Kai Ruppert Department of Radiology University of Pennsylvania Biography Publications Institution JoVE Articles Kai Ruppert has not added a biography. If you are Kai Ruppert and would like to personalize this page please email our Author Liaison for assistance. Publications Simultaneous Quantification of Hyperpolarized Xenon-129 Ventilation and Gas Exchange with Multi-breath Xenon-polarization Transfer Contrast (XTC) MRI Magnetic Resonance in Medicine. Dec, 2023 | Pubmed ID: 37533368 Hyperpolarized Xenon-129: A New Tool to Assess Pulmonary Physiology in Patients with Pulmonary Fibrosis Biomedicines. May, 2023 | Pubmed ID: 37371626 Investigating the Impact of RF Saturation-pulse Parameters on Compartment-selective Gas-phase Depolarization with Xenon Polarization Transfer Contrast MRI Magnetic Resonance in Medicine. Dec, 2022 | Pubmed ID: 36046917 Simultaneous Imaging of Ventilation and Gas Exchange with Hyperpolarized Xe MRI for Monitoring Patients with Endobronchial Valve Interventions American Journal of Respiratory and Critical Care Medicine. May, 2022 | Pubmed ID: 35044897 Ventilation Heterogeneity Imaged by Multibreath Wash-ins of Hyperpolarized He and Xe in Healthy Rabbits The Journal of Physiology. Sep, 2021 | Pubmed ID: 34256417 Measuring Pulmonary Gas Exchange Using Compartment-selective Xenon-polarization Transfer Contrast (XTC) MRI Magnetic Resonance in Medicine. May, 2021 | Pubmed ID: 33283943 Pulmonary Pyruvate Metabolism As an Index of Inflammation and Injury in a Rat Model of Acute Respiratory Distress Syndrome NMR in Biomedicine. Nov, 2020 | Pubmed ID: 32681670 Investigating Biases in the Measurement of Apparent Alveolar Septal Wall Thickness with Hyperpolarized 129Xe MRI Magnetic Resonance in Medicine. Dec, 2020 | Pubmed ID: 32557808 Obstructions in the Lower Airways Lead to Altered Airflow Patterns in the Central Airway Respiratory Physiology & Neurobiology. Jan, 2020 | Pubmed ID: 31585172 Dynamics of the Tracheal Airway and Its Influences on Respiratory Airflows: An Exemplar Study Journal of Biomechanical Engineering. Nov, 2019 | Pubmed ID: 31074759 Quantification of Ventilation and Gas Uptake in Free-Breathing Mice With Hyperpolarized Xe MRI IEEE Transactions on Medical Imaging. Sep, 2019 | Pubmed ID: 30990426 Measurement of Regional 2D Gas Transport Efficiency in Rabbit Lung Using Hyperpolarized 129Xe MRI Scientific Reports. Feb, 2019 | Pubmed ID: 30787357 Multibreath Hyperpolarized He Imaging Scheme to Measure Alveolar Oxygen Tension and Apparent Diffusion Coefficient Academic Radiology. Mar, 2019 | Pubmed ID: 30630659 Using Hyperpolarized Xenon-129 MRI to Quantify Early-Stage Lung Disease in Smokers Academic Radiology. Mar, 2019 | Pubmed ID: 30522808 Assessment of Flip Angle-TR Equivalence for Standardized Dissolved-phase Imaging of the Lung with Hyperpolarized 129Xe MRI Magnetic Resonance in Medicine. Mar, 2019 | Pubmed ID: 30346083 Regional Investigation of Lung Function and Microstructure Parameters by Localized Xe Chemical Shift Saturation Recovery and Dissolved-phase Imaging: A Reproducibility Study Magnetic Resonance in Medicine. Jan, 2019 | Pubmed ID: 30198113 Probing Changes in Lung Physiology in COPD Using CT, Perfusion MRI, and Hyperpolarized Xenon-129 MRI Academic Radiology. Mar, 2019 | Pubmed ID: 30087065 Assessment of Pulmonary Gas Transport in Rabbits Using Hyperpolarized Xenon-129 Magnetic Resonance Imaging Scientific Reports. May, 2018 | Pubmed ID: 29743565 Rapid Assessment of Pulmonary Gas Transport with Hyperpolarized 129Xe MRI Using a 3D Radial Double Golden-means Acquisition with Variable Flip Angles Magnetic Resonance in Medicine. Dec, 2018 | Pubmed ID: 29682792 Lung Metabolism and Inflammation During Mechanical Ventilation; An Imaging Approach Scientific Reports. Feb, 2018 | Pubmed ID: 29476083 Assessing Airflow Sensitivity to Healthy and Diseased Lung Conditions in a Computational Fluid Dynamics Model Validated In Vitro Journal of Biomechanical Engineering. May, 2018 | Pubmed ID: 29305603 Hyperpolarized Helium-3 Magnetic Resonance Lung Imaging of Non-sedated Infants and Young Children: a Proof-of-concept Study Clinical Imaging. 2017 | Pubmed ID: 28646735 In Vivo Imaging of the Progression of Acute Lung Injury Using Hyperpolarized [1- C] Pyruvate Magnetic Resonance in Medicine. Dec, 2017 | Pubmed ID: 28074497 The Use of Hyperpolarized Carbon-13 Magnetic Resonance for Molecular Imaging Advanced Drug Delivery Reviews. Apr, 2017 | Pubmed ID: 27599979 Author Spotlight: Advancing Lung Disease Research with Free-Breathing Hyperpolarized Xenon-129 MRI Kai Ruppert1, Luis Loza1, Faraz Amzajerdian1, Hooman Hamedani1, Ryan Baron1, Stephen Kadlecek1, Rahim Rizi1 1Department of Radiology, University of Pennsylvania JoVE 66038 Medicina
Author Spotlight: Advancing Lung Disease Research with Free-Breathing Hyperpolarized Xenon-129 MRI Kai Ruppert1, Luis Loza1, Faraz Amzajerdian1, Hooman Hamedani1, Ryan Baron1, Stephen Kadlecek1, Rahim Rizi1 1Department of Radiology, University of Pennsylvania JoVE 66038 Medicina