivery: What Should Be the Policy? NeuroImage. Jan, 2011 | Pubmed ID: 20149882 Nanoconjugate Platforms Development Based in Poly(β,L-Malic Acid) Methyl Esters for Tumor Drug Delivery Journal of Nanotechnology. 2010 | Pubmed ID: 23024655 Inhibition of Brain Tumor Growth by Intravenous Poly (β-L-malic Acid) Nanobioconjugate with PH-dependent Drug Release [corrected] Proceedings of the National Academy of Sciences of the United States of America. Oct, 2010 | Pubmed ID: 20921419 Phosphodiesterase Type 5 Inhibitors Increase Herceptin Transport and Treatment Efficacy in Mouse Metastatic Brain Tumor Models PloS One. 2010 | Pubmed ID: 20419092 Temozolomide Delivery to Tumor Cells by a Multifunctional Nano Vehicle Based on Poly(β-L-malic Acid) Pharmaceutical Research. Nov, 2010 | Pubmed ID: 20387095 Adenovirus-driven Overexpression of Proteinases in Organ-cultured Normal Human Corneas Leads to Diabetic-like Changes Brain Research Bulletin. Feb, 2010 | Pubmed ID: 19828126 Poly(malic Acid) Nanoconjugates Containing Various Antibodies and Oligonucleotides for Multitargeting Drug Delivery Nanomedicine (London, England). Apr, 2008 | Pubmed ID: 18373429 Nanoconjugate Based on Polymalic Acid for Tumor Targeting Chemico-biological Interactions. Jan, 2008 | Pubmed ID: 17376417 Brain Tumor Tandem Targeting Using a Combination of Monoclonal Antibodies Attached to Biopoly(beta-L-malic Acid) Journal of Controlled Release : Official Journal of the Controlled Release Society. Oct, 2007 | Pubmed ID: 17630012 Inhibition of Laminin-8 in Vivo Using a Novel Poly(malic Acid)-based Carrier Reduces Glioma Angiogenesis Angiogenesis. 2006 | Pubmed ID: 17109197 Polycefin, a New Prototype of a Multifunctional Nanoconjugate Based on Poly(beta-L-malic Acid) for Drug Delivery Bioconjugate Chemistry. Mar-Apr, 2006 | Pubmed ID: 16536461 Changes in Laminin Isoforms Associated with Brain Tumor Invasion and Angiogenesis Frontiers in Bioscience : a Journal and Virtual Library. 2006 | Pubmed ID: 16146715 Proteinase and Growth Factor Alterations Revealed by Gene Microarray Analysis of Human Diabetic Corneas Investigative Ophthalmology & Visual Science. Oct, 2005 | Pubmed ID: 16186340 Overexpression of Beta1-chain-containing Laminins in Capillary Basement Membranes of Human Breast Cancer and Its Metastases Breast Cancer Research : BCR. 2005 | Pubmed ID: 15987446 Association Between Laminin-8 and Glial Tumor Grade, Recurrence, and Patient Survival Cancer. Aug, 2004 | Pubmed ID: 15274074 Antisense Inhibition of Laminin-8 Expression Reduces Invasion of Human Gliomas in Vitro Molecular Cancer Therapeutics. Oct, 2003 | Pubmed ID: 14578463 Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine? Julia Y. Ljubimova1, Hui Ding1, Jose Portilla-Arias1, Rameshwar Patil1, Pallavi R. Gangalum1, Alexandra Chesnokova1, Satoshi Inoue1, Arthur Rekechenetskiy1, Tala Nassoura1, Keith L. Black1, Eggehard Holler1 1Nanomedicine Research Center, Department of Neurosurgery, Cedars-Sinai Medical Center JoVE 50668 Chimica
Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine? Julia Y. Ljubimova1, Hui Ding1, Jose Portilla-Arias1, Rameshwar Patil1, Pallavi R. Gangalum1, Alexandra Chesnokova1, Satoshi Inoue1, Arthur Rekechenetskiy1, Tala Nassoura1, Keith L. Black1, Eggehard Holler1 1Nanomedicine Research Center, Department of Neurosurgery, Cedars-Sinai Medical Center JoVE 50668 Chimica